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Network neighborhood for query Sequence : PUR1_HUMAN

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PUR1_HUMAN
SwissProt Accessions	Q06203	Gene names	PPAT, GPAT
Domain Architecture
Description	Amidophosphoribosyltransferase precursor (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (GPAT).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PUR1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q06203	Gene names	PPAT, GPAT
Domain Architecture
Description	Amidophosphoribosyltransferase precursor (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (GPAT).

GFPT2_MOUSE
θ value	1.25267e-09 (rank : 2)	NC score	0.478230 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2Z9	Gene names	Gfpt2
Domain Architecture
Description	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (Hexosephosphate aminotransferase 2) (D-fructose-6- phosphate amidotransferase 2) (GFAT 2) (GFAT2).

GFPT2_HUMAN
θ value	2.13673e-09 (rank : 3)	NC score	0.476639 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	O94808, Q53XM2, Q9BWS4	Gene names	GFPT2
Domain Architecture
Description	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (Hexosephosphate aminotransferase 2) (D-fructose-6- phosphate amidotransferase 2) (GFAT 2) (GFAT2).

GFPT1_HUMAN
θ value	4.0297e-08 (rank : 4)	NC score	0.467057 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q06210, Q9BXF8	Gene names	GFPT1, GFAT, GFPT
Domain Architecture
Description	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (EC 2.6.1.16) (Hexosephosphate aminotransferase 1) (D-fructose-6- phosphate amidotransferase 1) (GFAT 1) (GFAT1).

GFPT1_MOUSE
θ value	1.17247e-07 (rank : 5)	NC score	0.463905 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P47856, Q91XG9, Q99LP7, Q99MJ4	Gene names	Gfpt1, Gfpt
Domain Architecture
Description	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (EC 2.6.1.16) (Hexosephosphate aminotransferase 1) (D-fructose-6- phosphate amidotransferase 1) (GFAT 1) (GFAT1).

HPRT_MOUSE
θ value	1.38821 (rank : 6)	NC score	0.079246 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	P00493, Q545Y2	Gene names	Hprt1, Hprt
Domain Architecture
Description	Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) (HGPRT) (HGPRTase) (HPRT B).

KI67_HUMAN
θ value	1.38821 (rank : 7)	NC score	0.042649 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	581	Shared Neighborhood Hits	2
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

HPRT_HUMAN
θ value	3.0926 (rank : 8)	NC score	0.070554 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	P00492	Gene names	HPRT1, HPRT
Domain Architecture
Description	Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) (HGPRT) (HGPRTase).

FOXD2_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.015848 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	143	Shared Neighborhood Hits	4
SwissProt Accessions	O60548	Gene names	FOXD2, FKHL17, FREAC9
Domain Architecture
Description	Forkhead box protein D2 (Forkhead-related protein FKHL17) (Forkhead- related transcription factor 9) (FREAC-9).

FOXD2_MOUSE
θ value	4.03905 (rank : 10)	NC score	0.015927 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	130	Shared Neighborhood Hits	4
SwissProt Accessions	O35392	Gene names	Foxd2, Mf2
Domain Architecture
Description	Forkhead box protein D2 (Mesoderm/mesenchyme forkhead 2) (MF-2).

NOS2A_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.018613 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P35228, O60757, O94994, Q16263, Q16692, Q4TTS5	Gene names	NOS2A, NOS2
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Hepatocyte NOS) (HEP- NOS).

BGLR_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.022138 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P08236, Q96CL9	Gene names	GUSB
Domain Architecture
Description	Beta-glucuronidase precursor (EC 3.2.1.31) (Beta-G1).

FOXD1_MOUSE
θ value	8.99809 (rank : 14)	NC score	0.013118 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q61345	Gene names	Foxd1, Fkhl8, Freac4, Hfhbf2
Domain Architecture
Description	Forkhead box protein D1 (Forkhead-related protein FKHL8) (Forkhead- related transcription factor 4) (FREAC-4) (Brain factor 2) (HFH-BF-2).

Hits sorted by NC score

PUR1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q06203	Gene names	PPAT, GPAT
Domain Architecture
Description	Amidophosphoribosyltransferase precursor (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (GPAT).

GFPT2_MOUSE
NC score	0.478230 (rank : 2)	θ value	1.25267e-09 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2Z9	Gene names	Gfpt2
Domain Architecture
Description	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (Hexosephosphate aminotransferase 2) (D-fructose-6- phosphate amidotransferase 2) (GFAT 2) (GFAT2).

GFPT2_HUMAN
NC score	0.476639 (rank : 3)	θ value	2.13673e-09 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	O94808, Q53XM2, Q9BWS4	Gene names	GFPT2
Domain Architecture
Description	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (Hexosephosphate aminotransferase 2) (D-fructose-6- phosphate amidotransferase 2) (GFAT 2) (GFAT2).

GFPT1_HUMAN
NC score	0.467057 (rank : 4)	θ value	4.0297e-08 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q06210, Q9BXF8	Gene names	GFPT1, GFAT, GFPT
Domain Architecture
Description	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (EC 2.6.1.16) (Hexosephosphate aminotransferase 1) (D-fructose-6- phosphate amidotransferase 1) (GFAT 1) (GFAT1).

GFPT1_MOUSE
NC score	0.463905 (rank : 5)	θ value	1.17247e-07 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P47856, Q91XG9, Q99LP7, Q99MJ4	Gene names	Gfpt1, Gfpt
Domain Architecture
Description	Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (EC 2.6.1.16) (Hexosephosphate aminotransferase 1) (D-fructose-6- phosphate amidotransferase 1) (GFAT 1) (GFAT1).

HPRT_MOUSE
NC score	0.079246 (rank : 6)	θ value	1.38821 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	P00493, Q545Y2	Gene names	Hprt1, Hprt
Domain Architecture
Description	Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) (HGPRT) (HGPRTase) (HPRT B).

HPRT_HUMAN
NC score	0.070554 (rank : 7)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	P00492	Gene names	HPRT1, HPRT
Domain Architecture
Description	Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) (HGPRT) (HGPRTase).

KI67_HUMAN
NC score	0.042649 (rank : 8)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	581	Shared Neighborhood Hits	2
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

BGLR_HUMAN
NC score	0.022138 (rank : 9)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P08236, Q96CL9	Gene names	GUSB
Domain Architecture
Description	Beta-glucuronidase precursor (EC 3.2.1.31) (Beta-G1).

NOS2A_HUMAN
NC score	0.018613 (rank : 10)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P35228, O60757, O94994, Q16263, Q16692, Q4TTS5	Gene names	NOS2A, NOS2
Domain Architecture
Description	Nitric oxide synthase, inducible (EC 1.14.13.39) (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS) (Hepatocyte NOS) (HEP- NOS).

FOXD2_MOUSE
NC score	0.015927 (rank : 11)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	130	Shared Neighborhood Hits	4
SwissProt Accessions	O35392	Gene names	Foxd2, Mf2
Domain Architecture
Description	Forkhead box protein D2 (Mesoderm/mesenchyme forkhead 2) (MF-2).

FOXD2_HUMAN
NC score	0.015848 (rank : 12)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	143	Shared Neighborhood Hits	4
SwissProt Accessions	O60548	Gene names	FOXD2, FKHL17, FREAC9
Domain Architecture
Description	Forkhead box protein D2 (Forkhead-related protein FKHL17) (Forkhead- related transcription factor 9) (FREAC-9).

FOXD1_MOUSE
NC score	0.013118 (rank : 13)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q61345	Gene names	Foxd1, Fkhl8, Freac4, Hfhbf2
Domain Architecture
Description	Forkhead box protein D1 (Forkhead-related protein FKHL8) (Forkhead- related transcription factor 4) (FREAC-4) (Brain factor 2) (HFH-BF-2).