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Network neighborhood for query Sequence : CPSF1_MOUSE

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CPSF1_MOUSE
SwissProt Accessions	Q9EPU4	Gene names	Cpsf1, Cpsf160
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 160 kDa subunit (CPSF 160 kDa subunit).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CPSF1_HUMAN
θ value	0 (rank : 1)	NC score	0.998197 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q10570, Q96AF0	Gene names	CPSF1, CPSF160
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 160 kDa subunit (CPSF 160 kDa subunit).

CPSF1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EPU4	Gene names	Cpsf1, Cpsf160
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 160 kDa subunit (CPSF 160 kDa subunit).

DDB1_HUMAN
θ value	8.95645e-16 (rank : 3)	NC score	0.496676 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q16531, O15176, Q13289, Q58F96	Gene names	DDB1
Domain Architecture
Description	DNA damage-binding protein 1 (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor) (DDB p127 subunit) (DDBa) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (Xeroderma pigmentosum group E- complementing protein) (XPCe) (XPE-binding factor) (XPE-BF) (X- associated protein 1) (XAP-1).

SF3B3_HUMAN
θ value	1.42992e-13 (rank : 4)	NC score	0.463132 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q15393, Q9UJ29	Gene names	SF3B3, KIAA0017, SAP130
Domain Architecture
Description	Splicing factor 3B subunit 3 (Spliceosome-associated protein 130) (SAP 130) (SF3b130) (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (STAF130).

RFIP5_MOUSE
θ value	1.38821 (rank : 5)	NC score	0.043799 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

SIRT1_MOUSE
θ value	1.38821 (rank : 6)	NC score	0.039080 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q923E4, Q9QXG8	Gene names	Sirt1, Sir2l1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (SIR2alpha) (mSIR2a) (Sir2) (SIR2-like protein 1).

HXC11_HUMAN
θ value	1.81305 (rank : 7)	NC score	0.021956 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	349	Shared Neighborhood Hits	4
SwissProt Accessions	O43248, Q96DH2	Gene names	HOXC11
Domain Architecture
Description	Homeobox protein Hox-C11.

FMOD_MOUSE
θ value	2.36792 (rank : 8)	NC score	0.017768 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	286	Shared Neighborhood Hits	4
SwissProt Accessions	P50608	Gene names	Fmod
Domain Architecture
Description	Fibromodulin precursor (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin).

PDLI3_MOUSE
θ value	2.36792 (rank : 9)	NC score	0.015268 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	197	Shared Neighborhood Hits	2
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

TPR_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.006430 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	1921	Shared Neighborhood Hits	7
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

SMG5_HUMAN
θ value	3.0926 (rank : 11)	NC score	0.021391 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

CCNI_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.035705 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2V9	Gene names	Ccni
Domain Architecture
Description	Cyclin-I.

NOS3_MOUSE
θ value	4.03905 (rank : 13)	NC score	0.012008 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

CABP4_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.012777 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	250	Shared Neighborhood Hits	3
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

CROCC_MOUSE
θ value	5.27518 (rank : 15)	NC score	0.005500 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	1460	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

DOT1L_HUMAN
θ value	5.27518 (rank : 16)	NC score	0.022840 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	660	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

CCNI_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.029384 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q14094	Gene names	CCNI
Domain Architecture
Description	Cyclin-I.

FMOD_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.012715 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	283	Shared Neighborhood Hits	4
SwissProt Accessions	Q06828, Q15331	Gene names	FMOD, FM
Domain Architecture
Description	Fibromodulin precursor (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin).

SPEB_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.031100 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BSE5, Q5TDH1, Q9H5J3	Gene names	AGMAT
Domain Architecture
Description	Agmatinase, mitochondrial precursor (EC 3.5.3.11) (Agmatine ureohydrolase) (AUH).

EVPL_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.005859 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	895	Shared Neighborhood Hits	6
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

RBBP6_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.006186 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	1135	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TBR1_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.005481 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q64336	Gene names	Tbr1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).

Hits sorted by NC score

CPSF1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EPU4	Gene names	Cpsf1, Cpsf160
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 160 kDa subunit (CPSF 160 kDa subunit).

CPSF1_HUMAN
NC score	0.998197 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q10570, Q96AF0	Gene names	CPSF1, CPSF160
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 160 kDa subunit (CPSF 160 kDa subunit).

DDB1_HUMAN
NC score	0.496676 (rank : 3)	θ value	8.95645e-16 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q16531, O15176, Q13289, Q58F96	Gene names	DDB1
Domain Architecture
Description	DNA damage-binding protein 1 (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor) (DDB p127 subunit) (DDBa) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (Xeroderma pigmentosum group E- complementing protein) (XPCe) (XPE-binding factor) (XPE-BF) (X- associated protein 1) (XAP-1).

SF3B3_HUMAN
NC score	0.463132 (rank : 4)	θ value	1.42992e-13 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q15393, Q9UJ29	Gene names	SF3B3, KIAA0017, SAP130
Domain Architecture
Description	Splicing factor 3B subunit 3 (Spliceosome-associated protein 130) (SAP 130) (SF3b130) (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (STAF130).

RFIP5_MOUSE
NC score	0.043799 (rank : 5)	θ value	1.38821 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

SIRT1_MOUSE
NC score	0.039080 (rank : 6)	θ value	1.38821 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q923E4, Q9QXG8	Gene names	Sirt1, Sir2l1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (SIR2alpha) (mSIR2a) (Sir2) (SIR2-like protein 1).

CCNI_MOUSE
NC score	0.035705 (rank : 7)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2V9	Gene names	Ccni
Domain Architecture
Description	Cyclin-I.

SPEB_HUMAN
NC score	0.031100 (rank : 8)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BSE5, Q5TDH1, Q9H5J3	Gene names	AGMAT
Domain Architecture
Description	Agmatinase, mitochondrial precursor (EC 3.5.3.11) (Agmatine ureohydrolase) (AUH).

CCNI_HUMAN
NC score	0.029384 (rank : 9)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q14094	Gene names	CCNI
Domain Architecture
Description	Cyclin-I.

DOT1L_HUMAN
NC score	0.022840 (rank : 10)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	660	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

HXC11_HUMAN
NC score	0.021956 (rank : 11)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	349	Shared Neighborhood Hits	4
SwissProt Accessions	O43248, Q96DH2	Gene names	HOXC11
Domain Architecture
Description	Homeobox protein Hox-C11.

SMG5_HUMAN
NC score	0.021391 (rank : 12)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

FMOD_MOUSE
NC score	0.017768 (rank : 13)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	286	Shared Neighborhood Hits	4
SwissProt Accessions	P50608	Gene names	Fmod
Domain Architecture
Description	Fibromodulin precursor (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin).

PDLI3_MOUSE
NC score	0.015268 (rank : 14)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	197	Shared Neighborhood Hits	2
SwissProt Accessions	O70209	Gene names	Pdlim3
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).

CABP4_HUMAN
NC score	0.012777 (rank : 15)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	250	Shared Neighborhood Hits	3
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

FMOD_HUMAN
NC score	0.012715 (rank : 16)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	283	Shared Neighborhood Hits	4
SwissProt Accessions	Q06828, Q15331	Gene names	FMOD, FM
Domain Architecture
Description	Fibromodulin precursor (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin).

NOS3_MOUSE
NC score	0.012008 (rank : 17)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	P70313, O55056	Gene names	Nos3, Ecnos
Domain Architecture
Description	Nitric-oxide synthase, endothelial (EC 1.14.13.39) (EC-NOS) (NOS type III) (NOSIII) (Endothelial NOS) (eNOS) (Constitutive NOS) (cNOS).

TPR_HUMAN
NC score	0.006430 (rank : 18)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	1921	Shared Neighborhood Hits	7
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

RBBP6_HUMAN
NC score	0.006186 (rank : 19)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	1135	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

EVPL_HUMAN
NC score	0.005859 (rank : 20)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	895	Shared Neighborhood Hits	6
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

CROCC_MOUSE
NC score	0.005500 (rank : 21)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	1460	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

TBR1_MOUSE
NC score	0.005481 (rank : 22)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q64336	Gene names	Tbr1
Domain Architecture
Description	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56).