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Network neighborhood for query Sequence : PDP2_HUMAN

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PDP2_HUMAN
SwissProt Accessions	Q9P2J9	Gene names	PDP2, KIAA1348
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 2, mitochondrial precursor (EC 3.1.3.43) (PDP 2) (Pyruvate dehydrogenase phosphatase, catalytic subunit 2) (PDPC 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PDP2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	Q9P2J9	Gene names	PDP2, KIAA1348
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 2, mitochondrial precursor (EC 3.1.3.43) (PDP 2) (Pyruvate dehydrogenase phosphatase, catalytic subunit 2) (PDPC 2).

PDP1_HUMAN
θ value	5.59392e-143 (rank : 2)	NC score	0.968379 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q9P0J1, Q5U5K1	Gene names	PDP1, PDP, PPM2C
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 1, mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C).

PDP1_MOUSE
θ value	7.30591e-143 (rank : 3)	NC score	0.968718 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q3UV70	Gene names	Pdp1, Ppm2c
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 1, mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C).

PP2CL_HUMAN
θ value	3.29651e-10 (rank : 4)	NC score	0.555015 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	Q5SGD2, Q96NM7	Gene names	PPM1L, PP2CE
Domain Architecture	No domain graphic available
Description	Protein phosphatase 2C isoform epsilon (EC 3.1.3.16) (PP2C-epsilon) (Protein phosphatase 1L) (Protein phosphatase 1-like).

PP2CL_MOUSE
θ value	4.30538e-10 (rank : 5)	NC score	0.553577 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BHN0, Q3UGL2, Q810H0, Q8C021, Q8C1D5, Q9Z0T1	Gene names	Ppm1l, Kiaa4175
Domain Architecture	No domain graphic available
Description	Protein phosphatase 2C isoform epsilon (EC 3.1.3.16) (PP2C-epsilon) (Protein phosphatase 1L) (Protein phosphatase 1-like).

PP2CG_HUMAN
θ value	2.13673e-09 (rank : 6)	NC score	0.536245 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	140	Shared Neighborhood Hits	22
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

PP2CG_MOUSE
θ value	2.13673e-09 (rank : 7)	NC score	0.521440 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	185	Shared Neighborhood Hits	22
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

PP2CB_MOUSE
θ value	3.08544e-08 (rank : 8)	NC score	0.488469 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	28	Shared Neighborhood Hits	22
SwissProt Accessions	P36993	Gene names	Ppm1b, Pp2c2, Pppm1b
Domain Architecture
Description	Protein phosphatase 2C isoform beta (EC 3.1.3.16) (PP2C-beta) (IA) (Protein phosphatase 1B).

PP2CB_HUMAN
θ value	5.26297e-08 (rank : 9)	NC score	0.489943 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	21
SwissProt Accessions	O75688, Q9HAY8	Gene names	PPM1B, PP2CB
Domain Architecture
Description	Protein phosphatase 2C isoform beta (EC 3.1.3.16) (PP2C-beta).

PP2CD_HUMAN
θ value	3.41135e-07 (rank : 10)	NC score	0.490956 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	34	Shared Neighborhood Hits	16
SwissProt Accessions	O15297	Gene names	PPM1D, WIP1
Domain Architecture
Description	Protein phosphatase 2C isoform delta (EC 3.1.3.16) (PP2C-delta) (p53- induced protein phosphatase 1) (Protein phosphatase magnesium- dependent 1 delta).

PP2CE_MOUSE
θ value	5.81887e-07 (rank : 11)	NC score	0.461933 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BU27, Q9CSD6, Q9CU88	Gene names	Ppm1m, Ppm1e
Domain Architecture
Description	Protein phosphatase 2C isoform eta (EC 3.1.3.16) (PP2C-eta) (PP2CE) (Protein phosphatase 1M).

PP2CD_MOUSE
θ value	2.21117e-06 (rank : 12)	NC score	0.478030 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QZ67	Gene names	Ppm1d, Wip1
Domain Architecture
Description	Protein phosphatase 2C isoform delta (EC 3.1.3.16) (PP2C-delta) (p53- induced protein phosphatase 1) (Protein phosphatase magnesium- dependent 1 delta).

PPM1F_MOUSE
θ value	2.88788e-06 (rank : 13)	NC score	0.453073 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CGA0	Gene names	Ppm1f
Domain Architecture	No domain graphic available
Description	Ca(2+)/calmodulin-dependent protein kinase phosphatase (EC 3.1.3.16) (CaM-kinase phosphatase) (CaMKPase) (Protein phosphatase 1F).

PP2CA_HUMAN
θ value	3.19293e-05 (rank : 14)	NC score	0.461708 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	P35813, O75551	Gene names	PPM1A, PPPM1A
Domain Architecture
Description	Protein phosphatase 2C isoform alpha (EC 3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A).

PP2CA_MOUSE
θ value	3.19293e-05 (rank : 15)	NC score	0.461019 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	23	Shared Neighborhood Hits	20
SwissProt Accessions	P49443	Gene names	Ppm1a, Pppm1a
Domain Architecture
Description	Protein phosphatase 2C isoform alpha (EC 3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A).

PPM1F_HUMAN
θ value	0.000270298 (rank : 16)	NC score	0.459216 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	31	Shared Neighborhood Hits	19
SwissProt Accessions	P49593, Q96PM2	Gene names	PPM1F, KIAA0015, POPX2
Domain Architecture
Description	Ca(2+)/calmodulin-dependent protein kinase phosphatase (EC 3.1.3.16) (CaM-kinase phosphatase) (CaMKPase) (Partner of PIX 2) (hFEM-2) (Protein phosphatase 1F).

PHLPP_HUMAN
θ value	0.00035302 (rank : 17)	NC score	0.126269 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	604	Shared Neighborhood Hits	16
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PHLPP_MOUSE
θ value	0.00509761 (rank : 18)	NC score	0.124559 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	394	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

TAB1_MOUSE
θ value	0.0193708 (rank : 19)	NC score	0.228271 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CF89, Q7TQJ5, Q80V65, Q8R0D1	Gene names	Map3k7ip1, Tab1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 1 (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1).

PP2CE_HUMAN
θ value	0.0252991 (rank : 20)	NC score	0.385328 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	17	Shared Neighborhood Hits	16
SwissProt Accessions	Q96MI6, Q8N8J9, Q96DB8	Gene names	PPM1M, PPM1E
Domain Architecture
Description	Protein phosphatase 2C isoform eta (EC 3.1.3.16) (PP2C-eta) (PP2CE) (Protein phosphatase 1M).

KCC1A_HUMAN
θ value	0.0431538 (rank : 21)	NC score	0.009457 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	846	Shared Neighborhood Hits	3
SwissProt Accessions	Q14012	Gene names	CAMK1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

KCC1A_MOUSE
θ value	0.0563607 (rank : 22)	NC score	0.009181 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	845	Shared Neighborhood Hits	3
SwissProt Accessions	Q91YS8	Gene names	Camk1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

PHLPL_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.101308 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	310	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZVD8, Q9NV17, Q9Y2E3	Gene names	PHLPPL, KIAA0931
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

UGGG1_MOUSE
θ value	2.36792 (rank : 24)	NC score	0.027752 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P5E4, Q6NV70	Gene names	Ugcgl1, Gt, Uggt, Ugt1, Ugtr
Domain Architecture	No domain graphic available
Description	UDP-glucose:glycoprotein glucosyltransferase 1 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase).

BID_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.032850 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	P55957, Q549M7, Q71T04, Q7Z4M9, Q8IY86	Gene names	BID
Domain Architecture
Description	BH3-interacting domain death agonist (BID) (p22 BID) [Contains: BH3- interacting domain death agonist p15 (p15 BID); BH3-interacting domain death agonist p13 (p13 BID); BH3-interacting domain death agonist p11 (p11 BID)].

PHLPL_MOUSE
θ value	5.27518 (rank : 26)	NC score	0.097340 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	303	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BXA7, Q8BX96	Gene names	Phlppl
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

BGLR_MOUSE
θ value	6.88961 (rank : 27)	NC score	0.014682 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P12265, Q61601, Q64473, Q64474	Gene names	Gusb, Gus, Gus-s
Domain Architecture
Description	Beta-glucuronidase precursor (EC 3.2.1.31).

CCD46_MOUSE
θ value	6.88961 (rank : 28)	NC score	0.000525 (rank : 31)
Query Neighborhood Hits	30	Target Neighborhood Hits	1405	Shared Neighborhood Hits	3
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

SPTA1_MOUSE
θ value	6.88961 (rank : 29)	NC score	0.008340 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	675	Shared Neighborhood Hits	5
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

UGGG1_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.023815 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYU2, Q8IW30, Q9H8I4	Gene names	UGCGL1, GT, UGGT, UGT1, UGTR
Domain Architecture	No domain graphic available
Description	UDP-glucose:glycoprotein glucosyltransferase 1 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase) (HUGT1).

TAB1_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.182075 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	12
SwissProt Accessions	Q15750, Q2PP09	Gene names	MAP3K7IP1, TAB1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 1 (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1).

Hits sorted by NC score

PDP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	Q9P2J9	Gene names	PDP2, KIAA1348
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 2, mitochondrial precursor (EC 3.1.3.43) (PDP 2) (Pyruvate dehydrogenase phosphatase, catalytic subunit 2) (PDPC 2).

PDP1_MOUSE
NC score	0.968718 (rank : 2)	θ value	7.30591e-143 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q3UV70	Gene names	Pdp1, Ppm2c
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 1, mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C).

PDP1_HUMAN
NC score	0.968379 (rank : 3)	θ value	5.59392e-143 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q9P0J1, Q5U5K1	Gene names	PDP1, PDP, PPM2C
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 1, mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C).

PP2CL_HUMAN
NC score	0.555015 (rank : 4)	θ value	3.29651e-10 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	Q5SGD2, Q96NM7	Gene names	PPM1L, PP2CE
Domain Architecture	No domain graphic available
Description	Protein phosphatase 2C isoform epsilon (EC 3.1.3.16) (PP2C-epsilon) (Protein phosphatase 1L) (Protein phosphatase 1-like).

PP2CL_MOUSE
NC score	0.553577 (rank : 5)	θ value	4.30538e-10 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BHN0, Q3UGL2, Q810H0, Q8C021, Q8C1D5, Q9Z0T1	Gene names	Ppm1l, Kiaa4175
Domain Architecture	No domain graphic available
Description	Protein phosphatase 2C isoform epsilon (EC 3.1.3.16) (PP2C-epsilon) (Protein phosphatase 1L) (Protein phosphatase 1-like).

PP2CG_HUMAN
NC score	0.536245 (rank : 6)	θ value	2.13673e-09 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	140	Shared Neighborhood Hits	22
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

PP2CG_MOUSE
NC score	0.521440 (rank : 7)	θ value	2.13673e-09 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	185	Shared Neighborhood Hits	22
SwissProt Accessions	Q61074	Gene names	Ppm1g, Fin13, Ppm1c
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C) (Fibroblast growth factor-inducible protein 13) (FIN13).

PP2CD_HUMAN
NC score	0.490956 (rank : 8)	θ value	3.41135e-07 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	34	Shared Neighborhood Hits	16
SwissProt Accessions	O15297	Gene names	PPM1D, WIP1
Domain Architecture
Description	Protein phosphatase 2C isoform delta (EC 3.1.3.16) (PP2C-delta) (p53- induced protein phosphatase 1) (Protein phosphatase magnesium- dependent 1 delta).

PP2CB_HUMAN
NC score	0.489943 (rank : 9)	θ value	5.26297e-08 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	21
SwissProt Accessions	O75688, Q9HAY8	Gene names	PPM1B, PP2CB
Domain Architecture
Description	Protein phosphatase 2C isoform beta (EC 3.1.3.16) (PP2C-beta).

PP2CB_MOUSE
NC score	0.488469 (rank : 10)	θ value	3.08544e-08 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	28	Shared Neighborhood Hits	22
SwissProt Accessions	P36993	Gene names	Ppm1b, Pp2c2, Pppm1b
Domain Architecture
Description	Protein phosphatase 2C isoform beta (EC 3.1.3.16) (PP2C-beta) (IA) (Protein phosphatase 1B).

PP2CD_MOUSE
NC score	0.478030 (rank : 11)	θ value	2.21117e-06 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QZ67	Gene names	Ppm1d, Wip1
Domain Architecture
Description	Protein phosphatase 2C isoform delta (EC 3.1.3.16) (PP2C-delta) (p53- induced protein phosphatase 1) (Protein phosphatase magnesium- dependent 1 delta).

PP2CE_MOUSE
NC score	0.461933 (rank : 12)	θ value	5.81887e-07 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BU27, Q9CSD6, Q9CU88	Gene names	Ppm1m, Ppm1e
Domain Architecture
Description	Protein phosphatase 2C isoform eta (EC 3.1.3.16) (PP2C-eta) (PP2CE) (Protein phosphatase 1M).

PP2CA_HUMAN
NC score	0.461708 (rank : 13)	θ value	3.19293e-05 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	P35813, O75551	Gene names	PPM1A, PPPM1A
Domain Architecture
Description	Protein phosphatase 2C isoform alpha (EC 3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A).

PP2CA_MOUSE
NC score	0.461019 (rank : 14)	θ value	3.19293e-05 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	23	Shared Neighborhood Hits	20
SwissProt Accessions	P49443	Gene names	Ppm1a, Pppm1a
Domain Architecture
Description	Protein phosphatase 2C isoform alpha (EC 3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A).

PPM1F_HUMAN
NC score	0.459216 (rank : 15)	θ value	0.000270298 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	31	Shared Neighborhood Hits	19
SwissProt Accessions	P49593, Q96PM2	Gene names	PPM1F, KIAA0015, POPX2
Domain Architecture
Description	Ca(2+)/calmodulin-dependent protein kinase phosphatase (EC 3.1.3.16) (CaM-kinase phosphatase) (CaMKPase) (Partner of PIX 2) (hFEM-2) (Protein phosphatase 1F).

PPM1F_MOUSE
NC score	0.453073 (rank : 16)	θ value	2.88788e-06 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CGA0	Gene names	Ppm1f
Domain Architecture	No domain graphic available
Description	Ca(2+)/calmodulin-dependent protein kinase phosphatase (EC 3.1.3.16) (CaM-kinase phosphatase) (CaMKPase) (Protein phosphatase 1F).

PP2CE_HUMAN
NC score	0.385328 (rank : 17)	θ value	0.0252991 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	17	Shared Neighborhood Hits	16
SwissProt Accessions	Q96MI6, Q8N8J9, Q96DB8	Gene names	PPM1M, PPM1E
Domain Architecture
Description	Protein phosphatase 2C isoform eta (EC 3.1.3.16) (PP2C-eta) (PP2CE) (Protein phosphatase 1M).

TAB1_MOUSE
NC score	0.228271 (rank : 18)	θ value	0.0193708 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CF89, Q7TQJ5, Q80V65, Q8R0D1	Gene names	Map3k7ip1, Tab1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 1 (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1).

TAB1_HUMAN
NC score	0.182075 (rank : 19)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	12
SwissProt Accessions	Q15750, Q2PP09	Gene names	MAP3K7IP1, TAB1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 1 (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1).

PHLPP_HUMAN
NC score	0.126269 (rank : 20)	θ value	0.00035302 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	604	Shared Neighborhood Hits	16
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PHLPP_MOUSE
NC score	0.124559 (rank : 21)	θ value	0.00509761 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	394	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

PHLPL_HUMAN
NC score	0.101308 (rank : 22)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	310	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZVD8, Q9NV17, Q9Y2E3	Gene names	PHLPPL, KIAA0931
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

PHLPL_MOUSE
NC score	0.097340 (rank : 23)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	303	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BXA7, Q8BX96	Gene names	Phlppl
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

BID_HUMAN
NC score	0.032850 (rank : 24)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	P55957, Q549M7, Q71T04, Q7Z4M9, Q8IY86	Gene names	BID
Domain Architecture
Description	BH3-interacting domain death agonist (BID) (p22 BID) [Contains: BH3- interacting domain death agonist p15 (p15 BID); BH3-interacting domain death agonist p13 (p13 BID); BH3-interacting domain death agonist p11 (p11 BID)].

UGGG1_MOUSE
NC score	0.027752 (rank : 25)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P5E4, Q6NV70	Gene names	Ugcgl1, Gt, Uggt, Ugt1, Ugtr
Domain Architecture	No domain graphic available
Description	UDP-glucose:glycoprotein glucosyltransferase 1 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase).

UGGG1_HUMAN
NC score	0.023815 (rank : 26)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYU2, Q8IW30, Q9H8I4	Gene names	UGCGL1, GT, UGGT, UGT1, UGTR
Domain Architecture	No domain graphic available
Description	UDP-glucose:glycoprotein glucosyltransferase 1 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase) (HUGT1).

BGLR_MOUSE
NC score	0.014682 (rank : 27)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P12265, Q61601, Q64473, Q64474	Gene names	Gusb, Gus, Gus-s
Domain Architecture
Description	Beta-glucuronidase precursor (EC 3.2.1.31).

KCC1A_HUMAN
NC score	0.009457 (rank : 28)	θ value	0.0431538 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	846	Shared Neighborhood Hits	3
SwissProt Accessions	Q14012	Gene names	CAMK1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

KCC1A_MOUSE
NC score	0.009181 (rank : 29)	θ value	0.0563607 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	845	Shared Neighborhood Hits	3
SwissProt Accessions	Q91YS8	Gene names	Camk1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

SPTA1_MOUSE
NC score	0.008340 (rank : 30)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	675	Shared Neighborhood Hits	5
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

CCD46_MOUSE
NC score	0.000525 (rank : 31)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	1405	Shared Neighborhood Hits	3
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.