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Network neighborhood for query Sequence : CREM_HUMAN

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CREM_HUMAN
SwissProt Accessions	Q03060, Q16114, Q16116, Q9NZB9	Gene names	CREM
Domain Architecture
Description	cAMP-responsive element modulator.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CREM_HUMAN
θ value	1.72687e-168 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	Q03060, Q16114, Q16116, Q9NZB9	Gene names	CREM
Domain Architecture
Description	cAMP-responsive element modulator.

CREM_MOUSE
θ value	5.40562e-146 (rank : 2)	NC score	0.995098 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	58	Shared Neighborhood Hits	49
SwissProt Accessions	P27699, P27698	Gene names	Crem
Domain Architecture
Description	cAMP-responsive element modulator.

CREB1_HUMAN
θ value	4.35321e-87 (rank : 3)	NC score	0.973386 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	57	Shared Neighborhood Hits	30
SwissProt Accessions	P16220, P21934, Q9UMA7	Gene names	CREB1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

CREB1_MOUSE
θ value	9.69798e-87 (rank : 4)	NC score	0.973224 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	58	Shared Neighborhood Hits	30
SwissProt Accessions	Q01147	Gene names	Creb1, Creb-1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

ATF1_HUMAN
θ value	3.36421e-55 (rank : 5)	NC score	0.947111 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	59	Shared Neighborhood Hits	29
SwissProt Accessions	P18846, P25168	Gene names	ATF1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TREB36 protein).

ATF1_MOUSE
θ value	7.25919e-50 (rank : 6)	NC score	0.941856 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	P81269	Gene names	Atf1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TCR-ATF1).

ATF6A_HUMAN
θ value	6.43352e-06 (rank : 7)	NC score	0.398879 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	174	Shared Neighborhood Hits	32
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

ATF6B_HUMAN
θ value	4.1701e-05 (rank : 8)	NC score	0.335952 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	122	Shared Neighborhood Hits	19
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

CREB3_MOUSE
θ value	0.000121331 (rank : 9)	NC score	0.398522 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	97	Shared Neighborhood Hits	32
SwissProt Accessions	Q61817, Q99M21, Q9CVK9	Gene names	Creb3, Lzip
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Transcription factor LZIP).

ATF6B_MOUSE
θ value	0.00020696 (rank : 10)	NC score	0.328112 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	97	Shared Neighborhood Hits	18
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

CREB3_HUMAN
θ value	0.00035302 (rank : 11)	NC score	0.387853 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	138	Shared Neighborhood Hits	31
SwissProt Accessions	O43889, O14671, O14919, Q96GK8, Q9H2W3, Q9UE77	Gene names	CREB3, LZIP
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Luman protein) (Transcription factor LZIP-alpha).

JUN_HUMAN
θ value	0.000461057 (rank : 12)	NC score	0.320427 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	144	Shared Neighborhood Hits	30
SwissProt Accessions	P05412, Q96G93	Gene names	JUN
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39).

JUN_MOUSE
θ value	0.000461057 (rank : 13)	NC score	0.320879 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	145	Shared Neighborhood Hits	30
SwissProt Accessions	P05627	Gene names	Jun
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (Jun A) (AH119).

JUND_HUMAN
θ value	0.00298849 (rank : 14)	NC score	0.317931 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	122	Shared Neighborhood Hits	31
SwissProt Accessions	P17535	Gene names	JUND
Domain Architecture
Description	Transcription factor jun-D.

JUND_MOUSE
θ value	0.00298849 (rank : 15)	NC score	0.312804 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	134	Shared Neighborhood Hits	32
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

ATF7_HUMAN
θ value	0.0193708 (rank : 16)	NC score	0.249659 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	333	Shared Neighborhood Hits	32
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ATF7_MOUSE
θ value	0.0193708 (rank : 17)	NC score	0.252780 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	286	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

JUNB_HUMAN
θ value	0.0193708 (rank : 18)	NC score	0.290703 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	97	Shared Neighborhood Hits	32
SwissProt Accessions	P17275, Q96GH3	Gene names	JUNB
Domain Architecture
Description	Transcription factor jun-B.

JUNB_MOUSE
θ value	0.0193708 (rank : 19)	NC score	0.287093 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	116	Shared Neighborhood Hits	33
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

PGCA_MOUSE
θ value	0.0252991 (rank : 20)	NC score	0.029714 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	643	Shared Neighborhood Hits	12
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

ATF2_HUMAN
θ value	0.0563607 (rank : 21)	NC score	0.219105 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	402	Shared Neighborhood Hits	34
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
θ value	0.0563607 (rank : 22)	NC score	0.218919 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	397	Shared Neighborhood Hits	34
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

BACH2_HUMAN
θ value	0.0736092 (rank : 23)	NC score	0.095755 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	234	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYV9, Q59H70, Q5T793, Q9NTS5	Gene names	BACH2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

BACH2_MOUSE
θ value	0.0961366 (rank : 24)	NC score	0.093949 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	248	Shared Neighborhood Hits	28
SwissProt Accessions	P97303	Gene names	Bach2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

BACH1_HUMAN
θ value	0.125558 (rank : 25)	NC score	0.109540 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	289	Shared Neighborhood Hits	29
SwissProt Accessions	O14867, O43285	Gene names	BACH1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303).

BACH1_MOUSE
θ value	0.125558 (rank : 26)	NC score	0.108459 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	289	Shared Neighborhood Hits	29
SwissProt Accessions	P97302	Gene names	Bach1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1).

CREB5_HUMAN
θ value	0.365318 (rank : 27)	NC score	0.234977 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	222	Shared Neighborhood Hits	30
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

TPR_HUMAN
θ value	0.365318 (rank : 28)	NC score	0.016465 (rank : 70)
Query Neighborhood Hits	63	Target Neighborhood Hits	1921	Shared Neighborhood Hits	22
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

EP400_HUMAN
θ value	0.47712 (rank : 29)	NC score	0.027156 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	556	Shared Neighborhood Hits	9
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

ARMX2_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.028813 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

BAP29_HUMAN
θ value	1.38821 (rank : 31)	NC score	0.033505 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	362	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHQ4, O95003	Gene names	BCAP29, BAP29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

SFRIP_HUMAN
θ value	1.38821 (rank : 32)	NC score	0.028673 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	530	Shared Neighborhood Hits	8
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

EMSY_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.026492 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	296	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

SLC2B_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.032716 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

UTRO_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.014071 (rank : 73)
Query Neighborhood Hits	63	Target Neighborhood Hits	960	Shared Neighborhood Hits	9
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

NF2L2_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.089041 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	183	Shared Neighborhood Hits	23
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

RUFY2_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.016951 (rank : 68)
Query Neighborhood Hits	63	Target Neighborhood Hits	820	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

ATF3_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.161538 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	P18847	Gene names	ATF3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3).

ATF3_MOUSE
θ value	3.0926 (rank : 39)	NC score	0.157877 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	Q60765	Gene names	Atf3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3) (Transcription factor LRG-21).

PUM2_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.021836 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TB72, O00234, Q53TV7, Q8WY43, Q9HAN2	Gene names	PUM2, KIAA0235, PUMH2
Domain Architecture
Description	Pumilio homolog 2 (Pumilio-2).

RING1_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.039253 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	219	Shared Neighborhood Hits	6
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.039406 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	220	Shared Neighborhood Hits	6
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

NU214_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.019309 (rank : 64)
Query Neighborhood Hits	63	Target Neighborhood Hits	657	Shared Neighborhood Hits	10
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

NUPL_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.019335 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

PUM2_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.021670 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q80U58, Q80UZ9, Q91YW4, Q925A0, Q9ERC7	Gene names	Pum2, Kiaa0235
Domain Architecture
Description	Pumilio homolog 2.

RUFY2_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.012495 (rank : 74)
Query Neighborhood Hits	63	Target Neighborhood Hits	1208	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

K0240_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.019102 (rank : 65)
Query Neighborhood Hits	63	Target Neighborhood Hits	211	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

NFRKB_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.040077 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	211	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

RING2_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.031826 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	201	Shared Neighborhood Hits	6
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.031827 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	199	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

S25BP_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.030346 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	O95295	Gene names	SNAPAP, SNAP25BP
Domain Architecture	No domain graphic available
Description	SNARE-associated protein Snapin (Synaptosomal-associated protein 25- binding protein) (SNAP-associated protein).

SYNE1_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.010379 (rank : 76)
Query Neighborhood Hits	63	Target Neighborhood Hits	1484	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

GSCR1_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.015336 (rank : 72)
Query Neighborhood Hits	63	Target Neighborhood Hits	674	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HGS_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.016502 (rank : 69)
Query Neighborhood Hits	63	Target Neighborhood Hits	589	Shared Neighborhood Hits	9
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

NF2L1_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.074540 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	169	Shared Neighborhood Hits	25
SwissProt Accessions	Q14494, Q12877, Q96FN6	Gene names	NFE2L1, HBZ17, NRF1, TCF11
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Transcription factor 11) (Transcription factor HBZ17) (Transcription factor LCR-F1) (Locus control region-factor 1).

NF2L1_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.075498 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	185	Shared Neighborhood Hits	25
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

PGCA_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.016420 (rank : 71)
Query Neighborhood Hits	63	Target Neighborhood Hits	821	Shared Neighborhood Hits	7
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

CROCC_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.006815 (rank : 78)
Query Neighborhood Hits	63	Target Neighborhood Hits	1460	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

EPN1_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.011199 (rank : 75)
Query Neighborhood Hits	63	Target Neighborhood Hits	240	Shared Neighborhood Hits	6
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

NUPL_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.017888 (rank : 67)
Query Neighborhood Hits	63	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

PCQAP_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.017907 (rank : 66)
Query Neighborhood Hits	63	Target Neighborhood Hits	549	Shared Neighborhood Hits	14
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PEPL_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.007844 (rank : 77)
Query Neighborhood Hits	63	Target Neighborhood Hits	1105	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

TEX14_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.000787 (rank : 79)
Query Neighborhood Hits	63	Target Neighborhood Hits	1333	Shared Neighborhood Hits	8
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

BATF_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.069460 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	80	Shared Neighborhood Hits	22
SwissProt Accessions	Q16520	Gene names	BATF
Domain Architecture
Description	ATF-like basic leucine zipper transcriptional factor B-ATF (SF-HT- activated gene 2) (SFA-2).

BATF_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.065532 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	100	Shared Neighborhood Hits	24
SwissProt Accessions	O35284	Gene names	Batf
Domain Architecture
Description	ATF-like basic leucine zipper transcription factor B-ATF.

FOSB_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.061508 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	P53539	Gene names	FOSB, G0S3
Domain Architecture	No domain graphic available
Description	Protein fosB (G0/G1 switch regulatory protein 3).

FOSB_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.063832 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	137	Shared Neighborhood Hits	23
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

FOSL1_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.056973 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	112	Shared Neighborhood Hits	21
SwissProt Accessions	P15407	Gene names	FOSL1, FRA1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

FOSL1_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.059770 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	113	Shared Neighborhood Hits	20
SwissProt Accessions	P48755, O35285	Gene names	Fosl1, Fra1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

FOSL2_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.052778 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	158	Shared Neighborhood Hits	19
SwissProt Accessions	P15408	Gene names	FOSL2, FRA2
Domain Architecture	No domain graphic available
Description	Fos-related antigen 2.

NF2L2_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.063083 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	109	Shared Neighborhood Hits	17
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

NF2L3_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.071793 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	150	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

NF2L3_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.063140 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	93	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

NFE2_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.079075 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	66	Shared Neighborhood Hits	17
SwissProt Accessions	Q16621, Q07720, Q6ICV9	Gene names	NFE2
Domain Architecture	No domain graphic available
Description	Transcription factor NF-E2 45 kDa subunit (Nuclear factor, erythroid- derived 2 45 kDa subunit) (p45 NF-E2) (Leucine zipper protein NF-E2).

NFRKB_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.054525 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	393	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NFYA_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.075891 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	P23511, Q8IXU0	Gene names	NFYA
Domain Architecture
Description	Nuclear transcription factor Y subunit alpha (Nuclear transcription factor Y subunit A) (NF-YA) (CAAT-box DNA-binding protein subunit A).

NFYA_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.075826 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	P23708	Gene names	Nfya
Domain Architecture
Description	Nuclear transcription factor Y subunit alpha (Nuclear transcription factor Y subunit A) (NF-YA) (CAAT-box DNA-binding protein subunit A).

XBP1_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.075108 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	P17861, Q8WYK6, Q969P1, Q96BD7	Gene names	XBP1, TREB5, XBP2
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5).

XBP1_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.084867 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	O35426, Q8VHM0, Q922G5, Q9ESS3	Gene names	Xbp1, Treb5
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5 homolog).

Hits sorted by NC score

CREM_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.72687e-168 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	Q03060, Q16114, Q16116, Q9NZB9	Gene names	CREM
Domain Architecture
Description	cAMP-responsive element modulator.

CREM_MOUSE
NC score	0.995098 (rank : 2)	θ value	5.40562e-146 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	58	Shared Neighborhood Hits	49
SwissProt Accessions	P27699, P27698	Gene names	Crem
Domain Architecture
Description	cAMP-responsive element modulator.

CREB1_HUMAN
NC score	0.973386 (rank : 3)	θ value	4.35321e-87 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	57	Shared Neighborhood Hits	30
SwissProt Accessions	P16220, P21934, Q9UMA7	Gene names	CREB1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

CREB1_MOUSE
NC score	0.973224 (rank : 4)	θ value	9.69798e-87 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	58	Shared Neighborhood Hits	30
SwissProt Accessions	Q01147	Gene names	Creb1, Creb-1
Domain Architecture
Description	cAMP response element-binding protein (CREB).

ATF1_HUMAN
NC score	0.947111 (rank : 5)	θ value	3.36421e-55 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	59	Shared Neighborhood Hits	29
SwissProt Accessions	P18846, P25168	Gene names	ATF1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TREB36 protein).

ATF1_MOUSE
NC score	0.941856 (rank : 6)	θ value	7.25919e-50 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	70	Shared Neighborhood Hits	30
SwissProt Accessions	P81269	Gene names	Atf1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-1 (Activating transcription factor 1) (TCR-ATF1).

ATF6A_HUMAN
NC score	0.398879 (rank : 7)	θ value	6.43352e-06 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	174	Shared Neighborhood Hits	32
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

CREB3_MOUSE
NC score	0.398522 (rank : 8)	θ value	0.000121331 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	97	Shared Neighborhood Hits	32
SwissProt Accessions	Q61817, Q99M21, Q9CVK9	Gene names	Creb3, Lzip
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Transcription factor LZIP).

CREB3_HUMAN
NC score	0.387853 (rank : 9)	θ value	0.00035302 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	138	Shared Neighborhood Hits	31
SwissProt Accessions	O43889, O14671, O14919, Q96GK8, Q9H2W3, Q9UE77	Gene names	CREB3, LZIP
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Luman protein) (Transcription factor LZIP-alpha).

ATF6B_HUMAN
NC score	0.335952 (rank : 10)	θ value	4.1701e-05 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	122	Shared Neighborhood Hits	19
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

ATF6B_MOUSE
NC score	0.328112 (rank : 11)	θ value	0.00020696 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	97	Shared Neighborhood Hits	18
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

JUN_MOUSE
NC score	0.320879 (rank : 12)	θ value	0.000461057 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	145	Shared Neighborhood Hits	30
SwissProt Accessions	P05627	Gene names	Jun
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (Jun A) (AH119).

JUN_HUMAN
NC score	0.320427 (rank : 13)	θ value	0.000461057 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	144	Shared Neighborhood Hits	30
SwissProt Accessions	P05412, Q96G93	Gene names	JUN
Domain Architecture
Description	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39).

JUND_HUMAN
NC score	0.317931 (rank : 14)	θ value	0.00298849 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	122	Shared Neighborhood Hits	31
SwissProt Accessions	P17535	Gene names	JUND
Domain Architecture
Description	Transcription factor jun-D.

JUND_MOUSE
NC score	0.312804 (rank : 15)	θ value	0.00298849 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	134	Shared Neighborhood Hits	32
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

JUNB_HUMAN
NC score	0.290703 (rank : 16)	θ value	0.0193708 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	97	Shared Neighborhood Hits	32
SwissProt Accessions	P17275, Q96GH3	Gene names	JUNB
Domain Architecture
Description	Transcription factor jun-B.

JUNB_MOUSE
NC score	0.287093 (rank : 17)	θ value	0.0193708 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	116	Shared Neighborhood Hits	33
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

ATF7_MOUSE
NC score	0.252780 (rank : 18)	θ value	0.0193708 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	286	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ATF7_HUMAN
NC score	0.249659 (rank : 19)	θ value	0.0193708 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	333	Shared Neighborhood Hits	32
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

CREB5_HUMAN
NC score	0.234977 (rank : 20)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	222	Shared Neighborhood Hits	30
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

ATF2_HUMAN
NC score	0.219105 (rank : 21)	θ value	0.0563607 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	402	Shared Neighborhood Hits	34
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
NC score	0.218919 (rank : 22)	θ value	0.0563607 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	397	Shared Neighborhood Hits	34
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

ATF3_HUMAN
NC score	0.161538 (rank : 23)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	P18847	Gene names	ATF3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3).

ATF3_MOUSE
NC score	0.157877 (rank : 24)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	Q60765	Gene names	Atf3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3) (Transcription factor LRG-21).

BACH1_HUMAN
NC score	0.109540 (rank : 25)	θ value	0.125558 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	289	Shared Neighborhood Hits	29
SwissProt Accessions	O14867, O43285	Gene names	BACH1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303).

BACH1_MOUSE
NC score	0.108459 (rank : 26)	θ value	0.125558 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	289	Shared Neighborhood Hits	29
SwissProt Accessions	P97302	Gene names	Bach1
Domain Architecture
Description	Transcription regulator protein BACH1 (BTB and CNC homolog 1).

BACH2_HUMAN
NC score	0.095755 (rank : 27)	θ value	0.0736092 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	234	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYV9, Q59H70, Q5T793, Q9NTS5	Gene names	BACH2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

BACH2_MOUSE
NC score	0.093949 (rank : 28)	θ value	0.0961366 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	248	Shared Neighborhood Hits	28
SwissProt Accessions	P97303	Gene names	Bach2
Domain Architecture
Description	Transcription regulator protein BACH2 (BTB and CNC homolog 2).

NF2L2_MOUSE
NC score	0.089041 (rank : 29)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	183	Shared Neighborhood Hits	23
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

XBP1_MOUSE
NC score	0.084867 (rank : 30)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	63	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	O35426, Q8VHM0, Q922G5, Q9ESS3	Gene names	Xbp1, Treb5
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5 homolog).

NFE2_HUMAN
NC score	0.079075 (rank : 31)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	63	Target Neighborhood Hits	66	Shared Neighborhood Hits	17
SwissProt Accessions	Q16621, Q07720, Q6ICV9	Gene names	NFE2
Domain Architecture	No domain graphic available
Description	Transcription factor NF-E2 45 kDa subunit (Nuclear factor, erythroid- derived 2 45 kDa subunit) (p45 NF-E2) (Leucine zipper protein NF-E2).

NFYA_HUMAN
NC score	0.075891 (rank : 32)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	63	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	P23511, Q8IXU0	Gene names	NFYA
Domain Architecture
Description	Nuclear transcription factor Y subunit alpha (Nuclear transcription factor Y subunit A) (NF-YA) (CAAT-box DNA-binding protein subunit A).

NFYA_MOUSE
NC score	0.075826 (rank : 33)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	63	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	P23708	Gene names	Nfya
Domain Architecture
Description	Nuclear transcription factor Y subunit alpha (Nuclear transcription factor Y subunit A) (NF-YA) (CAAT-box DNA-binding protein subunit A).

NF2L1_MOUSE
NC score	0.075498 (rank : 34)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	185	Shared Neighborhood Hits	25
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

XBP1_HUMAN
NC score	0.075108 (rank : 35)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	63	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	P17861, Q8WYK6, Q969P1, Q96BD7	Gene names	XBP1, TREB5, XBP2
Domain Architecture	No domain graphic available
Description	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5).

NF2L1_HUMAN
NC score	0.074540 (rank : 36)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	169	Shared Neighborhood Hits	25
SwissProt Accessions	Q14494, Q12877, Q96FN6	Gene names	NFE2L1, HBZ17, NRF1, TCF11
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Transcription factor 11) (Transcription factor HBZ17) (Transcription factor LCR-F1) (Locus control region-factor 1).

NF2L3_HUMAN
NC score	0.071793 (rank : 37)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	63	Target Neighborhood Hits	150	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

BATF_HUMAN
NC score	0.069460 (rank : 38)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	63	Target Neighborhood Hits	80	Shared Neighborhood Hits	22
SwissProt Accessions	Q16520	Gene names	BATF
Domain Architecture
Description	ATF-like basic leucine zipper transcriptional factor B-ATF (SF-HT- activated gene 2) (SFA-2).

BATF_MOUSE
NC score	0.065532 (rank : 39)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	63	Target Neighborhood Hits	100	Shared Neighborhood Hits	24
SwissProt Accessions	O35284	Gene names	Batf
Domain Architecture
Description	ATF-like basic leucine zipper transcription factor B-ATF.

FOSB_MOUSE
NC score	0.063832 (rank : 40)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	63	Target Neighborhood Hits	137	Shared Neighborhood Hits	23
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

NF2L3_MOUSE
NC score	0.063140 (rank : 41)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	63	Target Neighborhood Hits	93	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

NF2L2_HUMAN
NC score	0.063083 (rank : 42)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	63	Target Neighborhood Hits	109	Shared Neighborhood Hits	17
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

FOSB_HUMAN
NC score	0.061508 (rank : 43)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	63	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	P53539	Gene names	FOSB, G0S3
Domain Architecture	No domain graphic available
Description	Protein fosB (G0/G1 switch regulatory protein 3).

FOSL1_MOUSE
NC score	0.059770 (rank : 44)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	63	Target Neighborhood Hits	113	Shared Neighborhood Hits	20
SwissProt Accessions	P48755, O35285	Gene names	Fosl1, Fra1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

FOSL1_HUMAN
NC score	0.056973 (rank : 45)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	63	Target Neighborhood Hits	112	Shared Neighborhood Hits	21
SwissProt Accessions	P15407	Gene names	FOSL1, FRA1
Domain Architecture
Description	Fos-related antigen 1 (FRA-1).

NFRKB_MOUSE
NC score	0.054525 (rank : 46)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	63	Target Neighborhood Hits	393	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

FOSL2_HUMAN
NC score	0.052778 (rank : 47)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	63	Target Neighborhood Hits	158	Shared Neighborhood Hits	19
SwissProt Accessions	P15408	Gene names	FOSL2, FRA2
Domain Architecture	No domain graphic available
Description	Fos-related antigen 2.

NFRKB_HUMAN
NC score	0.040077 (rank : 48)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	211	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

RING1_MOUSE
NC score	0.039406 (rank : 49)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	220	Shared Neighborhood Hits	6
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING1_HUMAN
NC score	0.039253 (rank : 50)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	219	Shared Neighborhood Hits	6
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

BAP29_HUMAN
NC score	0.033505 (rank : 51)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	362	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHQ4, O95003	Gene names	BCAP29, BAP29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

SLC2B_HUMAN
NC score	0.032716 (rank : 52)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

RING2_MOUSE
NC score	0.031827 (rank : 53)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	199	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RING2_HUMAN
NC score	0.031826 (rank : 54)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	201	Shared Neighborhood Hits	6
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

S25BP_HUMAN
NC score	0.030346 (rank : 55)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	O95295	Gene names	SNAPAP, SNAP25BP
Domain Architecture	No domain graphic available
Description	SNARE-associated protein Snapin (Synaptosomal-associated protein 25- binding protein) (SNAP-associated protein).

PGCA_MOUSE
NC score	0.029714 (rank : 56)	θ value	0.0252991 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	643	Shared Neighborhood Hits	12
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

ARMX2_HUMAN
NC score	0.028813 (rank : 57)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

SFRIP_HUMAN
NC score	0.028673 (rank : 58)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	530	Shared Neighborhood Hits	8
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

EP400_HUMAN
NC score	0.027156 (rank : 59)	θ value	0.47712 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	556	Shared Neighborhood Hits	9
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EMSY_HUMAN
NC score	0.026492 (rank : 60)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	296	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

PUM2_HUMAN
NC score	0.021836 (rank : 61)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TB72, O00234, Q53TV7, Q8WY43, Q9HAN2	Gene names	PUM2, KIAA0235, PUMH2
Domain Architecture
Description	Pumilio homolog 2 (Pumilio-2).

PUM2_MOUSE
NC score	0.021670 (rank : 62)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q80U58, Q80UZ9, Q91YW4, Q925A0, Q9ERC7	Gene names	Pum2, Kiaa0235
Domain Architecture
Description	Pumilio homolog 2.

NUPL_HUMAN
NC score	0.019335 (rank : 63)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

NU214_HUMAN
NC score	0.019309 (rank : 64)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	657	Shared Neighborhood Hits	10
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

K0240_MOUSE
NC score	0.019102 (rank : 65)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	211	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

PCQAP_HUMAN
NC score	0.017907 (rank : 66)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	549	Shared Neighborhood Hits	14
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

NUPL_MOUSE
NC score	0.017888 (rank : 67)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

RUFY2_MOUSE
NC score	0.016951 (rank : 68)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	820	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

HGS_MOUSE
NC score	0.016502 (rank : 69)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	589	Shared Neighborhood Hits	9
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

TPR_HUMAN
NC score	0.016465 (rank : 70)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	1921	Shared Neighborhood Hits	22
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

PGCA_HUMAN
NC score	0.016420 (rank : 71)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	821	Shared Neighborhood Hits	7
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

GSCR1_HUMAN
NC score	0.015336 (rank : 72)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	674	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

UTRO_HUMAN
NC score	0.014071 (rank : 73)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	960	Shared Neighborhood Hits	9
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

RUFY2_HUMAN
NC score	0.012495 (rank : 74)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	1208	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

EPN1_MOUSE
NC score	0.011199 (rank : 75)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	240	Shared Neighborhood Hits	6
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

SYNE1_HUMAN
NC score	0.010379 (rank : 76)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	1484	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

PEPL_MOUSE
NC score	0.007844 (rank : 77)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	1105	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

CROCC_MOUSE
NC score	0.006815 (rank : 78)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	1460	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

TEX14_MOUSE
NC score	0.000787 (rank : 79)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	1333	Shared Neighborhood Hits	8
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).