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Network neighborhood for query Sequence : RED2_HUMAN

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RED2_HUMAN
SwissProt Accessions	Q9NS39	Gene names	ADARB2, ADAR3, RED2
Domain Architecture
Description	Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (dsRNA adenosine deaminase B2) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RED1_HUMAN
θ value	0 (rank : 1)	NC score	0.978747 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	29	Shared Neighborhood Hits	17
SwissProt Accessions	P78563, O00395, O00465, O00691, O00692, P78555, Q8NFD1	Gene names	ADARB1, ADAR2, DRADA2, RED1
Domain Architecture
Description	Double-stranded RNA-specific editase 1 (EC 3.5.-.-) (dsRNA adenosine deaminase) (RNA-editing deaminase 1) (RNA-editing enzyme 1).

RED1_MOUSE
θ value	0 (rank : 2)	NC score	0.982121 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	32	Shared Neighborhood Hits	17
SwissProt Accessions	Q91ZS8, Q8K3X1, Q91ZS6, Q91ZS7, Q91ZS9, Q99MU8	Gene names	Adarb1, Adar2, Red1
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-specific editase 1 (EC 3.5.-.-) (dsRNA adenosine deaminase) (RNA-editing deaminase 1) (RNA-editing enzyme 1).

RED2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NS39	Gene names	ADARB2, ADAR3, RED2
Domain Architecture
Description	Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (dsRNA adenosine deaminase B2) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2).

RED2_MOUSE
θ value	0 (rank : 4)	NC score	0.996381 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JI20, Q3UTP1, Q8CC51, Q9JIE5	Gene names	Adarb2, Adar3, Red2
Domain Architecture
Description	Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (dsRNA adenosine deaminase B2) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2).

DSRAD_HUMAN
θ value	3.24342e-66 (rank : 5)	NC score	0.845223 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	P55265, O15223, O43859, O43860, Q9BYM3, Q9BYM4	Gene names	ADAR, ADAR1, DSRAD, IFI4
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (136 kDa double-stranded RNA-binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4 protein).

DSRAD_MOUSE
θ value	1.15359e-63 (rank : 6)	NC score	0.838665 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	67	Shared Neighborhood Hits	17
SwissProt Accessions	Q99MU3, O70375, Q80UZ6, Q8C222, Q99MU2, Q99MU4, Q99MU7	Gene names	Adar
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (RNA adenosine deaminase 1).

ILF3_HUMAN
θ value	3.75424e-22 (rank : 7)	NC score	0.639237 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	Q12906, O43409, Q6P1X1, Q86XY7, Q99544, Q99545, Q9BZH4, Q9BZH5, Q9NQ95, Q9NQ96, Q9NQ97, Q9NQ98, Q9NQ99, Q9NQA0, Q9NQA1, Q9NQA2, Q9NRN2, Q9NRN3, Q9NRN4, Q9UMZ9, Q9UN00, Q9UN84, Q9UNA2	Gene names	ILF3, DRBF, MPHOSPH4, NF90
Domain Architecture
Description	Interleukin enhancer-binding factor 3 (Nuclear factor of activated T- cells 90 kDa) (NF-AT-90) (Double-stranded RNA-binding protein 76) (DRBP76) (Translational control protein 80) (TCP80) (Nuclear factor associated with dsRNA) (NFAR) (M-phase phosphoprotein 4) (MPP4).

ILF3_MOUSE
θ value	2.69047e-20 (rank : 8)	NC score	0.634155 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	71	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z1X4, Q80VD5, Q812A1, Q8BP80, Q8C2H8, Q8K588	Gene names	Ilf3
Domain Architecture
Description	Interleukin enhancer-binding factor 3.

STAU2_MOUSE
θ value	5.44631e-05 (rank : 9)	NC score	0.390454 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CJ67, Q8BSY8, Q8CJ66, Q8R175, Q91Z19, Q9D5N7	Gene names	Stau2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

STAU2_HUMAN
θ value	0.000602161 (rank : 10)	NC score	0.370259 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NUL3, Q6AHY7, Q96HM0, Q96HM1, Q9NVI5, Q9UGG6	Gene names	STAU2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

TRBP2_MOUSE
θ value	0.00228821 (rank : 11)	NC score	0.286060 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	P97473	Gene names	Tarbp2, Prbp
Domain Architecture
Description	TAR RNA-binding protein 2 (Protamine-1 RNA-binding protein) (PRM-1 RNA-binding protein).

STAU1_HUMAN
θ value	0.00869519 (rank : 12)	NC score	0.266698 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	O95793, Q6GTM4, Q9H5B4, Q9H5B5, Q9Y3Q2	Gene names	STAU1, STAU
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

STAU1_MOUSE
θ value	0.0113563 (rank : 13)	NC score	0.264935 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z108	Gene names	Stau1, Stau
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

TRBP2_HUMAN
θ value	0.0252991 (rank : 14)	NC score	0.269775 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	Q15633, Q12878	Gene names	TARBP2, TRBP
Domain Architecture
Description	TAR RNA-binding protein 2 (Trans-activation-responsive RNA-binding protein).

PRKRA_MOUSE
θ value	0.0736092 (rank : 15)	NC score	0.253547 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WTX2, Q9CZB7	Gene names	Prkra, Rax
Domain Architecture	No domain graphic available
Description	Interferon-inducible double stranded RNA-dependent protein kinase activator A (Protein kinase, interferon-inducible double stranded RNA- dependent activator) (Protein activator of the interferon-induced protein kinase) (PKR-associated protein X) (PKR-associating protein X) (RAX).

PRKRA_HUMAN
θ value	0.0961366 (rank : 16)	NC score	0.253311 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	O75569, Q53G24, Q6X7T5, Q8NDK4	Gene names	PRKRA, PACT, RAX
Domain Architecture	No domain graphic available
Description	Interferon-inducible double stranded RNA-dependent protein kinase activator A (Protein kinase, interferon-inducible double stranded RNA- dependent activator) (Protein activator of the interferon-induced protein kinase) (PKR-associated protein X) (PKR-associating protein X).

E2AK2_HUMAN
θ value	0.125558 (rank : 17)	NC score	0.030561 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	856	Shared Neighborhood Hits	17
SwissProt Accessions	P19525	Gene names	EIF2AK2, PKR, PRKR
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase).

RNC_HUMAN
θ value	0.62314 (rank : 18)	NC score	0.059914 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	176	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

MED8_MOUSE
θ value	0.813845 (rank : 19)	NC score	0.068194 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D7W5, Q3UGB4, Q99LM4, Q9JJ84	Gene names	Med8
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 8 homolog (Activator-recruited cofactor 32 kDa component) (ARC32).

MLTK_MOUSE
θ value	1.81305 (rank : 20)	NC score	0.004557 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	874	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

FOXQ1_HUMAN
θ value	4.03905 (rank : 21)	NC score	0.006571 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C009, Q9NS06	Gene names	FOXQ1, HFH1
Domain Architecture
Description	Forkhead box protein Q1 (Hepatocyte nuclear factor 3 forkhead homolog 1) (HNF-3/forkhead-like protein 1) (HFH-1).

GPC2_HUMAN
θ value	5.27518 (rank : 22)	NC score	0.008415 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N158	Gene names	GPC2
Domain Architecture	No domain graphic available
Description	Glypican-2 precursor.

SSX7_HUMAN
θ value	5.27518 (rank : 23)	NC score	0.008723 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q7RTT5	Gene names	SSX7
Domain Architecture	No domain graphic available
Description	Protein SSX7.

FOXE1_HUMAN
θ value	6.88961 (rank : 24)	NC score	0.004495 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	O00358, O75765	Gene names	FOXE1, FKHL15, TITF2, TTF2
Domain Architecture
Description	Forkhead box protein E1 (Thyroid transcription factor 2) (TTF-2) (Forkhead-related protein FKHL15).

TATD2_HUMAN
θ value	6.88961 (rank : 25)	NC score	0.031624 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q93075	Gene names	TATDN2, KIAA0218
Domain Architecture	No domain graphic available
Description	TatD DNase domain-containing deoxyribonuclease 2 (EC 3.1.21.-).

CENG1_MOUSE
θ value	8.99809 (rank : 26)	NC score	0.002505 (rank : 33)
Query Neighborhood Hits	30	Target Neighborhood Hits	531	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

MED8_HUMAN
θ value	8.99809 (rank : 27)	NC score	0.042352 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q96G25, Q96FQ4	Gene names	MED8
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 8 homolog (Activator-recruited cofactor 32 kDa component) (ARC32).

MLTK_HUMAN
θ value	8.99809 (rank : 28)	NC score	0.002753 (rank : 32)
Query Neighborhood Hits	30	Target Neighborhood Hits	911	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

POLS2_MOUSE
θ value	8.99809 (rank : 29)	NC score	0.004091 (rank : 31)
Query Neighborhood Hits	30	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

PP11_HUMAN
θ value	8.99809 (rank : 30)	NC score	0.013731 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P21128, Q2NKJ4	Gene names
Domain Architecture
Description	Placental protein 11 precursor (EC 3.4.21.-) (PP11).

ILF2_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.083156 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q12905, Q5SR10, Q5SR11, Q7L7R3, Q9BWD4, Q9P1N0	Gene names	ILF2, NF45
Domain Architecture	No domain graphic available
Description	Interleukin enhancer-binding factor 2 (Nuclear factor of activated T- cells 45 kDa).

ILF2_MOUSE
θ value	θ > 10 (rank : 32)	NC score	0.083156 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CXY6, Q3U083, Q5RKG0, Q8CCY9, Q99KS3	Gene names	Ilf2, Nf45
Domain Architecture	No domain graphic available
Description	Interleukin enhancer-binding factor 2 (Nuclear factor of activated T- cells 45 kDa).

ZBP1_MOUSE
θ value	θ > 10 (rank : 33)	NC score	0.055323 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QY24, Q8VE02, Q9D8B9	Gene names	Zbp1, Dlm1
Domain Architecture
Description	Z-DNA-binding protein 1 (Tumor stroma and activated macrophage protein DLM-1).

Hits sorted by NC score

RED2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NS39	Gene names	ADARB2, ADAR3, RED2
Domain Architecture
Description	Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (dsRNA adenosine deaminase B2) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2).

RED2_MOUSE
NC score	0.996381 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JI20, Q3UTP1, Q8CC51, Q9JIE5	Gene names	Adarb2, Adar3, Red2
Domain Architecture
Description	Double-stranded RNA-specific editase B2 (EC 3.5.-.-) (dsRNA adenosine deaminase B2) (RNA-dependent adenosine deaminase 3) (RNA-editing deaminase 2) (RNA-editing enzyme 2).

RED1_MOUSE
NC score	0.982121 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	32	Shared Neighborhood Hits	17
SwissProt Accessions	Q91ZS8, Q8K3X1, Q91ZS6, Q91ZS7, Q91ZS9, Q99MU8	Gene names	Adarb1, Adar2, Red1
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-specific editase 1 (EC 3.5.-.-) (dsRNA adenosine deaminase) (RNA-editing deaminase 1) (RNA-editing enzyme 1).

RED1_HUMAN
NC score	0.978747 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	29	Shared Neighborhood Hits	17
SwissProt Accessions	P78563, O00395, O00465, O00691, O00692, P78555, Q8NFD1	Gene names	ADARB1, ADAR2, DRADA2, RED1
Domain Architecture
Description	Double-stranded RNA-specific editase 1 (EC 3.5.-.-) (dsRNA adenosine deaminase) (RNA-editing deaminase 1) (RNA-editing enzyme 1).

DSRAD_HUMAN
NC score	0.845223 (rank : 5)	θ value	3.24342e-66 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	P55265, O15223, O43859, O43860, Q9BYM3, Q9BYM4	Gene names	ADAR, ADAR1, DSRAD, IFI4
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (136 kDa double-stranded RNA-binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4 protein).

DSRAD_MOUSE
NC score	0.838665 (rank : 6)	θ value	1.15359e-63 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	67	Shared Neighborhood Hits	17
SwissProt Accessions	Q99MU3, O70375, Q80UZ6, Q8C222, Q99MU2, Q99MU4, Q99MU7	Gene names	Adar
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (RNA adenosine deaminase 1).

ILF3_HUMAN
NC score	0.639237 (rank : 7)	θ value	3.75424e-22 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	Q12906, O43409, Q6P1X1, Q86XY7, Q99544, Q99545, Q9BZH4, Q9BZH5, Q9NQ95, Q9NQ96, Q9NQ97, Q9NQ98, Q9NQ99, Q9NQA0, Q9NQA1, Q9NQA2, Q9NRN2, Q9NRN3, Q9NRN4, Q9UMZ9, Q9UN00, Q9UN84, Q9UNA2	Gene names	ILF3, DRBF, MPHOSPH4, NF90
Domain Architecture
Description	Interleukin enhancer-binding factor 3 (Nuclear factor of activated T- cells 90 kDa) (NF-AT-90) (Double-stranded RNA-binding protein 76) (DRBP76) (Translational control protein 80) (TCP80) (Nuclear factor associated with dsRNA) (NFAR) (M-phase phosphoprotein 4) (MPP4).

ILF3_MOUSE
NC score	0.634155 (rank : 8)	θ value	2.69047e-20 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	71	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z1X4, Q80VD5, Q812A1, Q8BP80, Q8C2H8, Q8K588	Gene names	Ilf3
Domain Architecture
Description	Interleukin enhancer-binding factor 3.

STAU2_MOUSE
NC score	0.390454 (rank : 9)	θ value	5.44631e-05 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CJ67, Q8BSY8, Q8CJ66, Q8R175, Q91Z19, Q9D5N7	Gene names	Stau2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

STAU2_HUMAN
NC score	0.370259 (rank : 10)	θ value	0.000602161 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NUL3, Q6AHY7, Q96HM0, Q96HM1, Q9NVI5, Q9UGG6	Gene names	STAU2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

TRBP2_MOUSE
NC score	0.286060 (rank : 11)	θ value	0.00228821 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	16
SwissProt Accessions	P97473	Gene names	Tarbp2, Prbp
Domain Architecture
Description	TAR RNA-binding protein 2 (Protamine-1 RNA-binding protein) (PRM-1 RNA-binding protein).

TRBP2_HUMAN
NC score	0.269775 (rank : 12)	θ value	0.0252991 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	Q15633, Q12878	Gene names	TARBP2, TRBP
Domain Architecture
Description	TAR RNA-binding protein 2 (Trans-activation-responsive RNA-binding protein).

STAU1_HUMAN
NC score	0.266698 (rank : 13)	θ value	0.00869519 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	O95793, Q6GTM4, Q9H5B4, Q9H5B5, Q9Y3Q2	Gene names	STAU1, STAU
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

STAU1_MOUSE
NC score	0.264935 (rank : 14)	θ value	0.0113563 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z108	Gene names	Stau1, Stau
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

PRKRA_MOUSE
NC score	0.253547 (rank : 15)	θ value	0.0736092 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WTX2, Q9CZB7	Gene names	Prkra, Rax
Domain Architecture	No domain graphic available
Description	Interferon-inducible double stranded RNA-dependent protein kinase activator A (Protein kinase, interferon-inducible double stranded RNA- dependent activator) (Protein activator of the interferon-induced protein kinase) (PKR-associated protein X) (PKR-associating protein X) (RAX).

PRKRA_HUMAN
NC score	0.253311 (rank : 16)	θ value	0.0961366 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	O75569, Q53G24, Q6X7T5, Q8NDK4	Gene names	PRKRA, PACT, RAX
Domain Architecture	No domain graphic available
Description	Interferon-inducible double stranded RNA-dependent protein kinase activator A (Protein kinase, interferon-inducible double stranded RNA- dependent activator) (Protein activator of the interferon-induced protein kinase) (PKR-associated protein X) (PKR-associating protein X).

ILF2_HUMAN
NC score	0.083156 (rank : 17)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	30	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q12905, Q5SR10, Q5SR11, Q7L7R3, Q9BWD4, Q9P1N0	Gene names	ILF2, NF45
Domain Architecture	No domain graphic available
Description	Interleukin enhancer-binding factor 2 (Nuclear factor of activated T- cells 45 kDa).

ILF2_MOUSE
NC score	0.083156 (rank : 18)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	30	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CXY6, Q3U083, Q5RKG0, Q8CCY9, Q99KS3	Gene names	Ilf2, Nf45
Domain Architecture	No domain graphic available
Description	Interleukin enhancer-binding factor 2 (Nuclear factor of activated T- cells 45 kDa).

MED8_MOUSE
NC score	0.068194 (rank : 19)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D7W5, Q3UGB4, Q99LM4, Q9JJ84	Gene names	Med8
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 8 homolog (Activator-recruited cofactor 32 kDa component) (ARC32).

RNC_HUMAN
NC score	0.059914 (rank : 20)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	176	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

ZBP1_MOUSE
NC score	0.055323 (rank : 21)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	30	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QY24, Q8VE02, Q9D8B9	Gene names	Zbp1, Dlm1
Domain Architecture
Description	Z-DNA-binding protein 1 (Tumor stroma and activated macrophage protein DLM-1).

MED8_HUMAN
NC score	0.042352 (rank : 22)	θ value	8.99809 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q96G25, Q96FQ4	Gene names	MED8
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 8 homolog (Activator-recruited cofactor 32 kDa component) (ARC32).

TATD2_HUMAN
NC score	0.031624 (rank : 23)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q93075	Gene names	TATDN2, KIAA0218
Domain Architecture	No domain graphic available
Description	TatD DNase domain-containing deoxyribonuclease 2 (EC 3.1.21.-).

E2AK2_HUMAN
NC score	0.030561 (rank : 24)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	856	Shared Neighborhood Hits	17
SwissProt Accessions	P19525	Gene names	EIF2AK2, PKR, PRKR
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase).

PP11_HUMAN
NC score	0.013731 (rank : 25)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	P21128, Q2NKJ4	Gene names
Domain Architecture
Description	Placental protein 11 precursor (EC 3.4.21.-) (PP11).

SSX7_HUMAN
NC score	0.008723 (rank : 26)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q7RTT5	Gene names	SSX7
Domain Architecture	No domain graphic available
Description	Protein SSX7.

GPC2_HUMAN
NC score	0.008415 (rank : 27)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N158	Gene names	GPC2
Domain Architecture	No domain graphic available
Description	Glypican-2 precursor.

FOXQ1_HUMAN
NC score	0.006571 (rank : 28)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C009, Q9NS06	Gene names	FOXQ1, HFH1
Domain Architecture
Description	Forkhead box protein Q1 (Hepatocyte nuclear factor 3 forkhead homolog 1) (HNF-3/forkhead-like protein 1) (HFH-1).

MLTK_MOUSE
NC score	0.004557 (rank : 29)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	874	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

FOXE1_HUMAN
NC score	0.004495 (rank : 30)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	O00358, O75765	Gene names	FOXE1, FKHL15, TITF2, TTF2
Domain Architecture
Description	Forkhead box protein E1 (Thyroid transcription factor 2) (TTF-2) (Forkhead-related protein FKHL15).

POLS2_MOUSE
NC score	0.004091 (rank : 31)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

MLTK_HUMAN
NC score	0.002753 (rank : 32)	θ value	8.99809 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	911	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

CENG1_MOUSE
NC score	0.002505 (rank : 33)	θ value	8.99809 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	531	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).