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Network neighborhood for query Sequence : ENH5_HUMAN

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ENH5_HUMAN
SwissProt Accessions	P61549	Gene names
Domain Architecture	No domain graphic available
Description	HERV-H_19p13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein RGH1) (Env protein RTLV-H) [Includes: Surface protein (SU)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ENH1_HUMAN
θ value	3.0341e-181 (rank : 1)	NC score	0.924569 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q9N2K0, O00354, Q96L63, Q9UNM3	Gene names
Domain Architecture
Description	HERV-H_2q24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p62) (Env protein HERV-H19) (HERV- H/env62) (Env protein HERV-Hcl.3) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH5_HUMAN
θ value	4.1007e-178 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P61549	Gene names
Domain Architecture	No domain graphic available
Description	HERV-H_19p13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein RGH1) (Env protein RTLV-H) [Includes: Surface protein (SU)].

ENH2_HUMAN
θ value	1.78289e-173 (rank : 3)	NC score	0.940041 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	Q9N2J9	Gene names
Domain Architecture
Description	HERV-H_3q26 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p60) (HERV-H/env60) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH4_HUMAN
θ value	6.77497e-173 (rank : 4)	NC score	0.997910 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q96L62	Gene names
Domain Architecture
Description	HERV-H_1q41 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-Hcl.7) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH3_HUMAN
θ value	7.76955e-161 (rank : 5)	NC score	0.950895 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9N2J8	Gene names
Domain Architecture
Description	HERV-H_2q24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p59) (HERV-H/env59) [Contains: Surface protein (SU); Transmembrane protein (TM)].

EFR1_HUMAN
θ value	1.37858e-24 (rank : 6)	NC score	0.782733 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P60508	Gene names	ERVFRDE1
Domain Architecture
Description	HERV-FRD_6p24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-FRD) (Syncytin-2) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENW1_HUMAN
θ value	0.00665767 (rank : 7)	NC score	0.518741 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UQF0, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3	Gene names	ERVWE1
Domain Architecture
Description	HERV-W_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein gPr73) (HERV-7q Envelope protein) (HERV-W envelope protein) (Syncytin) (Syncytin-1) (Enverin) (Env-W) [Contains: Surface protein (SU) (gp50); Transmembrane protein (TM) (gp24)].

ENR1_HUMAN
θ value	0.0961366 (rank : 8)	NC score	0.265027 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q14264	Gene names	ERV3
Domain Architecture	No domain graphic available
Description	HERV-R_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (ERV3 envelope protein) (ERV-3 envelope protein) (HERV-R envelope protein) (ERV-R envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

LPP_HUMAN
θ value	1.06291 (rank : 9)	NC score	0.020254 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	775	Shared Neighborhood Hits	6
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

O56B4_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.004981 (rank : 17)
Query Neighborhood Hits	14	Target Neighborhood Hits	605	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NH76	Gene names	OR56B4
Domain Architecture
Description	Olfactory receptor 56B4.

PO121_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.041238 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	344	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

DLL3_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.001705 (rank : 18)
Query Neighborhood Hits	14	Target Neighborhood Hits	419	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

M3K4_MOUSE
θ value	8.99809 (rank : 13)	NC score	-0.000765 (rank : 19)
Query Neighborhood Hits	14	Target Neighborhood Hits	924	Shared Neighborhood Hits	2
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

TAU_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.005776 (rank : 16)
Query Neighborhood Hits	14	Target Neighborhood Hits	448	Shared Neighborhood Hits	2
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

EFC1_HUMAN
θ value	θ > 10 (rank : 15)	NC score	0.321181 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	P60507	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Fc1env) (HERV-Fc1env) [Contains: Surface protein (SU); Transmembrane protein (TM)].

EFC2_HUMAN
θ value	θ > 10 (rank : 16)	NC score	0.320244 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	P60608	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)2_7q36.2 provirus ancestral Env polyprotein (Envelope polyprotein) (Fc2deltaenv) [Includes: Surface protein (SU); Truncated transmembrane protein (TM)].

ENT1_HUMAN
θ value	θ > 10 (rank : 17)	NC score	0.358242 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	P61550	Gene names
Domain Architecture	No domain graphic available
Description	HERV-T_19q13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-T Env protein) [Includes: Surface protein (SU); Transmembrane protein (TM)].

ENV2_MOUSE
θ value	θ > 10 (rank : 18)	NC score	0.329250 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

ERB1_HUMAN
θ value	θ > 10 (rank : 19)	NC score	0.276355 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

Hits sorted by NC score

ENH5_HUMAN
NC score	0.999962 (rank : 1)	θ value	4.1007e-178 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P61549	Gene names
Domain Architecture	No domain graphic available
Description	HERV-H_19p13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein RGH1) (Env protein RTLV-H) [Includes: Surface protein (SU)].

ENH4_HUMAN
NC score	0.997910 (rank : 2)	θ value	6.77497e-173 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q96L62	Gene names
Domain Architecture
Description	HERV-H_1q41 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-Hcl.7) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH3_HUMAN
NC score	0.950895 (rank : 3)	θ value	7.76955e-161 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9N2J8	Gene names
Domain Architecture
Description	HERV-H_2q24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p59) (HERV-H/env59) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH2_HUMAN
NC score	0.940041 (rank : 4)	θ value	1.78289e-173 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	Q9N2J9	Gene names
Domain Architecture
Description	HERV-H_3q26 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p60) (HERV-H/env60) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENH1_HUMAN
NC score	0.924569 (rank : 5)	θ value	3.0341e-181 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	Q9N2K0, O00354, Q96L63, Q9UNM3	Gene names
Domain Architecture
Description	HERV-H_2q24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Env protein HERV-H/p62) (Env protein HERV-H19) (HERV- H/env62) (Env protein HERV-Hcl.3) [Contains: Surface protein (SU); Transmembrane protein (TM)].

EFR1_HUMAN
NC score	0.782733 (rank : 6)	θ value	1.37858e-24 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P60508	Gene names	ERVFRDE1
Domain Architecture
Description	HERV-FRD_6p24.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-FRD) (Syncytin-2) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENW1_HUMAN
NC score	0.518741 (rank : 7)	θ value	0.00665767 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	22	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UQF0, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3	Gene names	ERVWE1
Domain Architecture
Description	HERV-W_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein gPr73) (HERV-7q Envelope protein) (HERV-W envelope protein) (Syncytin) (Syncytin-1) (Enverin) (Env-W) [Contains: Surface protein (SU) (gp50); Transmembrane protein (TM) (gp24)].

ENT1_HUMAN
NC score	0.358242 (rank : 8)	θ value	θ > 10 (rank : 17)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	7
SwissProt Accessions	P61550	Gene names
Domain Architecture	No domain graphic available
Description	HERV-T_19q13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-T Env protein) [Includes: Surface protein (SU); Transmembrane protein (TM)].

ENV2_MOUSE
NC score	0.329250 (rank : 9)	θ value	θ > 10 (rank : 18)
Query Neighborhood Hits	14	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	P11370, Q61529	Gene names	Fv4, Env
Domain Architecture
Description	Retrovirus-related Env polyprotein from Fv-4 locus.

EFC1_HUMAN
NC score	0.321181 (rank : 10)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	P60507	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)1_Xq21.33 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (Fc1env) (HERV-Fc1env) [Contains: Surface protein (SU); Transmembrane protein (TM)].

EFC2_HUMAN
NC score	0.320244 (rank : 11)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	P60608	Gene names
Domain Architecture	No domain graphic available
Description	HERV-F(c)2_7q36.2 provirus ancestral Env polyprotein (Envelope polyprotein) (Fc2deltaenv) [Includes: Surface protein (SU); Truncated transmembrane protein (TM)].

ERB1_HUMAN
NC score	0.276355 (rank : 12)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	14	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

ENR1_HUMAN
NC score	0.265027 (rank : 13)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q14264	Gene names	ERV3
Domain Architecture	No domain graphic available
Description	HERV-R_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (ERV3 envelope protein) (ERV-3 envelope protein) (HERV-R envelope protein) (ERV-R envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

PO121_HUMAN
NC score	0.041238 (rank : 14)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	344	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

LPP_HUMAN
NC score	0.020254 (rank : 15)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	775	Shared Neighborhood Hits	6
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

TAU_HUMAN
NC score	0.005776 (rank : 16)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	448	Shared Neighborhood Hits	2
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

O56B4_HUMAN
NC score	0.004981 (rank : 17)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	605	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NH76	Gene names	OR56B4
Domain Architecture
Description	Olfactory receptor 56B4.

DLL3_HUMAN
NC score	0.001705 (rank : 18)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	419	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

M3K4_MOUSE
NC score	-0.000765 (rank : 19)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	924	Shared Neighborhood Hits	2
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).