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Network neighborhood for query Sequence : ENT1_HUMAN

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ENT1_HUMAN
SwissProt Accessions	P61550	Gene names
Domain Architecture	No domain graphic available
Description	HERV-T_19q13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-T Env protein) [Includes: Surface protein (SU); Transmembrane protein (TM)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ENT1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P61550	Gene names
Domain Architecture	No domain graphic available
Description	HERV-T_19q13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-T Env protein) [Includes: Surface protein (SU); Transmembrane protein (TM)].

ENV2_MOUSE
θ value	3.03575e-64 (rank : 2)	NC score	0.902970 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

ENW1_HUMAN
θ value	2.77775e-25 (rank : 3)	NC score	0.804418 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UQF0, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3	Gene names	ERVWE1
Domain Architecture
Description	HERV-W_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein gPr73) (HERV-7q Envelope protein) (HERV-W envelope protein) (Syncytin) (Syncytin-1) (Enverin) (Env-W) [Contains: Surface protein (SU) (gp50); Transmembrane protein (TM) (gp24)].

ENH1_HUMAN
θ value	1.6852e-22 (rank : 4)	NC score	0.634997 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	Q9N2K0, O00354, Q96L63, Q9UNM3	Gene names
Domain Architecture
Description	HERV-H_2q24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p62) (Env protein HERV-H19) (HERV- H/env62) (Env protein HERV-Hcl.3) [Contains: Surface protein (SU); Transmembrane protein (TM)].

EFC1_HUMAN
θ value	2.43343e-21 (rank : 5)	NC score	0.743970 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	20	Shared Neighborhood Hits	11
SwissProt Accessions	P60507	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Fc1env) (HERV-Fc1env) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH2_HUMAN
θ value	1.058e-16 (rank : 6)	NC score	0.605763 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q9N2J9	Gene names
Domain Architecture
Description	HERV-H_3q26 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p60) (HERV-H/env60) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH3_HUMAN
θ value	1.16975e-15 (rank : 7)	NC score	0.593441 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q9N2J8	Gene names
Domain Architecture
Description	HERV-H_2q24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p59) (HERV-H/env59) [Contains: Surface protein (SU); Transmembrane protein (TM)].

EFR1_HUMAN
θ value	7.58209e-15 (rank : 8)	NC score	0.696444 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	P60508	Gene names	ERVFRDE1
Domain Architecture
Description	HERV-FRD_6p24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-FRD) (Syncytin-2) [Contains: Surface protein (SU); Transmembrane protein (TM)].

EFC2_HUMAN
θ value	1.02475e-11 (rank : 9)	NC score	0.678299 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	P60608	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)2_7q36.2 provirus ancestral Env polyprotein (Envelope polyprotein) (Fc2deltaenv) [Includes: Surface protein (SU); Truncated transmembrane protein (TM)].

ERB1_HUMAN
θ value	0.000158464 (rank : 10)	NC score	0.469840 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

ENR1_HUMAN
θ value	0.125558 (rank : 11)	NC score	0.309662 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q14264	Gene names	ERV3
Domain Architecture	No domain graphic available
Description	HERV-R_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (ERV3 envelope protein) (ERV-3 envelope protein) (HERV-R envelope protein) (ERV-R envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH4_HUMAN
θ value	0.279714 (rank : 12)	NC score	0.378069 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q96L62	Gene names
Domain Architecture
Description	HERV-H_1q41 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-Hcl.7) [Contains: Surface protein (SU); Transmembrane protein (TM)].

PO2F3_MOUSE
θ value	1.81305 (rank : 13)	NC score	0.012799 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	328	Shared Neighborhood Hits	2
SwissProt Accessions	P31362	Gene names	Pou2f3, Epoc1, Oct11, Otf-11, Otf11
Domain Architecture
Description	POU domain, class 2, transcription factor 3 (Octamer-binding transcription factor 11) (Oct-11) (Epoc-1).

FOXD3_MOUSE
θ value	4.03905 (rank : 14)	NC score	0.007712 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q61060	Gene names	Foxd3, Hfh2
Domain Architecture
Description	Forkhead box protein D3 (HNF3/FH transcription factor genesis) (Hepatocyte nuclear factor 3 forkhead homolog 2) (HFH-2).

MTR1L_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.001666 (rank : 19)
Query Neighborhood Hits	18	Target Neighborhood Hits	1180	Shared Neighborhood Hits	2
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

ERD22_MOUSE
θ value	6.88961 (rank : 16)	NC score	0.017321 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQM2, Q4FK20	Gene names	Kdelr2
Domain Architecture	No domain graphic available
Description	ER lumen protein retaining receptor 2 (KDEL receptor 2) (KDEL endoplasmic reticulum protein retention receptor 2).

PIGQ_MOUSE
θ value	6.88961 (rank : 17)	NC score	0.019231 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QYT7, O35120, O35456, Q99L11	Gene names	Pigq, Gpi1h, Mgpi1
Domain Architecture
Description	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (EC 2.4.1.198) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q) (N-acetylglucosamyl transferase component GPI1) (MGpi1p).

ERD22_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.015901 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P33947, Q96E30	Gene names	KDELR2, ERD2.2
Domain Architecture
Description	ER lumen protein retaining receptor 2 (KDEL receptor 2) (KDEL endoplasmic reticulum protein retention receptor 2) (ERD2-like protein 1) (ELP-1).

ENH5_HUMAN
θ value	θ > 10 (rank : 19)	NC score	0.358242 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	P61549	Gene names
Domain Architecture	No domain graphic available
Description	HERV-H_19p13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein RGH1) (Env protein RTLV-H) [Includes: Surface protein (SU)].

Hits sorted by NC score

ENT1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P61550	Gene names
Domain Architecture	No domain graphic available
Description	HERV-T_19q13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-T Env protein) [Includes: Surface protein (SU); Transmembrane protein (TM)].

ENV2_MOUSE
NC score	0.902970 (rank : 2)	θ value	3.03575e-64 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

ENW1_HUMAN
NC score	0.804418 (rank : 3)	θ value	2.77775e-25 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UQF0, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3	Gene names	ERVWE1
Domain Architecture
Description	HERV-W_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein gPr73) (HERV-7q Envelope protein) (HERV-W envelope protein) (Syncytin) (Syncytin-1) (Enverin) (Env-W) [Contains: Surface protein (SU) (gp50); Transmembrane protein (TM) (gp24)].

EFC1_HUMAN
NC score	0.743970 (rank : 4)	θ value	2.43343e-21 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	20	Shared Neighborhood Hits	11
SwissProt Accessions	P60507	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Fc1env) (HERV-Fc1env) [Contains: Surface protein (SU); Transmembrane protein (TM)].

EFR1_HUMAN
NC score	0.696444 (rank : 5)	θ value	7.58209e-15 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	P60508	Gene names	ERVFRDE1
Domain Architecture
Description	HERV-FRD_6p24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-FRD) (Syncytin-2) [Contains: Surface protein (SU); Transmembrane protein (TM)].

EFC2_HUMAN
NC score	0.678299 (rank : 6)	θ value	1.02475e-11 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	P60608	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)2_7q36.2 provirus ancestral Env polyprotein (Envelope polyprotein) (Fc2deltaenv) [Includes: Surface protein (SU); Truncated transmembrane protein (TM)].

ENH1_HUMAN
NC score	0.634997 (rank : 7)	θ value	1.6852e-22 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	Q9N2K0, O00354, Q96L63, Q9UNM3	Gene names
Domain Architecture
Description	HERV-H_2q24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p62) (Env protein HERV-H19) (HERV- H/env62) (Env protein HERV-Hcl.3) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH2_HUMAN
NC score	0.605763 (rank : 8)	θ value	1.058e-16 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q9N2J9	Gene names
Domain Architecture
Description	HERV-H_3q26 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p60) (HERV-H/env60) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH3_HUMAN
NC score	0.593441 (rank : 9)	θ value	1.16975e-15 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q9N2J8	Gene names
Domain Architecture
Description	HERV-H_2q24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p59) (HERV-H/env59) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ERB1_HUMAN
NC score	0.469840 (rank : 10)	θ value	0.000158464 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

ENH4_HUMAN
NC score	0.378069 (rank : 11)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q96L62	Gene names
Domain Architecture
Description	HERV-H_1q41 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-Hcl.7) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH5_HUMAN
NC score	0.358242 (rank : 12)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	P61549	Gene names
Domain Architecture	No domain graphic available
Description	HERV-H_19p13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein RGH1) (Env protein RTLV-H) [Includes: Surface protein (SU)].

ENR1_HUMAN
NC score	0.309662 (rank : 13)	θ value	0.125558 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q14264	Gene names	ERV3
Domain Architecture	No domain graphic available
Description	HERV-R_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (ERV3 envelope protein) (ERV-3 envelope protein) (HERV-R envelope protein) (ERV-R envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

PIGQ_MOUSE
NC score	0.019231 (rank : 14)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QYT7, O35120, O35456, Q99L11	Gene names	Pigq, Gpi1h, Mgpi1
Domain Architecture
Description	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (EC 2.4.1.198) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q) (N-acetylglucosamyl transferase component GPI1) (MGpi1p).

ERD22_MOUSE
NC score	0.017321 (rank : 15)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQM2, Q4FK20	Gene names	Kdelr2
Domain Architecture	No domain graphic available
Description	ER lumen protein retaining receptor 2 (KDEL receptor 2) (KDEL endoplasmic reticulum protein retention receptor 2).

ERD22_HUMAN
NC score	0.015901 (rank : 16)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P33947, Q96E30	Gene names	KDELR2, ERD2.2
Domain Architecture
Description	ER lumen protein retaining receptor 2 (KDEL receptor 2) (KDEL endoplasmic reticulum protein retention receptor 2) (ERD2-like protein 1) (ELP-1).

PO2F3_MOUSE
NC score	0.012799 (rank : 17)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	328	Shared Neighborhood Hits	2
SwissProt Accessions	P31362	Gene names	Pou2f3, Epoc1, Oct11, Otf-11, Otf11
Domain Architecture
Description	POU domain, class 2, transcription factor 3 (Octamer-binding transcription factor 11) (Oct-11) (Epoc-1).

FOXD3_MOUSE
NC score	0.007712 (rank : 18)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q61060	Gene names	Foxd3, Hfh2
Domain Architecture
Description	Forkhead box protein D3 (HNF3/FH transcription factor genesis) (Hepatocyte nuclear factor 3 forkhead homolog 2) (HFH-2).

MTR1L_HUMAN
NC score	0.001666 (rank : 19)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	1180	Shared Neighborhood Hits	2
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).