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Network neighborhood for query Sequence : ODO2_HUMAN

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ODO2_HUMAN
SwissProt Accessions	P36957, Q9BQ32	Gene names	DLST, DLTS
Domain Architecture
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ODO2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	58	Target Neighborhood Hits	58	Shared Neighborhood Hits	58
SwissProt Accessions	P36957, Q9BQ32	Gene names	DLST, DLTS
Domain Architecture
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

ODO2_MOUSE
θ value	0 (rank : 2)	NC score	0.978854 (rank : 2)
Query Neighborhood Hits	58	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D2G2	Gene names	Dlst
Domain Architecture	No domain graphic available
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

ODB2_HUMAN
θ value	1.92365e-26 (rank : 3)	NC score	0.764564 (rank : 4)
Query Neighborhood Hits	58	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P11182	Gene names	DBT, BCATE2
Domain Architecture
Description	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial precursor (EC 2.3.1.168) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide branched chain transacylase) (BCKAD E2 subunit).

ODPX_HUMAN
θ value	5.59698e-26 (rank : 4)	NC score	0.757004 (rank : 6)
Query Neighborhood Hits	58	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	O00330, O60221, Q96FV8, Q99783	Gene names	PDHX, PDX1
Domain Architecture
Description	Pyruvate dehydrogenase protein X component, mitochondrial precursor (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (Lipoyl-containing pyruvate dehydrogenase complex component X) (E3-binding protein) (E3BP) (proX).

ODB2_MOUSE
θ value	2.12685e-25 (rank : 5)	NC score	0.762066 (rank : 5)
Query Neighborhood Hits	58	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	P53395	Gene names	Dbt
Domain Architecture
Description	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial precursor (EC 2.3.1.168) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide branched chain transacylase) (BCKAD E2 subunit).

ODP2_HUMAN
θ value	1.37858e-24 (rank : 6)	NC score	0.765455 (rank : 3)
Query Neighborhood Hits	58	Target Neighborhood Hits	59	Shared Neighborhood Hits	15
SwissProt Accessions	P10515, Q16783	Gene names	DLAT, DLTA
Domain Architecture
Description	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.12) (Pyruvate dehydrogenase complex E2 subunit) (PDCE2) (E2) (Dihydrolipoamide S- acetyltransferase component of pyruvate dehydrogenase complex) (PDC- E2) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (M2 antigen complex 70 kDa subunit).

ODPX_MOUSE
θ value	1.6852e-22 (rank : 7)	NC score	0.745265 (rank : 7)
Query Neighborhood Hits	58	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BKZ9	Gene names	Pdhx
Domain Architecture	No domain graphic available
Description	Pyruvate dehydrogenase protein X component, mitochondrial precursor (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (Lipoyl-containing pyruvate dehydrogenase complex component X).

NACAM_MOUSE
θ value	0.0148317 (rank : 8)	NC score	0.070947 (rank : 9)
Query Neighborhood Hits	58	Target Neighborhood Hits	1866	Shared Neighborhood Hits	45
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CIC_HUMAN
θ value	0.163984 (rank : 9)	NC score	0.080761 (rank : 8)
Query Neighborhood Hits	58	Target Neighborhood Hits	992	Shared Neighborhood Hits	37
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CEL_HUMAN
θ value	0.279714 (rank : 10)	NC score	0.037805 (rank : 23)
Query Neighborhood Hits	58	Target Neighborhood Hits	896	Shared Neighborhood Hits	27
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CIC_MOUSE
θ value	0.365318 (rank : 11)	NC score	0.068687 (rank : 10)
Query Neighborhood Hits	58	Target Neighborhood Hits	742	Shared Neighborhood Hits	30
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MUC1_HUMAN
θ value	0.365318 (rank : 12)	NC score	0.049740 (rank : 14)
Query Neighborhood Hits	58	Target Neighborhood Hits	975	Shared Neighborhood Hits	32
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SEPT9_HUMAN
θ value	0.365318 (rank : 13)	NC score	0.034249 (rank : 24)
Query Neighborhood Hits	58	Target Neighborhood Hits	706	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

ARMX2_MOUSE
θ value	0.62314 (rank : 14)	NC score	0.045801 (rank : 15)
Query Neighborhood Hits	58	Target Neighborhood Hits	349	Shared Neighborhood Hits	21
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

MAVS_HUMAN
θ value	0.813845 (rank : 15)	NC score	0.055347 (rank : 12)
Query Neighborhood Hits	58	Target Neighborhood Hits	271	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

OGFR_HUMAN
θ value	0.813845 (rank : 16)	NC score	0.053417 (rank : 13)
Query Neighborhood Hits	58	Target Neighborhood Hits	1582	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

ZN687_HUMAN
θ value	0.813845 (rank : 17)	NC score	0.018528 (rank : 42)
Query Neighborhood Hits	58	Target Neighborhood Hits	1244	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

LAMC1_HUMAN
θ value	1.06291 (rank : 18)	NC score	0.010704 (rank : 49)
Query Neighborhood Hits	58	Target Neighborhood Hits	922	Shared Neighborhood Hits	7
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

SYNJ1_MOUSE
θ value	1.06291 (rank : 19)	NC score	0.043743 (rank : 17)
Query Neighborhood Hits	58	Target Neighborhood Hits	516	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

NOTC2_MOUSE
θ value	1.38821 (rank : 20)	NC score	0.009438 (rank : 53)
Query Neighborhood Hits	58	Target Neighborhood Hits	1069	Shared Neighborhood Hits	14
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SON_HUMAN
θ value	1.81305 (rank : 21)	NC score	0.040826 (rank : 21)
Query Neighborhood Hits	58	Target Neighborhood Hits	1568	Shared Neighborhood Hits	41
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TP53B_MOUSE
θ value	1.81305 (rank : 22)	NC score	0.039128 (rank : 22)
Query Neighborhood Hits	58	Target Neighborhood Hits	644	Shared Neighborhood Hits	23
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TACC2_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.020124 (rank : 41)
Query Neighborhood Hits	58	Target Neighborhood Hits	856	Shared Neighborhood Hits	20
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

BAT2_HUMAN
θ value	3.0926 (rank : 24)	NC score	0.057066 (rank : 11)
Query Neighborhood Hits	58	Target Neighborhood Hits	931	Shared Neighborhood Hits	37
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAZ2A_MOUSE
θ value	3.0926 (rank : 25)	NC score	0.028948 (rank : 29)
Query Neighborhood Hits	58	Target Neighborhood Hits	744	Shared Neighborhood Hits	28
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

DEAF1_MOUSE
θ value	3.0926 (rank : 26)	NC score	0.022464 (rank : 36)
Query Neighborhood Hits	58	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

PCLO_MOUSE
θ value	3.0926 (rank : 27)	NC score	0.032922 (rank : 25)
Query Neighborhood Hits	58	Target Neighborhood Hits	2275	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PO6F1_MOUSE
θ value	3.0926 (rank : 28)	NC score	0.029159 (rank : 28)
Query Neighborhood Hits	58	Target Neighborhood Hits	581	Shared Neighborhood Hits	19
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

TM108_MOUSE
θ value	3.0926 (rank : 29)	NC score	0.044479 (rank : 16)
Query Neighborhood Hits	58	Target Neighborhood Hits	336	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

CHMP6_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.025202 (rank : 32)
Query Neighborhood Hits	58	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q96FZ7, Q53FU4, Q9HAE8	Gene names	CHMP6, VPS20
Domain Architecture	No domain graphic available
Description	Charged multivesicular body protein 6 (Chromatin-modifying protein 6) (Vacuolar protein sorting-associated protein 20) (hVps20).

CSKI1_MOUSE
θ value	4.03905 (rank : 31)	NC score	0.022127 (rank : 37)
Query Neighborhood Hits	58	Target Neighborhood Hits	1031	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

HGS_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.016673 (rank : 45)
Query Neighborhood Hits	58	Target Neighborhood Hits	517	Shared Neighborhood Hits	16
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

ZBT16_HUMAN
θ value	4.03905 (rank : 33)	NC score	0.000301 (rank : 58)
Query Neighborhood Hits	58	Target Neighborhood Hits	1010	Shared Neighborhood Hits	11
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

ACINU_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.021434 (rank : 40)
Query Neighborhood Hits	58	Target Neighborhood Hits	712	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

BAZ2A_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.041547 (rank : 20)
Query Neighborhood Hits	58	Target Neighborhood Hits	780	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BSN_MOUSE
θ value	5.27518 (rank : 36)	NC score	0.042695 (rank : 18)
Query Neighborhood Hits	58	Target Neighborhood Hits	2057	Shared Neighborhood Hits	46
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CC28B_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.021588 (rank : 38)
Query Neighborhood Hits	58	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BUN5, Q8TBV8	Gene names	CCDC28B
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 28B.

COIA1_MOUSE
θ value	5.27518 (rank : 38)	NC score	0.016947 (rank : 43)
Query Neighborhood Hits	58	Target Neighborhood Hits	481	Shared Neighborhood Hits	21
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CS021_HUMAN
θ value	5.27518 (rank : 39)	NC score	0.023999 (rank : 33)
Query Neighborhood Hits	58	Target Neighborhood Hits	98	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

G3BP_MOUSE
θ value	5.27518 (rank : 40)	NC score	0.012636 (rank : 47)
Query Neighborhood Hits	58	Target Neighborhood Hits	209	Shared Neighborhood Hits	4
SwissProt Accessions	P97855	Gene names	G3bp, G3bp1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

GORS2_MOUSE
θ value	5.27518 (rank : 41)	NC score	0.025849 (rank : 31)
Query Neighborhood Hits	58	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	Q99JX3, Q3U9D2, Q8CCD0, Q91W68	Gene names	Gorasp2
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 2 (GRS2) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55).

MAST4_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.007407 (rank : 54)
Query Neighborhood Hits	58	Target Neighborhood Hits	1804	Shared Neighborhood Hits	32
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MBB1A_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.032068 (rank : 26)
Query Neighborhood Hits	58	Target Neighborhood Hits	665	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MKL1_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.022524 (rank : 35)
Query Neighborhood Hits	58	Target Neighborhood Hits	667	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NFH_MOUSE
θ value	5.27518 (rank : 45)	NC score	0.025961 (rank : 30)
Query Neighborhood Hits	58	Target Neighborhood Hits	2247	Shared Neighborhood Hits	35
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ALMS1_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.022614 (rank : 34)
Query Neighborhood Hits	58	Target Neighborhood Hits	356	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

BAT2_MOUSE
θ value	6.88961 (rank : 47)	NC score	0.042332 (rank : 19)
Query Neighborhood Hits	58	Target Neighborhood Hits	947	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

FREA_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.006280 (rank : 55)
Query Neighborhood Hits	58	Target Neighborhood Hits	205	Shared Neighborhood Hits	10
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

K1802_MOUSE
θ value	6.88961 (rank : 49)	NC score	0.021506 (rank : 39)
Query Neighborhood Hits	58	Target Neighborhood Hits	1596	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MEGF9_MOUSE
θ value	6.88961 (rank : 50)	NC score	0.029906 (rank : 27)
Query Neighborhood Hits	58	Target Neighborhood Hits	896	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

REL_MOUSE
θ value	6.88961 (rank : 51)	NC score	0.011423 (rank : 48)
Query Neighborhood Hits	58	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

WNK1_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.010139 (rank : 51)
Query Neighborhood Hits	58	Target Neighborhood Hits	1158	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

DYNA_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.006238 (rank : 56)
Query Neighborhood Hits	58	Target Neighborhood Hits	1194	Shared Neighborhood Hits	16
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

EP400_MOUSE
θ value	8.99809 (rank : 54)	NC score	0.016687 (rank : 44)
Query Neighborhood Hits	58	Target Neighborhood Hits	592	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

MYLK_MOUSE
θ value	8.99809 (rank : 55)	NC score	0.005697 (rank : 57)
Query Neighborhood Hits	58	Target Neighborhood Hits	1489	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

PHLB1_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.014488 (rank : 46)
Query Neighborhood Hits	58	Target Neighborhood Hits	1038	Shared Neighborhood Hits	25
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

UBP10_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.009814 (rank : 52)
Query Neighborhood Hits	58	Target Neighborhood Hits	153	Shared Neighborhood Hits	5
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

WNK2_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.010453 (rank : 50)
Query Neighborhood Hits	58	Target Neighborhood Hits	1407	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

Hits sorted by NC score

ODO2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	58	Target Neighborhood Hits	58	Shared Neighborhood Hits	58
SwissProt Accessions	P36957, Q9BQ32	Gene names	DLST, DLTS
Domain Architecture
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

ODO2_MOUSE
NC score	0.978854 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	58	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D2G2	Gene names	Dlst
Domain Architecture	No domain graphic available
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

ODP2_HUMAN
NC score	0.765455 (rank : 3)	θ value	1.37858e-24 (rank : 6)
Query Neighborhood Hits	58	Target Neighborhood Hits	59	Shared Neighborhood Hits	15
SwissProt Accessions	P10515, Q16783	Gene names	DLAT, DLTA
Domain Architecture
Description	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.12) (Pyruvate dehydrogenase complex E2 subunit) (PDCE2) (E2) (Dihydrolipoamide S- acetyltransferase component of pyruvate dehydrogenase complex) (PDC- E2) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (M2 antigen complex 70 kDa subunit).

ODB2_HUMAN
NC score	0.764564 (rank : 4)	θ value	1.92365e-26 (rank : 3)
Query Neighborhood Hits	58	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P11182	Gene names	DBT, BCATE2
Domain Architecture
Description	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial precursor (EC 2.3.1.168) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide branched chain transacylase) (BCKAD E2 subunit).

ODB2_MOUSE
NC score	0.762066 (rank : 5)	θ value	2.12685e-25 (rank : 5)
Query Neighborhood Hits	58	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	P53395	Gene names	Dbt
Domain Architecture
Description	Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial precursor (EC 2.3.1.168) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide branched chain transacylase) (BCKAD E2 subunit).

ODPX_HUMAN
NC score	0.757004 (rank : 6)	θ value	5.59698e-26 (rank : 4)
Query Neighborhood Hits	58	Target Neighborhood Hits	24	Shared Neighborhood Hits	8
SwissProt Accessions	O00330, O60221, Q96FV8, Q99783	Gene names	PDHX, PDX1
Domain Architecture
Description	Pyruvate dehydrogenase protein X component, mitochondrial precursor (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (Lipoyl-containing pyruvate dehydrogenase complex component X) (E3-binding protein) (E3BP) (proX).

ODPX_MOUSE
NC score	0.745265 (rank : 7)	θ value	1.6852e-22 (rank : 7)
Query Neighborhood Hits	58	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BKZ9	Gene names	Pdhx
Domain Architecture	No domain graphic available
Description	Pyruvate dehydrogenase protein X component, mitochondrial precursor (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (Lipoyl-containing pyruvate dehydrogenase complex component X).

CIC_HUMAN
NC score	0.080761 (rank : 8)	θ value	0.163984 (rank : 9)
Query Neighborhood Hits	58	Target Neighborhood Hits	992	Shared Neighborhood Hits	37
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

NACAM_MOUSE
NC score	0.070947 (rank : 9)	θ value	0.0148317 (rank : 8)
Query Neighborhood Hits	58	Target Neighborhood Hits	1866	Shared Neighborhood Hits	45
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CIC_MOUSE
NC score	0.068687 (rank : 10)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	58	Target Neighborhood Hits	742	Shared Neighborhood Hits	30
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

BAT2_HUMAN
NC score	0.057066 (rank : 11)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	58	Target Neighborhood Hits	931	Shared Neighborhood Hits	37
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

MAVS_HUMAN
NC score	0.055347 (rank : 12)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	58	Target Neighborhood Hits	271	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

OGFR_HUMAN
NC score	0.053417 (rank : 13)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	58	Target Neighborhood Hits	1582	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MUC1_HUMAN
NC score	0.049740 (rank : 14)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	58	Target Neighborhood Hits	975	Shared Neighborhood Hits	32
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ARMX2_MOUSE
NC score	0.045801 (rank : 15)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	58	Target Neighborhood Hits	349	Shared Neighborhood Hits	21
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

TM108_MOUSE
NC score	0.044479 (rank : 16)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	58	Target Neighborhood Hits	336	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

SYNJ1_MOUSE
NC score	0.043743 (rank : 17)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	58	Target Neighborhood Hits	516	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

BSN_MOUSE
NC score	0.042695 (rank : 18)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	58	Target Neighborhood Hits	2057	Shared Neighborhood Hits	46
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

BAT2_MOUSE
NC score	0.042332 (rank : 19)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	58	Target Neighborhood Hits	947	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAZ2A_HUMAN
NC score	0.041547 (rank : 20)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	58	Target Neighborhood Hits	780	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

SON_HUMAN
NC score	0.040826 (rank : 21)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	58	Target Neighborhood Hits	1568	Shared Neighborhood Hits	41
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TP53B_MOUSE
NC score	0.039128 (rank : 22)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	58	Target Neighborhood Hits	644	Shared Neighborhood Hits	23
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CEL_HUMAN
NC score	0.037805 (rank : 23)	θ value	0.279714 (rank : 10)
Query Neighborhood Hits	58	Target Neighborhood Hits	896	Shared Neighborhood Hits	27
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

SEPT9_HUMAN
NC score	0.034249 (rank : 24)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	58	Target Neighborhood Hits	706	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

PCLO_MOUSE
NC score	0.032922 (rank : 25)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	58	Target Neighborhood Hits	2275	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MBB1A_HUMAN
NC score	0.032068 (rank : 26)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	58	Target Neighborhood Hits	665	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MEGF9_MOUSE
NC score	0.029906 (rank : 27)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	58	Target Neighborhood Hits	896	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PO6F1_MOUSE
NC score	0.029159 (rank : 28)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	58	Target Neighborhood Hits	581	Shared Neighborhood Hits	19
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

BAZ2A_MOUSE
NC score	0.028948 (rank : 29)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	58	Target Neighborhood Hits	744	Shared Neighborhood Hits	28
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

NFH_MOUSE
NC score	0.025961 (rank : 30)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	58	Target Neighborhood Hits	2247	Shared Neighborhood Hits	35
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

GORS2_MOUSE
NC score	0.025849 (rank : 31)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	58	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	Q99JX3, Q3U9D2, Q8CCD0, Q91W68	Gene names	Gorasp2
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 2 (GRS2) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55).

CHMP6_HUMAN
NC score	0.025202 (rank : 32)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	58	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q96FZ7, Q53FU4, Q9HAE8	Gene names	CHMP6, VPS20
Domain Architecture	No domain graphic available
Description	Charged multivesicular body protein 6 (Chromatin-modifying protein 6) (Vacuolar protein sorting-associated protein 20) (hVps20).

CS021_HUMAN
NC score	0.023999 (rank : 33)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	58	Target Neighborhood Hits	98	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

ALMS1_HUMAN
NC score	0.022614 (rank : 34)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	58	Target Neighborhood Hits	356	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

MKL1_MOUSE
NC score	0.022524 (rank : 35)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	58	Target Neighborhood Hits	667	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

DEAF1_MOUSE
NC score	0.022464 (rank : 36)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	58	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

CSKI1_MOUSE
NC score	0.022127 (rank : 37)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	58	Target Neighborhood Hits	1031	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CC28B_HUMAN
NC score	0.021588 (rank : 38)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	58	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BUN5, Q8TBV8	Gene names	CCDC28B
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 28B.

K1802_MOUSE
NC score	0.021506 (rank : 39)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	58	Target Neighborhood Hits	1596	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ACINU_MOUSE
NC score	0.021434 (rank : 40)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	58	Target Neighborhood Hits	712	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

TACC2_HUMAN
NC score	0.020124 (rank : 41)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	58	Target Neighborhood Hits	856	Shared Neighborhood Hits	20
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

ZN687_HUMAN
NC score	0.018528 (rank : 42)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	58	Target Neighborhood Hits	1244	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

COIA1_MOUSE
NC score	0.016947 (rank : 43)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	58	Target Neighborhood Hits	481	Shared Neighborhood Hits	21
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

EP400_MOUSE
NC score	0.016687 (rank : 44)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	58	Target Neighborhood Hits	592	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

HGS_HUMAN
NC score	0.016673 (rank : 45)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	58	Target Neighborhood Hits	517	Shared Neighborhood Hits	16
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

PHLB1_HUMAN
NC score	0.014488 (rank : 46)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	58	Target Neighborhood Hits	1038	Shared Neighborhood Hits	25
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

G3BP_MOUSE
NC score	0.012636 (rank : 47)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	58	Target Neighborhood Hits	209	Shared Neighborhood Hits	4
SwissProt Accessions	P97855	Gene names	G3bp, G3bp1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

REL_MOUSE
NC score	0.011423 (rank : 48)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	58	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

LAMC1_HUMAN
NC score	0.010704 (rank : 49)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	58	Target Neighborhood Hits	922	Shared Neighborhood Hits	7
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

WNK2_HUMAN
NC score	0.010453 (rank : 50)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	58	Target Neighborhood Hits	1407	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

WNK1_HUMAN
NC score	0.010139 (rank : 51)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	58	Target Neighborhood Hits	1158	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

UBP10_HUMAN
NC score	0.009814 (rank : 52)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	58	Target Neighborhood Hits	153	Shared Neighborhood Hits	5
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

NOTC2_MOUSE
NC score	0.009438 (rank : 53)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	58	Target Neighborhood Hits	1069	Shared Neighborhood Hits	14
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

MAST4_HUMAN
NC score	0.007407 (rank : 54)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	58	Target Neighborhood Hits	1804	Shared Neighborhood Hits	32
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

FREA_HUMAN
NC score	0.006280 (rank : 55)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	58	Target Neighborhood Hits	205	Shared Neighborhood Hits	10
SwissProt Accessions	O43638, Q96D28	Gene names	FKHL18, FREAC10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein).

DYNA_HUMAN
NC score	0.006238 (rank : 56)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	58	Target Neighborhood Hits	1194	Shared Neighborhood Hits	16
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

MYLK_MOUSE
NC score	0.005697 (rank : 57)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	58	Target Neighborhood Hits	1489	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

ZBT16_HUMAN
NC score	0.000301 (rank : 58)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	58	Target Neighborhood Hits	1010	Shared Neighborhood Hits	11
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).