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Network neighborhood for query Sequence : REV1_HUMAN

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REV1_HUMAN
SwissProt Accessions	Q9UBZ9, O95941, Q9C0J4, Q9NUP2	Gene names	REV1L, REV1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase) (Alpha integrin-binding protein 80) (AIBP80).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

REV1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UBZ9, O95941, Q9C0J4, Q9NUP2	Gene names	REV1L, REV1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase) (Alpha integrin-binding protein 80) (AIBP80).

REV1_MOUSE
θ value	0 (rank : 2)	NC score	0.980203 (rank : 2)
Query Neighborhood Hits	56	Target Neighborhood Hits	67	Shared Neighborhood Hits	16
SwissProt Accessions	Q920Q2, Q9QXV2	Gene names	Rev1l, Rev1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase).

POLK_MOUSE
θ value	2.43343e-21 (rank : 3)	NC score	0.600833 (rank : 3)
Query Neighborhood Hits	56	Target Neighborhood Hits	66	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QUG2, Q7TPY7	Gene names	Polk, Dinb1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

POLK_HUMAN
θ value	5.99374e-20 (rank : 4)	NC score	0.580511 (rank : 5)
Query Neighborhood Hits	56	Target Neighborhood Hits	64	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UBT6, Q86VJ8, Q8IZY0, Q8IZY1, Q8NB30, Q96L01, Q96Q86, Q96Q87, Q9UHC5	Gene names	POLK, DINB1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

POLI_HUMAN
θ value	7.32683e-18 (rank : 5)	NC score	0.584871 (rank : 4)
Query Neighborhood Hits	56	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UNA4, Q8N590, Q9H0S1, Q9NYH6	Gene names	POLI, RAD30B
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (RAD30 homolog B) (Eta2).

POLI_MOUSE
θ value	9.56915e-18 (rank : 6)	NC score	0.579068 (rank : 6)
Query Neighborhood Hits	56	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	Q6R3M4, Q641P1, Q6R3M3, Q9R1A6	Gene names	Poli, Rad30b
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B).

POLH_MOUSE
θ value	5.62301e-10 (rank : 7)	NC score	0.491064 (rank : 7)
Query Neighborhood Hits	56	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JJN0, Q9JJJ2	Gene names	Polh, Rad30a, Xpv
Domain Architecture	No domain graphic available
Description	DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein homolog).

POLH_HUMAN
θ value	2.13673e-09 (rank : 8)	NC score	0.477741 (rank : 8)
Query Neighborhood Hits	56	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y253, Q7L8E3, Q96BC4, Q9BX13	Gene names	POLH, RAD30, RAD30A, XPV
Domain Architecture	No domain graphic available
Description	DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein).

KCNQ5_HUMAN
θ value	0.0330416 (rank : 9)	NC score	0.032328 (rank : 14)
Query Neighborhood Hits	56	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

TOPB1_HUMAN
θ value	0.0330416 (rank : 10)	NC score	0.109051 (rank : 9)
Query Neighborhood Hits	56	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q92547, Q7LGC1, Q9UEB9	Gene names	TOPBP1, KIAA0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-binding protein 1) (DNA topoisomerase IIbeta-binding protein 1) (TopBP1).

HUWE1_MOUSE
θ value	0.21417 (rank : 11)	NC score	0.052292 (rank : 12)
Query Neighborhood Hits	56	Target Neighborhood Hits	406	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

PDK1L_MOUSE
θ value	0.279714 (rank : 12)	NC score	0.011952 (rank : 44)
Query Neighborhood Hits	56	Target Neighborhood Hits	821	Shared Neighborhood Hits	3
SwissProt Accessions	Q8QZR7, Q3URF0, Q8BKB3	Gene names	Pdik1l
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1- interacting kinase 1-like).

UBP28_MOUSE
θ value	0.279714 (rank : 13)	NC score	0.029931 (rank : 17)
Query Neighborhood Hits	56	Target Neighborhood Hits	178	Shared Neighborhood Hits	3
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

HUWE1_HUMAN
θ value	0.365318 (rank : 14)	NC score	0.050559 (rank : 13)
Query Neighborhood Hits	56	Target Neighborhood Hits	443	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

PDK1L_HUMAN
θ value	0.365318 (rank : 15)	NC score	0.011666 (rank : 45)
Query Neighborhood Hits	56	Target Neighborhood Hits	821	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N165, Q5T2I0, Q8NDB3	Gene names	PDIK1L, CLIK1L
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1- interacting kinase 1-like).

LRCH2_HUMAN
θ value	1.06291 (rank : 16)	NC score	0.017205 (rank : 27)
Query Neighborhood Hits	56	Target Neighborhood Hits	315	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

MAP1B_MOUSE
θ value	1.06291 (rank : 17)	NC score	0.027413 (rank : 19)
Query Neighborhood Hits	56	Target Neighborhood Hits	977	Shared Neighborhood Hits	17
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

TOPB1_MOUSE
θ value	1.38821 (rank : 18)	NC score	0.074898 (rank : 10)
Query Neighborhood Hits	56	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

NCOA7_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.023950 (rank : 22)
Query Neighborhood Hits	56	Target Neighborhood Hits	160	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NI08, Q3LID6, Q4G0V1, Q5TF95, Q6IPQ4, Q6NE83, Q86T89, Q8N1W4	Gene names	NCOA7, ERAP140, ESNA1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1).

ENAM_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.026335 (rank : 20)
Query Neighborhood Hits	56	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

FOXO1_MOUSE
θ value	2.36792 (rank : 21)	NC score	0.017317 (rank : 26)
Query Neighborhood Hits	56	Target Neighborhood Hits	118	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R1E0	Gene names	Foxo1a, Fkhr, Foxo1
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

MUC1_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.016378 (rank : 29)
Query Neighborhood Hits	56	Target Neighborhood Hits	975	Shared Neighborhood Hits	12
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

HRX_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.018959 (rank : 24)
Query Neighborhood Hits	56	Target Neighborhood Hits	825	Shared Neighborhood Hits	13
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SH3K1_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.015024 (rank : 36)
Query Neighborhood Hits	56	Target Neighborhood Hits	332	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

TAI12_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.030764 (rank : 16)
Query Neighborhood Hits	56	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H175	Gene names	TAIP12, C12orf22
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

TAI12_MOUSE
θ value	3.0926 (rank : 26)	NC score	0.031000 (rank : 15)
Query Neighborhood Hits	56	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGQ2, Q3UIH1	Gene names	Taip12
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

CCD22_MOUSE
θ value	4.03905 (rank : 27)	NC score	0.016864 (rank : 28)
Query Neighborhood Hits	56	Target Neighborhood Hits	268	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIG7, Q8BYH4	Gene names	Ccdc22, DXImx40e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

CD2AP_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.013930 (rank : 39)
Query Neighborhood Hits	56	Target Neighborhood Hits	315	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

DPOLZ_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.015470 (rank : 34)
Query Neighborhood Hits	56	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

MAP1B_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.023646 (rank : 23)
Query Neighborhood Hits	56	Target Neighborhood Hits	903	Shared Neighborhood Hits	12
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

SYNE2_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.007098 (rank : 52)
Query Neighborhood Hits	56	Target Neighborhood Hits	1323	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

CO4A1_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.006875 (rank : 53)
Query Neighborhood Hits	56	Target Neighborhood Hits	450	Shared Neighborhood Hits	8
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

FOXO1_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.014656 (rank : 38)
Query Neighborhood Hits	56	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q12778, O43523, Q5VYC7, Q6NSK6	Gene names	FOXO1A, FKHR
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

SYBU_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.015668 (rank : 33)
Query Neighborhood Hits	56	Target Neighborhood Hits	188	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NX95, Q5R1T1, Q5R1T2, Q5R1T3, Q5Y2M6, Q8ND49, Q8TCR6, Q9P256	Gene names	SYBU, GOLSYN, KIAA1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein).

TAIP2_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.025320 (rank : 21)
Query Neighborhood Hits	56	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	P59055	Gene names	Taip2
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 2 (TAIP-2).

UTRO_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.006025 (rank : 54)
Query Neighborhood Hits	56	Target Neighborhood Hits	960	Shared Neighborhood Hits	6
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

CSKI2_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.005614 (rank : 55)
Query Neighborhood Hits	56	Target Neighborhood Hits	747	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

GTSE1_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.016181 (rank : 31)
Query Neighborhood Hits	56	Target Neighborhood Hits	245	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

K0240_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.014694 (rank : 37)
Query Neighborhood Hits	56	Target Neighborhood Hits	211	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

KIRR3_MOUSE
θ value	6.88961 (rank : 40)	NC score	0.009764 (rank : 48)
Query Neighborhood Hits	56	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

LRCH2_MOUSE
θ value	6.88961 (rank : 41)	NC score	0.012567 (rank : 42)
Query Neighborhood Hits	56	Target Neighborhood Hits	287	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

MEIS3_MOUSE
θ value	6.88961 (rank : 42)	NC score	0.007525 (rank : 51)
Query Neighborhood Hits	56	Target Neighborhood Hits	118	Shared Neighborhood Hits	2
SwissProt Accessions	P97368, Q99L81	Gene names	Meis3, Mrg2
Domain Architecture
Description	Homeobox protein Meis3 (Meis1-related protein 2).

NBN_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.016307 (rank : 30)
Query Neighborhood Hits	56	Target Neighborhood Hits	226	Shared Neighborhood Hits	6
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

NFH_MOUSE
θ value	6.88961 (rank : 44)	NC score	0.004998 (rank : 56)
Query Neighborhood Hits	56	Target Neighborhood Hits	2247	Shared Neighborhood Hits	20
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NPAS4_MOUSE
θ value	6.88961 (rank : 45)	NC score	0.015838 (rank : 32)
Query Neighborhood Hits	56	Target Neighborhood Hits	245	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

NU133_MOUSE
θ value	6.88961 (rank : 46)	NC score	0.028127 (rank : 18)
Query Neighborhood Hits	56	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0G9	Gene names	Nup133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

PA24A_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.012682 (rank : 41)
Query Neighborhood Hits	56	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PHLB1_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.015237 (rank : 35)
Query Neighborhood Hits	56	Target Neighborhood Hits	1038	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SGIP1_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.017913 (rank : 25)
Query Neighborhood Hits	56	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

CN145_MOUSE
θ value	8.99809 (rank : 50)	NC score	0.004293 (rank : 57)
Query Neighborhood Hits	56	Target Neighborhood Hits	916	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

LR37A_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.009070 (rank : 49)
Query Neighborhood Hits	56	Target Neighborhood Hits	720	Shared Neighborhood Hits	15
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

NDUS1_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.012428 (rank : 43)
Query Neighborhood Hits	56	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P28331, Q53TR8, Q8N1C4, Q8TCC9	Gene names	NDUFS1
Domain Architecture
Description	NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-75kD) (CI-75kD).

NPAS4_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.013884 (rank : 40)
Query Neighborhood Hits	56	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

PA24A_MOUSE
θ value	8.99809 (rank : 54)	NC score	0.011657 (rank : 46)
Query Neighborhood Hits	56	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PKHA5_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.008727 (rank : 50)
Query Neighborhood Hits	56	Target Neighborhood Hits	455	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

TENS1_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.010940 (rank : 47)
Query Neighborhood Hits	56	Target Neighborhood Hits	400	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

XRCC1_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.057451 (rank : 11)
Query Neighborhood Hits	56	Target Neighborhood Hits	131	Shared Neighborhood Hits	6
SwissProt Accessions	P18887, Q9HCB1	Gene names	XRCC1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

Hits sorted by NC score

REV1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UBZ9, O95941, Q9C0J4, Q9NUP2	Gene names	REV1L, REV1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase) (Alpha integrin-binding protein 80) (AIBP80).

REV1_MOUSE
NC score	0.980203 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	56	Target Neighborhood Hits	67	Shared Neighborhood Hits	16
SwissProt Accessions	Q920Q2, Q9QXV2	Gene names	Rev1l, Rev1
Domain Architecture	No domain graphic available
Description	DNA repair protein REV1 (EC 2.7.7.-) (Rev1-like terminal deoxycytidyl transferase).

POLK_MOUSE
NC score	0.600833 (rank : 3)	θ value	2.43343e-21 (rank : 3)
Query Neighborhood Hits	56	Target Neighborhood Hits	66	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QUG2, Q7TPY7	Gene names	Polk, Dinb1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

POLI_HUMAN
NC score	0.584871 (rank : 4)	θ value	7.32683e-18 (rank : 5)
Query Neighborhood Hits	56	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UNA4, Q8N590, Q9H0S1, Q9NYH6	Gene names	POLI, RAD30B
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (RAD30 homolog B) (Eta2).

POLK_HUMAN
NC score	0.580511 (rank : 5)	θ value	5.99374e-20 (rank : 4)
Query Neighborhood Hits	56	Target Neighborhood Hits	64	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UBT6, Q86VJ8, Q8IZY0, Q8IZY1, Q8NB30, Q96L01, Q96Q86, Q96Q87, Q9UHC5	Gene names	POLK, DINB1
Domain Architecture	No domain graphic available
Description	DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP).

POLI_MOUSE
NC score	0.579068 (rank : 6)	θ value	9.56915e-18 (rank : 6)
Query Neighborhood Hits	56	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	Q6R3M4, Q641P1, Q6R3M3, Q9R1A6	Gene names	Poli, Rad30b
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B).

POLH_MOUSE
NC score	0.491064 (rank : 7)	θ value	5.62301e-10 (rank : 7)
Query Neighborhood Hits	56	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JJN0, Q9JJJ2	Gene names	Polh, Rad30a, Xpv
Domain Architecture	No domain graphic available
Description	DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein homolog).

POLH_HUMAN
NC score	0.477741 (rank : 8)	θ value	2.13673e-09 (rank : 8)
Query Neighborhood Hits	56	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y253, Q7L8E3, Q96BC4, Q9BX13	Gene names	POLH, RAD30, RAD30A, XPV
Domain Architecture	No domain graphic available
Description	DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein).

TOPB1_HUMAN
NC score	0.109051 (rank : 9)	θ value	0.0330416 (rank : 10)
Query Neighborhood Hits	56	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q92547, Q7LGC1, Q9UEB9	Gene names	TOPBP1, KIAA0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-binding protein 1) (DNA topoisomerase IIbeta-binding protein 1) (TopBP1).

TOPB1_MOUSE
NC score	0.074898 (rank : 10)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	56	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

XRCC1_HUMAN
NC score	0.057451 (rank : 11)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	56	Target Neighborhood Hits	131	Shared Neighborhood Hits	6
SwissProt Accessions	P18887, Q9HCB1	Gene names	XRCC1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

HUWE1_MOUSE
NC score	0.052292 (rank : 12)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	56	Target Neighborhood Hits	406	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HUWE1_HUMAN
NC score	0.050559 (rank : 13)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	56	Target Neighborhood Hits	443	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

KCNQ5_HUMAN
NC score	0.032328 (rank : 14)	θ value	0.0330416 (rank : 9)
Query Neighborhood Hits	56	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

TAI12_MOUSE
NC score	0.031000 (rank : 15)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	56	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGQ2, Q3UIH1	Gene names	Taip12
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

TAI12_HUMAN
NC score	0.030764 (rank : 16)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	56	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H175	Gene names	TAIP12, C12orf22
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

UBP28_MOUSE
NC score	0.029931 (rank : 17)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	56	Target Neighborhood Hits	178	Shared Neighborhood Hits	3
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

NU133_MOUSE
NC score	0.028127 (rank : 18)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	56	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0G9	Gene names	Nup133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

MAP1B_MOUSE
NC score	0.027413 (rank : 19)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	56	Target Neighborhood Hits	977	Shared Neighborhood Hits	17
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

ENAM_HUMAN
NC score	0.026335 (rank : 20)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	56	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

TAIP2_MOUSE
NC score	0.025320 (rank : 21)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	56	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	P59055	Gene names	Taip2
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 2 (TAIP-2).

NCOA7_HUMAN
NC score	0.023950 (rank : 22)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	56	Target Neighborhood Hits	160	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NI08, Q3LID6, Q4G0V1, Q5TF95, Q6IPQ4, Q6NE83, Q86T89, Q8N1W4	Gene names	NCOA7, ERAP140, ESNA1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1).

MAP1B_HUMAN
NC score	0.023646 (rank : 23)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	56	Target Neighborhood Hits	903	Shared Neighborhood Hits	12
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

HRX_HUMAN
NC score	0.018959 (rank : 24)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	56	Target Neighborhood Hits	825	Shared Neighborhood Hits	13
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SGIP1_HUMAN
NC score	0.017913 (rank : 25)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	56	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

FOXO1_MOUSE
NC score	0.017317 (rank : 26)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	56	Target Neighborhood Hits	118	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R1E0	Gene names	Foxo1a, Fkhr, Foxo1
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

LRCH2_HUMAN
NC score	0.017205 (rank : 27)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	56	Target Neighborhood Hits	315	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

CCD22_MOUSE
NC score	0.016864 (rank : 28)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	56	Target Neighborhood Hits	268	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIG7, Q8BYH4	Gene names	Ccdc22, DXImx40e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

MUC1_HUMAN
NC score	0.016378 (rank : 29)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	56	Target Neighborhood Hits	975	Shared Neighborhood Hits	12
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NBN_HUMAN
NC score	0.016307 (rank : 30)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	56	Target Neighborhood Hits	226	Shared Neighborhood Hits	6
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

GTSE1_MOUSE
NC score	0.016181 (rank : 31)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	56	Target Neighborhood Hits	245	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

NPAS4_MOUSE
NC score	0.015838 (rank : 32)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	56	Target Neighborhood Hits	245	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

SYBU_HUMAN
NC score	0.015668 (rank : 33)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	56	Target Neighborhood Hits	188	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NX95, Q5R1T1, Q5R1T2, Q5R1T3, Q5Y2M6, Q8ND49, Q8TCR6, Q9P256	Gene names	SYBU, GOLSYN, KIAA1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein).

DPOLZ_HUMAN
NC score	0.015470 (rank : 34)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	56	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

PHLB1_HUMAN
NC score	0.015237 (rank : 35)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	56	Target Neighborhood Hits	1038	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SH3K1_MOUSE
NC score	0.015024 (rank : 36)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	56	Target Neighborhood Hits	332	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

K0240_MOUSE
NC score	0.014694 (rank : 37)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	56	Target Neighborhood Hits	211	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

FOXO1_HUMAN
NC score	0.014656 (rank : 38)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	56	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q12778, O43523, Q5VYC7, Q6NSK6	Gene names	FOXO1A, FKHR
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

CD2AP_HUMAN
NC score	0.013930 (rank : 39)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	56	Target Neighborhood Hits	315	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

NPAS4_HUMAN
NC score	0.013884 (rank : 40)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	56	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

PA24A_HUMAN
NC score	0.012682 (rank : 41)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	56	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

LRCH2_MOUSE
NC score	0.012567 (rank : 42)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	56	Target Neighborhood Hits	287	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

NDUS1_HUMAN
NC score	0.012428 (rank : 43)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	56	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P28331, Q53TR8, Q8N1C4, Q8TCC9	Gene names	NDUFS1
Domain Architecture
Description	NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-75kD) (CI-75kD).

PDK1L_MOUSE
NC score	0.011952 (rank : 44)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	56	Target Neighborhood Hits	821	Shared Neighborhood Hits	3
SwissProt Accessions	Q8QZR7, Q3URF0, Q8BKB3	Gene names	Pdik1l
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1- interacting kinase 1-like).

PDK1L_HUMAN
NC score	0.011666 (rank : 45)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	56	Target Neighborhood Hits	821	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N165, Q5T2I0, Q8NDB3	Gene names	PDIK1L, CLIK1L
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1- interacting kinase 1-like).

PA24A_MOUSE
NC score	0.011657 (rank : 46)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	56	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

TENS1_HUMAN
NC score	0.010940 (rank : 47)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	56	Target Neighborhood Hits	400	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

KIRR3_MOUSE
NC score	0.009764 (rank : 48)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	56	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

LR37A_HUMAN
NC score	0.009070 (rank : 49)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	56	Target Neighborhood Hits	720	Shared Neighborhood Hits	15
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

PKHA5_HUMAN
NC score	0.008727 (rank : 50)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	56	Target Neighborhood Hits	455	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

MEIS3_MOUSE
NC score	0.007525 (rank : 51)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	56	Target Neighborhood Hits	118	Shared Neighborhood Hits	2
SwissProt Accessions	P97368, Q99L81	Gene names	Meis3, Mrg2
Domain Architecture
Description	Homeobox protein Meis3 (Meis1-related protein 2).

SYNE2_HUMAN
NC score	0.007098 (rank : 52)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	56	Target Neighborhood Hits	1323	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

CO4A1_MOUSE
NC score	0.006875 (rank : 53)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	56	Target Neighborhood Hits	450	Shared Neighborhood Hits	8
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

UTRO_HUMAN
NC score	0.006025 (rank : 54)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	56	Target Neighborhood Hits	960	Shared Neighborhood Hits	6
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

CSKI2_HUMAN
NC score	0.005614 (rank : 55)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	56	Target Neighborhood Hits	747	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

NFH_MOUSE
NC score	0.004998 (rank : 56)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	56	Target Neighborhood Hits	2247	Shared Neighborhood Hits	20
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CN145_MOUSE
NC score	0.004293 (rank : 57)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	56	Target Neighborhood Hits	916	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.