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Network neighborhood for query Sequence : SESN2_HUMAN

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SESN2_HUMAN
SwissProt Accessions	P58004, Q96SI5	Gene names	SESN2, SEST2
Domain Architecture
Description	Sestrin-2 (Hi95).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SESN2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P58004, Q96SI5	Gene names	SESN2, SEST2
Domain Architecture
Description	Sestrin-2 (Hi95).

SESN2_MOUSE
θ value	0 (rank : 2)	NC score	0.998215 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	P58043	Gene names	Sesn2, Sest2
Domain Architecture
Description	Sestrin-2.

SESN1_HUMAN
θ value	1.12453e-151 (rank : 3)	NC score	0.985241 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6P5, Q9NV00, Q9UPD5, Q9Y6P6	Gene names	SESN1, PA26, SEST1
Domain Architecture
Description	Sestrin-1 (p53-regulated protein PA26).

SESN1_MOUSE
θ value	1.24331e-150 (rank : 4)	NC score	0.985152 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P58006, Q7TNF3	Gene names	Sesn1, Pa26, Sest1
Domain Architecture	No domain graphic available
Description	Sestrin-1 (p53-regulated protein PA26).

SESN3_HUMAN
θ value	8.33966e-147 (rank : 5)	NC score	0.987200 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P58005, Q96AD1	Gene names	SESN3, SEST3
Domain Architecture
Description	Sestrin-3.

SESN3_MOUSE
θ value	9.22056e-146 (rank : 6)	NC score	0.987743 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CYP7, Q3U2A0	Gene names	Sesn3, Sest3
Domain Architecture
Description	Sestrin-3.

PCNT_MOUSE
θ value	0.163984 (rank : 7)	NC score	0.016850 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	1207	Shared Neighborhood Hits	4
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

RYR2_HUMAN
θ value	1.06291 (rank : 8)	NC score	0.017594 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	175	Shared Neighborhood Hits	2
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

PKHA4_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.019313 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	283	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

CDA7L_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.016958 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q96GN5, Q6PIL4, Q86YT0, Q8IXN5, Q96C70, Q9H9A2, Q9NPV2	Gene names	CDCA7L, HR1, JPO2, R1
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2).

DC1L1_MOUSE
θ value	3.0926 (rank : 11)	NC score	0.014464 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1Q8	Gene names	Dync1li1, Dncli1, Dnclic1
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 1 (Dynein light intermediate chain 1, cytosolic) (Dynein light chain A) (DLC-A).

NALP5_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.007752 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	560	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

FRS3_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.008919 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

ZXDA_HUMAN
θ value	6.88961 (rank : 14)	NC score	-0.000560 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	750	Shared Neighborhood Hits	2
SwissProt Accessions	P98168, Q9UJP7	Gene names	ZXDA
Domain Architecture	No domain graphic available
Description	Zinc finger X-linked protein ZXDA.

TGBR3_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.008806 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q03167, Q5T2T4, Q5U731, Q9UGI2	Gene names	TGFBR3
Domain Architecture
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

Hits sorted by NC score

SESN2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P58004, Q96SI5	Gene names	SESN2, SEST2
Domain Architecture
Description	Sestrin-2 (Hi95).

SESN2_MOUSE
NC score	0.998215 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	P58043	Gene names	Sesn2, Sest2
Domain Architecture
Description	Sestrin-2.

SESN3_MOUSE
NC score	0.987743 (rank : 3)	θ value	9.22056e-146 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CYP7, Q3U2A0	Gene names	Sesn3, Sest3
Domain Architecture
Description	Sestrin-3.

SESN3_HUMAN
NC score	0.987200 (rank : 4)	θ value	8.33966e-147 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P58005, Q96AD1	Gene names	SESN3, SEST3
Domain Architecture
Description	Sestrin-3.

SESN1_HUMAN
NC score	0.985241 (rank : 5)	θ value	1.12453e-151 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6P5, Q9NV00, Q9UPD5, Q9Y6P6	Gene names	SESN1, PA26, SEST1
Domain Architecture
Description	Sestrin-1 (p53-regulated protein PA26).

SESN1_MOUSE
NC score	0.985152 (rank : 6)	θ value	1.24331e-150 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P58006, Q7TNF3	Gene names	Sesn1, Pa26, Sest1
Domain Architecture	No domain graphic available
Description	Sestrin-1 (p53-regulated protein PA26).

PKHA4_HUMAN
NC score	0.019313 (rank : 7)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	283	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

RYR2_HUMAN
NC score	0.017594 (rank : 8)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	175	Shared Neighborhood Hits	2
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

CDA7L_HUMAN
NC score	0.016958 (rank : 9)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q96GN5, Q6PIL4, Q86YT0, Q8IXN5, Q96C70, Q9H9A2, Q9NPV2	Gene names	CDCA7L, HR1, JPO2, R1
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2).

PCNT_MOUSE
NC score	0.016850 (rank : 10)	θ value	0.163984 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	1207	Shared Neighborhood Hits	4
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

DC1L1_MOUSE
NC score	0.014464 (rank : 11)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1Q8	Gene names	Dync1li1, Dncli1, Dnclic1
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 1 (Dynein light intermediate chain 1, cytosolic) (Dynein light chain A) (DLC-A).

FRS3_HUMAN
NC score	0.008919 (rank : 12)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

TGBR3_HUMAN
NC score	0.008806 (rank : 13)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q03167, Q5T2T4, Q5U731, Q9UGI2	Gene names	TGFBR3
Domain Architecture
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

NALP5_MOUSE
NC score	0.007752 (rank : 14)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	560	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

ZXDA_HUMAN
NC score	-0.000560 (rank : 15)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	750	Shared Neighborhood Hits	2
SwissProt Accessions	P98168, Q9UJP7	Gene names	ZXDA
Domain Architecture	No domain graphic available
Description	Zinc finger X-linked protein ZXDA.