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Network neighborhood for query Sequence : ECEL1_HUMAN

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ECEL1_HUMAN
 
SwissProt Accessions O95672, Q45UD9, Q53RF9, Q6UW86, Q86TH4, Q9NY95 Gene names ECEL1, XCE
Domain
Architecture
Description Endothelin-converting enzyme-like 1 (EC 3.4.24.-) (Xce protein).
Rank Plots



Hits sorted by θ


ECEL1_HUMAN
 
θ value 0 (rank : 1) NC score 0.999962 (rank : 1)
Query Neighborhood Hits 24 Target Neighborhood Hits 24 Shared Neighborhood Hits 24
SwissProt Accessions O95672, Q45UD9, Q53RF9, Q6UW86, Q86TH4, Q9NY95 Gene names ECEL1, XCE
Domain
Architecture
Description Endothelin-converting enzyme-like 1 (EC 3.4.24.-) (Xce protein).
ECEL1_MOUSE
 
θ value 0 (rank : 2) NC score 0.999131 (rank : 2)
Query Neighborhood Hits 24 Target Neighborhood Hits 26 Shared Neighborhood Hits 16
SwissProt Accessions Q9JMI0 Gene names Ecel1, Dine, Xce
Domain
Architecture
Description Endothelin-converting enzyme-like 1 (EC 3.4.24.-) (Xce protein) (Damage-induced neuronal endopeptidase).
ECE1_HUMAN
 
θ value 3.99958e-149 (rank : 3) NC score 0.978238 (rank : 4)
Query Neighborhood Hits 24 Target Neighborhood Hits 27 Shared Neighborhood Hits 12
SwissProt Accessions P42892, Q14217, Q58GE7, Q5THM5, Q5THM7, Q5THM8, Q9UJQ6, Q9UPF4, Q9UPM4, Q9Y501 Gene names ECE1
Domain
Architecture
Description Endothelin-converting enzyme 1 (EC 3.4.24.71) (ECE-1).
ECE1_MOUSE
 
θ value 9.85132e-148 (rank : 4) NC score 0.978396 (rank : 3)
Query Neighborhood Hits 24 Target Neighborhood Hits 23 Shared Neighborhood Hits 12
SwissProt Accessions Q4PZA2, Q4PZ99, Q4PZA1, Q6P9Q9 Gene names Ece1
Domain
Architecture

No domain graphic available

Description Endothelin-converting enzyme 1 (EC 3.4.24.71) (ECE-1).
ECE2_HUMAN
 
θ value 3.7435e-147 (rank : 5) NC score 0.977856 (rank : 5)
Query Neighborhood Hits 24 Target Neighborhood Hits 18 Shared Neighborhood Hits 12
SwissProt Accessions O60344, Q96NX3, Q96NX4 Gene names ECE2, KIAA0604
Domain
Architecture
Description Endothelin-converting enzyme 2 (EC 3.4.24.71) (ECE-2).
MMEL1_MOUSE
 
θ value 1.02182e-136 (rank : 6) NC score 0.972502 (rank : 7)
Query Neighborhood Hits 24 Target Neighborhood Hits 48 Shared Neighborhood Hits 12
SwissProt Accessions Q9JLI3, Q3U495, Q9ERK2, Q9ERK3, Q9QZV6, Q9QZV7 Gene names Mmel1, Nep2, Nl1, Sep
Domain
Architecture

No domain graphic available

Description Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Neprilysin-2) (Neprilysin II) (NL2) (NEPII) (NEP2(m)) (Neprilysin-like peptidase) (NEPLP) (Neprilysin-like 1) (NL-1) (Soluble secreted endopeptidase) [Contains: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))].
MMEL1_HUMAN
 
θ value 1.24909e-134 (rank : 7) NC score 0.972813 (rank : 6)
Query Neighborhood Hits 24 Target Neighborhood Hits 35 Shared Neighborhood Hits 12
SwissProt Accessions Q495T6, Q495T7, Q495T8, Q5SZS6, Q96PH9 Gene names MMEL1, MELL1, MMEL2, NEP2
Domain
Architecture

No domain graphic available

Description Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2) (Neprilysin-2) (Neprilysin II) (NL2) (NEPII) (NEP2(m)) [Contains: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))].
NEP_HUMAN
 
θ value 4.31301e-119 (rank : 8) NC score 0.969570 (rank : 8)
Query Neighborhood Hits 24 Target Neighborhood Hits 25 Shared Neighborhood Hits 12
SwissProt Accessions P08473 Gene names MME, EPN
Domain
Architecture
Description Neprilysin (EC 3.4.24.11) (Neutral endopeptidase) (NEP) (Enkephalinase) (Neutral endopeptidase 24.11) (Atriopeptidase) (Common acute lymphocytic leukemia antigen) (CALLA) (CD10 antigen).
NEP_MOUSE
 
θ value 5.27232e-117 (rank : 9) NC score 0.969299 (rank : 9)
Query Neighborhood Hits 24 Target Neighborhood Hits 27 Shared Neighborhood Hits 12
SwissProt Accessions Q61391, Q6NXX5, Q8K251 Gene names Mme
Domain
Architecture
Description Neprilysin (EC 3.4.24.11) (Neutral endopeptidase) (NEP) (Enkephalinase) (Neutral endopeptidase 24.11) (Atriopeptidase) (CD10 antigen).
PHEX_MOUSE
 
θ value 3.91911e-104 (rank : 10) NC score 0.963634 (rank : 10)
Query Neighborhood Hits 24 Target Neighborhood Hits 14 Shared Neighborhood Hits 12
SwissProt Accessions P70669, P97439 Gene names Phex, Hyp, Pex
Domain
Architecture
Description Metalloendopeptidase homolog PEX (EC 3.4.24.-) (Phosphate regulating neutral endopeptidase) (X-linked hypophosphatemia protein) (HYP) (Vitamin D-resistant hypophosphatemic rickets protein).
PHEX_HUMAN
 
θ value 9.98939e-100 (rank : 11) NC score 0.963305 (rank : 11)
Query Neighborhood Hits 24 Target Neighborhood Hits 17 Shared Neighborhood Hits 12
SwissProt Accessions P78562, O00678, Q13646, Q93032, Q99827 Gene names PHEX, PEX
Domain
Architecture
Description Phosphate-regulating neutral endopeptidase (EC 3.4.24.-) (Metalloendopeptidase homolog PEX) (X-linked hypophosphatemia protein) (HYP) (Vitamin D-resistant hypophosphatemic rickets protein).
KELL_HUMAN
 
θ value 1.45253e-74 (rank : 12) NC score 0.955766 (rank : 12)
Query Neighborhood Hits 24 Target Neighborhood Hits 18 Shared Neighborhood Hits 12
SwissProt Accessions P23276, Q96RS8, Q99885 Gene names KEL
Domain
Architecture
Description Kell blood group glycoprotein (EC 3.4.24.-) (CD238 antigen).
SPTB2_HUMAN
 
θ value 0.813845 (rank : 13) NC score 0.008382 (rank : 16)
Query Neighborhood Hits 24 Target Neighborhood Hits 748 Shared Neighborhood Hits 4
SwissProt Accessions Q01082, O60837, Q16057 Gene names SPTBN1, SPTB2
Domain
Architecture
Description Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).
SPTB2_MOUSE
 
θ value 0.813845 (rank : 14) NC score 0.008310 (rank : 17)
Query Neighborhood Hits 24 Target Neighborhood Hits 770 Shared Neighborhood Hits 4
SwissProt Accessions Q62261, Q5SQL8 Gene names Sptbn1, Spnb-2, Spnb2, Sptb2
Domain
Architecture
Description Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).
ZN192_HUMAN
 
θ value 1.38821 (rank : 15) NC score -0.001303 (rank : 24)
Query Neighborhood Hits 24 Target Neighborhood Hits 789 Shared Neighborhood Hits 2
SwissProt Accessions Q15776, Q4VAR1, Q4VAR2, Q4VAR3, Q9H4T1 Gene names ZNF192
Domain
Architecture
Description Zinc finger protein 192 (LD5-1).
LAMB2_MOUSE
 
θ value 2.36792 (rank : 16) NC score 0.003466 (rank : 21)
Query Neighborhood Hits 24 Target Neighborhood Hits 722 Shared Neighborhood Hits 5
SwissProt Accessions Q61292, Q62182 Gene names Lamb2, Lams
Domain
Architecture
Description Laminin beta-2 chain precursor (S-laminin) (S-LAM).
PSA_HUMAN
 
θ value 4.03905 (rank : 17) NC score 0.014448 (rank : 14)
Query Neighborhood Hits 24 Target Neighborhood Hits 31 Shared Neighborhood Hits 5
SwissProt Accessions P55786, Q6P145, Q9NP16, Q9UEM2 Gene names NPEPPS, PSA
Domain
Architecture
Description Puromycin-sensitive aminopeptidase (EC 3.4.11.-) (PSA).
PSA_MOUSE
 
θ value 4.03905 (rank : 18) NC score 0.014469 (rank : 13)
Query Neighborhood Hits 24 Target Neighborhood Hits 32 Shared Neighborhood Hits 5
SwissProt Accessions Q11011, Q91VJ8 Gene names Npepps, Psa
Domain
Architecture
Description Puromycin-sensitive aminopeptidase (EC 3.4.11.-) (PSA).
SDK1_MOUSE
 
θ value 6.88961 (rank : 19) NC score 0.000591 (rank : 23)
Query Neighborhood Hits 24 Target Neighborhood Hits 495 Shared Neighborhood Hits 2
SwissProt Accessions Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1 Gene names Sdk1
Domain
Architecture

No domain graphic available

Description Protein sidekick-1 precursor.
2DOB_HUMAN
 
θ value 8.99809 (rank : 20) NC score 0.000987 (rank : 22)
Query Neighborhood Hits 24 Target Neighborhood Hits 201 Shared Neighborhood Hits 2
SwissProt Accessions P13765, Q29746, Q29825 Gene names HLA-DOB
Domain
Architecture
Description HLA class II histocompatibility antigen, DO beta chain precursor (MHC class II antigen DOB).
AMPE_HUMAN
 
θ value 8.99809 (rank : 21) NC score 0.009876 (rank : 15)
Query Neighborhood Hits 24 Target Neighborhood Hits 46 Shared Neighborhood Hits 5
SwissProt Accessions Q07075 Gene names ENPEP
Domain
Architecture
Description Glutamyl aminopeptidase (EC 3.4.11.7) (EAP) (Aminopeptidase A) (APA) (Differentiation antigen gp160) (CD249 antigen).
ITIH2_MOUSE
 
θ value 8.99809 (rank : 22) NC score 0.006885 (rank : 19)
Query Neighborhood Hits 24 Target Neighborhood Hits 27 Shared Neighborhood Hits 3
SwissProt Accessions Q61703 Gene names Itih2
Domain
Architecture
Description Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2).
MKS3_MOUSE
 
θ value 8.99809 (rank : 23) NC score 0.007088 (rank : 18)
Query Neighborhood Hits 24 Target Neighborhood Hits 89 Shared Neighborhood Hits 3
SwissProt Accessions Q8BR76, Q78U07 Gene names Tmem67, Mks3
Domain
Architecture

No domain graphic available

Description Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).
UBP40_HUMAN
 
θ value 8.99809 (rank : 24) NC score 0.004395 (rank : 20)
Query Neighborhood Hits 24 Target Neighborhood Hits 81 Shared Neighborhood Hits 2
SwissProt Accessions Q9NVE5, Q6NX38, Q70EL0 Gene names USP40
Domain
Architecture

No domain graphic available

Description Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

Hits sorted by NC score


ECEL1_HUMAN
 
NC score 0.999962 (rank : 1) θ value 0 (rank : 1)
Query Neighborhood Hits 24 Target Neighborhood Hits 24 Shared Neighborhood Hits 24
SwissProt Accessions O95672, Q45UD9, Q53RF9, Q6UW86, Q86TH4, Q9NY95 Gene names ECEL1, XCE
Domain
Architecture
Description Endothelin-converting enzyme-like 1 (EC 3.4.24.-) (Xce protein).
ECEL1_MOUSE
 
NC score 0.999131 (rank : 2) θ value 0 (rank : 2)
Query Neighborhood Hits 24 Target Neighborhood Hits 26 Shared Neighborhood Hits 16
SwissProt Accessions Q9JMI0 Gene names Ecel1, Dine, Xce
Domain
Architecture
Description Endothelin-converting enzyme-like 1 (EC 3.4.24.-) (Xce protein) (Damage-induced neuronal endopeptidase).
ECE1_MOUSE
 
NC score 0.978396 (rank : 3) θ value 9.85132e-148 (rank : 4)
Query Neighborhood Hits 24 Target Neighborhood Hits 23 Shared Neighborhood Hits 12
SwissProt Accessions Q4PZA2, Q4PZ99, Q4PZA1, Q6P9Q9 Gene names Ece1
Domain
Architecture

No domain graphic available

Description Endothelin-converting enzyme 1 (EC 3.4.24.71) (ECE-1).
ECE1_HUMAN
 
NC score 0.978238 (rank : 4) θ value 3.99958e-149 (rank : 3)
Query Neighborhood Hits 24 Target Neighborhood Hits 27 Shared Neighborhood Hits 12
SwissProt Accessions P42892, Q14217, Q58GE7, Q5THM5, Q5THM7, Q5THM8, Q9UJQ6, Q9UPF4, Q9UPM4, Q9Y501 Gene names ECE1
Domain
Architecture
Description Endothelin-converting enzyme 1 (EC 3.4.24.71) (ECE-1).
ECE2_HUMAN
 
NC score 0.977856 (rank : 5) θ value 3.7435e-147 (rank : 5)
Query Neighborhood Hits 24 Target Neighborhood Hits 18 Shared Neighborhood Hits 12
SwissProt Accessions O60344, Q96NX3, Q96NX4 Gene names ECE2, KIAA0604
Domain
Architecture
Description Endothelin-converting enzyme 2 (EC 3.4.24.71) (ECE-2).
MMEL1_HUMAN
 
NC score 0.972813 (rank : 6) θ value 1.24909e-134 (rank : 7)
Query Neighborhood Hits 24 Target Neighborhood Hits 35 Shared Neighborhood Hits 12
SwissProt Accessions Q495T6, Q495T7, Q495T8, Q5SZS6, Q96PH9 Gene names MMEL1, MELL1, MMEL2, NEP2
Domain
Architecture

No domain graphic available

Description Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2) (Neprilysin-2) (Neprilysin II) (NL2) (NEPII) (NEP2(m)) [Contains: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))].
MMEL1_MOUSE
 
NC score 0.972502 (rank : 7) θ value 1.02182e-136 (rank : 6)
Query Neighborhood Hits 24 Target Neighborhood Hits 48 Shared Neighborhood Hits 12
SwissProt Accessions Q9JLI3, Q3U495, Q9ERK2, Q9ERK3, Q9QZV6, Q9QZV7 Gene names Mmel1, Nep2, Nl1, Sep
Domain
Architecture

No domain graphic available

Description Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Neprilysin-2) (Neprilysin II) (NL2) (NEPII) (NEP2(m)) (Neprilysin-like peptidase) (NEPLP) (Neprilysin-like 1) (NL-1) (Soluble secreted endopeptidase) [Contains: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))].
NEP_HUMAN
 
NC score 0.969570 (rank : 8) θ value 4.31301e-119 (rank : 8)
Query Neighborhood Hits 24 Target Neighborhood Hits 25 Shared Neighborhood Hits 12
SwissProt Accessions P08473 Gene names MME, EPN
Domain
Architecture
Description Neprilysin (EC 3.4.24.11) (Neutral endopeptidase) (NEP) (Enkephalinase) (Neutral endopeptidase 24.11) (Atriopeptidase) (Common acute lymphocytic leukemia antigen) (CALLA) (CD10 antigen).
NEP_MOUSE
 
NC score 0.969299 (rank : 9) θ value 5.27232e-117 (rank : 9)
Query Neighborhood Hits 24 Target Neighborhood Hits 27 Shared Neighborhood Hits 12
SwissProt Accessions Q61391, Q6NXX5, Q8K251 Gene names Mme
Domain
Architecture
Description Neprilysin (EC 3.4.24.11) (Neutral endopeptidase) (NEP) (Enkephalinase) (Neutral endopeptidase 24.11) (Atriopeptidase) (CD10 antigen).
PHEX_MOUSE
 
NC score 0.963634 (rank : 10) θ value 3.91911e-104 (rank : 10)
Query Neighborhood Hits 24 Target Neighborhood Hits 14 Shared Neighborhood Hits 12
SwissProt Accessions P70669, P97439 Gene names Phex, Hyp, Pex
Domain
Architecture
Description Metalloendopeptidase homolog PEX (EC 3.4.24.-) (Phosphate regulating neutral endopeptidase) (X-linked hypophosphatemia protein) (HYP) (Vitamin D-resistant hypophosphatemic rickets protein).
PHEX_HUMAN
 
NC score 0.963305 (rank : 11) θ value 9.98939e-100 (rank : 11)
Query Neighborhood Hits 24 Target Neighborhood Hits 17 Shared Neighborhood Hits 12
SwissProt Accessions P78562, O00678, Q13646, Q93032, Q99827 Gene names PHEX, PEX
Domain
Architecture
Description Phosphate-regulating neutral endopeptidase (EC 3.4.24.-) (Metalloendopeptidase homolog PEX) (X-linked hypophosphatemia protein) (HYP) (Vitamin D-resistant hypophosphatemic rickets protein).
KELL_HUMAN
 
NC score 0.955766 (rank : 12) θ value 1.45253e-74 (rank : 12)
Query Neighborhood Hits 24 Target Neighborhood Hits 18 Shared Neighborhood Hits 12
SwissProt Accessions P23276, Q96RS8, Q99885 Gene names KEL
Domain
Architecture
Description Kell blood group glycoprotein (EC 3.4.24.-) (CD238 antigen).
PSA_MOUSE
 
NC score 0.014469 (rank : 13) θ value 4.03905 (rank : 18)
Query Neighborhood Hits 24 Target Neighborhood Hits 32 Shared Neighborhood Hits 5
SwissProt Accessions Q11011, Q91VJ8 Gene names Npepps, Psa
Domain
Architecture
Description Puromycin-sensitive aminopeptidase (EC 3.4.11.-) (PSA).
PSA_HUMAN
 
NC score 0.014448 (rank : 14) θ value 4.03905 (rank : 17)
Query Neighborhood Hits 24 Target Neighborhood Hits 31 Shared Neighborhood Hits 5
SwissProt Accessions P55786, Q6P145, Q9NP16, Q9UEM2 Gene names NPEPPS, PSA
Domain
Architecture
Description Puromycin-sensitive aminopeptidase (EC 3.4.11.-) (PSA).
AMPE_HUMAN
 
NC score 0.009876 (rank : 15) θ value 8.99809 (rank : 21)
Query Neighborhood Hits 24 Target Neighborhood Hits 46 Shared Neighborhood Hits 5
SwissProt Accessions Q07075 Gene names ENPEP
Domain
Architecture
Description Glutamyl aminopeptidase (EC 3.4.11.7) (EAP) (Aminopeptidase A) (APA) (Differentiation antigen gp160) (CD249 antigen).
SPTB2_HUMAN
 
NC score 0.008382 (rank : 16) θ value 0.813845 (rank : 13)
Query Neighborhood Hits 24 Target Neighborhood Hits 748 Shared Neighborhood Hits 4
SwissProt Accessions Q01082, O60837, Q16057 Gene names SPTBN1, SPTB2
Domain
Architecture
Description Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).
SPTB2_MOUSE
 
NC score 0.008310 (rank : 17) θ value 0.813845 (rank : 14)
Query Neighborhood Hits 24 Target Neighborhood Hits 770 Shared Neighborhood Hits 4
SwissProt Accessions Q62261, Q5SQL8 Gene names Sptbn1, Spnb-2, Spnb2, Sptb2
Domain
Architecture
Description Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).
MKS3_MOUSE
 
NC score 0.007088 (rank : 18) θ value 8.99809 (rank : 23)
Query Neighborhood Hits 24 Target Neighborhood Hits 89 Shared Neighborhood Hits 3
SwissProt Accessions Q8BR76, Q78U07 Gene names Tmem67, Mks3
Domain
Architecture

No domain graphic available

Description Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).
ITIH2_MOUSE
 
NC score 0.006885 (rank : 19) θ value 8.99809 (rank : 22)
Query Neighborhood Hits 24 Target Neighborhood Hits 27 Shared Neighborhood Hits 3
SwissProt Accessions Q61703 Gene names Itih2
Domain
Architecture
Description Inter-alpha-trypsin inhibitor heavy chain H2 precursor (ITI heavy chain H2) (Inter-alpha-inhibitor heavy chain 2).
UBP40_HUMAN
 
NC score 0.004395 (rank : 20) θ value 8.99809 (rank : 24)
Query Neighborhood Hits 24 Target Neighborhood Hits 81 Shared Neighborhood Hits 2
SwissProt Accessions Q9NVE5, Q6NX38, Q70EL0 Gene names USP40
Domain
Architecture

No domain graphic available

Description Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).
LAMB2_MOUSE
 
NC score 0.003466 (rank : 21) θ value 2.36792 (rank : 16)
Query Neighborhood Hits 24 Target Neighborhood Hits 722 Shared Neighborhood Hits 5
SwissProt Accessions Q61292, Q62182 Gene names Lamb2, Lams
Domain
Architecture
Description Laminin beta-2 chain precursor (S-laminin) (S-LAM).
2DOB_HUMAN
 
NC score 0.000987 (rank : 22) θ value 8.99809 (rank : 20)
Query Neighborhood Hits 24 Target Neighborhood Hits 201 Shared Neighborhood Hits 2
SwissProt Accessions P13765, Q29746, Q29825 Gene names HLA-DOB
Domain
Architecture
Description HLA class II histocompatibility antigen, DO beta chain precursor (MHC class II antigen DOB).
SDK1_MOUSE
 
NC score 0.000591 (rank : 23) θ value 6.88961 (rank : 19)
Query Neighborhood Hits 24 Target Neighborhood Hits 495 Shared Neighborhood Hits 2
SwissProt Accessions Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1 Gene names Sdk1
Domain
Architecture

No domain graphic available

Description Protein sidekick-1 precursor.
ZN192_HUMAN
 
NC score -0.001303 (rank : 24) θ value 1.38821 (rank : 15)
Query Neighborhood Hits 24 Target Neighborhood Hits 789 Shared Neighborhood Hits 2
SwissProt Accessions Q15776, Q4VAR1, Q4VAR2, Q4VAR3, Q9H4T1 Gene names ZNF192
Domain
Architecture
Description Zinc finger protein 192 (LD5-1).