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Network neighborhood for query Sequence : SF3B3_HUMAN

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SF3B3_HUMAN
SwissProt Accessions	Q15393, Q9UJ29	Gene names	SF3B3, KIAA0017, SAP130
Domain Architecture
Description	Splicing factor 3B subunit 3 (Spliceosome-associated protein 130) (SAP 130) (SF3b130) (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (STAF130).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SF3B3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q15393, Q9UJ29	Gene names	SF3B3, KIAA0017, SAP130
Domain Architecture
Description	Splicing factor 3B subunit 3 (Spliceosome-associated protein 130) (SAP 130) (SF3b130) (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (STAF130).

DDB1_HUMAN
θ value	6.34462e-54 (rank : 2)	NC score	0.772589 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q16531, O15176, Q13289, Q58F96	Gene names	DDB1
Domain Architecture
Description	DNA damage-binding protein 1 (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor) (DDB p127 subunit) (DDBa) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (Xeroderma pigmentosum group E- complementing protein) (XPCe) (XPE-binding factor) (XPE-BF) (X- associated protein 1) (XAP-1).

CPSF1_HUMAN
θ value	6.41864e-14 (rank : 3)	NC score	0.466268 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q10570, Q96AF0	Gene names	CPSF1, CPSF160
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 160 kDa subunit (CPSF 160 kDa subunit).

CPSF1_MOUSE
θ value	1.42992e-13 (rank : 4)	NC score	0.463132 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPU4	Gene names	Cpsf1, Cpsf160
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 160 kDa subunit (CPSF 160 kDa subunit).

PCDB1_HUMAN
θ value	1.38821 (rank : 5)	NC score	0.009002 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	154	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5F3	Gene names	PCDHB1
Domain Architecture
Description	Protocadherin beta 1 precursor (PCDH-beta1).

G7C_HUMAN
θ value	1.81305 (rank : 6)	NC score	0.037405 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y334, Q5SSR5, Q96QC8, Q9UMP9	Gene names	C6orf27, G7C, NG37
Domain Architecture	No domain graphic available
Description	Protein G7c precursor.

ACHD_HUMAN
θ value	4.03905 (rank : 7)	NC score	0.009613 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q07001, Q52LH4	Gene names	CHRND, ACHRD
Domain Architecture
Description	Acetylcholine receptor protein subunit delta precursor.

CADH7_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.007358 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	152	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULB5, Q9H157	Gene names	CDH7, CDH7L1
Domain Architecture
Description	Cadherin-7 precursor.

KIF25_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.014475 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UIL4, O94775	Gene names	KIF25, KNSL3
Domain Architecture
Description	Kinesin-like protein KIF25 (Kinesin-like protein 3).

ARC1B_MOUSE
θ value	5.27518 (rank : 10)	NC score	0.017213 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	133	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WV32	Gene names	Arpc1b
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa subunit) (p41-ARC).

FA38B_MOUSE
θ value	5.27518 (rank : 11)	NC score	0.021421 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CD54, Q8BSM4	Gene names	Fam38b
Domain Architecture	No domain graphic available
Description	Protein FAM38B.

STAB2_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.007537 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	534	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

LAEVR_HUMAN
θ value	6.88961 (rank : 13)	NC score	0.010700 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	Q6Q4G3, Q32MR1, Q4G0I9, Q4G0V2, Q86XA3, Q8NBZ2	Gene names	LVRN
Domain Architecture	No domain graphic available
Description	Laeverin (EC 3.4.-.-) (CHL2 antigen).

SDK1_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.004933 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	511	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

FANCM_MOUSE
θ value	8.99809 (rank : 15)	NC score	0.012300 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	177	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

MUC18_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.008797 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	292	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

PCLO_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.004616 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	2275	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PVRL1_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.010153 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	201	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JKF6, Q9ERL5, Q9JI17	Gene names	Pvrl1, Hvec, Prr1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (CD111 antigen).

SPHK1_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.016977 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYA1, Q9HD92, Q9NY70, Q9NYL3	Gene names	SPHK1, SPHK, SPK
Domain Architecture
Description	Sphingosine kinase 1 (EC 2.7.1.-) (SK 1) (SPK 1).

Hits sorted by NC score

SF3B3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q15393, Q9UJ29	Gene names	SF3B3, KIAA0017, SAP130
Domain Architecture
Description	Splicing factor 3B subunit 3 (Spliceosome-associated protein 130) (SAP 130) (SF3b130) (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (STAF130).

DDB1_HUMAN
NC score	0.772589 (rank : 2)	θ value	6.34462e-54 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	Q16531, O15176, Q13289, Q58F96	Gene names	DDB1
Domain Architecture
Description	DNA damage-binding protein 1 (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor) (DDB p127 subunit) (DDBa) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (Xeroderma pigmentosum group E- complementing protein) (XPCe) (XPE-binding factor) (XPE-BF) (X- associated protein 1) (XAP-1).

CPSF1_HUMAN
NC score	0.466268 (rank : 3)	θ value	6.41864e-14 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q10570, Q96AF0	Gene names	CPSF1, CPSF160
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 160 kDa subunit (CPSF 160 kDa subunit).

CPSF1_MOUSE
NC score	0.463132 (rank : 4)	θ value	1.42992e-13 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPU4	Gene names	Cpsf1, Cpsf160
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 160 kDa subunit (CPSF 160 kDa subunit).

G7C_HUMAN
NC score	0.037405 (rank : 5)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y334, Q5SSR5, Q96QC8, Q9UMP9	Gene names	C6orf27, G7C, NG37
Domain Architecture	No domain graphic available
Description	Protein G7c precursor.

FA38B_MOUSE
NC score	0.021421 (rank : 6)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CD54, Q8BSM4	Gene names	Fam38b
Domain Architecture	No domain graphic available
Description	Protein FAM38B.

ARC1B_MOUSE
NC score	0.017213 (rank : 7)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	133	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WV32	Gene names	Arpc1b
Domain Architecture
Description	Actin-related protein 2/3 complex subunit 1B (ARP2/3 complex 41 kDa subunit) (p41-ARC).

SPHK1_HUMAN
NC score	0.016977 (rank : 8)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYA1, Q9HD92, Q9NY70, Q9NYL3	Gene names	SPHK1, SPHK, SPK
Domain Architecture
Description	Sphingosine kinase 1 (EC 2.7.1.-) (SK 1) (SPK 1).

KIF25_HUMAN
NC score	0.014475 (rank : 9)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UIL4, O94775	Gene names	KIF25, KNSL3
Domain Architecture
Description	Kinesin-like protein KIF25 (Kinesin-like protein 3).

FANCM_MOUSE
NC score	0.012300 (rank : 10)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	177	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

LAEVR_HUMAN
NC score	0.010700 (rank : 11)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	Q6Q4G3, Q32MR1, Q4G0I9, Q4G0V2, Q86XA3, Q8NBZ2	Gene names	LVRN
Domain Architecture	No domain graphic available
Description	Laeverin (EC 3.4.-.-) (CHL2 antigen).

PVRL1_MOUSE
NC score	0.010153 (rank : 12)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	201	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JKF6, Q9ERL5, Q9JI17	Gene names	Pvrl1, Hvec, Prr1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (CD111 antigen).

ACHD_HUMAN
NC score	0.009613 (rank : 13)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q07001, Q52LH4	Gene names	CHRND, ACHRD
Domain Architecture
Description	Acetylcholine receptor protein subunit delta precursor.

PCDB1_HUMAN
NC score	0.009002 (rank : 14)	θ value	1.38821 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	154	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5F3	Gene names	PCDHB1
Domain Architecture
Description	Protocadherin beta 1 precursor (PCDH-beta1).

MUC18_MOUSE
NC score	0.008797 (rank : 15)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	292	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

STAB2_HUMAN
NC score	0.007537 (rank : 16)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	534	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

CADH7_HUMAN
NC score	0.007358 (rank : 17)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	152	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULB5, Q9H157	Gene names	CDH7, CDH7L1
Domain Architecture
Description	Cadherin-7 precursor.

SDK1_HUMAN
NC score	0.004933 (rank : 18)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	511	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

PCLO_MOUSE
NC score	0.004616 (rank : 19)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	2275	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).