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Network neighborhood for query Sequence : SYW_HUMAN

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SYW_HUMAN
SwissProt Accessions	P23381, P78535, Q9UDL3	Gene names	WARS, WRS
Domain Architecture
Description	Tryptophanyl-tRNA synthetase (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS) (IFP53) (hWRS).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SYW_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P23381, P78535, Q9UDL3	Gene names	WARS, WRS
Domain Architecture
Description	Tryptophanyl-tRNA synthetase (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS) (IFP53) (hWRS).

SYW_MOUSE
θ value	0 (rank : 2)	NC score	0.996243 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	P32921, Q80ZY4, Q99J58, Q9DC65	Gene names	Wars, Wrs
Domain Architecture
Description	Tryptophanyl-tRNA synthetase (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS).

SYEP_HUMAN
θ value	1.25267e-09 (rank : 3)	NC score	0.370530 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	P07814	Gene names	EPRS, GLNS, PARS, QPRS
Domain Architecture
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

SYEP_MOUSE
θ value	1.06045e-08 (rank : 4)	NC score	0.350932 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	123	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CGC7	Gene names	Eprs, Qprs
Domain Architecture	No domain graphic available
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

SYYC_MOUSE
θ value	0.0113563 (rank : 5)	NC score	0.155959 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WQ3, Q3TEC8, Q3U9A1, Q3UTA7, Q8BVT2, Q8C183	Gene names	Yars
Domain Architecture	No domain graphic available
Description	Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).

SYYC_HUMAN
θ value	0.0148317 (rank : 6)	NC score	0.156160 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	P54577, O43276, Q53EN1	Gene names	YARS
Domain Architecture
Description	Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).

SYM_HUMAN
θ value	0.0252991 (rank : 7)	NC score	0.144055 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	P56192, Q14895, Q53H14, Q96A15, Q96BZ0, Q9NSE0	Gene names	MARS
Domain Architecture
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

SYWM_MOUSE
θ value	0.163984 (rank : 8)	NC score	0.107189 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CYK1	Gene names	Wars2
Domain Architecture
Description	Tryptophanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS) ((Mt)TrpRS).

SYM_MOUSE
θ value	1.38821 (rank : 9)	NC score	0.112180 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q68FL6	Gene names	Mars
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

TACC3_HUMAN
θ value	1.38821 (rank : 10)	NC score	0.020980 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	779	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

MMP17_MOUSE
θ value	1.81305 (rank : 11)	NC score	0.012326 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0S3	Gene names	Mmp17, Mt4mmp
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

ZBT20_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.002877 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	835	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HC78	Gene names	ZBTB20, DPZF, ZNF288
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 20 (Zinc finger protein 288) (Dendritic-derived BTB/POZ zinc finger protein).

AATK_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.002338 (rank : 14)
Query Neighborhood Hits	13	Target Neighborhood Hits	1243	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

SYQ_HUMAN
θ value	θ > 10 (rank : 14)	NC score	0.130608 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P47897	Gene names	QARS
Domain Architecture
Description	Glutaminyl-tRNA synthetase (EC 6.1.1.18) (Glutamine--tRNA ligase) (GlnRS).

Hits sorted by NC score

SYW_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P23381, P78535, Q9UDL3	Gene names	WARS, WRS
Domain Architecture
Description	Tryptophanyl-tRNA synthetase (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS) (IFP53) (hWRS).

SYW_MOUSE
NC score	0.996243 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	P32921, Q80ZY4, Q99J58, Q9DC65	Gene names	Wars, Wrs
Domain Architecture
Description	Tryptophanyl-tRNA synthetase (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS).

SYEP_HUMAN
NC score	0.370530 (rank : 3)	θ value	1.25267e-09 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	P07814	Gene names	EPRS, GLNS, PARS, QPRS
Domain Architecture
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

SYEP_MOUSE
NC score	0.350932 (rank : 4)	θ value	1.06045e-08 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	123	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CGC7	Gene names	Eprs, Qprs
Domain Architecture	No domain graphic available
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

SYYC_HUMAN
NC score	0.156160 (rank : 5)	θ value	0.0148317 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	P54577, O43276, Q53EN1	Gene names	YARS
Domain Architecture
Description	Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).

SYYC_MOUSE
NC score	0.155959 (rank : 6)	θ value	0.0113563 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q91WQ3, Q3TEC8, Q3U9A1, Q3UTA7, Q8BVT2, Q8C183	Gene names	Yars
Domain Architecture	No domain graphic available
Description	Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).

SYM_HUMAN
NC score	0.144055 (rank : 7)	θ value	0.0252991 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	P56192, Q14895, Q53H14, Q96A15, Q96BZ0, Q9NSE0	Gene names	MARS
Domain Architecture
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

SYQ_HUMAN
NC score	0.130608 (rank : 8)	θ value	θ > 10 (rank : 14)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P47897	Gene names	QARS
Domain Architecture
Description	Glutaminyl-tRNA synthetase (EC 6.1.1.18) (Glutamine--tRNA ligase) (GlnRS).

SYM_MOUSE
NC score	0.112180 (rank : 9)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q68FL6	Gene names	Mars
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

SYWM_MOUSE
NC score	0.107189 (rank : 10)	θ value	0.163984 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CYK1	Gene names	Wars2
Domain Architecture
Description	Tryptophanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS) ((Mt)TrpRS).

TACC3_HUMAN
NC score	0.020980 (rank : 11)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	779	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

MMP17_MOUSE
NC score	0.012326 (rank : 12)	θ value	1.81305 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0S3	Gene names	Mmp17, Mt4mmp
Domain Architecture
Description	Matrix metalloproteinase-17 precursor (EC 3.4.24.-) (MMP-17) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP).

ZBT20_HUMAN
NC score	0.002877 (rank : 13)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	835	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HC78	Gene names	ZBTB20, DPZF, ZNF288
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 20 (Zinc finger protein 288) (Dendritic-derived BTB/POZ zinc finger protein).

AATK_HUMAN
NC score	0.002338 (rank : 14)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	1243	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).