Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : SESN1_MOUSE

For an explanation of this page, click here

Hits sorted by θ

SESN1_HUMAN
θ value	0 (rank : 1)	NC score	0.998820 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6P5, Q9NV00, Q9UPD5, Q9Y6P6	Gene names	SESN1, PA26, SEST1
Domain Architecture
Description	Sestrin-1 (p53-regulated protein PA26).

SESN3_HUMAN
θ value	1.46188e-167 (rank : 3)	NC score	0.989550 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P58005, Q96AD1	Gene names	SESN3, SEST3
Domain Architecture
Description	Sestrin-3.

SESN3_MOUSE
θ value	3.37019e-164 (rank : 4)	NC score	0.989826 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CYP7, Q3U2A0	Gene names	Sesn3, Sest3
Domain Architecture
Description	Sestrin-3.

SESN2_HUMAN
θ value	1.24331e-150 (rank : 5)	NC score	0.985152 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	P58004, Q96SI5	Gene names	SESN2, SEST2
Domain Architecture
Description	Sestrin-2 (Hi95).

SESN2_MOUSE
θ value	2.76981e-150 (rank : 6)	NC score	0.985545 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P58043	Gene names	Sesn2, Sest2
Domain Architecture
Description	Sestrin-2.

PDE9A_HUMAN
θ value	0.00134147 (rank : 7)	NC score	0.061199 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	O76083, O75490, O75491, O95225, Q86SF7, Q86SI6, Q86SJ3, Q86WN3, Q86WN4, Q86WN5, Q86WN6, Q86WN7, Q86WN8, Q86WN9, Q86WP0	Gene names	PDE9A
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

PDE9A_MOUSE
θ value	0.00390308 (rank : 8)	NC score	0.057115 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	O70628	Gene names	Pde9a, Pde8b
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

IQGA3_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.013852 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	Q86VI3	Gene names	IQGAP3
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP3.

MDM2_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.014357 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

Hits sorted by NC score

SESN1_HUMAN
NC score	0.998820 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6P5, Q9NV00, Q9UPD5, Q9Y6P6	Gene names	SESN1, PA26, SEST1
Domain Architecture
Description	Sestrin-1 (p53-regulated protein PA26).

SESN3_MOUSE
NC score	0.989826 (rank : 3)	θ value	3.37019e-164 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CYP7, Q3U2A0	Gene names	Sesn3, Sest3
Domain Architecture
Description	Sestrin-3.

SESN3_HUMAN
NC score	0.989550 (rank : 4)	θ value	1.46188e-167 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P58005, Q96AD1	Gene names	SESN3, SEST3
Domain Architecture
Description	Sestrin-3.

SESN2_MOUSE
NC score	0.985545 (rank : 5)	θ value	2.76981e-150 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P58043	Gene names	Sesn2, Sest2
Domain Architecture
Description	Sestrin-2.

SESN2_HUMAN
NC score	0.985152 (rank : 6)	θ value	1.24331e-150 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	P58004, Q96SI5	Gene names	SESN2, SEST2
Domain Architecture
Description	Sestrin-2 (Hi95).

PDE9A_HUMAN
NC score	0.061199 (rank : 7)	θ value	0.00134147 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	O76083, O75490, O75491, O95225, Q86SF7, Q86SI6, Q86SJ3, Q86WN3, Q86WN4, Q86WN5, Q86WN6, Q86WN7, Q86WN8, Q86WN9, Q86WP0	Gene names	PDE9A
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

PDE9A_MOUSE
NC score	0.057115 (rank : 8)	θ value	0.00390308 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	O70628	Gene names	Pde9a, Pde8b
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

MDM2_HUMAN
NC score	0.014357 (rank : 9)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	Q00987, Q13226, Q13297, Q13298, Q13299, Q13300, Q13301, Q53XW0, Q71TW9, Q9UGI3, Q9UMT8	Gene names	MDM2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).

IQGA3_HUMAN
NC score	0.013852 (rank : 10)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	Q86VI3	Gene names	IQGAP3
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP3.