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Network neighborhood for query Sequence : SESN3_HUMAN

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SESN3_HUMAN
SwissProt Accessions	P58005, Q96AD1	Gene names	SESN3, SEST3
Domain Architecture
Description	Sestrin-3.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SESN3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P58005, Q96AD1	Gene names	SESN3, SEST3
Domain Architecture
Description	Sestrin-3.

SESN3_MOUSE
θ value	0 (rank : 2)	NC score	0.999402 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CYP7, Q3U2A0	Gene names	Sesn3, Sest3
Domain Architecture
Description	Sestrin-3.

SESN1_HUMAN
θ value	7.7336e-177 (rank : 3)	NC score	0.990324 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6P5, Q9NV00, Q9UPD5, Q9Y6P6	Gene names	SESN1, PA26, SEST1
Domain Architecture
Description	Sestrin-1 (p53-regulated protein PA26).

SESN1_MOUSE
θ value	1.46188e-167 (rank : 4)	NC score	0.989550 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P58006, Q7TNF3	Gene names	Sesn1, Pa26, Sest1
Domain Architecture	No domain graphic available
Description	Sestrin-1 (p53-regulated protein PA26).

SESN2_MOUSE
θ value	4.42207e-148 (rank : 5)	NC score	0.987673 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P58043	Gene names	Sesn2, Sest2
Domain Architecture
Description	Sestrin-2.

SESN2_HUMAN
θ value	8.33966e-147 (rank : 6)	NC score	0.987200 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	P58004, Q96SI5	Gene names	SESN2, SEST2
Domain Architecture
Description	Sestrin-2 (Hi95).

MYH11_HUMAN
θ value	1.81305 (rank : 7)	NC score	0.004945 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	1806	Shared Neighborhood Hits	5
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	1.81305 (rank : 8)	NC score	0.005053 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	1777	Shared Neighborhood Hits	5
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

LIPA4_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.015863 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	O75335, O94971	Gene names	PPFIA4, KIAA0897
Domain Architecture
Description	Liprin-alpha-4 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4) (PTPRF-interacting protein alpha-4).

CC023_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.017691 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q66JZ4	Gene names	D9Ertd402e
Domain Architecture	No domain graphic available
Description	Protein C3orf23 homolog.

GOGA5_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.002164 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	1434	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

KAD2_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.010299 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P54819, Q16856, Q5TIF7, Q8TCY2, Q8TCY3	Gene names	AK2, ADK2
Domain Architecture
Description	Adenylate kinase isoenzyme 2, mitochondrial (EC 2.7.4.3) (ATP-AMP transphosphorylase).

KAD2_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.010370 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTP6, Q3TKI6, Q9CY37	Gene names	Ak2, Ak-2
Domain Architecture
Description	Adenylate kinase isoenzyme 2, mitochondrial (EC 2.7.4.3) (ATP-AMP transphosphorylase).

MRCKA_HUMAN
θ value	8.99809 (rank : 14)	NC score	-0.000408 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	1999	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

Hits sorted by NC score

SESN3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P58005, Q96AD1	Gene names	SESN3, SEST3
Domain Architecture
Description	Sestrin-3.

SESN3_MOUSE
NC score	0.999402 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CYP7, Q3U2A0	Gene names	Sesn3, Sest3
Domain Architecture
Description	Sestrin-3.

SESN1_HUMAN
NC score	0.990324 (rank : 3)	θ value	7.7336e-177 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6P5, Q9NV00, Q9UPD5, Q9Y6P6	Gene names	SESN1, PA26, SEST1
Domain Architecture
Description	Sestrin-1 (p53-regulated protein PA26).

SESN1_MOUSE
NC score	0.989550 (rank : 4)	θ value	1.46188e-167 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P58006, Q7TNF3	Gene names	Sesn1, Pa26, Sest1
Domain Architecture	No domain graphic available
Description	Sestrin-1 (p53-regulated protein PA26).

SESN2_MOUSE
NC score	0.987673 (rank : 5)	θ value	4.42207e-148 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P58043	Gene names	Sesn2, Sest2
Domain Architecture
Description	Sestrin-2.

SESN2_HUMAN
NC score	0.987200 (rank : 6)	θ value	8.33966e-147 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	P58004, Q96SI5	Gene names	SESN2, SEST2
Domain Architecture
Description	Sestrin-2 (Hi95).

CC023_MOUSE
NC score	0.017691 (rank : 7)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q66JZ4	Gene names	D9Ertd402e
Domain Architecture	No domain graphic available
Description	Protein C3orf23 homolog.

LIPA4_HUMAN
NC score	0.015863 (rank : 8)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	O75335, O94971	Gene names	PPFIA4, KIAA0897
Domain Architecture
Description	Liprin-alpha-4 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4) (PTPRF-interacting protein alpha-4).

KAD2_MOUSE
NC score	0.010370 (rank : 9)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTP6, Q3TKI6, Q9CY37	Gene names	Ak2, Ak-2
Domain Architecture
Description	Adenylate kinase isoenzyme 2, mitochondrial (EC 2.7.4.3) (ATP-AMP transphosphorylase).

KAD2_HUMAN
NC score	0.010299 (rank : 10)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P54819, Q16856, Q5TIF7, Q8TCY2, Q8TCY3	Gene names	AK2, ADK2
Domain Architecture
Description	Adenylate kinase isoenzyme 2, mitochondrial (EC 2.7.4.3) (ATP-AMP transphosphorylase).

MYH11_MOUSE
NC score	0.005053 (rank : 11)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	1777	Shared Neighborhood Hits	5
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_HUMAN
NC score	0.004945 (rank : 12)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	1806	Shared Neighborhood Hits	5
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

GOGA5_MOUSE
NC score	0.002164 (rank : 13)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	1434	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

MRCKA_HUMAN
NC score	-0.000408 (rank : 14)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	1999	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).