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Network neighborhood for query Sequence : ULA1_HUMAN

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ULA1_HUMAN
SwissProt Accessions	Q13564	Gene names	APPBP1
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 regulatory subunit (Amyloid protein-binding protein 1) (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1) (Protooncogene protein 1) (HPP1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ULA1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q13564	Gene names	APPBP1
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 regulatory subunit (Amyloid protein-binding protein 1) (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1) (Protooncogene protein 1) (HPP1).

ULA1_MOUSE
θ value	0 (rank : 2)	NC score	0.999091 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VBW6, Q8CFL6	Gene names	Appbp1
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 regulatory subunit (Amyloid protein-binding protein 1) (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1).

ULE1A_MOUSE
θ value	1.09232e-21 (rank : 3)	NC score	0.719020 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	13
SwissProt Accessions	Q9R1T2, Q3TWJ0, Q9CSW9	Gene names	Uble1a, Aos1, Sae1, Sua1, Ubl1a1
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating enzyme subunit 1).

ULE1A_HUMAN
θ value	5.42112e-21 (rank : 4)	NC score	0.712213 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBE0, O95717, Q9P020	Gene names	UBLE1A, AOS1, SAE1, SUA1
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating enzyme subunit 1).

UBE1_HUMAN
θ value	1.29331e-14 (rank : 5)	NC score	0.571579 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	P22314, Q96E13	Gene names	UBE1
Domain Architecture
Description	Ubiquitin-activating enzyme E1 (A1S9 protein).

UBE1_MOUSE
θ value	2.20605e-14 (rank : 6)	NC score	0.567151 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q02053, Q542H8	Gene names	Ube1x, Uba1, Ube1
Domain Architecture
Description	Ubiquitin-activating enzyme E1 1.

UBE1L_HUMAN
θ value	7.09661e-13 (rank : 7)	NC score	0.572999 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	P41226	Gene names	UBE1L, UBE2
Domain Architecture
Description	Ubiquitin-activating enzyme E1 homolog (D8).

ULE1B_MOUSE
θ value	7.59969e-07 (rank : 8)	NC score	0.456089 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	56	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1F9, Q8BVX9	Gene names	Uble1b, Sae2, Uba2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

ULE1B_HUMAN
θ value	3.77169e-06 (rank : 9)	NC score	0.451428 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBT2, O95605, Q9NTJ1, Q9UED2	Gene names	UBLE1B, SAE2, UBA2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

UBA3_HUMAN
θ value	1.09739e-05 (rank : 10)	NC score	0.451422 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TBC4, O76088, Q9NTU3	Gene names	UBE1C, UBA3
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin- activating enzyme 3) (NEDD8-activating enzyme E1C) (Ubiquitin- activating enzyme E1C).

UBA3_MOUSE
θ value	1.43324e-05 (rank : 11)	NC score	0.451166 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C878, O88598, Q9D6B7	Gene names	Ube1c, Uba3
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin- activating enzyme 3) (NEDD8-activating enzyme E1C) (Ubiquitin- activating enzyme E1C).

MOCS3_HUMAN
θ value	0.0563607 (rank : 12)	NC score	0.361107 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	O95396	Gene names	MOCS3
Domain Architecture
Description	Molybdenum cofactor synthesis protein 3 (Molybdopterin synthase sulfurylase) (MPT synthase sulfurylase).

PKHG1_HUMAN
θ value	1.81305 (rank : 13)	NC score	0.025812 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

UE1D1_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.173813 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZZ9, Q96ST1	Gene names	UBE1DC1, UBA5
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1).

CJ086_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.057756 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NXX6, Q5SQQ5, Q6P673, Q8WY66, Q9BS90	Gene names	C10orf86
Domain Architecture	No domain graphic available
Description	Protein C10orf86.

AKAP9_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.005230 (rank : 19)
Query Neighborhood Hits	18	Target Neighborhood Hits	1710	Shared Neighborhood Hits	4
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

NXT2_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.018121 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NPJ8, Q5JYV6, Q9H8U0, Q9NQ64, Q9NRL7, Q9Y3M4, Q9Y3M5	Gene names	NXT2
Domain Architecture
Description	NTF2-related export protein 2 (p15-2 protein).

SYCP2_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.022865 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	230	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

UE1D1_MOUSE
θ value	θ > 10 (rank : 19)	NC score	0.148986 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VE47, Q9CYD6	Gene names	Ube1dc1
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme).

Hits sorted by NC score

ULA1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q13564	Gene names	APPBP1
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 regulatory subunit (Amyloid protein-binding protein 1) (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1) (Protooncogene protein 1) (HPP1).

ULA1_MOUSE
NC score	0.999091 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VBW6, Q8CFL6	Gene names	Appbp1
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 regulatory subunit (Amyloid protein-binding protein 1) (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1).

ULE1A_MOUSE
NC score	0.719020 (rank : 3)	θ value	1.09232e-21 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	13
SwissProt Accessions	Q9R1T2, Q3TWJ0, Q9CSW9	Gene names	Uble1a, Aos1, Sae1, Sua1, Ubl1a1
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating enzyme subunit 1).

ULE1A_HUMAN
NC score	0.712213 (rank : 4)	θ value	5.42112e-21 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBE0, O95717, Q9P020	Gene names	UBLE1A, AOS1, SAE1, SUA1
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1A (SUMO-1-activating enzyme subunit 1).

UBE1L_HUMAN
NC score	0.572999 (rank : 5)	θ value	7.09661e-13 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	P41226	Gene names	UBE1L, UBE2
Domain Architecture
Description	Ubiquitin-activating enzyme E1 homolog (D8).

UBE1_HUMAN
NC score	0.571579 (rank : 6)	θ value	1.29331e-14 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	P22314, Q96E13	Gene names	UBE1
Domain Architecture
Description	Ubiquitin-activating enzyme E1 (A1S9 protein).

UBE1_MOUSE
NC score	0.567151 (rank : 7)	θ value	2.20605e-14 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q02053, Q542H8	Gene names	Ube1x, Uba1, Ube1
Domain Architecture
Description	Ubiquitin-activating enzyme E1 1.

ULE1B_MOUSE
NC score	0.456089 (rank : 8)	θ value	7.59969e-07 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	56	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1F9, Q8BVX9	Gene names	Uble1b, Sae2, Uba2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

ULE1B_HUMAN
NC score	0.451428 (rank : 9)	θ value	3.77169e-06 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBT2, O95605, Q9NTJ1, Q9UED2	Gene names	UBLE1B, SAE2, UBA2
Domain Architecture
Description	Ubiquitin-like 1-activating enzyme E1B (SUMO-1-activating enzyme subunit 2) (Anthracycline-associated resistance ARX).

UBA3_HUMAN
NC score	0.451422 (rank : 10)	θ value	1.09739e-05 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TBC4, O76088, Q9NTU3	Gene names	UBE1C, UBA3
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin- activating enzyme 3) (NEDD8-activating enzyme E1C) (Ubiquitin- activating enzyme E1C).

UBA3_MOUSE
NC score	0.451166 (rank : 11)	θ value	1.43324e-05 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C878, O88598, Q9D6B7	Gene names	Ube1c, Uba3
Domain Architecture	No domain graphic available
Description	NEDD8-activating enzyme E1 catalytic subunit (EC 6.3.2.-) (Ubiquitin- activating enzyme 3) (NEDD8-activating enzyme E1C) (Ubiquitin- activating enzyme E1C).

MOCS3_HUMAN
NC score	0.361107 (rank : 12)	θ value	0.0563607 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	O95396	Gene names	MOCS3
Domain Architecture
Description	Molybdenum cofactor synthesis protein 3 (Molybdopterin synthase sulfurylase) (MPT synthase sulfurylase).

UE1D1_HUMAN
NC score	0.173813 (rank : 13)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZZ9, Q96ST1	Gene names	UBE1DC1, UBA5
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1).

UE1D1_MOUSE
NC score	0.148986 (rank : 14)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	18	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VE47, Q9CYD6	Gene names	Ube1dc1
Domain Architecture	No domain graphic available
Description	Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme).

CJ086_HUMAN
NC score	0.057756 (rank : 15)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NXX6, Q5SQQ5, Q6P673, Q8WY66, Q9BS90	Gene names	C10orf86
Domain Architecture	No domain graphic available
Description	Protein C10orf86.

PKHG1_HUMAN
NC score	0.025812 (rank : 16)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

SYCP2_HUMAN
NC score	0.022865 (rank : 17)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	230	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

NXT2_HUMAN
NC score	0.018121 (rank : 18)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NPJ8, Q5JYV6, Q9H8U0, Q9NQ64, Q9NRL7, Q9Y3M4, Q9Y3M5	Gene names	NXT2
Domain Architecture
Description	NTF2-related export protein 2 (p15-2 protein).

AKAP9_HUMAN
NC score	0.005230 (rank : 19)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	1710	Shared Neighborhood Hits	4
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).