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Network neighborhood for query Sequence : NOS2A_HUMAN

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NOS2A_HUMAN
SwissProt Accessions	P35228, O60757, O94994, Q16263, Q16692, Q4TTS5	Gene names	NOS2A, NOS2
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Hepatocyte NOS) (HEP- NOS).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NOS1_HUMAN
θ value	0 (rank : 1)	NC score	0.903563 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	218	Shared Neighborhood Hits	9
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NOS1_MOUSE
θ value	0 (rank : 2)	NC score	0.921964 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NOS2A_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	P35228, O60757, O94994, Q16263, Q16692, Q4TTS5	Gene names	NOS2A, NOS2
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Hepatocyte NOS) (HEP- NOS).

NOS2_MOUSE
θ value	0 (rank : 4)	NC score	0.997870 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	24	Shared Neighborhood Hits	10
SwissProt Accessions	P29477, O70515, O70516, Q5SXT3, Q6P6A0, Q8R410	Gene names	Nos2, Inosl
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (MAC- NOS).

NOS3_HUMAN
θ value	0 (rank : 5)	NC score	0.988752 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	59	Shared Neighborhood Hits	9
SwissProt Accessions	P29474, Q13662, Q14251, Q14434	Gene names	NOS3
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

NOS3_MOUSE
θ value	0 (rank : 6)	NC score	0.988307 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

NCPR_MOUSE
θ value	3.58603e-65 (rank : 7)	NC score	0.882399 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	P37040	Gene names	Por
Domain Architecture
Description	NADPH--cytochrome P450 reductase (EC 1.6.2.4) (CPR) (P450R).

NCPR_HUMAN
θ value	6.11685e-65 (rank : 8)	NC score	0.880672 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	P16435, Q16455, Q8N181, Q9H3M8	Gene names	POR, CYPOR
Domain Architecture
Description	NADPH--cytochrome P450 reductase (EC 1.6.2.4) (CPR) (P450R).

MTRR_HUMAN
θ value	1.41672e-45 (rank : 9)	NC score	0.875527 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBK8, O60471	Gene names	MTRR
Domain Architecture
Description	Methionine synthase reductase, mitochondrial precursor (EC 1.16.1.8) (MSR).

MUC1_MOUSE
θ value	0.0961366 (rank : 10)	NC score	0.029864 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	388	Shared Neighborhood Hits	2
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

K1688_MOUSE
θ value	0.365318 (rank : 11)	NC score	0.020633 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	188	Shared Neighborhood Hits	2
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

CLR59_HUMAN
θ value	0.62314 (rank : 12)	NC score	0.017145 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

TREA_MOUSE
θ value	0.62314 (rank : 13)	NC score	0.027301 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLT2, Q91ZS4	Gene names	Treh
Domain Architecture
Description	Trehalase precursor (EC 3.2.1.28) (Alpha,alpha-trehalase) (Alpha,alpha-trehalose glucohydrolase).

SEL1L_HUMAN
θ value	2.36792 (rank : 14)	NC score	0.013763 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBV2, Q6UWT6, Q9P1T9, Q9UHK7	Gene names	SEL1L, TSA305
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

SEM3E_MOUSE
θ value	3.0926 (rank : 15)	NC score	0.004613 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).

EFCB2_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.025560 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VUJ9, Q59G23, Q9BS36	Gene names	EFCAB2
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 2.

PUR1_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.018613 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q06203	Gene names	PPAT, GPAT
Domain Architecture
Description	Amidophosphoribosyltransferase precursor (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (GPAT).

ZN711_HUMAN
θ value	4.03905 (rank : 18)	NC score	-0.000885 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	751	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y462, Q6NX42, Q9Y4J6	Gene names	ZNF711, CMPX1, ZNF6
Domain Architecture
Description	Zinc finger protein 711 (Zinc finger protein 6).

LCMT2_MOUSE
θ value	5.27518 (rank : 19)	NC score	0.011339 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYR1, Q3T9F7, Q6A048, Q8BIG6	Gene names	Lcmt2, Kiaa0547
Domain Architecture	No domain graphic available
Description	Leucine carboxyl methyltransferase 2 (EC 2.1.1.-) (p21WAF1/CIP1 promoter-interacting protein).

PCNT_MOUSE
θ value	6.88961 (rank : 20)	NC score	0.001017 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	1207	Shared Neighborhood Hits	2
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

ANPRB_HUMAN
θ value	8.99809 (rank : 21)	NC score	-0.000166 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	646	Shared Neighborhood Hits	2
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

Hits sorted by NC score

NOS2A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	P35228, O60757, O94994, Q16263, Q16692, Q4TTS5	Gene names	NOS2A, NOS2
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Hepatocyte NOS) (HEP- NOS).

NOS2_MOUSE
NC score	0.997870 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	24	Shared Neighborhood Hits	10
SwissProt Accessions	P29477, O70515, O70516, Q5SXT3, Q6P6A0, Q8R410	Gene names	Nos2, Inosl
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (MAC- NOS).

NOS3_HUMAN
NC score	0.988752 (rank : 3)	θ value	0 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	59	Shared Neighborhood Hits	9
SwissProt Accessions	P29474, Q13662, Q14251, Q14434	Gene names	NOS3
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

NOS3_MOUSE
NC score	0.988307 (rank : 4)	θ value	0 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

NOS1_MOUSE
NC score	0.921964 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NOS1_HUMAN
NC score	0.903563 (rank : 6)	θ value	0 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	218	Shared Neighborhood Hits	9
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

NCPR_MOUSE
NC score	0.882399 (rank : 7)	θ value	3.58603e-65 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	P37040	Gene names	Por
Domain Architecture
Description	NADPH--cytochrome P450 reductase (EC 1.6.2.4) (CPR) (P450R).

NCPR_HUMAN
NC score	0.880672 (rank : 8)	θ value	6.11685e-65 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	P16435, Q16455, Q8N181, Q9H3M8	Gene names	POR, CYPOR
Domain Architecture
Description	NADPH--cytochrome P450 reductase (EC 1.6.2.4) (CPR) (P450R).

MTRR_HUMAN
NC score	0.875527 (rank : 9)	θ value	1.41672e-45 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBK8, O60471	Gene names	MTRR
Domain Architecture
Description	Methionine synthase reductase, mitochondrial precursor (EC 1.16.1.8) (MSR).

MUC1_MOUSE
NC score	0.029864 (rank : 10)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	388	Shared Neighborhood Hits	2
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

TREA_MOUSE
NC score	0.027301 (rank : 11)	θ value	0.62314 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLT2, Q91ZS4	Gene names	Treh
Domain Architecture
Description	Trehalase precursor (EC 3.2.1.28) (Alpha,alpha-trehalase) (Alpha,alpha-trehalose glucohydrolase).

EFCB2_HUMAN
NC score	0.025560 (rank : 12)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VUJ9, Q59G23, Q9BS36	Gene names	EFCAB2
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 2.

K1688_MOUSE
NC score	0.020633 (rank : 13)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	188	Shared Neighborhood Hits	2
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

PUR1_HUMAN
NC score	0.018613 (rank : 14)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q06203	Gene names	PPAT, GPAT
Domain Architecture
Description	Amidophosphoribosyltransferase precursor (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (GPAT).

CLR59_HUMAN
NC score	0.017145 (rank : 15)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

SEL1L_HUMAN
NC score	0.013763 (rank : 16)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBV2, Q6UWT6, Q9P1T9, Q9UHK7	Gene names	SEL1L, TSA305
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

LCMT2_MOUSE
NC score	0.011339 (rank : 17)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYR1, Q3T9F7, Q6A048, Q8BIG6	Gene names	Lcmt2, Kiaa0547
Domain Architecture	No domain graphic available
Description	Leucine carboxyl methyltransferase 2 (EC 2.1.1.-) (p21WAF1/CIP1 promoter-interacting protein).

SEM3E_MOUSE
NC score	0.004613 (rank : 18)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).

PCNT_MOUSE
NC score	0.001017 (rank : 19)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	1207	Shared Neighborhood Hits	2
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

ANPRB_HUMAN
NC score	-0.000166 (rank : 20)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	646	Shared Neighborhood Hits	2
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ZN711_HUMAN
NC score	-0.000885 (rank : 21)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	751	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y462, Q6NX42, Q9Y4J6	Gene names	ZNF711, CMPX1, ZNF6
Domain Architecture
Description	Zinc finger protein 711 (Zinc finger protein 6).