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Network neighborhood for query Sequence : HSP71_HUMAN

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HSP71_HUMAN
SwissProt Accessions	P08107, P19790, Q9UQL9, Q9UQM0	Gene names	HSPA1A, HSPA1
Domain Architecture
Description	Heat shock 70 kDa protein 1 (HSP70.1) (HSP70-1/HSP70-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GRP78_HUMAN
θ value	0 (rank : 1)	NC score	0.982740 (rank : 12)
Query Neighborhood Hits	87	Target Neighborhood Hits	218	Shared Neighborhood Hits	46
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
θ value	0 (rank : 2)	NC score	0.982634 (rank : 13)
Query Neighborhood Hits	87	Target Neighborhood Hits	216	Shared Neighborhood Hits	46
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

HS70A_MOUSE
θ value	0 (rank : 3)	NC score	0.998478 (rank : 3)
Query Neighborhood Hits	87	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	Q61696, Q61697, Q7TQD8, Q9QWJ5	Gene names	Hspa1a, Hsp70-3, Hsp70A1
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 3) (HSP70.3) (Hsp68).

HS70B_MOUSE
θ value	0 (rank : 4)	NC score	0.998510 (rank : 2)
Query Neighborhood Hits	87	Target Neighborhood Hits	72	Shared Neighborhood Hits	63
SwissProt Accessions	P17879, Q61689, Q925V6	Gene names	Hspa1b, Hcp70.1, Hsp70-1, Hsp70a1, Hspa1
Domain Architecture
Description	Heat shock 70 kDa protein 1B (HSP70.1).

HS70L_HUMAN
θ value	0 (rank : 5)	NC score	0.996905 (rank : 5)
Query Neighborhood Hits	87	Target Neighborhood Hits	50	Shared Neighborhood Hits	37
SwissProt Accessions	P34931, O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1	Gene names	HSPA1L
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom).

HS70L_MOUSE
θ value	0 (rank : 6)	NC score	0.997053 (rank : 4)
Query Neighborhood Hits	87	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	P16627, O88686, Q61693	Gene names	Hspa1l, Hsc70t
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa-like protein 1) (Spermatid-specific heat shock protein 70).

HSP71_HUMAN
θ value	0 (rank : 7)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	87	Target Neighborhood Hits	87	Shared Neighborhood Hits	87
SwissProt Accessions	P08107, P19790, Q9UQL9, Q9UQM0	Gene names	HSPA1A, HSPA1
Domain Architecture
Description	Heat shock 70 kDa protein 1 (HSP70.1) (HSP70-1/HSP70-2).

HSP72_HUMAN
θ value	0 (rank : 8)	NC score	0.996319 (rank : 6)
Query Neighborhood Hits	87	Target Neighborhood Hits	85	Shared Neighborhood Hits	50
SwissProt Accessions	P54652, Q15508, Q9UE78	Gene names	HSPA2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2).

HSP72_MOUSE
θ value	0 (rank : 9)	NC score	0.996185 (rank : 7)
Query Neighborhood Hits	87	Target Neighborhood Hits	83	Shared Neighborhood Hits	46
SwissProt Accessions	P17156	Gene names	Hspa2, Hcp70.2, Hsp70-2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock protein 70.2).

HSP76_HUMAN
θ value	0 (rank : 10)	NC score	0.995220 (rank : 8)
Query Neighborhood Hits	87	Target Neighborhood Hits	128	Shared Neighborhood Hits	53
SwissProt Accessions	P17066, Q8IYK7, Q9BT95	Gene names	HSPA6, HSP70B'
Domain Architecture
Description	Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B').

HSP7C_HUMAN
θ value	0 (rank : 11)	NC score	0.993481 (rank : 9)
Query Neighborhood Hits	87	Target Neighborhood Hits	150	Shared Neighborhood Hits	54
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP7C_MOUSE
θ value	0 (rank : 12)	NC score	0.992828 (rank : 10)
Query Neighborhood Hits	87	Target Neighborhood Hits	166	Shared Neighborhood Hits	56
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

GRP75_HUMAN
θ value	3.99958e-149 (rank : 13)	NC score	0.982377 (rank : 14)
Query Neighborhood Hits	87	Target Neighborhood Hits	97	Shared Neighborhood Hits	35
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

GRP75_MOUSE
θ value	5.77539e-148 (rank : 14)	NC score	0.983171 (rank : 11)
Query Neighborhood Hits	87	Target Neighborhood Hits	88	Shared Neighborhood Hits	32
SwissProt Accessions	P38647, Q9CQ05	Gene names	Hspa9a, Grp75, Hsp74, Hspa9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (P66 MOT) (Mortalin).

HSP74_MOUSE
θ value	1.31376e-75 (rank : 15)	NC score	0.891035 (rank : 22)
Query Neighborhood Hits	87	Target Neighborhood Hits	257	Shared Neighborhood Hits	40
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

HS74L_MOUSE
θ value	2.24094e-75 (rank : 16)	NC score	0.902715 (rank : 18)
Query Neighborhood Hits	87	Target Neighborhood Hits	141	Shared Neighborhood Hits	31
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HSP74_HUMAN
θ value	2.92676e-75 (rank : 17)	NC score	0.902349 (rank : 19)
Query Neighborhood Hits	87	Target Neighborhood Hits	154	Shared Neighborhood Hits	34
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

STCH_HUMAN
θ value	1.45253e-74 (rank : 18)	NC score	0.963734 (rank : 15)
Query Neighborhood Hits	87	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	P48723, Q8NE40	Gene names	STCH
Domain Architecture
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

HS74L_HUMAN
θ value	1.89707e-74 (rank : 19)	NC score	0.901159 (rank : 20)
Query Neighborhood Hits	87	Target Neighborhood Hits	141	Shared Neighborhood Hits	37
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

STCH_MOUSE
θ value	5.51964e-74 (rank : 20)	NC score	0.963314 (rank : 16)
Query Neighborhood Hits	87	Target Neighborhood Hits	39	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BM72, Q3TII6, Q9D1X5	Gene names	Stch
Domain Architecture	No domain graphic available
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

HS105_HUMAN
θ value	6.7473e-72 (rank : 21)	NC score	0.898190 (rank : 21)
Query Neighborhood Hits	87	Target Neighborhood Hits	209	Shared Neighborhood Hits	30
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

HS105_MOUSE
θ value	8.81223e-72 (rank : 22)	NC score	0.905509 (rank : 17)
Query Neighborhood Hits	87	Target Neighborhood Hits	129	Shared Neighborhood Hits	32
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

OXRP_HUMAN
θ value	8.28633e-54 (rank : 23)	NC score	0.874642 (rank : 23)
Query Neighborhood Hits	87	Target Neighborhood Hits	544	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

ANR45_HUMAN
θ value	0.000602161 (rank : 24)	NC score	0.248680 (rank : 24)
Query Neighborhood Hits	87	Target Neighborhood Hits	201	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

HS12B_MOUSE
θ value	0.00390308 (rank : 25)	NC score	0.145540 (rank : 26)
Query Neighborhood Hits	87	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CZJ2	Gene names	Hspa12b
Domain Architecture
Description	Heat shock 70 kDa protein 12B.

HS12B_HUMAN
θ value	0.0330416 (rank : 26)	NC score	0.091251 (rank : 27)
Query Neighborhood Hits	87	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	Q96MM6, Q9BR52	Gene names	HSPA12B, C20orf60
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 12B.

MYH9_MOUSE
θ value	0.0431538 (rank : 27)	NC score	0.042743 (rank : 40)
Query Neighborhood Hits	87	Target Neighborhood Hits	1829	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

GOGB1_HUMAN
θ value	0.0563607 (rank : 28)	NC score	0.039081 (rank : 43)
Query Neighborhood Hits	87	Target Neighborhood Hits	2297	Shared Neighborhood Hits	64
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MYH11_HUMAN
θ value	0.0563607 (rank : 29)	NC score	0.048769 (rank : 34)
Query Neighborhood Hits	87	Target Neighborhood Hits	1806	Shared Neighborhood Hits	65
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_HUMAN
θ value	0.0736092 (rank : 30)	NC score	0.044220 (rank : 39)
Query Neighborhood Hits	87	Target Neighborhood Hits	1762	Shared Neighborhood Hits	65
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

LAMB1_MOUSE
θ value	0.0961366 (rank : 31)	NC score	0.028347 (rank : 58)
Query Neighborhood Hits	87	Target Neighborhood Hits	919	Shared Neighborhood Hits	34
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MYH10_HUMAN
θ value	0.0961366 (rank : 32)	NC score	0.045221 (rank : 37)
Query Neighborhood Hits	87	Target Neighborhood Hits	1620	Shared Neighborhood Hits	62
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	0.0961366 (rank : 33)	NC score	0.044730 (rank : 38)
Query Neighborhood Hits	87	Target Neighborhood Hits	1612	Shared Neighborhood Hits	61
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

ANR45_MOUSE
θ value	0.163984 (rank : 34)	NC score	0.189549 (rank : 25)
Query Neighborhood Hits	87	Target Neighborhood Hits	204	Shared Neighborhood Hits	14
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

U2AFM_HUMAN
θ value	0.163984 (rank : 35)	NC score	0.034738 (rank : 46)
Query Neighborhood Hits	87	Target Neighborhood Hits	577	Shared Neighborhood Hits	33
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

CENPJ_HUMAN
θ value	0.365318 (rank : 36)	NC score	0.036169 (rank : 45)
Query Neighborhood Hits	87	Target Neighborhood Hits	721	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

FA44A_HUMAN
θ value	0.47712 (rank : 37)	NC score	0.060029 (rank : 29)
Query Neighborhood Hits	87	Target Neighborhood Hits	280	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

MYH11_MOUSE
θ value	0.47712 (rank : 38)	NC score	0.041633 (rank : 41)
Query Neighborhood Hits	87	Target Neighborhood Hits	1777	Shared Neighborhood Hits	60
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

BPAEA_MOUSE
θ value	0.62314 (rank : 39)	NC score	0.030313 (rank : 54)
Query Neighborhood Hits	87	Target Neighborhood Hits	1480	Shared Neighborhood Hits	56
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CENPU_HUMAN
θ value	0.62314 (rank : 40)	NC score	0.046926 (rank : 35)
Query Neighborhood Hits	87	Target Neighborhood Hits	289	Shared Neighborhood Hits	26
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

GOGA4_HUMAN
θ value	0.813845 (rank : 41)	NC score	0.029766 (rank : 55)
Query Neighborhood Hits	87	Target Neighborhood Hits	2034	Shared Neighborhood Hits	62
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

K2C3_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.020052 (rank : 74)
Query Neighborhood Hits	87	Target Neighborhood Hits	443	Shared Neighborhood Hits	39
SwissProt Accessions	P12035, Q701L8	Gene names	KRT3
Domain Architecture
Description	Keratin, type II cytoskeletal 3 (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (65 kDa cytokeratin).

MYO6_MOUSE
θ value	0.813845 (rank : 43)	NC score	0.028211 (rank : 59)
Query Neighborhood Hits	87	Target Neighborhood Hits	586	Shared Neighborhood Hits	33
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

BRE1B_HUMAN
θ value	1.06291 (rank : 44)	NC score	0.024317 (rank : 70)
Query Neighborhood Hits	87	Target Neighborhood Hits	1040	Shared Neighborhood Hits	38
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	1.06291 (rank : 45)	NC score	0.025035 (rank : 66)
Query Neighborhood Hits	87	Target Neighborhood Hits	970	Shared Neighborhood Hits	40
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

KNTC2_HUMAN
θ value	1.06291 (rank : 46)	NC score	0.017728 (rank : 77)
Query Neighborhood Hits	87	Target Neighborhood Hits	673	Shared Neighborhood Hits	36
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

DZIP3_MOUSE
θ value	1.38821 (rank : 47)	NC score	0.020556 (rank : 73)
Query Neighborhood Hits	87	Target Neighborhood Hits	414	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

DYXC1_HUMAN
θ value	1.81305 (rank : 48)	NC score	0.046658 (rank : 36)
Query Neighborhood Hits	87	Target Neighborhood Hits	261	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

FLNA_HUMAN
θ value	1.81305 (rank : 49)	NC score	0.026892 (rank : 62)
Query Neighborhood Hits	87	Target Neighborhood Hits	138	Shared Neighborhood Hits	12
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

MYO6_HUMAN
θ value	1.81305 (rank : 50)	NC score	0.031410 (rank : 53)
Query Neighborhood Hits	87	Target Neighborhood Hits	727	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

TNNT2_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.033617 (rank : 48)
Query Neighborhood Hits	87	Target Neighborhood Hits	433	Shared Neighborhood Hits	32
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

3BP5_MOUSE
θ value	2.36792 (rank : 52)	NC score	0.024488 (rank : 68)
Query Neighborhood Hits	87	Target Neighborhood Hits	346	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z131, Q8C903, Q8VCZ0	Gene names	Sh3bp5, Sab
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

DYH5_MOUSE
θ value	2.36792 (rank : 53)	NC score	0.027777 (rank : 61)
Query Neighborhood Hits	87	Target Neighborhood Hits	286	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

EEA1_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.021716 (rank : 72)
Query Neighborhood Hits	87	Target Neighborhood Hits	1796	Shared Neighborhood Hits	55
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

3BP5_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.024759 (rank : 67)
Query Neighborhood Hits	87	Target Neighborhood Hits	375	Shared Neighborhood Hits	29
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

DYH5_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.028585 (rank : 57)
Query Neighborhood Hits	87	Target Neighborhood Hits	323	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

MY18B_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.024389 (rank : 69)
Query Neighborhood Hits	87	Target Neighborhood Hits	1299	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

NUMA1_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.014718 (rank : 83)
Query Neighborhood Hits	87	Target Neighborhood Hits	1523	Shared Neighborhood Hits	46
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

MYH14_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.033954 (rank : 47)
Query Neighborhood Hits	87	Target Neighborhood Hits	1225	Shared Neighborhood Hits	56
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

UBXD2_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.036365 (rank : 44)
Query Neighborhood Hits	87	Target Neighborhood Hits	241	Shared Neighborhood Hits	20
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

UBXD2_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.033498 (rank : 49)
Query Neighborhood Hits	87	Target Neighborhood Hits	183	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VCH8, Q8BW17	Gene names	Ubxd2, Ubxdc1
Domain Architecture
Description	UBX domain-containing protein 2.

CENPF_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.031530 (rank : 52)
Query Neighborhood Hits	87	Target Neighborhood Hits	1932	Shared Neighborhood Hits	56
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CLUS_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.017169 (rank : 78)
Query Neighborhood Hits	87	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	P10909, P11380, P11381, Q7Z5B9	Gene names	CLU
Domain Architecture
Description	Clusterin precursor (Complement-associated protein SP-40,40) (Complement cytolysis inhibitor) (CLI) (NA1/NA2) (Apolipoprotein J) (Apo-J) (Testosterone-repressed prostate message 2) (TRPM-2) [Contains: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain)].

FLNA_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.022346 (rank : 71)
Query Neighborhood Hits	87	Target Neighborhood Hits	142	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

K2C7_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.012801 (rank : 85)
Query Neighborhood Hits	87	Target Neighborhood Hits	369	Shared Neighborhood Hits	34
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

LRC8E_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.000533 (rank : 90)
Query Neighborhood Hits	87	Target Neighborhood Hits	256	Shared Neighborhood Hits	2
SwissProt Accessions	Q66JT1	Gene names	Lrrc8e
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8E.

MYH6_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.029699 (rank : 56)
Query Neighborhood Hits	87	Target Neighborhood Hits	1426	Shared Neighborhood Hits	56
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

PCIF1_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.049903 (rank : 33)
Query Neighborhood Hits	87	Target Neighborhood Hits	92	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

PDP1_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.019971 (rank : 75)
Query Neighborhood Hits	87	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P0J1, Q5U5K1	Gene names	PDP1, PDP, PPM2C
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 1, mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C).

PDP1_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.019893 (rank : 76)
Query Neighborhood Hits	87	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q3UV70	Gene names	Pdp1, Ppm2c
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 1, mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C).

SMC4_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.026385 (rank : 63)
Query Neighborhood Hits	87	Target Neighborhood Hits	937	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

TNNT2_MOUSE
θ value	5.27518 (rank : 72)	NC score	0.027820 (rank : 60)
Query Neighborhood Hits	87	Target Neighborhood Hits	395	Shared Neighborhood Hits	29
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

K2C1_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.013632 (rank : 84)
Query Neighborhood Hits	87	Target Neighborhood Hits	624	Shared Neighborhood Hits	43
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

MYH3_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.025237 (rank : 65)
Query Neighborhood Hits	87	Target Neighborhood Hits	1660	Shared Neighborhood Hits	56
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH6_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.032380 (rank : 51)
Query Neighborhood Hits	87	Target Neighborhood Hits	1501	Shared Neighborhood Hits	58
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.033078 (rank : 50)
Query Neighborhood Hits	87	Target Neighborhood Hits	1559	Shared Neighborhood Hits	57
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

NDE1_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.016242 (rank : 79)
Query Neighborhood Hits	87	Target Neighborhood Hits	823	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

PCIF1_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.041364 (rank : 42)
Query Neighborhood Hits	87	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	P59114	Gene names	Pcif1
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

REST_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.025580 (rank : 64)
Query Neighborhood Hits	87	Target Neighborhood Hits	1605	Shared Neighborhood Hits	58
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ANR26_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.015507 (rank : 82)
Query Neighborhood Hits	87	Target Neighborhood Hits	1614	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

APOL2_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.009962 (rank : 86)
Query Neighborhood Hits	87	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQE5, O95915, Q5TH96, Q969T6, Q9BT28, Q9UGT1, Q9UH10	Gene names	APOL2
Domain Architecture
Description	Apolipoprotein-L2 (Apolipoprotein L-II) (ApoL-II).

CAF1A_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.058644 (rank : 30)
Query Neighborhood Hits	87	Target Neighborhood Hits	750	Shared Neighborhood Hits	42
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CI039_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.015655 (rank : 81)
Query Neighborhood Hits	87	Target Neighborhood Hits	1171	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

IF4G3_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.004278 (rank : 89)
Query Neighborhood Hits	87	Target Neighborhood Hits	247	Shared Neighborhood Hits	12
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

K2C6G_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.008704 (rank : 88)
Query Neighborhood Hits	87	Target Neighborhood Hits	452	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R0H5, Q7TPF3, Q9D0X6	Gene names	Krt6g, K6irs1, Krt2-6g
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6G (Cytokeratin-6G) (CK 6G) (K6g keratin) (Keratin-K6irs) (mK6irs1/Krt2-6g).

NDE1_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.015813 (rank : 80)
Query Neighborhood Hits	87	Target Neighborhood Hits	602	Shared Neighborhood Hits	37
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

PWP1_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.009016 (rank : 87)
Query Neighborhood Hits	87	Target Neighborhood Hits	278	Shared Neighborhood Hits	4
SwissProt Accessions	Q99LL5, Q9D6T6	Gene names	Pwp1
Domain Architecture	No domain graphic available
Description	Periodic tryptophan protein 1 homolog.

COVA1_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.054730 (rank : 31)
Query Neighborhood Hits	87	Target Neighborhood Hits	416	Shared Neighborhood Hits	35
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

SFR12_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.062288 (rank : 28)
Query Neighborhood Hits	87	Target Neighborhood Hits	553	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SFR12_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.050455 (rank : 32)
Query Neighborhood Hits	87	Target Neighborhood Hits	486	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

Hits sorted by NC score

HSP71_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 7)
Query Neighborhood Hits	87	Target Neighborhood Hits	87	Shared Neighborhood Hits	87
SwissProt Accessions	P08107, P19790, Q9UQL9, Q9UQM0	Gene names	HSPA1A, HSPA1
Domain Architecture
Description	Heat shock 70 kDa protein 1 (HSP70.1) (HSP70-1/HSP70-2).

HS70B_MOUSE
NC score	0.998510 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	87	Target Neighborhood Hits	72	Shared Neighborhood Hits	63
SwissProt Accessions	P17879, Q61689, Q925V6	Gene names	Hspa1b, Hcp70.1, Hsp70-1, Hsp70a1, Hspa1
Domain Architecture
Description	Heat shock 70 kDa protein 1B (HSP70.1).

HS70A_MOUSE
NC score	0.998478 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	87	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	Q61696, Q61697, Q7TQD8, Q9QWJ5	Gene names	Hspa1a, Hsp70-3, Hsp70A1
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 3) (HSP70.3) (Hsp68).

HS70L_MOUSE
NC score	0.997053 (rank : 4)	θ value	0 (rank : 6)
Query Neighborhood Hits	87	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	P16627, O88686, Q61693	Gene names	Hspa1l, Hsc70t
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa-like protein 1) (Spermatid-specific heat shock protein 70).

HS70L_HUMAN
NC score	0.996905 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	87	Target Neighborhood Hits	50	Shared Neighborhood Hits	37
SwissProt Accessions	P34931, O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1	Gene names	HSPA1L
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom).

HSP72_HUMAN
NC score	0.996319 (rank : 6)	θ value	0 (rank : 8)
Query Neighborhood Hits	87	Target Neighborhood Hits	85	Shared Neighborhood Hits	50
SwissProt Accessions	P54652, Q15508, Q9UE78	Gene names	HSPA2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2).

HSP72_MOUSE
NC score	0.996185 (rank : 7)	θ value	0 (rank : 9)
Query Neighborhood Hits	87	Target Neighborhood Hits	83	Shared Neighborhood Hits	46
SwissProt Accessions	P17156	Gene names	Hspa2, Hcp70.2, Hsp70-2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock protein 70.2).

HSP76_HUMAN
NC score	0.995220 (rank : 8)	θ value	0 (rank : 10)
Query Neighborhood Hits	87	Target Neighborhood Hits	128	Shared Neighborhood Hits	53
SwissProt Accessions	P17066, Q8IYK7, Q9BT95	Gene names	HSPA6, HSP70B'
Domain Architecture
Description	Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B').

HSP7C_HUMAN
NC score	0.993481 (rank : 9)	θ value	0 (rank : 11)
Query Neighborhood Hits	87	Target Neighborhood Hits	150	Shared Neighborhood Hits	54
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP7C_MOUSE
NC score	0.992828 (rank : 10)	θ value	0 (rank : 12)
Query Neighborhood Hits	87	Target Neighborhood Hits	166	Shared Neighborhood Hits	56
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

GRP75_MOUSE
NC score	0.983171 (rank : 11)	θ value	5.77539e-148 (rank : 14)
Query Neighborhood Hits	87	Target Neighborhood Hits	88	Shared Neighborhood Hits	32
SwissProt Accessions	P38647, Q9CQ05	Gene names	Hspa9a, Grp75, Hsp74, Hspa9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (P66 MOT) (Mortalin).

GRP78_HUMAN
NC score	0.982740 (rank : 12)	θ value	0 (rank : 1)
Query Neighborhood Hits	87	Target Neighborhood Hits	218	Shared Neighborhood Hits	46
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
NC score	0.982634 (rank : 13)	θ value	0 (rank : 2)
Query Neighborhood Hits	87	Target Neighborhood Hits	216	Shared Neighborhood Hits	46
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

GRP75_HUMAN
NC score	0.982377 (rank : 14)	θ value	3.99958e-149 (rank : 13)
Query Neighborhood Hits	87	Target Neighborhood Hits	97	Shared Neighborhood Hits	35
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

STCH_HUMAN
NC score	0.963734 (rank : 15)	θ value	1.45253e-74 (rank : 18)
Query Neighborhood Hits	87	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	P48723, Q8NE40	Gene names	STCH
Domain Architecture
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

STCH_MOUSE
NC score	0.963314 (rank : 16)	θ value	5.51964e-74 (rank : 20)
Query Neighborhood Hits	87	Target Neighborhood Hits	39	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BM72, Q3TII6, Q9D1X5	Gene names	Stch
Domain Architecture	No domain graphic available
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

HS105_MOUSE
NC score	0.905509 (rank : 17)	θ value	8.81223e-72 (rank : 22)
Query Neighborhood Hits	87	Target Neighborhood Hits	129	Shared Neighborhood Hits	32
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

HS74L_MOUSE
NC score	0.902715 (rank : 18)	θ value	2.24094e-75 (rank : 16)
Query Neighborhood Hits	87	Target Neighborhood Hits	141	Shared Neighborhood Hits	31
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HSP74_HUMAN
NC score	0.902349 (rank : 19)	θ value	2.92676e-75 (rank : 17)
Query Neighborhood Hits	87	Target Neighborhood Hits	154	Shared Neighborhood Hits	34
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

HS74L_HUMAN
NC score	0.901159 (rank : 20)	θ value	1.89707e-74 (rank : 19)
Query Neighborhood Hits	87	Target Neighborhood Hits	141	Shared Neighborhood Hits	37
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HS105_HUMAN
NC score	0.898190 (rank : 21)	θ value	6.7473e-72 (rank : 21)
Query Neighborhood Hits	87	Target Neighborhood Hits	209	Shared Neighborhood Hits	30
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

HSP74_MOUSE
NC score	0.891035 (rank : 22)	θ value	1.31376e-75 (rank : 15)
Query Neighborhood Hits	87	Target Neighborhood Hits	257	Shared Neighborhood Hits	40
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

OXRP_HUMAN
NC score	0.874642 (rank : 23)	θ value	8.28633e-54 (rank : 23)
Query Neighborhood Hits	87	Target Neighborhood Hits	544	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

ANR45_HUMAN
NC score	0.248680 (rank : 24)	θ value	0.000602161 (rank : 24)
Query Neighborhood Hits	87	Target Neighborhood Hits	201	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ANR45_MOUSE
NC score	0.189549 (rank : 25)	θ value	0.163984 (rank : 34)
Query Neighborhood Hits	87	Target Neighborhood Hits	204	Shared Neighborhood Hits	14
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

HS12B_MOUSE
NC score	0.145540 (rank : 26)	θ value	0.00390308 (rank : 25)
Query Neighborhood Hits	87	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CZJ2	Gene names	Hspa12b
Domain Architecture
Description	Heat shock 70 kDa protein 12B.

HS12B_HUMAN
NC score	0.091251 (rank : 27)	θ value	0.0330416 (rank : 26)
Query Neighborhood Hits	87	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	Q96MM6, Q9BR52	Gene names	HSPA12B, C20orf60
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 12B.

SFR12_HUMAN
NC score	0.062288 (rank : 28)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	87	Target Neighborhood Hits	553	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

FA44A_HUMAN
NC score	0.060029 (rank : 29)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	87	Target Neighborhood Hits	280	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

CAF1A_HUMAN
NC score	0.058644 (rank : 30)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	87	Target Neighborhood Hits	750	Shared Neighborhood Hits	42
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

COVA1_HUMAN
NC score	0.054730 (rank : 31)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	87	Target Neighborhood Hits	416	Shared Neighborhood Hits	35
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

SFR12_MOUSE
NC score	0.050455 (rank : 32)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	87	Target Neighborhood Hits	486	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

PCIF1_HUMAN
NC score	0.049903 (rank : 33)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	87	Target Neighborhood Hits	92	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

MYH11_HUMAN
NC score	0.048769 (rank : 34)	θ value	0.0563607 (rank : 29)
Query Neighborhood Hits	87	Target Neighborhood Hits	1806	Shared Neighborhood Hits	65
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

CENPU_HUMAN
NC score	0.046926 (rank : 35)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	87	Target Neighborhood Hits	289	Shared Neighborhood Hits	26
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

DYXC1_HUMAN
NC score	0.046658 (rank : 36)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	87	Target Neighborhood Hits	261	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

MYH10_HUMAN
NC score	0.045221 (rank : 37)	θ value	0.0961366 (rank : 32)
Query Neighborhood Hits	87	Target Neighborhood Hits	1620	Shared Neighborhood Hits	62
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
NC score	0.044730 (rank : 38)	θ value	0.0961366 (rank : 33)
Query Neighborhood Hits	87	Target Neighborhood Hits	1612	Shared Neighborhood Hits	61
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH9_HUMAN
NC score	0.044220 (rank : 39)	θ value	0.0736092 (rank : 30)
Query Neighborhood Hits	87	Target Neighborhood Hits	1762	Shared Neighborhood Hits	65
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
NC score	0.042743 (rank : 40)	θ value	0.0431538 (rank : 27)
Query Neighborhood Hits	87	Target Neighborhood Hits	1829	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH11_MOUSE
NC score	0.041633 (rank : 41)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	87	Target Neighborhood Hits	1777	Shared Neighborhood Hits	60
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

PCIF1_MOUSE
NC score	0.041364 (rank : 42)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	87	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	P59114	Gene names	Pcif1
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

GOGB1_HUMAN
NC score	0.039081 (rank : 43)	θ value	0.0563607 (rank : 28)
Query Neighborhood Hits	87	Target Neighborhood Hits	2297	Shared Neighborhood Hits	64
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

UBXD2_HUMAN
NC score	0.036365 (rank : 44)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	87	Target Neighborhood Hits	241	Shared Neighborhood Hits	20
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

CENPJ_HUMAN
NC score	0.036169 (rank : 45)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	87	Target Neighborhood Hits	721	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

U2AFM_HUMAN
NC score	0.034738 (rank : 46)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	87	Target Neighborhood Hits	577	Shared Neighborhood Hits	33
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

MYH14_MOUSE
NC score	0.033954 (rank : 47)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	87	Target Neighborhood Hits	1225	Shared Neighborhood Hits	56
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

TNNT2_HUMAN
NC score	0.033617 (rank : 48)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	87	Target Neighborhood Hits	433	Shared Neighborhood Hits	32
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

UBXD2_MOUSE
NC score	0.033498 (rank : 49)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	87	Target Neighborhood Hits	183	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VCH8, Q8BW17	Gene names	Ubxd2, Ubxdc1
Domain Architecture
Description	UBX domain-containing protein 2.

MYH7_HUMAN
NC score	0.033078 (rank : 50)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	87	Target Neighborhood Hits	1559	Shared Neighborhood Hits	57
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH6_MOUSE
NC score	0.032380 (rank : 51)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	87	Target Neighborhood Hits	1501	Shared Neighborhood Hits	58
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

CENPF_HUMAN
NC score	0.031530 (rank : 52)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	87	Target Neighborhood Hits	1932	Shared Neighborhood Hits	56
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

MYO6_HUMAN
NC score	0.031410 (rank : 53)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	87	Target Neighborhood Hits	727	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

BPAEA_MOUSE
NC score	0.030313 (rank : 54)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	87	Target Neighborhood Hits	1480	Shared Neighborhood Hits	56
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GOGA4_HUMAN
NC score	0.029766 (rank : 55)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	87	Target Neighborhood Hits	2034	Shared Neighborhood Hits	62
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MYH6_HUMAN
NC score	0.029699 (rank : 56)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	87	Target Neighborhood Hits	1426	Shared Neighborhood Hits	56
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

DYH5_HUMAN
NC score	0.028585 (rank : 57)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	87	Target Neighborhood Hits	323	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

LAMB1_MOUSE
NC score	0.028347 (rank : 58)	θ value	0.0961366 (rank : 31)
Query Neighborhood Hits	87	Target Neighborhood Hits	919	Shared Neighborhood Hits	34
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MYO6_MOUSE
NC score	0.028211 (rank : 59)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	87	Target Neighborhood Hits	586	Shared Neighborhood Hits	33
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

TNNT2_MOUSE
NC score	0.027820 (rank : 60)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	87	Target Neighborhood Hits	395	Shared Neighborhood Hits	29
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

DYH5_MOUSE
NC score	0.027777 (rank : 61)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	87	Target Neighborhood Hits	286	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

FLNA_HUMAN
NC score	0.026892 (rank : 62)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	87	Target Neighborhood Hits	138	Shared Neighborhood Hits	12
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

SMC4_HUMAN
NC score	0.026385 (rank : 63)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	87	Target Neighborhood Hits	937	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

REST_HUMAN
NC score	0.025580 (rank : 64)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	87	Target Neighborhood Hits	1605	Shared Neighborhood Hits	58
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

MYH3_HUMAN
NC score	0.025237 (rank : 65)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	87	Target Neighborhood Hits	1660	Shared Neighborhood Hits	56
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

BRE1B_MOUSE
NC score	0.025035 (rank : 66)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	87	Target Neighborhood Hits	970	Shared Neighborhood Hits	40
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

3BP5_HUMAN
NC score	0.024759 (rank : 67)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	87	Target Neighborhood Hits	375	Shared Neighborhood Hits	29
SwissProt Accessions	O60239	Gene names	SH3BP5, SAB
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

3BP5_MOUSE
NC score	0.024488 (rank : 68)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	87	Target Neighborhood Hits	346	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z131, Q8C903, Q8VCZ0	Gene names	Sh3bp5, Sab
Domain Architecture
Description	SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK).

MY18B_HUMAN
NC score	0.024389 (rank : 69)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	87	Target Neighborhood Hits	1299	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

BRE1B_HUMAN
NC score	0.024317 (rank : 70)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	87	Target Neighborhood Hits	1040	Shared Neighborhood Hits	38
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

FLNA_MOUSE
NC score	0.022346 (rank : 71)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	87	Target Neighborhood Hits	142	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

EEA1_HUMAN
NC score	0.021716 (rank : 72)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	87	Target Neighborhood Hits	1796	Shared Neighborhood Hits	55
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

DZIP3_MOUSE
NC score	0.020556 (rank : 73)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	87	Target Neighborhood Hits	414	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

K2C3_HUMAN
NC score	0.020052 (rank : 74)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	87	Target Neighborhood Hits	443	Shared Neighborhood Hits	39
SwissProt Accessions	P12035, Q701L8	Gene names	KRT3
Domain Architecture
Description	Keratin, type II cytoskeletal 3 (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (65 kDa cytokeratin).

PDP1_HUMAN
NC score	0.019971 (rank : 75)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	87	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P0J1, Q5U5K1	Gene names	PDP1, PDP, PPM2C
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 1, mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C).

PDP1_MOUSE
NC score	0.019893 (rank : 76)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	87	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q3UV70	Gene names	Pdp1, Ppm2c
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 1, mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C).

KNTC2_HUMAN
NC score	0.017728 (rank : 77)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	87	Target Neighborhood Hits	673	Shared Neighborhood Hits	36
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

CLUS_HUMAN
NC score	0.017169 (rank : 78)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	87	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	P10909, P11380, P11381, Q7Z5B9	Gene names	CLU
Domain Architecture
Description	Clusterin precursor (Complement-associated protein SP-40,40) (Complement cytolysis inhibitor) (CLI) (NA1/NA2) (Apolipoprotein J) (Apo-J) (Testosterone-repressed prostate message 2) (TRPM-2) [Contains: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain)].

NDE1_HUMAN
NC score	0.016242 (rank : 79)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	87	Target Neighborhood Hits	823	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

NDE1_MOUSE
NC score	0.015813 (rank : 80)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	87	Target Neighborhood Hits	602	Shared Neighborhood Hits	37
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

CI039_HUMAN
NC score	0.015655 (rank : 81)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	87	Target Neighborhood Hits	1171	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

ANR26_HUMAN
NC score	0.015507 (rank : 82)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	87	Target Neighborhood Hits	1614	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

NUMA1_HUMAN
NC score	0.014718 (rank : 83)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	87	Target Neighborhood Hits	1523	Shared Neighborhood Hits	46
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

K2C1_HUMAN
NC score	0.013632 (rank : 84)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	87	Target Neighborhood Hits	624	Shared Neighborhood Hits	43
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

K2C7_HUMAN
NC score	0.012801 (rank : 85)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	87	Target Neighborhood Hits	369	Shared Neighborhood Hits	34
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

APOL2_HUMAN
NC score	0.009962 (rank : 86)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	87	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQE5, O95915, Q5TH96, Q969T6, Q9BT28, Q9UGT1, Q9UH10	Gene names	APOL2
Domain Architecture
Description	Apolipoprotein-L2 (Apolipoprotein L-II) (ApoL-II).

PWP1_MOUSE
NC score	0.009016 (rank : 87)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	87	Target Neighborhood Hits	278	Shared Neighborhood Hits	4
SwissProt Accessions	Q99LL5, Q9D6T6	Gene names	Pwp1
Domain Architecture	No domain graphic available
Description	Periodic tryptophan protein 1 homolog.

K2C6G_MOUSE
NC score	0.008704 (rank : 88)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	87	Target Neighborhood Hits	452	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R0H5, Q7TPF3, Q9D0X6	Gene names	Krt6g, K6irs1, Krt2-6g
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6G (Cytokeratin-6G) (CK 6G) (K6g keratin) (Keratin-K6irs) (mK6irs1/Krt2-6g).

IF4G3_HUMAN
NC score	0.004278 (rank : 89)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	87	Target Neighborhood Hits	247	Shared Neighborhood Hits	12
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

LRC8E_MOUSE
NC score	0.000533 (rank : 90)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	87	Target Neighborhood Hits	256	Shared Neighborhood Hits	2
SwissProt Accessions	Q66JT1	Gene names	Lrrc8e
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8E.