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Network neighborhood for query Sequence : TREA_MOUSE

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TREA_MOUSE
SwissProt Accessions	Q9JLT2, Q91ZS4	Gene names	Treh
Domain Architecture
Description	Trehalase precursor (EC 3.2.1.28) (Alpha,alpha-trehalase) (Alpha,alpha-trehalose glucohydrolase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TREA_HUMAN
θ value	0 (rank : 1)	NC score	0.995036 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	O43280	Gene names	TREH, TREA
Domain Architecture
Description	Trehalase precursor (EC 3.2.1.28) (Alpha,alpha-trehalase) (Alpha,alpha-trehalose glucohydrolase).

TREA_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JLT2, Q91ZS4	Gene names	Treh
Domain Architecture
Description	Trehalase precursor (EC 3.2.1.28) (Alpha,alpha-trehalase) (Alpha,alpha-trehalose glucohydrolase).

SPTB1_MOUSE
θ value	0.365318 (rank : 3)	NC score	0.016471 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	543	Shared Neighborhood Hits	2
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

DAXX_MOUSE
θ value	0.47712 (rank : 4)	NC score	0.061211 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	173	Shared Neighborhood Hits	3
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

NOS2A_HUMAN
θ value	0.62314 (rank : 5)	NC score	0.027301 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P35228, O60757, O94994, Q16263, Q16692, Q4TTS5	Gene names	NOS2A, NOS2
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Hepatocyte NOS) (HEP- NOS).

PSA_HUMAN
θ value	2.36792 (rank : 6)	NC score	0.025295 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P55786, Q6P145, Q9NP16, Q9UEM2	Gene names	NPEPPS, PSA
Domain Architecture
Description	Puromycin-sensitive aminopeptidase (EC 3.4.11.-) (PSA).

PSA_MOUSE
θ value	2.36792 (rank : 7)	NC score	0.025329 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q11011, Q91VJ8	Gene names	Npepps, Psa
Domain Architecture
Description	Puromycin-sensitive aminopeptidase (EC 3.4.11.-) (PSA).

DAXX_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.045952 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	207	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

ES8L1_HUMAN
θ value	5.27518 (rank : 9)	NC score	0.013471 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	162	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

BRCA2_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.016524 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	202	Shared Neighborhood Hits	3
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

CATL2_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.008437 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	O60911, O60233, Q5T1U0	Gene names	CTSL2, CATL2, CTSU, CTSV
Domain Architecture
Description	Cathepsin L2 precursor (EC 3.4.22.43) (Cathepsin V) (Cathepsin U).

BRCA1_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.010131 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	381	Shared Neighborhood Hits	3
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

Hits sorted by NC score

TREA_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JLT2, Q91ZS4	Gene names	Treh
Domain Architecture
Description	Trehalase precursor (EC 3.2.1.28) (Alpha,alpha-trehalase) (Alpha,alpha-trehalose glucohydrolase).

TREA_HUMAN
NC score	0.995036 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	O43280	Gene names	TREH, TREA
Domain Architecture
Description	Trehalase precursor (EC 3.2.1.28) (Alpha,alpha-trehalase) (Alpha,alpha-trehalose glucohydrolase).

DAXX_MOUSE
NC score	0.061211 (rank : 3)	θ value	0.47712 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	173	Shared Neighborhood Hits	3
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

DAXX_HUMAN
NC score	0.045952 (rank : 4)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	207	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

NOS2A_HUMAN
NC score	0.027301 (rank : 5)	θ value	0.62314 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P35228, O60757, O94994, Q16263, Q16692, Q4TTS5	Gene names	NOS2A, NOS2
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Hepatocyte NOS) (HEP- NOS).

PSA_MOUSE
NC score	0.025329 (rank : 6)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q11011, Q91VJ8	Gene names	Npepps, Psa
Domain Architecture
Description	Puromycin-sensitive aminopeptidase (EC 3.4.11.-) (PSA).

PSA_HUMAN
NC score	0.025295 (rank : 7)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P55786, Q6P145, Q9NP16, Q9UEM2	Gene names	NPEPPS, PSA
Domain Architecture
Description	Puromycin-sensitive aminopeptidase (EC 3.4.11.-) (PSA).

BRCA2_HUMAN
NC score	0.016524 (rank : 8)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	202	Shared Neighborhood Hits	3
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

SPTB1_MOUSE
NC score	0.016471 (rank : 9)	θ value	0.365318 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	543	Shared Neighborhood Hits	2
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

ES8L1_HUMAN
NC score	0.013471 (rank : 10)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	162	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

BRCA1_HUMAN
NC score	0.010131 (rank : 11)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	381	Shared Neighborhood Hits	3
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

CATL2_HUMAN
NC score	0.008437 (rank : 12)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	O60911, O60233, Q5T1U0	Gene names	CTSL2, CATL2, CTSU, CTSV
Domain Architecture
Description	Cathepsin L2 precursor (EC 3.4.22.43) (Cathepsin V) (Cathepsin U).