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Network neighborhood for query Sequence : NOS3_HUMAN

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NOS3_HUMAN
SwissProt Accessions	P29474, Q13662, Q14251, Q14434	Gene names	NOS3
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NOS1_HUMAN
θ value	0 (rank : 1)	NC score	0.905420 (rank : 6)
Query Neighborhood Hits	59	Target Neighborhood Hits	218	Shared Neighborhood Hits	13
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NOS1_MOUSE
θ value	0 (rank : 2)	NC score	0.923733 (rank : 5)
Query Neighborhood Hits	59	Target Neighborhood Hits	155	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NOS2A_HUMAN
θ value	0 (rank : 3)	NC score	0.988752 (rank : 4)
Query Neighborhood Hits	59	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P35228, O60757, O94994, Q16263, Q16692, Q4TTS5	Gene names	NOS2A, NOS2
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Hepatocyte NOS) (HEP- NOS).

NOS2_MOUSE
θ value	0 (rank : 4)	NC score	0.989269 (rank : 3)
Query Neighborhood Hits	59	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	P29477, O70515, O70516, Q5SXT3, Q6P6A0, Q8R410	Gene names	Nos2, Inosl
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (MAC- NOS).

NOS3_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	59	Target Neighborhood Hits	59	Shared Neighborhood Hits	59
SwissProt Accessions	P29474, Q13662, Q14251, Q14434	Gene names	NOS3
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

NOS3_MOUSE
θ value	0 (rank : 6)	NC score	0.997165 (rank : 2)
Query Neighborhood Hits	59	Target Neighborhood Hits	63	Shared Neighborhood Hits	30
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

NCPR_HUMAN
θ value	4.84666e-62 (rank : 7)	NC score	0.874027 (rank : 8)
Query Neighborhood Hits	59	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	P16435, Q16455, Q8N181, Q9H3M8	Gene names	POR, CYPOR
Domain Architecture
Description	NADPH--cytochrome P450 reductase (EC 1.6.2.4) (CPR) (P450R).

NCPR_MOUSE
θ value	6.32992e-62 (rank : 8)	NC score	0.875554 (rank : 7)
Query Neighborhood Hits	59	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	P37040	Gene names	Por
Domain Architecture
Description	NADPH--cytochrome P450 reductase (EC 1.6.2.4) (CPR) (P450R).

MTRR_HUMAN
θ value	1.16164e-39 (rank : 9)	NC score	0.865509 (rank : 9)
Query Neighborhood Hits	59	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBK8, O60471	Gene names	MTRR
Domain Architecture
Description	Methionine synthase reductase, mitochondrial precursor (EC 1.16.1.8) (MSR).

NCOR2_MOUSE
θ value	0.47712 (rank : 10)	NC score	0.017622 (rank : 25)
Query Neighborhood Hits	59	Target Neighborhood Hits	790	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PLK3_HUMAN
θ value	0.62314 (rank : 11)	NC score	0.001908 (rank : 57)
Query Neighborhood Hits	59	Target Neighborhood Hits	865	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H4B4, Q15767, Q96CV1	Gene names	PLK3, CNK, FNK, PRK
Domain Architecture
Description	Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF- inducible kinase) (Proliferation-related kinase).

AATM_HUMAN
θ value	0.813845 (rank : 12)	NC score	0.037436 (rank : 16)
Query Neighborhood Hits	59	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P00505, Q9BWA3	Gene names	GOT2
Domain Architecture
Description	Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 2).

AATM_MOUSE
θ value	0.813845 (rank : 13)	NC score	0.040741 (rank : 15)
Query Neighborhood Hits	59	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P05202, O09188	Gene names	Got2, Got-2
Domain Architecture
Description	Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 2).

GLIS1_HUMAN
θ value	0.813845 (rank : 14)	NC score	0.003158 (rank : 55)
Query Neighborhood Hits	59	Target Neighborhood Hits	748	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NBF1, Q8N9V9	Gene names	GLIS1
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1).

PCLO_MOUSE
θ value	0.813845 (rank : 15)	NC score	0.027829 (rank : 20)
Query Neighborhood Hits	59	Target Neighborhood Hits	2275	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CABL1_HUMAN
θ value	1.38821 (rank : 16)	NC score	0.030756 (rank : 18)
Query Neighborhood Hits	59	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDN4, Q8N3Y8, Q8NA22, Q9BTG1	Gene names	CABLES1, CABLES
Domain Architecture	No domain graphic available
Description	CDK5 and ABL1 enzyme substrate 1 (Interactor with CDK3 1) (Ik3-1).

TAOK2_MOUSE
θ value	1.38821 (rank : 17)	NC score	0.003494 (rank : 53)
Query Neighborhood Hits	59	Target Neighborhood Hits	1373	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

BSN_HUMAN
θ value	1.81305 (rank : 18)	NC score	0.019843 (rank : 23)
Query Neighborhood Hits	59	Target Neighborhood Hits	1537	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

MAGE1_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.010213 (rank : 39)
Query Neighborhood Hits	59	Target Neighborhood Hits	1389	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

WIRE_MOUSE
θ value	2.36792 (rank : 20)	NC score	0.032233 (rank : 17)
Query Neighborhood Hits	59	Target Neighborhood Hits	310	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

BAT3_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.014787 (rank : 29)
Query Neighborhood Hits	59	Target Neighborhood Hits	490	Shared Neighborhood Hits	17
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CROCC_MOUSE
θ value	3.0926 (rank : 22)	NC score	0.002540 (rank : 56)
Query Neighborhood Hits	59	Target Neighborhood Hits	1460	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

FA47A_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.016097 (rank : 28)
Query Neighborhood Hits	59	Target Neighborhood Hits	451	Shared Neighborhood Hits	21
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

MSX3_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.006373 (rank : 49)
Query Neighborhood Hits	59	Target Neighborhood Hits	330	Shared Neighborhood Hits	3
SwissProt Accessions	P70354, P70246, Q03360, Q80W10	Gene names	Msx3, Msx-3
Domain Architecture
Description	Homeobox protein MSX-3.

WIRE_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.028963 (rank : 19)
Query Neighborhood Hits	59	Target Neighborhood Hits	329	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

ATX2L_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.018225 (rank : 24)
Query Neighborhood Hits	59	Target Neighborhood Hits	401	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

CAP1_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.013724 (rank : 30)
Query Neighborhood Hits	59	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q01518, Q53HR7, Q5T0S1, Q6I9U6	Gene names	CAP1, CAP
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

CIC_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.009127 (rank : 41)
Query Neighborhood Hits	59	Target Neighborhood Hits	992	Shared Neighborhood Hits	26
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

TAOK3_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.001767 (rank : 58)
Query Neighborhood Hits	59	Target Neighborhood Hits	1494	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

BC11B_MOUSE
θ value	5.27518 (rank : 30)	NC score	0.000008 (rank : 63)
Query Neighborhood Hits	59	Target Neighborhood Hits	767	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PV8, Q8C2I1, Q99PV6, Q99PV7, Q9JLF8	Gene names	Bcl11b, Ctip2, Rit1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (mRit1) (COUP-TF-interacting protein 2).

CSKI1_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.007556 (rank : 44)
Query Neighborhood Hits	59	Target Neighborhood Hits	997	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DVL2_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.043857 (rank : 14)
Query Neighborhood Hits	59	Target Neighborhood Hits	223	Shared Neighborhood Hits	10
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

EPHB6_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.000821 (rank : 62)
Query Neighborhood Hits	59	Target Neighborhood Hits	912	Shared Neighborhood Hits	8
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

K1543_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.012344 (rank : 32)
Query Neighborhood Hits	59	Target Neighborhood Hits	435	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LIPS_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.011995 (rank : 33)
Query Neighborhood Hits	59	Target Neighborhood Hits	314	Shared Neighborhood Hits	11
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

WBP11_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.023633 (rank : 21)
Query Neighborhood Hits	59	Target Neighborhood Hits	354	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

ZYX_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.008386 (rank : 42)
Query Neighborhood Hits	59	Target Neighborhood Hits	387	Shared Neighborhood Hits	11
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

AL2S4_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.010787 (rank : 37)
Query Neighborhood Hits	59	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

CSKI2_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.004629 (rank : 52)
Query Neighborhood Hits	59	Target Neighborhood Hits	747	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

DDEF2_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.006517 (rank : 48)
Query Neighborhood Hits	59	Target Neighborhood Hits	599	Shared Neighborhood Hits	15
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

EPS8_MOUSE
θ value	6.88961 (rank : 41)	NC score	0.009964 (rank : 40)
Query Neighborhood Hits	59	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

HCLS1_MOUSE
θ value	6.88961 (rank : 42)	NC score	0.005461 (rank : 50)
Query Neighborhood Hits	59	Target Neighborhood Hits	329	Shared Neighborhood Hits	9
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

PKHA6_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.006597 (rank : 47)
Query Neighborhood Hits	59	Target Neighborhood Hits	556	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PON1_HUMAN
θ value	6.88961 (rank : 44)	NC score	0.006759 (rank : 46)
Query Neighborhood Hits	59	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P27169, Q16052	Gene names	PON1, PON
Domain Architecture
Description	Serum paraoxonase/arylesterase 1 (EC 3.1.1.2) (EC 3.1.8.1) (PON 1) (Serum aryldialkylphosphatase 1) (A-esterase 1) (Aromatic esterase 1) (K-45).

PRB3_HUMAN
θ value	6.88961 (rank : 45)	NC score	0.016817 (rank : 26)
Query Neighborhood Hits	59	Target Neighborhood Hits	318	Shared Neighborhood Hits	14
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRR3_MOUSE
θ value	6.88961 (rank : 46)	NC score	0.012927 (rank : 31)
Query Neighborhood Hits	59	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q811B5, Q91YI5	Gene names	Prr3, Cat56
Domain Architecture	No domain graphic available
Description	Proline-rich protein 3 (MHC class I region proline-rich protein CAT56).

TAOK3_MOUSE
θ value	6.88961 (rank : 47)	NC score	0.001527 (rank : 59)
Query Neighborhood Hits	59	Target Neighborhood Hits	1458	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

ZO1_MOUSE
θ value	6.88961 (rank : 48)	NC score	0.011320 (rank : 34)
Query Neighborhood Hits	59	Target Neighborhood Hits	453	Shared Neighborhood Hits	8
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

CAP1_MOUSE
θ value	8.99809 (rank : 49)	NC score	0.011191 (rank : 35)
Query Neighborhood Hits	59	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	P40124	Gene names	Cap1, Cap
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

CO4A2_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.001455 (rank : 60)
Query Neighborhood Hits	59	Target Neighborhood Hits	454	Shared Neighborhood Hits	13
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

CT151_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.010370 (rank : 38)
Query Neighborhood Hits	59	Target Neighborhood Hits	382	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

DNMBP_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.003261 (rank : 54)
Query Neighborhood Hits	59	Target Neighborhood Hits	413	Shared Neighborhood Hits	6
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

EPHB6_MOUSE
θ value	8.99809 (rank : 53)	NC score	0.001258 (rank : 61)
Query Neighborhood Hits	59	Target Neighborhood Hits	906	Shared Neighborhood Hits	10
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

FBLI1_MOUSE
θ value	8.99809 (rank : 54)	NC score	0.007136 (rank : 45)
Query Neighborhood Hits	59	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

GGA3_MOUSE
θ value	8.99809 (rank : 55)	NC score	0.005400 (rank : 51)
Query Neighborhood Hits	59	Target Neighborhood Hits	148	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

PCLO_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.011084 (rank : 36)
Query Neighborhood Hits	59	Target Neighborhood Hits	2046	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

TAU_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.008168 (rank : 43)
Query Neighborhood Hits	59	Target Neighborhood Hits	448	Shared Neighborhood Hits	19
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

WASF2_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.016696 (rank : 27)
Query Neighborhood Hits	59	Target Neighborhood Hits	315	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WBP11_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.021222 (rank : 22)
Query Neighborhood Hits	59	Target Neighborhood Hits	362	Shared Neighborhood Hits	16
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

SNTB1_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.050838 (rank : 12)
Query Neighborhood Hits	59	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB1_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.051022 (rank : 11)
Query Neighborhood Hits	59	Target Neighborhood Hits	160	Shared Neighborhood Hits	6
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

SNTB2_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.050250 (rank : 13)
Query Neighborhood Hits	59	Target Neighborhood Hits	180	Shared Neighborhood Hits	7
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB2_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.051312 (rank : 10)
Query Neighborhood Hits	59	Target Neighborhood Hits	181	Shared Neighborhood Hits	5
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

Hits sorted by NC score

NOS3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	59	Target Neighborhood Hits	59	Shared Neighborhood Hits	59
SwissProt Accessions	P29474, Q13662, Q14251, Q14434	Gene names	NOS3
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

NOS3_MOUSE
NC score	0.997165 (rank : 2)	θ value	0 (rank : 6)
Query Neighborhood Hits	59	Target Neighborhood Hits	63	Shared Neighborhood Hits	30
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

NOS2_MOUSE
NC score	0.989269 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	59	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	P29477, O70515, O70516, Q5SXT3, Q6P6A0, Q8R410	Gene names	Nos2, Inosl
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (MAC- NOS).

NOS2A_HUMAN
NC score	0.988752 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	59	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P35228, O60757, O94994, Q16263, Q16692, Q4TTS5	Gene names	NOS2A, NOS2
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Hepatocyte NOS) (HEP- NOS).

NOS1_MOUSE
NC score	0.923733 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	59	Target Neighborhood Hits	155	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NOS1_HUMAN
NC score	0.905420 (rank : 6)	θ value	0 (rank : 1)
Query Neighborhood Hits	59	Target Neighborhood Hits	218	Shared Neighborhood Hits	13
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NCPR_MOUSE
NC score	0.875554 (rank : 7)	θ value	6.32992e-62 (rank : 8)
Query Neighborhood Hits	59	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	P37040	Gene names	Por
Domain Architecture
Description	NADPH--cytochrome P450 reductase (EC 1.6.2.4) (CPR) (P450R).

NCPR_HUMAN
NC score	0.874027 (rank : 8)	θ value	4.84666e-62 (rank : 7)
Query Neighborhood Hits	59	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	P16435, Q16455, Q8N181, Q9H3M8	Gene names	POR, CYPOR
Domain Architecture
Description	NADPH--cytochrome P450 reductase (EC 1.6.2.4) (CPR) (P450R).

MTRR_HUMAN
NC score	0.865509 (rank : 9)	θ value	1.16164e-39 (rank : 9)
Query Neighborhood Hits	59	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBK8, O60471	Gene names	MTRR
Domain Architecture
Description	Methionine synthase reductase, mitochondrial precursor (EC 1.16.1.8) (MSR).

SNTB2_MOUSE
NC score	0.051312 (rank : 10)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	59	Target Neighborhood Hits	181	Shared Neighborhood Hits	5
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

SNTB1_MOUSE
NC score	0.051022 (rank : 11)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	59	Target Neighborhood Hits	160	Shared Neighborhood Hits	6
SwissProt Accessions	Q99L88, O35925	Gene names	Sntb1, Snt2b1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin 2).

SNTB1_HUMAN
NC score	0.050838 (rank : 12)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	59	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q13884, O14912, Q4KMG8	Gene names	SNTB1, SNT2B1
Domain Architecture
Description	Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Tax interaction protein 43) (TIP-43) (Syntrophin 2) (BSYN2).

SNTB2_HUMAN
NC score	0.050250 (rank : 13)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	59	Target Neighborhood Hits	180	Shared Neighborhood Hits	7
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

DVL2_HUMAN
NC score	0.043857 (rank : 14)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	59	Target Neighborhood Hits	223	Shared Neighborhood Hits	10
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

AATM_MOUSE
NC score	0.040741 (rank : 15)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	59	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P05202, O09188	Gene names	Got2, Got-2
Domain Architecture
Description	Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 2).

AATM_HUMAN
NC score	0.037436 (rank : 16)	θ value	0.813845 (rank : 12)
Query Neighborhood Hits	59	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P00505, Q9BWA3	Gene names	GOT2
Domain Architecture
Description	Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 2).

WIRE_MOUSE
NC score	0.032233 (rank : 17)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	59	Target Neighborhood Hits	310	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

CABL1_HUMAN
NC score	0.030756 (rank : 18)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	59	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDN4, Q8N3Y8, Q8NA22, Q9BTG1	Gene names	CABLES1, CABLES
Domain Architecture	No domain graphic available
Description	CDK5 and ABL1 enzyme substrate 1 (Interactor with CDK3 1) (Ik3-1).

WIRE_HUMAN
NC score	0.028963 (rank : 19)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	59	Target Neighborhood Hits	329	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

PCLO_MOUSE
NC score	0.027829 (rank : 20)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	59	Target Neighborhood Hits	2275	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

WBP11_HUMAN
NC score	0.023633 (rank : 21)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	59	Target Neighborhood Hits	354	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
NC score	0.021222 (rank : 22)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	59	Target Neighborhood Hits	362	Shared Neighborhood Hits	16
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

BSN_HUMAN
NC score	0.019843 (rank : 23)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	59	Target Neighborhood Hits	1537	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

ATX2L_MOUSE
NC score	0.018225 (rank : 24)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	59	Target Neighborhood Hits	401	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

NCOR2_MOUSE
NC score	0.017622 (rank : 25)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	59	Target Neighborhood Hits	790	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PRB3_HUMAN
NC score	0.016817 (rank : 26)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	59	Target Neighborhood Hits	318	Shared Neighborhood Hits	14
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

WASF2_MOUSE
NC score	0.016696 (rank : 27)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	59	Target Neighborhood Hits	315	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

FA47A_HUMAN
NC score	0.016097 (rank : 28)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	59	Target Neighborhood Hits	451	Shared Neighborhood Hits	21
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

BAT3_HUMAN
NC score	0.014787 (rank : 29)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	59	Target Neighborhood Hits	490	Shared Neighborhood Hits	17
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CAP1_HUMAN
NC score	0.013724 (rank : 30)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	59	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q01518, Q53HR7, Q5T0S1, Q6I9U6	Gene names	CAP1, CAP
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

PRR3_MOUSE
NC score	0.012927 (rank : 31)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	59	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q811B5, Q91YI5	Gene names	Prr3, Cat56
Domain Architecture	No domain graphic available
Description	Proline-rich protein 3 (MHC class I region proline-rich protein CAT56).

K1543_HUMAN
NC score	0.012344 (rank : 32)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	59	Target Neighborhood Hits	435	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LIPS_HUMAN
NC score	0.011995 (rank : 33)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	59	Target Neighborhood Hits	314	Shared Neighborhood Hits	11
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

ZO1_MOUSE
NC score	0.011320 (rank : 34)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	59	Target Neighborhood Hits	453	Shared Neighborhood Hits	8
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

CAP1_MOUSE
NC score	0.011191 (rank : 35)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	59	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	P40124	Gene names	Cap1, Cap
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

PCLO_HUMAN
NC score	0.011084 (rank : 36)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	59	Target Neighborhood Hits	2046	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

AL2S4_MOUSE
NC score	0.010787 (rank : 37)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	59	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

CT151_HUMAN
NC score	0.010370 (rank : 38)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	59	Target Neighborhood Hits	382	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

MAGE1_HUMAN
NC score	0.010213 (rank : 39)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	59	Target Neighborhood Hits	1389	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

EPS8_MOUSE
NC score	0.009964 (rank : 40)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	59	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q08509	Gene names	Eps8
Domain Architecture
Description	Epidermal growth factor receptor kinase substrate 8.

CIC_HUMAN
NC score	0.009127 (rank : 41)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	59	Target Neighborhood Hits	992	Shared Neighborhood Hits	26
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ZYX_HUMAN
NC score	0.008386 (rank : 42)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	59	Target Neighborhood Hits	387	Shared Neighborhood Hits	11
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

TAU_HUMAN
NC score	0.008168 (rank : 43)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	59	Target Neighborhood Hits	448	Shared Neighborhood Hits	19
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

CSKI1_HUMAN
NC score	0.007556 (rank : 44)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	59	Target Neighborhood Hits	997	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

FBLI1_MOUSE
NC score	0.007136 (rank : 45)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	59	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

PON1_HUMAN
NC score	0.006759 (rank : 46)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	59	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P27169, Q16052	Gene names	PON1, PON
Domain Architecture
Description	Serum paraoxonase/arylesterase 1 (EC 3.1.1.2) (EC 3.1.8.1) (PON 1) (Serum aryldialkylphosphatase 1) (A-esterase 1) (Aromatic esterase 1) (K-45).

PKHA6_HUMAN
NC score	0.006597 (rank : 47)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	59	Target Neighborhood Hits	556	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

DDEF2_HUMAN
NC score	0.006517 (rank : 48)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	59	Target Neighborhood Hits	599	Shared Neighborhood Hits	15
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

MSX3_MOUSE
NC score	0.006373 (rank : 49)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	59	Target Neighborhood Hits	330	Shared Neighborhood Hits	3
SwissProt Accessions	P70354, P70246, Q03360, Q80W10	Gene names	Msx3, Msx-3
Domain Architecture
Description	Homeobox protein MSX-3.

HCLS1_MOUSE
NC score	0.005461 (rank : 50)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	59	Target Neighborhood Hits	329	Shared Neighborhood Hits	9
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

GGA3_MOUSE
NC score	0.005400 (rank : 51)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	59	Target Neighborhood Hits	148	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

CSKI2_HUMAN
NC score	0.004629 (rank : 52)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	59	Target Neighborhood Hits	747	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

TAOK2_MOUSE
NC score	0.003494 (rank : 53)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	59	Target Neighborhood Hits	1373	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

DNMBP_HUMAN
NC score	0.003261 (rank : 54)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	59	Target Neighborhood Hits	413	Shared Neighborhood Hits	6
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

GLIS1_HUMAN
NC score	0.003158 (rank : 55)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	59	Target Neighborhood Hits	748	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NBF1, Q8N9V9	Gene names	GLIS1
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1).

CROCC_MOUSE
NC score	0.002540 (rank : 56)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	59	Target Neighborhood Hits	1460	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

PLK3_HUMAN
NC score	0.001908 (rank : 57)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	59	Target Neighborhood Hits	865	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H4B4, Q15767, Q96CV1	Gene names	PLK3, CNK, FNK, PRK
Domain Architecture
Description	Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Polo-like kinase 3) (PLK-3) (Cytokine-inducible serine/threonine-protein kinase) (FGF- inducible kinase) (Proliferation-related kinase).

TAOK3_HUMAN
NC score	0.001767 (rank : 58)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	59	Target Neighborhood Hits	1494	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

TAOK3_MOUSE
NC score	0.001527 (rank : 59)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	59	Target Neighborhood Hits	1458	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

CO4A2_HUMAN
NC score	0.001455 (rank : 60)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	59	Target Neighborhood Hits	454	Shared Neighborhood Hits	13
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

EPHB6_MOUSE
NC score	0.001258 (rank : 61)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	59	Target Neighborhood Hits	906	Shared Neighborhood Hits	10
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

EPHB6_HUMAN
NC score	0.000821 (rank : 62)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	59	Target Neighborhood Hits	912	Shared Neighborhood Hits	8
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

BC11B_MOUSE
NC score	0.000008 (rank : 63)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	59	Target Neighborhood Hits	767	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PV8, Q8C2I1, Q99PV6, Q99PV7, Q9JLF8	Gene names	Bcl11b, Ctip2, Rit1
Domain Architecture	No domain graphic available
Description	B-cell lymphoma/leukemia 11B (B-cell CLL/lymphoma 11B) (Radiation- induced tumor suppressor gene 1 protein) (mRit1) (COUP-TF-interacting protein 2).