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Network neighborhood for query Sequence : GNDS_MOUSE

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GNDS_MOUSE
SwissProt Accessions	Q03385	Gene names	Ralgds, Rgds
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GNDS_HUMAN
θ value	0 (rank : 1)	NC score	0.969520 (rank : 2)
Query Neighborhood Hits	115	Target Neighborhood Hits	201	Shared Neighborhood Hits	63
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

GNDS_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	115	Target Neighborhood Hits	115	Shared Neighborhood Hits	115
SwissProt Accessions	Q03385	Gene names	Ralgds, Rgds
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

RGL1_HUMAN
θ value	3.51195e-137 (rank : 3)	NC score	0.946363 (rank : 3)
Query Neighborhood Hits	115	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZL6, Q9HBY3, Q9HBY4, Q9NZL5, Q9UG43, Q9Y2G6	Gene names	RGL1, KIAA0959, RGL
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1).

RGL1_MOUSE
θ value	1.12976e-135 (rank : 4)	NC score	0.945276 (rank : 4)
Query Neighborhood Hits	115	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q60695	Gene names	Rgl1, Rgl
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1).

RGDSR_HUMAN
θ value	4.82422e-78 (rank : 5)	NC score	0.922031 (rank : 5)
Query Neighborhood Hits	115	Target Neighborhood Hits	63	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IZJ4	Gene names	RGR
Domain Architecture
Description	Ral-GDS-related protein (hRGR).

RGL2_HUMAN
θ value	1.89707e-74 (rank : 6)	NC score	0.912978 (rank : 6)
Query Neighborhood Hits	115	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	O15211, Q9Y3F3	Gene names	RGL2, RAB2L
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

RGL2_MOUSE
θ value	9.41505e-74 (rank : 7)	NC score	0.908729 (rank : 7)
Query Neighborhood Hits	115	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q61193, Q9QUJ2	Gene names	Rgl2, Rab2l, Rlf
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

GNRP_HUMAN
θ value	4.43474e-23 (rank : 8)	NC score	0.575476 (rank : 9)
Query Neighborhood Hits	115	Target Neighborhood Hits	239	Shared Neighborhood Hits	24
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
θ value	5.79196e-23 (rank : 9)	NC score	0.561990 (rank : 11)
Query Neighborhood Hits	115	Target Neighborhood Hits	191	Shared Neighborhood Hits	23
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

RPGF1_HUMAN
θ value	5.60996e-18 (rank : 10)	NC score	0.678404 (rank : 8)
Query Neighborhood Hits	115	Target Neighborhood Hits	262	Shared Neighborhood Hits	29
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

SOS2_HUMAN
θ value	1.80466e-16 (rank : 11)	NC score	0.573262 (rank : 10)
Query Neighborhood Hits	115	Target Neighborhood Hits	193	Shared Neighborhood Hits	30
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

SOS1_MOUSE
θ value	3.40345e-15 (rank : 12)	NC score	0.555893 (rank : 12)
Query Neighborhood Hits	115	Target Neighborhood Hits	281	Shared Neighborhood Hits	45
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SOS1_HUMAN
θ value	5.8054e-15 (rank : 13)	NC score	0.550519 (rank : 13)
Query Neighborhood Hits	115	Target Neighborhood Hits	274	Shared Neighborhood Hits	46
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

RPGF6_HUMAN
θ value	5.43371e-13 (rank : 14)	NC score	0.489468 (rank : 16)
Query Neighborhood Hits	115	Target Neighborhood Hits	266	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

RPGF2_HUMAN
θ value	4.59992e-12 (rank : 15)	NC score	0.505197 (rank : 14)
Query Neighborhood Hits	115	Target Neighborhood Hits	242	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

GRP3_HUMAN
θ value	6.64225e-11 (rank : 16)	NC score	0.501866 (rank : 15)
Query Neighborhood Hits	115	Target Neighborhood Hits	131	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

STAT2_MOUSE
θ value	1.06045e-08 (rank : 17)	NC score	0.101772 (rank : 23)
Query Neighborhood Hits	115	Target Neighborhood Hits	175	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

RPGF4_HUMAN
θ value	8.97725e-08 (rank : 18)	NC score	0.438077 (rank : 19)
Query Neighborhood Hits	115	Target Neighborhood Hits	88	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

RPGF5_HUMAN
θ value	1.17247e-07 (rank : 19)	NC score	0.484102 (rank : 17)
Query Neighborhood Hits	115	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q92565, Q8IXU5	Gene names	RAPGEF5, GFR, KIAA0277, MRGEF
Domain Architecture
Description	Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (Related to Epac) (Repac) (M-Ras-regulated Rap GEF) (MR-GEF).

RPGF4_MOUSE
θ value	1.99992e-07 (rank : 20)	NC score	0.433756 (rank : 20)
Query Neighborhood Hits	115	Target Neighborhood Hits	80	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

RPGF5_MOUSE
θ value	1.99992e-07 (rank : 21)	NC score	0.470939 (rank : 18)
Query Neighborhood Hits	115	Target Neighborhood Hits	85	Shared Neighborhood Hits	23
SwissProt Accessions	Q8C0Q9, Q8BJJ9, Q8C0R5	Gene names	Rapgef5, Gfr, Kiaa0277, Mrgef
Domain Architecture
Description	Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF).

RPGF3_MOUSE
θ value	1.29631e-06 (rank : 22)	NC score	0.357338 (rank : 22)
Query Neighborhood Hits	115	Target Neighborhood Hits	54	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VCC8, Q8BZK9, Q8R1R1	Gene names	Rapgef3, Epac, Epac1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1).

SON_HUMAN
θ value	1.87187e-05 (rank : 23)	NC score	0.096430 (rank : 24)
Query Neighborhood Hits	115	Target Neighborhood Hits	1568	Shared Neighborhood Hits	62
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

RPGF3_HUMAN
θ value	9.29e-05 (rank : 24)	NC score	0.394686 (rank : 21)
Query Neighborhood Hits	115	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	O95398, O95634, Q8WVN0	Gene names	RAPGEF3, CGEF1, EPAC, EPAC1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).

NFH_MOUSE
θ value	0.00020696 (rank : 25)	NC score	0.043899 (rank : 56)
Query Neighborhood Hits	115	Target Neighborhood Hits	2247	Shared Neighborhood Hits	57
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SON_MOUSE
θ value	0.00298849 (rank : 26)	NC score	0.093168 (rank : 25)
Query Neighborhood Hits	115	Target Neighborhood Hits	957	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

PO6F1_MOUSE
θ value	0.00869519 (rank : 27)	NC score	0.034728 (rank : 68)
Query Neighborhood Hits	115	Target Neighborhood Hits	581	Shared Neighborhood Hits	23
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

NOTC2_HUMAN
θ value	0.0113563 (rank : 28)	NC score	0.017169 (rank : 91)
Query Neighborhood Hits	115	Target Neighborhood Hits	1113	Shared Neighborhood Hits	21
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	0.0113563 (rank : 29)	NC score	0.015851 (rank : 95)
Query Neighborhood Hits	115	Target Neighborhood Hits	1069	Shared Neighborhood Hits	13
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

GFI1_MOUSE
θ value	0.0252991 (rank : 30)	NC score	0.002105 (rank : 121)
Query Neighborhood Hits	115	Target Neighborhood Hits	736	Shared Neighborhood Hits	5
SwissProt Accessions	P70338, O09063	Gene names	Gfi1, Gfi-1
Domain Architecture	No domain graphic available
Description	Zinc finger protein Gfi-1 (Growth factor independence 1).

MUC1_HUMAN
θ value	0.0252991 (rank : 31)	NC score	0.053209 (rank : 45)
Query Neighborhood Hits	115	Target Neighborhood Hits	975	Shared Neighborhood Hits	43
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

IF4G1_MOUSE
θ value	0.0431538 (rank : 32)	NC score	0.057914 (rank : 36)
Query Neighborhood Hits	115	Target Neighborhood Hits	534	Shared Neighborhood Hits	33
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

RTN4_MOUSE
θ value	0.0563607 (rank : 33)	NC score	0.050580 (rank : 51)
Query Neighborhood Hits	115	Target Neighborhood Hits	341	Shared Neighborhood Hits	32
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

MILK1_MOUSE
θ value	0.0736092 (rank : 34)	NC score	0.050573 (rank : 52)
Query Neighborhood Hits	115	Target Neighborhood Hits	788	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SVIL_MOUSE
θ value	0.0961366 (rank : 35)	NC score	0.033683 (rank : 71)
Query Neighborhood Hits	115	Target Neighborhood Hits	439	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

MDC1_MOUSE
θ value	0.125558 (rank : 36)	NC score	0.064977 (rank : 33)
Query Neighborhood Hits	115	Target Neighborhood Hits	998	Shared Neighborhood Hits	47
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

AFAD_HUMAN
θ value	0.163984 (rank : 37)	NC score	0.049153 (rank : 54)
Query Neighborhood Hits	115	Target Neighborhood Hits	689	Shared Neighborhood Hits	20
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

MDC1_HUMAN
θ value	0.163984 (rank : 38)	NC score	0.073042 (rank : 28)
Query Neighborhood Hits	115	Target Neighborhood Hits	1446	Shared Neighborhood Hits	59
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CK024_HUMAN
θ value	0.21417 (rank : 39)	NC score	0.079125 (rank : 26)
Query Neighborhood Hits	115	Target Neighborhood Hits	408	Shared Neighborhood Hits	37
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

NCOA6_MOUSE
θ value	0.21417 (rank : 40)	NC score	0.053499 (rank : 44)
Query Neighborhood Hits	115	Target Neighborhood Hits	1076	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PTGIS_HUMAN
θ value	0.279714 (rank : 41)	NC score	0.023738 (rank : 82)
Query Neighborhood Hits	115	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q16647, Q9HAX2, Q9HAX3, Q9HAX4	Gene names	PTGIS, CYP8, CYP8A1
Domain Architecture
Description	Prostacyclin synthase (EC 5.3.99.4) (Prostaglandin I2 synthase).

OGFR_HUMAN
θ value	0.365318 (rank : 42)	NC score	0.059950 (rank : 35)
Query Neighborhood Hits	115	Target Neighborhood Hits	1582	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

BIN1_MOUSE
θ value	0.47712 (rank : 43)	NC score	0.037752 (rank : 63)
Query Neighborhood Hits	115	Target Neighborhood Hits	283	Shared Neighborhood Hits	19
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

JIP1_HUMAN
θ value	0.47712 (rank : 44)	NC score	0.032553 (rank : 74)
Query Neighborhood Hits	115	Target Neighborhood Hits	271	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

BCL9_HUMAN
θ value	0.62314 (rank : 45)	NC score	0.057471 (rank : 37)
Query Neighborhood Hits	115	Target Neighborhood Hits	1008	Shared Neighborhood Hits	46
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CNO_HUMAN
θ value	0.62314 (rank : 46)	NC score	0.040479 (rank : 60)
Query Neighborhood Hits	115	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NUP1, Q96G84	Gene names	CNO
Domain Architecture	No domain graphic available
Description	Protein cappuccino homolog.

RGS3_MOUSE
θ value	0.62314 (rank : 47)	NC score	0.051819 (rank : 50)
Query Neighborhood Hits	115	Target Neighborhood Hits	1621	Shared Neighborhood Hits	51
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

FBXW9_HUMAN
θ value	0.813845 (rank : 48)	NC score	0.033601 (rank : 72)
Query Neighborhood Hits	115	Target Neighborhood Hits	184	Shared Neighborhood Hits	6
SwissProt Accessions	Q5XUX1, Q9BT89	Gene names	FBXW9, FBW9
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 9 (F-box and WD-40 domain protein 9).

K0319_HUMAN
θ value	0.813845 (rank : 49)	NC score	0.029885 (rank : 77)
Query Neighborhood Hits	115	Target Neighborhood Hits	154	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

BSN_MOUSE
θ value	1.06291 (rank : 50)	NC score	0.044487 (rank : 55)
Query Neighborhood Hits	115	Target Neighborhood Hits	2057	Shared Neighborhood Hits	60
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CO039_HUMAN
θ value	1.06291 (rank : 51)	NC score	0.065802 (rank : 32)
Query Neighborhood Hits	115	Target Neighborhood Hits	264	Shared Neighborhood Hits	36
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

COG8_MOUSE
θ value	1.06291 (rank : 52)	NC score	0.034051 (rank : 69)
Query Neighborhood Hits	115	Target Neighborhood Hits	147	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

SELPL_MOUSE
θ value	1.06291 (rank : 53)	NC score	0.073933 (rank : 27)
Query Neighborhood Hits	115	Target Neighborhood Hits	588	Shared Neighborhood Hits	39
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

BIN1_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.037042 (rank : 65)
Query Neighborhood Hits	115	Target Neighborhood Hits	335	Shared Neighborhood Hits	13
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

CASC3_MOUSE
θ value	1.38821 (rank : 55)	NC score	0.038499 (rank : 62)
Query Neighborhood Hits	115	Target Neighborhood Hits	333	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

HOMEZ_HUMAN
θ value	1.38821 (rank : 56)	NC score	0.021691 (rank : 83)
Query Neighborhood Hits	115	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IX15, Q6P049, Q86XB6, Q9P2A5	Gene names	HOMEZ, KIAA1443
Domain Architecture
Description	Homeobox and leucine zipper protein Homez (Homeodomain leucine zipper- containing factor).

MAP4_HUMAN
θ value	1.38821 (rank : 57)	NC score	0.055039 (rank : 42)
Query Neighborhood Hits	115	Target Neighborhood Hits	428	Shared Neighborhood Hits	36
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

NACAM_MOUSE
θ value	1.38821 (rank : 58)	NC score	0.069039 (rank : 31)
Query Neighborhood Hits	115	Target Neighborhood Hits	1866	Shared Neighborhood Hits	70
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

BCL9_MOUSE
θ value	1.81305 (rank : 59)	NC score	0.052794 (rank : 47)
Query Neighborhood Hits	115	Target Neighborhood Hits	770	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

ELK4_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.016636 (rank : 93)
Query Neighborhood Hits	115	Target Neighborhood Hits	184	Shared Neighborhood Hits	18
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

FANCC_MOUSE
θ value	2.36792 (rank : 61)	NC score	0.020588 (rank : 85)
Query Neighborhood Hits	115	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P50652	Gene names	Fancc, Fac, Facc
Domain Architecture
Description	Fanconi anemia group C protein homolog (Protein FACC).

JHD3D_HUMAN
θ value	2.36792 (rank : 62)	NC score	0.015418 (rank : 97)
Query Neighborhood Hits	115	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

PCLO_HUMAN
θ value	2.36792 (rank : 63)	NC score	0.041523 (rank : 59)
Query Neighborhood Hits	115	Target Neighborhood Hits	2046	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SEPT9_HUMAN
θ value	2.36792 (rank : 64)	NC score	0.030195 (rank : 76)
Query Neighborhood Hits	115	Target Neighborhood Hits	706	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TLE1_MOUSE
θ value	2.36792 (rank : 65)	NC score	0.010358 (rank : 104)
Query Neighborhood Hits	115	Target Neighborhood Hits	491	Shared Neighborhood Hits	17
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

UBP8_HUMAN
θ value	2.36792 (rank : 66)	NC score	0.010073 (rank : 108)
Query Neighborhood Hits	115	Target Neighborhood Hits	751	Shared Neighborhood Hits	18
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

ADA19_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.006521 (rank : 113)
Query Neighborhood Hits	115	Target Neighborhood Hits	381	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

CP250_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.003588 (rank : 117)
Query Neighborhood Hits	115	Target Neighborhood Hits	1805	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CRSP2_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.029157 (rank : 78)
Query Neighborhood Hits	115	Target Neighborhood Hits	380	Shared Neighborhood Hits	23
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

MAGI1_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.016150 (rank : 94)
Query Neighborhood Hits	115	Target Neighborhood Hits	388	Shared Neighborhood Hits	11
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

PTGIS_MOUSE
θ value	3.0926 (rank : 71)	NC score	0.017071 (rank : 92)
Query Neighborhood Hits	115	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	O35074	Gene names	Ptgis, Cyp8
Domain Architecture
Description	Prostacyclin synthase (EC 5.3.99.4) (Prostaglandin I2 synthase).

V1AR_MOUSE
θ value	3.0926 (rank : 72)	NC score	-0.000571 (rank : 125)
Query Neighborhood Hits	115	Target Neighborhood Hits	897	Shared Neighborhood Hits	2
SwissProt Accessions	Q62463, Q62464, Q9QYH2	Gene names	Avpr1a
Domain Architecture
Description	Vasopressin V1a receptor (V1aR) (Vascular/hepatic-type arginine vasopressin receptor) (Antidiuretic hormone receptor 1a) (AVPR V1a).

ARFG3_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.010116 (rank : 107)
Query Neighborhood Hits	115	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

FA11_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.002410 (rank : 119)
Query Neighborhood Hits	115	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

IRF3_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.010377 (rank : 103)
Query Neighborhood Hits	115	Target Neighborhood Hits	129	Shared Neighborhood Hits	5
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

K1802_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.035556 (rank : 66)
Query Neighborhood Hits	115	Target Neighborhood Hits	1596	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LR37B_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.033968 (rank : 70)
Query Neighborhood Hits	115	Target Neighborhood Hits	392	Shared Neighborhood Hits	23
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

MKL2_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.020346 (rank : 86)
Query Neighborhood Hits	115	Target Neighborhood Hits	274	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

NUAK2_MOUSE
θ value	4.03905 (rank : 79)	NC score	-0.001647 (rank : 126)
Query Neighborhood Hits	115	Target Neighborhood Hits	878	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BZN4, Q80ZW3, Q8CIC0, Q9DBV0	Gene names	Nuak2
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 2 (EC 2.7.11.1).

RRFM_MOUSE
θ value	4.03905 (rank : 80)	NC score	0.017842 (rank : 89)
Query Neighborhood Hits	115	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6S7	Gene names	Mrrf
Domain Architecture	No domain graphic available
Description	Ribosome recycling factor, mitochondrial precursor.

SOX30_HUMAN
θ value	4.03905 (rank : 81)	NC score	0.017316 (rank : 90)
Query Neighborhood Hits	115	Target Neighborhood Hits	305	Shared Neighborhood Hits	16
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

TLE1_HUMAN
θ value	4.03905 (rank : 82)	NC score	0.009454 (rank : 111)
Query Neighborhood Hits	115	Target Neighborhood Hits	485	Shared Neighborhood Hits	17
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

UBP36_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.015533 (rank : 96)
Query Neighborhood Hits	115	Target Neighborhood Hits	232	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

WNK3_HUMAN
θ value	4.03905 (rank : 84)	NC score	-0.000306 (rank : 123)
Query Neighborhood Hits	115	Target Neighborhood Hits	948	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

GDF2_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.009073 (rank : 112)
Query Neighborhood Hits	115	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK05, Q9Y571	Gene names	GDF2, BMP9
Domain Architecture
Description	Growth/differentiation factor 2 precursor (GDF-2) (Bone morphogenetic protein 9) (BMP-9).

IWS1_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.018713 (rank : 88)
Query Neighborhood Hits	115	Target Neighborhood Hits	1241	Shared Neighborhood Hits	35
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NFM_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.011381 (rank : 101)
Query Neighborhood Hits	115	Target Neighborhood Hits	1328	Shared Neighborhood Hits	33
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

RTN4_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.042267 (rank : 57)
Query Neighborhood Hits	115	Target Neighborhood Hits	357	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SRRM2_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.041557 (rank : 58)
Query Neighborhood Hits	115	Target Neighborhood Hits	1470	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TCOF_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.039213 (rank : 61)
Query Neighborhood Hits	115	Target Neighborhood Hits	543	Shared Neighborhood Hits	29
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

ZNF18_MOUSE
θ value	5.27518 (rank : 91)	NC score	-0.001954 (rank : 127)
Query Neighborhood Hits	115	Target Neighborhood Hits	743	Shared Neighborhood Hits	4
SwissProt Accessions	Q810A1, Q9D972	Gene names	Znf18, Zfp535
Domain Architecture	No domain graphic available
Description	Zinc finger protein 18 (Zinc finger protein 535).

AIRE_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.009593 (rank : 110)
Query Neighborhood Hits	115	Target Neighborhood Hits	196	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

ANR25_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.013909 (rank : 98)
Query Neighborhood Hits	115	Target Neighborhood Hits	398	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

BAZ2A_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.025345 (rank : 80)
Query Neighborhood Hits	115	Target Neighborhood Hits	780	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CKAP2_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.011373 (rank : 102)
Query Neighborhood Hits	115	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q3V1H1, Q66LN2, Q8BSF0	Gene names	Ckap2
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2.

CSPG2_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.010235 (rank : 105)
Query Neighborhood Hits	115	Target Neighborhood Hits	681	Shared Neighborhood Hits	17
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CT075_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.004162 (rank : 116)
Query Neighborhood Hits	115	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

DOC2G_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.005040 (rank : 115)
Query Neighborhood Hits	115	Target Neighborhood Hits	125	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

FA47A_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.030716 (rank : 75)
Query Neighborhood Hits	115	Target Neighborhood Hits	451	Shared Neighborhood Hits	27
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

MAP1A_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.024619 (rank : 81)
Query Neighborhood Hits	115	Target Neighborhood Hits	1626	Shared Neighborhood Hits	48
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MINT_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.037184 (rank : 64)
Query Neighborhood Hits	115	Target Neighborhood Hits	1291	Shared Neighborhood Hits	50
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MINT_MOUSE
θ value	6.88961 (rank : 102)	NC score	0.032825 (rank : 73)
Query Neighborhood Hits	115	Target Neighborhood Hits	1514	Shared Neighborhood Hits	47
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYLK_MOUSE
θ value	6.88961 (rank : 103)	NC score	-0.000480 (rank : 124)
Query Neighborhood Hits	115	Target Neighborhood Hits	1489	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NBEA_MOUSE
θ value	6.88961 (rank : 104)	NC score	0.006353 (rank : 114)
Query Neighborhood Hits	115	Target Neighborhood Hits	225	Shared Neighborhood Hits	10
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

UBQL3_HUMAN
θ value	6.88961 (rank : 105)	NC score	0.009885 (rank : 109)
Query Neighborhood Hits	115	Target Neighborhood Hits	141	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

ATF6A_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.010134 (rank : 106)
Query Neighborhood Hits	115	Target Neighborhood Hits	174	Shared Neighborhood Hits	9
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

CSPG5_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.020082 (rank : 87)
Query Neighborhood Hits	115	Target Neighborhood Hits	199	Shared Neighborhood Hits	12
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

FURIN_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.003513 (rank : 118)
Query Neighborhood Hits	115	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

LIPA2_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.001273 (rank : 122)
Query Neighborhood Hits	115	Target Neighborhood Hits	1044	Shared Neighborhood Hits	14
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

NFAC1_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.021547 (rank : 84)
Query Neighborhood Hits	115	Target Neighborhood Hits	312	Shared Neighborhood Hits	27
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

OBSCN_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.002217 (rank : 120)
Query Neighborhood Hits	115	Target Neighborhood Hits	1931	Shared Neighborhood Hits	31
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

RUNX2_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.012740 (rank : 100)
Query Neighborhood Hits	115	Target Neighborhood Hits	103	Shared Neighborhood Hits	10
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

RUNX2_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.013249 (rank : 99)
Query Neighborhood Hits	115	Target Neighborhood Hits	119	Shared Neighborhood Hits	10
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

SPR1B_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.035507 (rank : 67)
Query Neighborhood Hits	115	Target Neighborhood Hits	395	Shared Neighborhood Hits	25
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

TARA_MOUSE
θ value	8.99809 (rank : 115)	NC score	0.026855 (rank : 79)
Query Neighborhood Hits	115	Target Neighborhood Hits	1133	Shared Neighborhood Hits	33
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CB027_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.069143 (rank : 30)
Query Neighborhood Hits	115	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q580R0, O43575, Q52M10, Q86XG2	Gene names	C2orf27
Domain Architecture	No domain graphic available
Description	Protein C2orf27.

CDN1C_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.055478 (rank : 40)
Query Neighborhood Hits	115	Target Neighborhood Hits	168	Shared Neighborhood Hits	37
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CN155_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.055912 (rank : 39)
Query Neighborhood Hits	115	Target Neighborhood Hits	385	Shared Neighborhood Hits	39
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CT152_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.051841 (rank : 48)
Query Neighborhood Hits	115	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

GSCR1_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.055428 (rank : 41)
Query Neighborhood Hits	115	Target Neighborhood Hits	674	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

MUC7_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.056666 (rank : 38)
Query Neighborhood Hits	115	Target Neighborhood Hits	538	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PREX1_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.072150 (rank : 29)
Query Neighborhood Hits	115	Target Neighborhood Hits	177	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

PRG4_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.061064 (rank : 34)
Query Neighborhood Hits	115	Target Neighborhood Hits	764	Shared Neighborhood Hits	54
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.053088 (rank : 46)
Query Neighborhood Hits	115	Target Neighborhood Hits	624	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRR12_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.051820 (rank : 49)
Query Neighborhood Hits	115	Target Neighborhood Hits	460	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SELV_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.053589 (rank : 43)
Query Neighborhood Hits	115	Target Neighborhood Hits	118	Shared Neighborhood Hits	26
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

TAF4_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.050186 (rank : 53)
Query Neighborhood Hits	115	Target Neighborhood Hits	687	Shared Neighborhood Hits	44
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

Hits sorted by NC score

GNDS_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	115	Target Neighborhood Hits	115	Shared Neighborhood Hits	115
SwissProt Accessions	Q03385	Gene names	Ralgds, Rgds
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

GNDS_HUMAN
NC score	0.969520 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	115	Target Neighborhood Hits	201	Shared Neighborhood Hits	63
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

RGL1_HUMAN
NC score	0.946363 (rank : 3)	θ value	3.51195e-137 (rank : 3)
Query Neighborhood Hits	115	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZL6, Q9HBY3, Q9HBY4, Q9NZL5, Q9UG43, Q9Y2G6	Gene names	RGL1, KIAA0959, RGL
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1).

RGL1_MOUSE
NC score	0.945276 (rank : 4)	θ value	1.12976e-135 (rank : 4)
Query Neighborhood Hits	115	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q60695	Gene names	Rgl1, Rgl
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1).

RGDSR_HUMAN
NC score	0.922031 (rank : 5)	θ value	4.82422e-78 (rank : 5)
Query Neighborhood Hits	115	Target Neighborhood Hits	63	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IZJ4	Gene names	RGR
Domain Architecture
Description	Ral-GDS-related protein (hRGR).

RGL2_HUMAN
NC score	0.912978 (rank : 6)	θ value	1.89707e-74 (rank : 6)
Query Neighborhood Hits	115	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	O15211, Q9Y3F3	Gene names	RGL2, RAB2L
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

RGL2_MOUSE
NC score	0.908729 (rank : 7)	θ value	9.41505e-74 (rank : 7)
Query Neighborhood Hits	115	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q61193, Q9QUJ2	Gene names	Rgl2, Rab2l, Rlf
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

RPGF1_HUMAN
NC score	0.678404 (rank : 8)	θ value	5.60996e-18 (rank : 10)
Query Neighborhood Hits	115	Target Neighborhood Hits	262	Shared Neighborhood Hits	29
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

GNRP_HUMAN
NC score	0.575476 (rank : 9)	θ value	4.43474e-23 (rank : 8)
Query Neighborhood Hits	115	Target Neighborhood Hits	239	Shared Neighborhood Hits	24
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

SOS2_HUMAN
NC score	0.573262 (rank : 10)	θ value	1.80466e-16 (rank : 11)
Query Neighborhood Hits	115	Target Neighborhood Hits	193	Shared Neighborhood Hits	30
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

GNRP_MOUSE
NC score	0.561990 (rank : 11)	θ value	5.79196e-23 (rank : 9)
Query Neighborhood Hits	115	Target Neighborhood Hits	191	Shared Neighborhood Hits	23
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

SOS1_MOUSE
NC score	0.555893 (rank : 12)	θ value	3.40345e-15 (rank : 12)
Query Neighborhood Hits	115	Target Neighborhood Hits	281	Shared Neighborhood Hits	45
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SOS1_HUMAN
NC score	0.550519 (rank : 13)	θ value	5.8054e-15 (rank : 13)
Query Neighborhood Hits	115	Target Neighborhood Hits	274	Shared Neighborhood Hits	46
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

RPGF2_HUMAN
NC score	0.505197 (rank : 14)	θ value	4.59992e-12 (rank : 15)
Query Neighborhood Hits	115	Target Neighborhood Hits	242	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

GRP3_HUMAN
NC score	0.501866 (rank : 15)	θ value	6.64225e-11 (rank : 16)
Query Neighborhood Hits	115	Target Neighborhood Hits	131	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

RPGF6_HUMAN
NC score	0.489468 (rank : 16)	θ value	5.43371e-13 (rank : 14)
Query Neighborhood Hits	115	Target Neighborhood Hits	266	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

RPGF5_HUMAN
NC score	0.484102 (rank : 17)	θ value	1.17247e-07 (rank : 19)
Query Neighborhood Hits	115	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q92565, Q8IXU5	Gene names	RAPGEF5, GFR, KIAA0277, MRGEF
Domain Architecture
Description	Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (Related to Epac) (Repac) (M-Ras-regulated Rap GEF) (MR-GEF).

RPGF5_MOUSE
NC score	0.470939 (rank : 18)	θ value	1.99992e-07 (rank : 21)
Query Neighborhood Hits	115	Target Neighborhood Hits	85	Shared Neighborhood Hits	23
SwissProt Accessions	Q8C0Q9, Q8BJJ9, Q8C0R5	Gene names	Rapgef5, Gfr, Kiaa0277, Mrgef
Domain Architecture
Description	Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF).

RPGF4_HUMAN
NC score	0.438077 (rank : 19)	θ value	8.97725e-08 (rank : 18)
Query Neighborhood Hits	115	Target Neighborhood Hits	88	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

RPGF4_MOUSE
NC score	0.433756 (rank : 20)	θ value	1.99992e-07 (rank : 20)
Query Neighborhood Hits	115	Target Neighborhood Hits	80	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

RPGF3_HUMAN
NC score	0.394686 (rank : 21)	θ value	9.29e-05 (rank : 24)
Query Neighborhood Hits	115	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	O95398, O95634, Q8WVN0	Gene names	RAPGEF3, CGEF1, EPAC, EPAC1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP).

RPGF3_MOUSE
NC score	0.357338 (rank : 22)	θ value	1.29631e-06 (rank : 22)
Query Neighborhood Hits	115	Target Neighborhood Hits	54	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VCC8, Q8BZK9, Q8R1R1	Gene names	Rapgef3, Epac, Epac1
Domain Architecture
Description	Rap guanine nucleotide exchange factor 3 (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) (Exchange factor directly activated by cAMP 1) (Epac 1).

STAT2_MOUSE
NC score	0.101772 (rank : 23)	θ value	1.06045e-08 (rank : 17)
Query Neighborhood Hits	115	Target Neighborhood Hits	175	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

SON_HUMAN
NC score	0.096430 (rank : 24)	θ value	1.87187e-05 (rank : 23)
Query Neighborhood Hits	115	Target Neighborhood Hits	1568	Shared Neighborhood Hits	62
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SON_MOUSE
NC score	0.093168 (rank : 25)	θ value	0.00298849 (rank : 26)
Query Neighborhood Hits	115	Target Neighborhood Hits	957	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

CK024_HUMAN
NC score	0.079125 (rank : 26)	θ value	0.21417 (rank : 39)
Query Neighborhood Hits	115	Target Neighborhood Hits	408	Shared Neighborhood Hits	37
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

SELPL_MOUSE
NC score	0.073933 (rank : 27)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	115	Target Neighborhood Hits	588	Shared Neighborhood Hits	39
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

MDC1_HUMAN
NC score	0.073042 (rank : 28)	θ value	0.163984 (rank : 38)
Query Neighborhood Hits	115	Target Neighborhood Hits	1446	Shared Neighborhood Hits	59
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PREX1_HUMAN
NC score	0.072150 (rank : 29)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	115	Target Neighborhood Hits	177	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TCU6, Q5JS95, Q5JS96, Q69YL2, Q7Z2L9, Q9BQH0, Q9BX55, Q9H4Q6, Q9P2D2, Q9UGQ4	Gene names	PREX1, KIAA1415
Domain Architecture
Description	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1 protein).

CB027_HUMAN
NC score	0.069143 (rank : 30)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	115	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q580R0, O43575, Q52M10, Q86XG2	Gene names	C2orf27
Domain Architecture	No domain graphic available
Description	Protein C2orf27.

NACAM_MOUSE
NC score	0.069039 (rank : 31)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	115	Target Neighborhood Hits	1866	Shared Neighborhood Hits	70
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CO039_HUMAN
NC score	0.065802 (rank : 32)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	115	Target Neighborhood Hits	264	Shared Neighborhood Hits	36
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

MDC1_MOUSE
NC score	0.064977 (rank : 33)	θ value	0.125558 (rank : 36)
Query Neighborhood Hits	115	Target Neighborhood Hits	998	Shared Neighborhood Hits	47
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PRG4_HUMAN
NC score	0.061064 (rank : 34)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	115	Target Neighborhood Hits	764	Shared Neighborhood Hits	54
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

OGFR_HUMAN
NC score	0.059950 (rank : 35)	θ value	0.365318 (rank : 42)
Query Neighborhood Hits	115	Target Neighborhood Hits	1582	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

IF4G1_MOUSE
NC score	0.057914 (rank : 36)	θ value	0.0431538 (rank : 32)
Query Neighborhood Hits	115	Target Neighborhood Hits	534	Shared Neighborhood Hits	33
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

BCL9_HUMAN
NC score	0.057471 (rank : 37)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	115	Target Neighborhood Hits	1008	Shared Neighborhood Hits	46
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

MUC7_HUMAN
NC score	0.056666 (rank : 38)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	115	Target Neighborhood Hits	538	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

CN155_HUMAN
NC score	0.055912 (rank : 39)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	115	Target Neighborhood Hits	385	Shared Neighborhood Hits	39
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CDN1C_HUMAN
NC score	0.055478 (rank : 40)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	115	Target Neighborhood Hits	168	Shared Neighborhood Hits	37
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

GSCR1_HUMAN
NC score	0.055428 (rank : 41)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	115	Target Neighborhood Hits	674	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

MAP4_HUMAN
NC score	0.055039 (rank : 42)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	115	Target Neighborhood Hits	428	Shared Neighborhood Hits	36
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SELV_HUMAN
NC score	0.053589 (rank : 43)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	115	Target Neighborhood Hits	118	Shared Neighborhood Hits	26
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

NCOA6_MOUSE
NC score	0.053499 (rank : 44)	θ value	0.21417 (rank : 40)
Query Neighborhood Hits	115	Target Neighborhood Hits	1076	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

MUC1_HUMAN
NC score	0.053209 (rank : 45)	θ value	0.0252991 (rank : 31)
Query Neighborhood Hits	115	Target Neighborhood Hits	975	Shared Neighborhood Hits	43
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PRG4_MOUSE
NC score	0.053088 (rank : 46)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	115	Target Neighborhood Hits	624	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

BCL9_MOUSE
NC score	0.052794 (rank : 47)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	115	Target Neighborhood Hits	770	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CT152_HUMAN
NC score	0.051841 (rank : 48)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	115	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

PRR12_HUMAN
NC score	0.051820 (rank : 49)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	115	Target Neighborhood Hits	460	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

RGS3_MOUSE
NC score	0.051819 (rank : 50)	θ value	0.62314 (rank : 47)
Query Neighborhood Hits	115	Target Neighborhood Hits	1621	Shared Neighborhood Hits	51
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RTN4_MOUSE
NC score	0.050580 (rank : 51)	θ value	0.0563607 (rank : 33)
Query Neighborhood Hits	115	Target Neighborhood Hits	341	Shared Neighborhood Hits	32
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

MILK1_MOUSE
NC score	0.050573 (rank : 52)	θ value	0.0736092 (rank : 34)
Query Neighborhood Hits	115	Target Neighborhood Hits	788	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

TAF4_HUMAN
NC score	0.050186 (rank : 53)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	115	Target Neighborhood Hits	687	Shared Neighborhood Hits	44
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

AFAD_HUMAN
NC score	0.049153 (rank : 54)	θ value	0.163984 (rank : 37)
Query Neighborhood Hits	115	Target Neighborhood Hits	689	Shared Neighborhood Hits	20
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

BSN_MOUSE
NC score	0.044487 (rank : 55)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	115	Target Neighborhood Hits	2057	Shared Neighborhood Hits	60
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NFH_MOUSE
NC score	0.043899 (rank : 56)	θ value	0.00020696 (rank : 25)
Query Neighborhood Hits	115	Target Neighborhood Hits	2247	Shared Neighborhood Hits	57
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RTN4_HUMAN
NC score	0.042267 (rank : 57)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	115	Target Neighborhood Hits	357	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SRRM2_MOUSE
NC score	0.041557 (rank : 58)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	115	Target Neighborhood Hits	1470	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PCLO_HUMAN
NC score	0.041523 (rank : 59)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	115	Target Neighborhood Hits	2046	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CNO_HUMAN
NC score	0.040479 (rank : 60)	θ value	0.62314 (rank : 46)
Query Neighborhood Hits	115	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NUP1, Q96G84	Gene names	CNO
Domain Architecture	No domain graphic available
Description	Protein cappuccino homolog.

TCOF_HUMAN
NC score	0.039213 (rank : 61)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	115	Target Neighborhood Hits	543	Shared Neighborhood Hits	29
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CASC3_MOUSE
NC score	0.038499 (rank : 62)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	115	Target Neighborhood Hits	333	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

BIN1_MOUSE
NC score	0.037752 (rank : 63)	θ value	0.47712 (rank : 43)
Query Neighborhood Hits	115	Target Neighborhood Hits	283	Shared Neighborhood Hits	19
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

MINT_HUMAN
NC score	0.037184 (rank : 64)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	115	Target Neighborhood Hits	1291	Shared Neighborhood Hits	50
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

BIN1_HUMAN
NC score	0.037042 (rank : 65)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	115	Target Neighborhood Hits	335	Shared Neighborhood Hits	13
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

K1802_MOUSE
NC score	0.035556 (rank : 66)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	115	Target Neighborhood Hits	1596	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SPR1B_MOUSE
NC score	0.035507 (rank : 67)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	115	Target Neighborhood Hits	395	Shared Neighborhood Hits	25
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

PO6F1_MOUSE
NC score	0.034728 (rank : 68)	θ value	0.00869519 (rank : 27)
Query Neighborhood Hits	115	Target Neighborhood Hits	581	Shared Neighborhood Hits	23
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

COG8_MOUSE
NC score	0.034051 (rank : 69)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	115	Target Neighborhood Hits	147	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

LR37B_HUMAN
NC score	0.033968 (rank : 70)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	115	Target Neighborhood Hits	392	Shared Neighborhood Hits	23
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

SVIL_MOUSE
NC score	0.033683 (rank : 71)	θ value	0.0961366 (rank : 35)
Query Neighborhood Hits	115	Target Neighborhood Hits	439	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

FBXW9_HUMAN
NC score	0.033601 (rank : 72)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	115	Target Neighborhood Hits	184	Shared Neighborhood Hits	6
SwissProt Accessions	Q5XUX1, Q9BT89	Gene names	FBXW9, FBW9
Domain Architecture	No domain graphic available
Description	F-box/WD repeat protein 9 (F-box and WD-40 domain protein 9).

MINT_MOUSE
NC score	0.032825 (rank : 73)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	115	Target Neighborhood Hits	1514	Shared Neighborhood Hits	47
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

JIP1_HUMAN
NC score	0.032553 (rank : 74)	θ value	0.47712 (rank : 44)
Query Neighborhood Hits	115	Target Neighborhood Hits	271	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

FA47A_HUMAN
NC score	0.030716 (rank : 75)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	115	Target Neighborhood Hits	451	Shared Neighborhood Hits	27
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

SEPT9_HUMAN
NC score	0.030195 (rank : 76)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	115	Target Neighborhood Hits	706	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

K0319_HUMAN
NC score	0.029885 (rank : 77)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	115	Target Neighborhood Hits	154	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

CRSP2_HUMAN
NC score	0.029157 (rank : 78)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	115	Target Neighborhood Hits	380	Shared Neighborhood Hits	23
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

TARA_MOUSE
NC score	0.026855 (rank : 79)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	115	Target Neighborhood Hits	1133	Shared Neighborhood Hits	33
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

BAZ2A_HUMAN
NC score	0.025345 (rank : 80)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	115	Target Neighborhood Hits	780	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

MAP1A_HUMAN
NC score	0.024619 (rank : 81)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	115	Target Neighborhood Hits	1626	Shared Neighborhood Hits	48
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PTGIS_HUMAN
NC score	0.023738 (rank : 82)	θ value	0.279714 (rank : 41)
Query Neighborhood Hits	115	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q16647, Q9HAX2, Q9HAX3, Q9HAX4	Gene names	PTGIS, CYP8, CYP8A1
Domain Architecture
Description	Prostacyclin synthase (EC 5.3.99.4) (Prostaglandin I2 synthase).

HOMEZ_HUMAN
NC score	0.021691 (rank : 83)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	115	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IX15, Q6P049, Q86XB6, Q9P2A5	Gene names	HOMEZ, KIAA1443
Domain Architecture
Description	Homeobox and leucine zipper protein Homez (Homeodomain leucine zipper- containing factor).

NFAC1_HUMAN
NC score	0.021547 (rank : 84)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	115	Target Neighborhood Hits	312	Shared Neighborhood Hits	27
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

FANCC_MOUSE
NC score	0.020588 (rank : 85)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	115	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P50652	Gene names	Fancc, Fac, Facc
Domain Architecture
Description	Fanconi anemia group C protein homolog (Protein FACC).

MKL2_HUMAN
NC score	0.020346 (rank : 86)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	115	Target Neighborhood Hits	274	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

CSPG5_HUMAN
NC score	0.020082 (rank : 87)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	115	Target Neighborhood Hits	199	Shared Neighborhood Hits	12
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

IWS1_HUMAN
NC score	0.018713 (rank : 88)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	115	Target Neighborhood Hits	1241	Shared Neighborhood Hits	35
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RRFM_MOUSE
NC score	0.017842 (rank : 89)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	115	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6S7	Gene names	Mrrf
Domain Architecture	No domain graphic available
Description	Ribosome recycling factor, mitochondrial precursor.

SOX30_HUMAN
NC score	0.017316 (rank : 90)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	115	Target Neighborhood Hits	305	Shared Neighborhood Hits	16
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

NOTC2_HUMAN
NC score	0.017169 (rank : 91)	θ value	0.0113563 (rank : 28)
Query Neighborhood Hits	115	Target Neighborhood Hits	1113	Shared Neighborhood Hits	21
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PTGIS_MOUSE
NC score	0.017071 (rank : 92)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	115	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	O35074	Gene names	Ptgis, Cyp8
Domain Architecture
Description	Prostacyclin synthase (EC 5.3.99.4) (Prostaglandin I2 synthase).

ELK4_HUMAN
NC score	0.016636 (rank : 93)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	115	Target Neighborhood Hits	184	Shared Neighborhood Hits	18
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

MAGI1_HUMAN
NC score	0.016150 (rank : 94)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	115	Target Neighborhood Hits	388	Shared Neighborhood Hits	11
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

NOTC2_MOUSE
NC score	0.015851 (rank : 95)	θ value	0.0113563 (rank : 29)
Query Neighborhood Hits	115	Target Neighborhood Hits	1069	Shared Neighborhood Hits	13
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

UBP36_HUMAN
NC score	0.015533 (rank : 96)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	115	Target Neighborhood Hits	232	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

JHD3D_HUMAN
NC score	0.015418 (rank : 97)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	115	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

ANR25_MOUSE
NC score	0.013909 (rank : 98)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	115	Target Neighborhood Hits	398	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

RUNX2_MOUSE
NC score	0.013249 (rank : 99)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	115	Target Neighborhood Hits	119	Shared Neighborhood Hits	10
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

RUNX2_HUMAN
NC score	0.012740 (rank : 100)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	115	Target Neighborhood Hits	103	Shared Neighborhood Hits	10
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

NFM_HUMAN
NC score	0.011381 (rank : 101)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	115	Target Neighborhood Hits	1328	Shared Neighborhood Hits	33
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

CKAP2_MOUSE
NC score	0.011373 (rank : 102)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	115	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q3V1H1, Q66LN2, Q8BSF0	Gene names	Ckap2
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2.

IRF3_HUMAN
NC score	0.010377 (rank : 103)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	115	Target Neighborhood Hits	129	Shared Neighborhood Hits	5
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

TLE1_MOUSE
NC score	0.010358 (rank : 104)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	115	Target Neighborhood Hits	491	Shared Neighborhood Hits	17
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

CSPG2_HUMAN
NC score	0.010235 (rank : 105)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	115	Target Neighborhood Hits	681	Shared Neighborhood Hits	17
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

ATF6A_HUMAN
NC score	0.010134 (rank : 106)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	115	Target Neighborhood Hits	174	Shared Neighborhood Hits	9
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

ARFG3_HUMAN
NC score	0.010116 (rank : 107)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	115	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

UBP8_HUMAN
NC score	0.010073 (rank : 108)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	115	Target Neighborhood Hits	751	Shared Neighborhood Hits	18
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBQL3_HUMAN
NC score	0.009885 (rank : 109)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	115	Target Neighborhood Hits	141	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

AIRE_MOUSE
NC score	0.009593 (rank : 110)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	115	Target Neighborhood Hits	196	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

TLE1_HUMAN
NC score	0.009454 (rank : 111)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	115	Target Neighborhood Hits	485	Shared Neighborhood Hits	17
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

GDF2_HUMAN
NC score	0.009073 (rank : 112)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	115	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK05, Q9Y571	Gene names	GDF2, BMP9
Domain Architecture
Description	Growth/differentiation factor 2 precursor (GDF-2) (Bone morphogenetic protein 9) (BMP-9).

ADA19_HUMAN
NC score	0.006521 (rank : 113)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	115	Target Neighborhood Hits	381	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

NBEA_MOUSE
NC score	0.006353 (rank : 114)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	115	Target Neighborhood Hits	225	Shared Neighborhood Hits	10
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

DOC2G_MOUSE
NC score	0.005040 (rank : 115)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	115	Target Neighborhood Hits	125	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

CT075_HUMAN
NC score	0.004162 (rank : 116)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	115	Target Neighborhood Hits	387	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

CP250_HUMAN
NC score	0.003588 (rank : 117)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	115	Target Neighborhood Hits	1805	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

FURIN_MOUSE
NC score	0.003513 (rank : 118)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	115	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

FA11_MOUSE
NC score	0.002410 (rank : 119)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	115	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

OBSCN_HUMAN
NC score	0.002217 (rank : 120)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	115	Target Neighborhood Hits	1931	Shared Neighborhood Hits	31
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

GFI1_MOUSE
NC score	0.002105 (rank : 121)	θ value	0.0252991 (rank : 30)
Query Neighborhood Hits	115	Target Neighborhood Hits	736	Shared Neighborhood Hits	5
SwissProt Accessions	P70338, O09063	Gene names	Gfi1, Gfi-1
Domain Architecture	No domain graphic available
Description	Zinc finger protein Gfi-1 (Growth factor independence 1).

LIPA2_HUMAN
NC score	0.001273 (rank : 122)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	115	Target Neighborhood Hits	1044	Shared Neighborhood Hits	14
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

WNK3_HUMAN
NC score	-0.000306 (rank : 123)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	115	Target Neighborhood Hits	948	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYP7, Q9HCK6	Gene names	WNK3, KIAA1566, PRKWNK3
Domain Architecture
Description	Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3).

MYLK_MOUSE
NC score	-0.000480 (rank : 124)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	115	Target Neighborhood Hits	1489	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

V1AR_MOUSE
NC score	-0.000571 (rank : 125)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	115	Target Neighborhood Hits	897	Shared Neighborhood Hits	2
SwissProt Accessions	Q62463, Q62464, Q9QYH2	Gene names	Avpr1a
Domain Architecture
Description	Vasopressin V1a receptor (V1aR) (Vascular/hepatic-type arginine vasopressin receptor) (Antidiuretic hormone receptor 1a) (AVPR V1a).

NUAK2_MOUSE
NC score	-0.001647 (rank : 126)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	115	Target Neighborhood Hits	878	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BZN4, Q80ZW3, Q8CIC0, Q9DBV0	Gene names	Nuak2
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 2 (EC 2.7.11.1).

ZNF18_MOUSE
NC score	-0.001954 (rank : 127)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	115	Target Neighborhood Hits	743	Shared Neighborhood Hits	4
SwissProt Accessions	Q810A1, Q9D972	Gene names	Znf18, Zfp535
Domain Architecture	No domain graphic available
Description	Zinc finger protein 18 (Zinc finger protein 535).