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Network neighborhood for query Sequence : SYEP_HUMAN

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SYEP_HUMAN
SwissProt Accessions	P07814	Gene names	EPRS, GLNS, PARS, QPRS
Domain Architecture
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SYEP_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	70	Target Neighborhood Hits	70	Shared Neighborhood Hits	70
SwissProt Accessions	P07814	Gene names	EPRS, GLNS, PARS, QPRS
Domain Architecture
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

SYEP_MOUSE
θ value	0 (rank : 2)	NC score	0.965214 (rank : 2)
Query Neighborhood Hits	70	Target Neighborhood Hits	123	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CGC7	Gene names	Eprs, Qprs
Domain Architecture	No domain graphic available
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

SYQ_HUMAN
θ value	8.53533e-67 (rank : 3)	NC score	0.799268 (rank : 3)
Query Neighborhood Hits	70	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P47897	Gene names	QARS
Domain Architecture
Description	Glutaminyl-tRNA synthetase (EC 6.1.1.18) (Glutamine--tRNA ligase) (GlnRS).

SYW_MOUSE
θ value	2.0648e-12 (rank : 4)	NC score	0.404288 (rank : 4)
Query Neighborhood Hits	70	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P32921, Q80ZY4, Q99J58, Q9DC65	Gene names	Wars, Wrs
Domain Architecture
Description	Tryptophanyl-tRNA synthetase (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS).

SYW_HUMAN
θ value	1.25267e-09 (rank : 5)	NC score	0.370530 (rank : 5)
Query Neighborhood Hits	70	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P23381, P78535, Q9UDL3	Gene names	WARS, WRS
Domain Architecture
Description	Tryptophanyl-tRNA synthetase (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS) (IFP53) (hWRS).

SYM_HUMAN
θ value	5.44631e-05 (rank : 6)	NC score	0.213020 (rank : 7)
Query Neighborhood Hits	70	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	P56192, Q14895, Q53H14, Q96A15, Q96BZ0, Q9NSE0	Gene names	MARS
Domain Architecture
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

SYG_MOUSE
θ value	0.00102713 (rank : 7)	NC score	0.165709 (rank : 10)
Query Neighborhood Hits	70	Target Neighborhood Hits	27	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CZD3, Q8VC67	Gene names	Gars
Domain Architecture
Description	Glycyl-tRNA synthetase (EC 6.1.1.14) (Glycine--tRNA ligase) (GlyRS).

SYM_MOUSE
θ value	0.00102713 (rank : 8)	NC score	0.191728 (rank : 9)
Query Neighborhood Hits	70	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q68FL6	Gene names	Mars
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

MCA3_MOUSE
θ value	0.00665767 (rank : 9)	NC score	0.226003 (rank : 6)
Query Neighborhood Hits	70	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D1M4	Gene names	Eef1e1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation elongation factor 1 epsilon-1 (Multisynthetase complex auxiliary component p18) (Elongation factor p18).

PTPRZ_HUMAN
θ value	0.0252991 (rank : 10)	NC score	0.032002 (rank : 33)
Query Neighborhood Hits	70	Target Neighborhood Hits	255	Shared Neighborhood Hits	7
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

SYTC_HUMAN
θ value	0.0563607 (rank : 11)	NC score	0.087674 (rank : 15)
Query Neighborhood Hits	70	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	P26639, Q96FP5, Q9BWA6	Gene names	TARS
Domain Architecture
Description	Threonyl-tRNA synthetase, cytoplasmic (EC 6.1.1.3) (Threonine--tRNA ligase) (ThrRS).

SYTC_MOUSE
θ value	0.0563607 (rank : 12)	NC score	0.087605 (rank : 16)
Query Neighborhood Hits	70	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D0R2, Q3TL42, Q7TMQ2, Q8BMI6, Q9CX03	Gene names	Tars
Domain Architecture	No domain graphic available
Description	Threonyl-tRNA synthetase, cytoplasmic (EC 6.1.1.3) (Threonine--tRNA ligase) (ThrRS).

MCA3_HUMAN
θ value	0.0961366 (rank : 13)	NC score	0.206086 (rank : 8)
Query Neighborhood Hits	70	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	O43324, Q5THS2	Gene names	EEF1E1
Domain Architecture
Description	Eukaryotic translation elongation factor 1 epsilon-1 (Multisynthetase complex auxiliary component p18) (Elongation factor p18).

RRBP1_HUMAN
θ value	0.0961366 (rank : 14)	NC score	0.040605 (rank : 27)
Query Neighborhood Hits	70	Target Neighborhood Hits	1306	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

SYG_HUMAN
θ value	0.0961366 (rank : 15)	NC score	0.147897 (rank : 11)
Query Neighborhood Hits	70	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	P41250, Q969Y1	Gene names	GARS
Domain Architecture
Description	Glycyl-tRNA synthetase (EC 6.1.1.14) (Glycine--tRNA ligase) (GlyRS).

SYPM_MOUSE
θ value	0.0961366 (rank : 16)	NC score	0.115314 (rank : 13)
Query Neighborhood Hits	70	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CFI5, Q8R0C4	Gene names	Pars2
Domain Architecture	No domain graphic available
Description	Probable prolyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.15) (Proline--tRNA ligase) (ProRS).

ZN217_HUMAN
θ value	0.125558 (rank : 17)	NC score	0.009921 (rank : 67)
Query Neighborhood Hits	70	Target Neighborhood Hits	905	Shared Neighborhood Hits	5
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

RRBP1_MOUSE
θ value	0.163984 (rank : 18)	NC score	0.033558 (rank : 32)
Query Neighborhood Hits	70	Target Neighborhood Hits	1650	Shared Neighborhood Hits	26
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SYPM_HUMAN
θ value	0.163984 (rank : 19)	NC score	0.089815 (rank : 14)
Query Neighborhood Hits	70	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	Q7L3T8, Q9H6S5, Q9UFT1	Gene names	PARS2
Domain Architecture	No domain graphic available
Description	Probable prolyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.15) (Proline--tRNA ligase) (ProRS).

MCA2_HUMAN
θ value	0.21417 (rank : 20)	NC score	0.135605 (rank : 12)
Query Neighborhood Hits	70	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q13155, Q96CZ5, Q9P1L2	Gene names	JTV1
Domain Architecture
Description	Multisynthetase complex auxiliary component p38 (Protein JTV-1).

GP155_HUMAN
θ value	0.279714 (rank : 21)	NC score	0.071812 (rank : 20)
Query Neighborhood Hits	70	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

LAMA2_MOUSE
θ value	0.279714 (rank : 22)	NC score	0.018554 (rank : 44)
Query Neighborhood Hits	70	Target Neighborhood Hits	1198	Shared Neighborhood Hits	17
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

SYH_MOUSE
θ value	0.279714 (rank : 23)	NC score	0.083006 (rank : 17)
Query Neighborhood Hits	70	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q61035	Gene names	Hars
Domain Architecture
Description	Histidyl-tRNA synthetase (EC 6.1.1.21) (Histidine--tRNA ligase) (HisRS).

NCF2_HUMAN
θ value	0.365318 (rank : 24)	NC score	0.053010 (rank : 21)
Query Neighborhood Hits	70	Target Neighborhood Hits	229	Shared Neighborhood Hits	6
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

CN145_HUMAN
θ value	0.813845 (rank : 25)	NC score	0.018772 (rank : 41)
Query Neighborhood Hits	70	Target Neighborhood Hits	1196	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

SYH_HUMAN
θ value	0.813845 (rank : 26)	NC score	0.080436 (rank : 18)
Query Neighborhood Hits	70	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	P12081	Gene names	HARS, HRS
Domain Architecture
Description	Histidyl-tRNA synthetase (EC 6.1.1.21) (Histidine--tRNA ligase) (HisRS).

CD2AP_MOUSE
θ value	1.38821 (rank : 27)	NC score	0.044815 (rank : 26)
Query Neighborhood Hits	70	Target Neighborhood Hits	336	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

ESCO1_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.035430 (rank : 30)
Query Neighborhood Hits	70	Target Neighborhood Hits	361	Shared Neighborhood Hits	15
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

SRBS1_MOUSE
θ value	1.38821 (rank : 29)	NC score	0.023995 (rank : 39)
Query Neighborhood Hits	70	Target Neighborhood Hits	409	Shared Neighborhood Hits	12
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SYCC_MOUSE
θ value	1.81305 (rank : 30)	NC score	0.046042 (rank : 25)
Query Neighborhood Hits	70	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ER72, O88303, Q8BP81, Q8CAY7, Q8CCE3, Q8K0S4, Q9ER68	Gene names	Cars
Domain Architecture
Description	Cysteinyl-tRNA synthetase, cytoplasmic (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS).

LZTS1_MOUSE
θ value	2.36792 (rank : 31)	NC score	0.027772 (rank : 36)
Query Neighborhood Hits	70	Target Neighborhood Hits	540	Shared Neighborhood Hits	14
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MCES_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.040151 (rank : 28)
Query Neighborhood Hits	70	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D0L8, Q3V3U9, Q6ZQC6, Q9D5F1	Gene names	Rnmt, Kiaa0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase).

MYO6_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.017412 (rank : 46)
Query Neighborhood Hits	70	Target Neighborhood Hits	727	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

NRBF2_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.031671 (rank : 34)
Query Neighborhood Hits	70	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	Q96F24, Q86UR2, Q96NP6, Q9H0S9, Q9H2I2	Gene names	NRBF2, COPR
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2) (Comodulator of PPAR and RXR).

CD2L5_MOUSE
θ value	3.0926 (rank : 35)	NC score	0.002177 (rank : 70)
Query Neighborhood Hits	70	Target Neighborhood Hits	1011	Shared Neighborhood Hits	11
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

IWS1_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.017754 (rank : 45)
Query Neighborhood Hits	70	Target Neighborhood Hits	1241	Shared Neighborhood Hits	19
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KMHN1_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.014208 (rank : 56)
Query Neighborhood Hits	70	Target Neighborhood Hits	949	Shared Neighborhood Hits	14
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

SYV_MOUSE
θ value	3.0926 (rank : 38)	NC score	0.049778 (rank : 23)
Query Neighborhood Hits	70	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z1Q9, Q9QUN2	Gene names	Vars, Bat6, G7a, Vars2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

XYLT1_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.016814 (rank : 49)
Query Neighborhood Hits	70	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q86Y38, Q9H1B6	Gene names	XYLT1, XT1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (XylT-I) (XT-I) (Peptide O-xylosyltransferase 1).

DOCK4_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.016356 (rank : 51)
Query Neighborhood Hits	70	Target Neighborhood Hits	237	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.016289 (rank : 52)
Query Neighborhood Hits	70	Target Neighborhood Hits	210	Shared Neighborhood Hits	6
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

EF1G_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.048473 (rank : 24)
Query Neighborhood Hits	70	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	P26641, Q6PJ62, Q6PK31, Q96CU2, Q9P196	Gene names	EEF1G, EF1G
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

MECR_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.017221 (rank : 47)
Query Neighborhood Hits	70	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DCS3, Q99L39	Gene names	Mecr, Nrbf1
Domain Architecture	No domain graphic available
Description	Trans-2-enoyl-CoA reductase, mitochondrial precursor (EC 1.3.1.38).

MYH13_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.013815 (rank : 57)
Query Neighborhood Hits	70	Target Neighborhood Hits	1504	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

RBM28_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.011946 (rank : 61)
Query Neighborhood Hits	70	Target Neighborhood Hits	368	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGC6, Q8BG25, Q8VEJ8, Q9CS22, Q9CSE6	Gene names	Rbm28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

REST_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.012659 (rank : 60)
Query Neighborhood Hits	70	Target Neighborhood Hits	1506	Shared Neighborhood Hits	20
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SF3B4_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.009769 (rank : 68)
Query Neighborhood Hits	70	Target Neighborhood Hits	445	Shared Neighborhood Hits	5
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

AFF2_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.014578 (rank : 55)
Query Neighborhood Hits	70	Target Neighborhood Hits	218	Shared Neighborhood Hits	7
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

ATRX_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.015365 (rank : 53)
Query Neighborhood Hits	70	Target Neighborhood Hits	682	Shared Neighborhood Hits	15
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CD2AP_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.034412 (rank : 31)
Query Neighborhood Hits	70	Target Neighborhood Hits	315	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

MO4L2_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.028307 (rank : 35)
Query Neighborhood Hits	70	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

MYH7_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.011777 (rank : 62)
Query Neighborhood Hits	70	Target Neighborhood Hits	1559	Shared Neighborhood Hits	22
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

SCG2_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.036679 (rank : 29)
Query Neighborhood Hits	70	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q03517, Q80Y79, Q9CW80	Gene names	Scg2, Chgc, Scg-2
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

TBC14_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.013404 (rank : 59)
Query Neighborhood Hits	70	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P2M4, Q8IW15	Gene names	TBC1D14, KIAA1322
Domain Architecture
Description	TBC1 domain family member 14.

CKAP2_MOUSE
θ value	6.88961 (rank : 55)	NC score	0.021200 (rank : 40)
Query Neighborhood Hits	70	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q3V1H1, Q66LN2, Q8BSF0	Gene names	Ckap2
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2.

IWS1_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.013691 (rank : 58)
Query Neighborhood Hits	70	Target Neighborhood Hits	1258	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MATR3_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.016773 (rank : 50)
Query Neighborhood Hits	70	Target Neighborhood Hits	325	Shared Neighborhood Hits	10
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

NIPBL_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.025296 (rank : 37)
Query Neighborhood Hits	70	Target Neighborhood Hits	1311	Shared Neighborhood Hits	22
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PRG4_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.024422 (rank : 38)
Query Neighborhood Hits	70	Target Neighborhood Hits	764	Shared Neighborhood Hits	16
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RRP5_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.018681 (rank : 42)
Query Neighborhood Hits	70	Target Neighborhood Hits	291	Shared Neighborhood Hits	11
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

SYNE1_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.011305 (rank : 64)
Query Neighborhood Hits	70	Target Neighborhood Hits	1484	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TITIN_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.001035 (rank : 71)
Query Neighborhood Hits	70	Target Neighborhood Hits	2923	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CDC7_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.004339 (rank : 69)
Query Neighborhood Hits	70	Target Neighborhood Hits	652	Shared Neighborhood Hits	4
SwissProt Accessions	O00311, O00558	Gene names	CDC7, CDC7L1
Domain Architecture
Description	Cell division cycle 7-related protein kinase (EC 2.7.11.1) (CDC7- related kinase) (HsCdc7) (huCdc7).

CF182_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.014581 (rank : 54)
Query Neighborhood Hits	70	Target Neighborhood Hits	474	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IYX8	Gene names	C6orf182
Domain Architecture	No domain graphic available
Description	Protein C6orf182.

CKAP2_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.018660 (rank : 43)
Query Neighborhood Hits	70	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

FEZ2_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.011663 (rank : 63)
Query Neighborhood Hits	70	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHY8, Q76LN0, Q99690	Gene names	FEZ2
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 2 (Zygin-2) (Zygin II).

GOGA4_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.010691 (rank : 65)
Query Neighborhood Hits	70	Target Neighborhood Hits	2034	Shared Neighborhood Hits	27
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MAP1A_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.017046 (rank : 48)
Query Neighborhood Hits	70	Target Neighborhood Hits	1626	Shared Neighborhood Hits	29
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PTN6_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.010068 (rank : 66)
Query Neighborhood Hits	70	Target Neighborhood Hits	234	Shared Neighborhood Hits	5
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

ZN583_HUMAN
θ value	8.99809 (rank : 70)	NC score	-0.000366 (rank : 72)
Query Neighborhood Hits	70	Target Neighborhood Hits	774	Shared Neighborhood Hits	4
SwissProt Accessions	Q96ND8, O14850, Q2NKK3	Gene names	ZNF583
Domain Architecture	No domain graphic available
Description	Zinc finger protein 583 (Zinc finger protein L3-5).

BASP_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.076421 (rank : 19)
Query Neighborhood Hits	70	Target Neighborhood Hits	321	Shared Neighborhood Hits	8
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

TRDN_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.050923 (rank : 22)
Query Neighborhood Hits	70	Target Neighborhood Hits	542	Shared Neighborhood Hits	26
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

Hits sorted by NC score

SYEP_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	70	Target Neighborhood Hits	70	Shared Neighborhood Hits	70
SwissProt Accessions	P07814	Gene names	EPRS, GLNS, PARS, QPRS
Domain Architecture
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

SYEP_MOUSE
NC score	0.965214 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	70	Target Neighborhood Hits	123	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CGC7	Gene names	Eprs, Qprs
Domain Architecture	No domain graphic available
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

SYQ_HUMAN
NC score	0.799268 (rank : 3)	θ value	8.53533e-67 (rank : 3)
Query Neighborhood Hits	70	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P47897	Gene names	QARS
Domain Architecture
Description	Glutaminyl-tRNA synthetase (EC 6.1.1.18) (Glutamine--tRNA ligase) (GlnRS).

SYW_MOUSE
NC score	0.404288 (rank : 4)	θ value	2.0648e-12 (rank : 4)
Query Neighborhood Hits	70	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P32921, Q80ZY4, Q99J58, Q9DC65	Gene names	Wars, Wrs
Domain Architecture
Description	Tryptophanyl-tRNA synthetase (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS).

SYW_HUMAN
NC score	0.370530 (rank : 5)	θ value	1.25267e-09 (rank : 5)
Query Neighborhood Hits	70	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P23381, P78535, Q9UDL3	Gene names	WARS, WRS
Domain Architecture
Description	Tryptophanyl-tRNA synthetase (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS) (IFP53) (hWRS).

MCA3_MOUSE
NC score	0.226003 (rank : 6)	θ value	0.00665767 (rank : 9)
Query Neighborhood Hits	70	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D1M4	Gene names	Eef1e1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation elongation factor 1 epsilon-1 (Multisynthetase complex auxiliary component p18) (Elongation factor p18).

SYM_HUMAN
NC score	0.213020 (rank : 7)	θ value	5.44631e-05 (rank : 6)
Query Neighborhood Hits	70	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	P56192, Q14895, Q53H14, Q96A15, Q96BZ0, Q9NSE0	Gene names	MARS
Domain Architecture
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

MCA3_HUMAN
NC score	0.206086 (rank : 8)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	70	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	O43324, Q5THS2	Gene names	EEF1E1
Domain Architecture
Description	Eukaryotic translation elongation factor 1 epsilon-1 (Multisynthetase complex auxiliary component p18) (Elongation factor p18).

SYM_MOUSE
NC score	0.191728 (rank : 9)	θ value	0.00102713 (rank : 8)
Query Neighborhood Hits	70	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q68FL6	Gene names	Mars
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

SYG_MOUSE
NC score	0.165709 (rank : 10)	θ value	0.00102713 (rank : 7)
Query Neighborhood Hits	70	Target Neighborhood Hits	27	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CZD3, Q8VC67	Gene names	Gars
Domain Architecture
Description	Glycyl-tRNA synthetase (EC 6.1.1.14) (Glycine--tRNA ligase) (GlyRS).

SYG_HUMAN
NC score	0.147897 (rank : 11)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	70	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	P41250, Q969Y1	Gene names	GARS
Domain Architecture
Description	Glycyl-tRNA synthetase (EC 6.1.1.14) (Glycine--tRNA ligase) (GlyRS).

MCA2_HUMAN
NC score	0.135605 (rank : 12)	θ value	0.21417 (rank : 20)
Query Neighborhood Hits	70	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q13155, Q96CZ5, Q9P1L2	Gene names	JTV1
Domain Architecture
Description	Multisynthetase complex auxiliary component p38 (Protein JTV-1).

SYPM_MOUSE
NC score	0.115314 (rank : 13)	θ value	0.0961366 (rank : 16)
Query Neighborhood Hits	70	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CFI5, Q8R0C4	Gene names	Pars2
Domain Architecture	No domain graphic available
Description	Probable prolyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.15) (Proline--tRNA ligase) (ProRS).

SYPM_HUMAN
NC score	0.089815 (rank : 14)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	70	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	Q7L3T8, Q9H6S5, Q9UFT1	Gene names	PARS2
Domain Architecture	No domain graphic available
Description	Probable prolyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.15) (Proline--tRNA ligase) (ProRS).

SYTC_HUMAN
NC score	0.087674 (rank : 15)	θ value	0.0563607 (rank : 11)
Query Neighborhood Hits	70	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	P26639, Q96FP5, Q9BWA6	Gene names	TARS
Domain Architecture
Description	Threonyl-tRNA synthetase, cytoplasmic (EC 6.1.1.3) (Threonine--tRNA ligase) (ThrRS).

SYTC_MOUSE
NC score	0.087605 (rank : 16)	θ value	0.0563607 (rank : 12)
Query Neighborhood Hits	70	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D0R2, Q3TL42, Q7TMQ2, Q8BMI6, Q9CX03	Gene names	Tars
Domain Architecture	No domain graphic available
Description	Threonyl-tRNA synthetase, cytoplasmic (EC 6.1.1.3) (Threonine--tRNA ligase) (ThrRS).

SYH_MOUSE
NC score	0.083006 (rank : 17)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	70	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q61035	Gene names	Hars
Domain Architecture
Description	Histidyl-tRNA synthetase (EC 6.1.1.21) (Histidine--tRNA ligase) (HisRS).

SYH_HUMAN
NC score	0.080436 (rank : 18)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	70	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	P12081	Gene names	HARS, HRS
Domain Architecture
Description	Histidyl-tRNA synthetase (EC 6.1.1.21) (Histidine--tRNA ligase) (HisRS).

BASP_HUMAN
NC score	0.076421 (rank : 19)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	70	Target Neighborhood Hits	321	Shared Neighborhood Hits	8
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

GP155_HUMAN
NC score	0.071812 (rank : 20)	θ value	0.279714 (rank : 21)
Query Neighborhood Hits	70	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

NCF2_HUMAN
NC score	0.053010 (rank : 21)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	70	Target Neighborhood Hits	229	Shared Neighborhood Hits	6
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

TRDN_HUMAN
NC score	0.050923 (rank : 22)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	70	Target Neighborhood Hits	542	Shared Neighborhood Hits	26
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

SYV_MOUSE
NC score	0.049778 (rank : 23)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	70	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z1Q9, Q9QUN2	Gene names	Vars, Bat6, G7a, Vars2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

EF1G_HUMAN
NC score	0.048473 (rank : 24)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	70	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	P26641, Q6PJ62, Q6PK31, Q96CU2, Q9P196	Gene names	EEF1G, EF1G
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

SYCC_MOUSE
NC score	0.046042 (rank : 25)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	70	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ER72, O88303, Q8BP81, Q8CAY7, Q8CCE3, Q8K0S4, Q9ER68	Gene names	Cars
Domain Architecture
Description	Cysteinyl-tRNA synthetase, cytoplasmic (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS).

CD2AP_MOUSE
NC score	0.044815 (rank : 26)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	70	Target Neighborhood Hits	336	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

RRBP1_HUMAN
NC score	0.040605 (rank : 27)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	70	Target Neighborhood Hits	1306	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

MCES_MOUSE
NC score	0.040151 (rank : 28)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	70	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D0L8, Q3V3U9, Q6ZQC6, Q9D5F1	Gene names	Rnmt, Kiaa0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase).

SCG2_MOUSE
NC score	0.036679 (rank : 29)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	70	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q03517, Q80Y79, Q9CW80	Gene names	Scg2, Chgc, Scg-2
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

ESCO1_HUMAN
NC score	0.035430 (rank : 30)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	70	Target Neighborhood Hits	361	Shared Neighborhood Hits	15
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

CD2AP_HUMAN
NC score	0.034412 (rank : 31)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	70	Target Neighborhood Hits	315	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

RRBP1_MOUSE
NC score	0.033558 (rank : 32)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	70	Target Neighborhood Hits	1650	Shared Neighborhood Hits	26
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

PTPRZ_HUMAN
NC score	0.032002 (rank : 33)	θ value	0.0252991 (rank : 10)
Query Neighborhood Hits	70	Target Neighborhood Hits	255	Shared Neighborhood Hits	7
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

NRBF2_HUMAN
NC score	0.031671 (rank : 34)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	70	Target Neighborhood Hits	122	Shared Neighborhood Hits	7
SwissProt Accessions	Q96F24, Q86UR2, Q96NP6, Q9H0S9, Q9H2I2	Gene names	NRBF2, COPR
Domain Architecture	No domain graphic available
Description	Nuclear receptor-binding factor 2 (NRBF-2) (Comodulator of PPAR and RXR).

MO4L2_HUMAN
NC score	0.028307 (rank : 35)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	70	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

LZTS1_MOUSE
NC score	0.027772 (rank : 36)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	70	Target Neighborhood Hits	540	Shared Neighborhood Hits	14
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

NIPBL_HUMAN
NC score	0.025296 (rank : 37)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	70	Target Neighborhood Hits	1311	Shared Neighborhood Hits	22
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PRG4_HUMAN
NC score	0.024422 (rank : 38)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	70	Target Neighborhood Hits	764	Shared Neighborhood Hits	16
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SRBS1_MOUSE
NC score	0.023995 (rank : 39)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	70	Target Neighborhood Hits	409	Shared Neighborhood Hits	12
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

CKAP2_MOUSE
NC score	0.021200 (rank : 40)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	70	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q3V1H1, Q66LN2, Q8BSF0	Gene names	Ckap2
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2.

CN145_HUMAN
NC score	0.018772 (rank : 41)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	70	Target Neighborhood Hits	1196	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

RRP5_HUMAN
NC score	0.018681 (rank : 42)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	70	Target Neighborhood Hits	291	Shared Neighborhood Hits	11
SwissProt Accessions	Q14690, Q86VQ8	Gene names	PDCD11, KIAA0185
Domain Architecture
Description	RRP5 protein homolog (Programmed cell death protein 11).

CKAP2_HUMAN
NC score	0.018660 (rank : 43)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	70	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

LAMA2_MOUSE
NC score	0.018554 (rank : 44)	θ value	0.279714 (rank : 22)
Query Neighborhood Hits	70	Target Neighborhood Hits	1198	Shared Neighborhood Hits	17
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

IWS1_HUMAN
NC score	0.017754 (rank : 45)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	70	Target Neighborhood Hits	1241	Shared Neighborhood Hits	19
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MYO6_HUMAN
NC score	0.017412 (rank : 46)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	70	Target Neighborhood Hits	727	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

MECR_MOUSE
NC score	0.017221 (rank : 47)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	70	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DCS3, Q99L39	Gene names	Mecr, Nrbf1
Domain Architecture	No domain graphic available
Description	Trans-2-enoyl-CoA reductase, mitochondrial precursor (EC 1.3.1.38).

MAP1A_HUMAN
NC score	0.017046 (rank : 48)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	70	Target Neighborhood Hits	1626	Shared Neighborhood Hits	29
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

XYLT1_HUMAN
NC score	0.016814 (rank : 49)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	70	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q86Y38, Q9H1B6	Gene names	XYLT1, XT1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (XylT-I) (XT-I) (Peptide O-xylosyltransferase 1).

MATR3_HUMAN
NC score	0.016773 (rank : 50)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	70	Target Neighborhood Hits	325	Shared Neighborhood Hits	10
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

DOCK4_HUMAN
NC score	0.016356 (rank : 51)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	70	Target Neighborhood Hits	237	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
NC score	0.016289 (rank : 52)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	70	Target Neighborhood Hits	210	Shared Neighborhood Hits	6
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

ATRX_MOUSE
NC score	0.015365 (rank : 53)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	70	Target Neighborhood Hits	682	Shared Neighborhood Hits	15
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CF182_HUMAN
NC score	0.014581 (rank : 54)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	70	Target Neighborhood Hits	474	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IYX8	Gene names	C6orf182
Domain Architecture	No domain graphic available
Description	Protein C6orf182.

AFF2_HUMAN
NC score	0.014578 (rank : 55)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	70	Target Neighborhood Hits	218	Shared Neighborhood Hits	7
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

KMHN1_MOUSE
NC score	0.014208 (rank : 56)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	70	Target Neighborhood Hits	949	Shared Neighborhood Hits	14
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

MYH13_HUMAN
NC score	0.013815 (rank : 57)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	70	Target Neighborhood Hits	1504	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

IWS1_MOUSE
NC score	0.013691 (rank : 58)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	70	Target Neighborhood Hits	1258	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TBC14_HUMAN
NC score	0.013404 (rank : 59)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	70	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P2M4, Q8IW15	Gene names	TBC1D14, KIAA1322
Domain Architecture
Description	TBC1 domain family member 14.

REST_MOUSE
NC score	0.012659 (rank : 60)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	70	Target Neighborhood Hits	1506	Shared Neighborhood Hits	20
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RBM28_MOUSE
NC score	0.011946 (rank : 61)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	70	Target Neighborhood Hits	368	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGC6, Q8BG25, Q8VEJ8, Q9CS22, Q9CSE6	Gene names	Rbm28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

MYH7_HUMAN
NC score	0.011777 (rank : 62)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	70	Target Neighborhood Hits	1559	Shared Neighborhood Hits	22
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

FEZ2_HUMAN
NC score	0.011663 (rank : 63)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	70	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHY8, Q76LN0, Q99690	Gene names	FEZ2
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 2 (Zygin-2) (Zygin II).

SYNE1_HUMAN
NC score	0.011305 (rank : 64)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	70	Target Neighborhood Hits	1484	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

GOGA4_HUMAN
NC score	0.010691 (rank : 65)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	70	Target Neighborhood Hits	2034	Shared Neighborhood Hits	27
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

PTN6_HUMAN
NC score	0.010068 (rank : 66)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	70	Target Neighborhood Hits	234	Shared Neighborhood Hits	5
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

ZN217_HUMAN
NC score	0.009921 (rank : 67)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	70	Target Neighborhood Hits	905	Shared Neighborhood Hits	5
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

SF3B4_HUMAN
NC score	0.009769 (rank : 68)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	70	Target Neighborhood Hits	445	Shared Neighborhood Hits	5
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

CDC7_HUMAN
NC score	0.004339 (rank : 69)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	70	Target Neighborhood Hits	652	Shared Neighborhood Hits	4
SwissProt Accessions	O00311, O00558	Gene names	CDC7, CDC7L1
Domain Architecture
Description	Cell division cycle 7-related protein kinase (EC 2.7.11.1) (CDC7- related kinase) (HsCdc7) (huCdc7).

CD2L5_MOUSE
NC score	0.002177 (rank : 70)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	70	Target Neighborhood Hits	1011	Shared Neighborhood Hits	11
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

TITIN_HUMAN
NC score	0.001035 (rank : 71)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	70	Target Neighborhood Hits	2923	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZN583_HUMAN
NC score	-0.000366 (rank : 72)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	70	Target Neighborhood Hits	774	Shared Neighborhood Hits	4
SwissProt Accessions	Q96ND8, O14850, Q2NKK3	Gene names	ZNF583
Domain Architecture	No domain graphic available
Description	Zinc finger protein 583 (Zinc finger protein L3-5).