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Network neighborhood for query Sequence : G7C_HUMAN

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G7C_HUMAN
SwissProt Accessions	Q9Y334, Q5SSR5, Q96QC8, Q9UMP9	Gene names	C6orf27, G7C, NG37
Domain Architecture	No domain graphic available
Description	Protein G7c precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

G7C_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y334, Q5SSR5, Q96QC8, Q9UMP9	Gene names	C6orf27, G7C, NG37
Domain Architecture	No domain graphic available
Description	Protein G7c precursor.

G7C_MOUSE
θ value	0 (rank : 2)	NC score	0.992634 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JHA8, Q9Z1Q8	Gene names	D17H6S56E-3, G7c
Domain Architecture	No domain graphic available
Description	Protein G7c precursor.

HMCN1_HUMAN
θ value	1.52067e-31 (rank : 3)	NC score	0.125638 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	983	Shared Neighborhood Hits	5
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

MLL2_HUMAN
θ value	0.163984 (rank : 4)	NC score	0.028943 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	1788	Shared Neighborhood Hits	9
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

OBSCN_HUMAN
θ value	0.21417 (rank : 5)	NC score	0.033124 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	1931	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

OST3B_MOUSE
θ value	0.62314 (rank : 6)	NC score	0.021101 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

SON_HUMAN
θ value	0.813845 (rank : 7)	NC score	0.019063 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	1568	Shared Neighborhood Hits	6
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

DAXX_HUMAN
θ value	1.06291 (rank : 8)	NC score	0.048991 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

MDC1_HUMAN
θ value	1.06291 (rank : 9)	NC score	0.021066 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	1446	Shared Neighborhood Hits	6
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

FOLH1_HUMAN
θ value	1.38821 (rank : 10)	NC score	0.020289 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q04609, O43748, Q16305, Q9NP15, Q9NYE2, Q9P1P8	Gene names	FOLH1, FOLH, NAALAD1, PSM, PSMA
Domain Architecture
Description	Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase II) (Membrane glutamate carboxypeptidase) (mGCP) (N- acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Pteroylpoly-gamma-glutamate carboxypeptidase) (Folylpoly-gamma- glutamate carboxypeptidase) (FGCP) (Folate hydrolase 1) (Prostate- specific membrane antigen) (PSMA) (PSM).

PIDD_HUMAN
θ value	1.81305 (rank : 11)	NC score	0.013715 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	271	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HB75, Q59FD1, Q59H10, Q59HC7, Q7Z4P8, Q8NC89, Q8NDL2, Q96C25, Q9NRE6	Gene names	LRDD, PIDD
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein (p53-induced protein with a death domain).

SF3B3_HUMAN
θ value	1.81305 (rank : 12)	NC score	0.037405 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q15393, Q9UJ29	Gene names	SF3B3, KIAA0017, SAP130
Domain Architecture
Description	Splicing factor 3B subunit 3 (Spliceosome-associated protein 130) (SAP 130) (SF3b130) (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (STAF130).

ZBT20_HUMAN
θ value	1.81305 (rank : 13)	NC score	0.004692 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	835	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HC78	Gene names	ZBTB20, DPZF, ZNF288
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 20 (Zinc finger protein 288) (Dendritic-derived BTB/POZ zinc finger protein).

ASB16_MOUSE
θ value	2.36792 (rank : 14)	NC score	0.010100 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	306	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

CEND3_HUMAN
θ value	2.36792 (rank : 15)	NC score	0.014474 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	275	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

DAXX_MOUSE
θ value	2.36792 (rank : 16)	NC score	0.046416 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

WRN_MOUSE
θ value	2.36792 (rank : 17)	NC score	0.017991 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	295	Shared Neighborhood Hits	2
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

CSPG5_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.021396 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	199	Shared Neighborhood Hits	3
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

CAR10_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.008850 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	569	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

EPHB6_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.002700 (rank : 23)
Query Neighborhood Hits	21	Target Neighborhood Hits	912	Shared Neighborhood Hits	5
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

S6A18_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.004064 (rank : 22)
Query Neighborhood Hits	21	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	O88576, O88577, O88578, O88579, O88580, O88581, Q91XG6	Gene names	Slc6a18, Xt2, Xtrp2
Domain Architecture
Description	Sodium- and chloride-dependent transporter XTRP2 (Solute carrier family 6 member 18).

PROP_HUMAN
θ value	θ > 10 (rank : 22)	NC score	0.052346 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	126	Shared Neighborhood Hits	1
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
θ value	θ > 10 (rank : 23)	NC score	0.050871 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	165	Shared Neighborhood Hits	1
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

Hits sorted by NC score

G7C_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y334, Q5SSR5, Q96QC8, Q9UMP9	Gene names	C6orf27, G7C, NG37
Domain Architecture	No domain graphic available
Description	Protein G7c precursor.

G7C_MOUSE
NC score	0.992634 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JHA8, Q9Z1Q8	Gene names	D17H6S56E-3, G7c
Domain Architecture	No domain graphic available
Description	Protein G7c precursor.

HMCN1_HUMAN
NC score	0.125638 (rank : 3)	θ value	1.52067e-31 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	983	Shared Neighborhood Hits	5
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

PROP_HUMAN
NC score	0.052346 (rank : 4)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	21	Target Neighborhood Hits	126	Shared Neighborhood Hits	1
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
NC score	0.050871 (rank : 5)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	21	Target Neighborhood Hits	165	Shared Neighborhood Hits	1
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

DAXX_HUMAN
NC score	0.048991 (rank : 6)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

DAXX_MOUSE
NC score	0.046416 (rank : 7)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

SF3B3_HUMAN
NC score	0.037405 (rank : 8)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q15393, Q9UJ29	Gene names	SF3B3, KIAA0017, SAP130
Domain Architecture
Description	Splicing factor 3B subunit 3 (Spliceosome-associated protein 130) (SAP 130) (SF3b130) (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (STAF130).

OBSCN_HUMAN
NC score	0.033124 (rank : 9)	θ value	0.21417 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	1931	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

MLL2_HUMAN
NC score	0.028943 (rank : 10)	θ value	0.163984 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	1788	Shared Neighborhood Hits	9
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CSPG5_HUMAN
NC score	0.021396 (rank : 11)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	199	Shared Neighborhood Hits	3
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

OST3B_MOUSE
NC score	0.021101 (rank : 12)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

MDC1_HUMAN
NC score	0.021066 (rank : 13)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	1446	Shared Neighborhood Hits	6
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

FOLH1_HUMAN
NC score	0.020289 (rank : 14)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q04609, O43748, Q16305, Q9NP15, Q9NYE2, Q9P1P8	Gene names	FOLH1, FOLH, NAALAD1, PSM, PSMA
Domain Architecture
Description	Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase II) (Membrane glutamate carboxypeptidase) (mGCP) (N- acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Pteroylpoly-gamma-glutamate carboxypeptidase) (Folylpoly-gamma- glutamate carboxypeptidase) (FGCP) (Folate hydrolase 1) (Prostate- specific membrane antigen) (PSMA) (PSM).

SON_HUMAN
NC score	0.019063 (rank : 15)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	1568	Shared Neighborhood Hits	6
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

WRN_MOUSE
NC score	0.017991 (rank : 16)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	295	Shared Neighborhood Hits	2
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

CEND3_HUMAN
NC score	0.014474 (rank : 17)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	275	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

PIDD_HUMAN
NC score	0.013715 (rank : 18)	θ value	1.81305 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	271	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HB75, Q59FD1, Q59H10, Q59HC7, Q7Z4P8, Q8NC89, Q8NDL2, Q96C25, Q9NRE6	Gene names	LRDD, PIDD
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein (p53-induced protein with a death domain).

ASB16_MOUSE
NC score	0.010100 (rank : 19)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	306	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

CAR10_HUMAN
NC score	0.008850 (rank : 20)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	569	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

ZBT20_HUMAN
NC score	0.004692 (rank : 21)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	835	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HC78	Gene names	ZBTB20, DPZF, ZNF288
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 20 (Zinc finger protein 288) (Dendritic-derived BTB/POZ zinc finger protein).

S6A18_MOUSE
NC score	0.004064 (rank : 22)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	O88576, O88577, O88578, O88579, O88580, O88581, Q91XG6	Gene names	Slc6a18, Xt2, Xtrp2
Domain Architecture
Description	Sodium- and chloride-dependent transporter XTRP2 (Solute carrier family 6 member 18).

EPHB6_HUMAN
NC score	0.002700 (rank : 23)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	912	Shared Neighborhood Hits	5
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).