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Network neighborhood for query Sequence : UBR1_MOUSE

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UBR1_MOUSE
SwissProt Accessions	O70481, Q5BKR8, Q792M3, Q8BN40, Q8C5K3	Gene names	Ubr1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBR1_HUMAN
θ value	0 (rank : 1)	NC score	0.997177 (rank : 2)
Query Neighborhood Hits	52	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IWV7, O60708, O75492, Q68DN9, Q8IWY6, Q96JY4	Gene names	UBR1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

UBR1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	52	Target Neighborhood Hits	52	Shared Neighborhood Hits	52
SwissProt Accessions	O70481, Q5BKR8, Q792M3, Q8BN40, Q8C5K3	Gene names	Ubr1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

UBR2_HUMAN
θ value	0 (rank : 3)	NC score	0.978723 (rank : 4)
Query Neighborhood Hits	52	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IWV8, O15057, Q4VXK2, Q5TFH6, Q6P2I2, Q6ZUD0	Gene names	UBR2, C6orf133, KIAA0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

UBR2_MOUSE
θ value	0 (rank : 4)	NC score	0.979388 (rank : 3)
Query Neighborhood Hits	52	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q6WKZ8, Q6DIB9, Q80U31, Q8BUL9, Q8CGW0, Q8K2I6, Q8R0V7, Q8R130	Gene names	Ubr2, Kiaa0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

JAK2_HUMAN
θ value	0.0736092 (rank : 5)	NC score	0.014987 (rank : 15)
Query Neighborhood Hits	52	Target Neighborhood Hits	847	Shared Neighborhood Hits	7
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

STX1A_HUMAN
θ value	0.0961366 (rank : 6)	NC score	0.022611 (rank : 10)
Query Neighborhood Hits	52	Target Neighborhood Hits	266	Shared Neighborhood Hits	5
SwissProt Accessions	Q16623, O15447, O15448, Q12936, Q9BPZ6	Gene names	STX1A, STX1
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

JAK2_MOUSE
θ value	0.21417 (rank : 7)	NC score	0.013769 (rank : 19)
Query Neighborhood Hits	52	Target Neighborhood Hits	839	Shared Neighborhood Hits	7
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

ZN578_HUMAN
θ value	0.365318 (rank : 8)	NC score	0.009380 (rank : 28)
Query Neighborhood Hits	52	Target Neighborhood Hits	755	Shared Neighborhood Hits	17
SwissProt Accessions	Q96N58	Gene names	ZNF578
Domain Architecture	No domain graphic available
Description	Zinc finger protein 578.

ZN283_HUMAN
θ value	0.47712 (rank : 9)	NC score	0.009231 (rank : 29)
Query Neighborhood Hits	52	Target Neighborhood Hits	760	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N7M2	Gene names	ZNF283
Domain Architecture	No domain graphic available
Description	Zinc finger protein 283.

COPA_HUMAN
θ value	1.38821 (rank : 10)	NC score	0.013803 (rank : 18)
Query Neighborhood Hits	52	Target Neighborhood Hits	297	Shared Neighborhood Hits	3
SwissProt Accessions	P53621	Gene names	COPA
Domain Architecture
Description	Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEPCOP) (HEP- COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin].

EDD1_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.036873 (rank : 8)
Query Neighborhood Hits	52	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

EDD1_MOUSE
θ value	1.38821 (rank : 12)	NC score	0.036877 (rank : 7)
Query Neighborhood Hits	52	Target Neighborhood Hits	167	Shared Neighborhood Hits	7
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

ZN236_HUMAN
θ value	1.38821 (rank : 13)	NC score	0.009666 (rank : 27)
Query Neighborhood Hits	52	Target Neighborhood Hits	844	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UL36, Q9UL37	Gene names	ZNF236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 236.

FARP1_HUMAN
θ value	1.81305 (rank : 14)	NC score	0.008095 (rank : 34)
Query Neighborhood Hits	52	Target Neighborhood Hits	241	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

UBP34_MOUSE
θ value	1.81305 (rank : 15)	NC score	0.016558 (rank : 13)
Query Neighborhood Hits	52	Target Neighborhood Hits	189	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

ZN583_MOUSE
θ value	1.81305 (rank : 16)	NC score	0.009142 (rank : 30)
Query Neighborhood Hits	52	Target Neighborhood Hits	774	Shared Neighborhood Hits	17
SwissProt Accessions	Q3V080, Q3V3L4	Gene names	Znf583, Zfp583
Domain Architecture	No domain graphic available
Description	Zinc finger protein 583.

ZN417_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.007509 (rank : 36)
Query Neighborhood Hits	52	Target Neighborhood Hits	753	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TAU3	Gene names	ZNF417
Domain Architecture	No domain graphic available
Description	Zinc finger protein 417.

EDG4_MOUSE
θ value	3.0926 (rank : 18)	NC score	0.011122 (rank : 24)
Query Neighborhood Hits	52	Target Neighborhood Hits	461	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JL06	Gene names	Edg4, Lpa2
Domain Architecture
Description	Lysophosphatidic acid receptor Edg-4 (LPA receptor 2) (LPA-2).

PTN2_HUMAN
θ value	3.0926 (rank : 19)	NC score	0.005989 (rank : 47)
Query Neighborhood Hits	52	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

RYR3_HUMAN
θ value	3.0926 (rank : 20)	NC score	0.016491 (rank : 14)
Query Neighborhood Hits	52	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

FANCL_HUMAN
θ value	4.03905 (rank : 21)	NC score	0.018990 (rank : 12)
Query Neighborhood Hits	52	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NW38	Gene names	FANCL, PHF9
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein FANCL (EC 6.3.2.-) (Fanconi anemia group L protein) (Fanconi anemia-associated polypeptide of 43 kDa) (FAAP43).

IRX4_MOUSE
θ value	4.03905 (rank : 22)	NC score	0.012150 (rank : 22)
Query Neighborhood Hits	52	Target Neighborhood Hits	286	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QY61	Gene names	Irx4, Irxa3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein 4) (Homeodomain protein IRXA3).

LMNB2_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.003773 (rank : 49)
Query Neighborhood Hits	52	Target Neighborhood Hits	674	Shared Neighborhood Hits	5
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

MD2L1_MOUSE
θ value	4.03905 (rank : 24)	NC score	0.020639 (rank : 11)
Query Neighborhood Hits	52	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1B5, Q9JI53	Gene names	Mad2l1, Mad2a
Domain Architecture
Description	Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1).

PP1R8_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.037880 (rank : 5)
Query Neighborhood Hits	52	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q12972, Q5TIF2, Q6PKF6, Q9UBH1, Q9UBZ0	Gene names	PPP1R8, ARD1, NIPP1
Domain Architecture
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator of RNA decay (EC 3.1.4.-) (ARD-1)].

PP1R8_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.037857 (rank : 6)
Query Neighborhood Hits	52	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3G1, Q8C087	Gene names	Ppp1r8, Nipp1
Domain Architecture	No domain graphic available
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8).

SYNE1_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.006657 (rank : 42)
Query Neighborhood Hits	52	Target Neighborhood Hits	1484	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

ZN572_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.007797 (rank : 35)
Query Neighborhood Hits	52	Target Neighborhood Hits	754	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z3I7, Q8N1Q0	Gene names	ZNF572
Domain Architecture	No domain graphic available
Description	Zinc finger protein 572.

ZN587_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.007244 (rank : 37)
Query Neighborhood Hits	52	Target Neighborhood Hits	756	Shared Neighborhood Hits	16
SwissProt Accessions	Q96SQ5, Q6ZMK8	Gene names	ZNF587
Domain Architecture	No domain graphic available
Description	Zinc finger protein 587.

DCAK2_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.002597 (rank : 51)
Query Neighborhood Hits	52	Target Neighborhood Hits	862	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N568, Q8N399	Gene names	DCAMKL2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 2).

DCAK2_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.002599 (rank : 50)
Query Neighborhood Hits	52	Target Neighborhood Hits	858	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PGN3, Q8BUU0, Q8BX25	Gene names	Dcamkl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 2).

DYDC2_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.035486 (rank : 9)
Query Neighborhood Hits	52	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q96IM9, Q5QP07, Q5QP11	Gene names	DYDC2
Domain Architecture	No domain graphic available
Description	DPY30 domain-containing protein 2.

RASF8_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.009038 (rank : 31)
Query Neighborhood Hits	52	Target Neighborhood Hits	391	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CJ96, Q8CCW4, Q9CU91	Gene names	Rassf8
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1 homolog).

TAXB1_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.004426 (rank : 48)
Query Neighborhood Hits	52	Target Neighborhood Hits	886	Shared Neighborhood Hits	7
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

TITIN_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.001544 (rank : 52)
Query Neighborhood Hits	52	Target Neighborhood Hits	2923	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TYRO_MOUSE
θ value	5.27518 (rank : 36)	NC score	0.010337 (rank : 26)
Query Neighborhood Hits	52	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P11344	Gene names	Tyr
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Albino locus protein).

ZN583_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.008118 (rank : 32)
Query Neighborhood Hits	52	Target Neighborhood Hits	774	Shared Neighborhood Hits	17
SwissProt Accessions	Q96ND8, O14850, Q2NKK3	Gene names	ZNF583
Domain Architecture	No domain graphic available
Description	Zinc finger protein 583 (Zinc finger protein L3-5).

IFNK_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.014919 (rank : 16)
Query Neighborhood Hits	52	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0W0, Q5T166	Gene names	IFNK
Domain Architecture	No domain graphic available
Description	Interferon kappa precursor (IFN-kappa).

IRX4_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.010456 (rank : 25)
Query Neighborhood Hits	52	Target Neighborhood Hits	276	Shared Neighborhood Hits	3
SwissProt Accessions	P78413, Q9UHR2	Gene names	IRX4, IRXA3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein 4) (Homeodomain protein IRXA3).

NU153_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.011737 (rank : 23)
Query Neighborhood Hits	52	Target Neighborhood Hits	227	Shared Neighborhood Hits	2
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

SP8_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.006226 (rank : 45)
Query Neighborhood Hits	52	Target Neighborhood Hits	714	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IXZ3, Q7Z616, Q96MJ1	Gene names	SP8
Domain Architecture	No domain graphic available
Description	Transcription factor Sp8 (Specificity protein 8).

TSNA1_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.014679 (rank : 17)
Query Neighborhood Hits	52	Target Neighborhood Hits	178	Shared Neighborhood Hits	5
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

ZN527_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.006720 (rank : 40)
Query Neighborhood Hits	52	Target Neighborhood Hits	751	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NB42	Gene names	ZNF527
Domain Architecture	No domain graphic available
Description	Zinc finger protein 527.

ZNF30_HUMAN
θ value	6.88961 (rank : 44)	NC score	0.006795 (rank : 39)
Query Neighborhood Hits	52	Target Neighborhood Hits	750	Shared Neighborhood Hits	16
SwissProt Accessions	P17039, Q6N068	Gene names	ZNF30, KOX28
Domain Architecture	No domain graphic available
Description	Zinc finger protein 30 (Zinc finger protein KOX28).

ZNF91_HUMAN
θ value	6.88961 (rank : 45)	NC score	0.006678 (rank : 41)
Query Neighborhood Hits	52	Target Neighborhood Hits	797	Shared Neighborhood Hits	16
SwissProt Accessions	Q05481	Gene names	ZNF91
Domain Architecture
Description	Zinc finger protein 91 (Zinc finger protein HTF10) (HPF7).

DEST_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.008102 (rank : 33)
Query Neighborhood Hits	52	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0P5	Gene names	Dstn, Dsn, Sid23
Domain Architecture
Description	Destrin (Actin-depolymerizing factor) (ADF) (Sid 23).

HKR1_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.007053 (rank : 38)
Query Neighborhood Hits	52	Target Neighborhood Hits	759	Shared Neighborhood Hits	17
SwissProt Accessions	P10072, Q9BSW9, Q9UM09	Gene names	HKR1
Domain Architecture
Description	Krueppel-related zinc finger protein 1 (Protein HKR1).

P66B_HUMAN
θ value	8.99809 (rank : 48)	NC score	0.012491 (rank : 21)
Query Neighborhood Hits	52	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXI9, Q7LG68, Q9ULS0	Gene names	GATAD2B, KIAA1150
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger domain- containing protein 2B).

P66B_MOUSE
θ value	8.99809 (rank : 49)	NC score	0.012502 (rank : 20)
Query Neighborhood Hits	52	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHR5, Q8C9Q3	Gene names	Gatad2b
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger domain- containing protein 2B).

ZFY16_MOUSE
θ value	8.99809 (rank : 50)	NC score	0.006114 (rank : 46)
Query Neighborhood Hits	52	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

ZN345_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.006608 (rank : 44)
Query Neighborhood Hits	52	Target Neighborhood Hits	748	Shared Neighborhood Hits	16
SwissProt Accessions	Q14585	Gene names	ZNF345
Domain Architecture	No domain graphic available
Description	Zinc finger protein 345 (Zinc finger protein HZF10).

ZN546_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.006655 (rank : 43)
Query Neighborhood Hits	52	Target Neighborhood Hits	772	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UE3	Gene names	ZNF546, ZNF49
Domain Architecture	No domain graphic available
Description	Zinc finger protein 546.

Hits sorted by NC score

UBR1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	52	Target Neighborhood Hits	52	Shared Neighborhood Hits	52
SwissProt Accessions	O70481, Q5BKR8, Q792M3, Q8BN40, Q8C5K3	Gene names	Ubr1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

UBR1_HUMAN
NC score	0.997177 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	52	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IWV7, O60708, O75492, Q68DN9, Q8IWY6, Q96JY4	Gene names	UBR1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-1 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3- alpha-I).

UBR2_MOUSE
NC score	0.979388 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	52	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q6WKZ8, Q6DIB9, Q80U31, Q8BUL9, Q8CGW0, Q8K2I6, Q8R0V7, Q8R130	Gene names	Ubr2, Kiaa0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

UBR2_HUMAN
NC score	0.978723 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	52	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IWV8, O15057, Q4VXK2, Q5TFH6, Q6P2I2, Q6ZUD0	Gene names	UBR2, C6orf133, KIAA0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

PP1R8_HUMAN
NC score	0.037880 (rank : 5)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	52	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q12972, Q5TIF2, Q6PKF6, Q9UBH1, Q9UBZ0	Gene names	PPP1R8, ARD1, NIPP1
Domain Architecture
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator of RNA decay (EC 3.1.4.-) (ARD-1)].

PP1R8_MOUSE
NC score	0.037857 (rank : 6)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	52	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R3G1, Q8C087	Gene names	Ppp1r8, Nipp1
Domain Architecture	No domain graphic available
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8).

EDD1_MOUSE
NC score	0.036877 (rank : 7)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	52	Target Neighborhood Hits	167	Shared Neighborhood Hits	7
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

EDD1_HUMAN
NC score	0.036873 (rank : 8)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	52	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

DYDC2_HUMAN
NC score	0.035486 (rank : 9)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	52	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q96IM9, Q5QP07, Q5QP11	Gene names	DYDC2
Domain Architecture	No domain graphic available
Description	DPY30 domain-containing protein 2.

STX1A_HUMAN
NC score	0.022611 (rank : 10)	θ value	0.0961366 (rank : 6)
Query Neighborhood Hits	52	Target Neighborhood Hits	266	Shared Neighborhood Hits	5
SwissProt Accessions	Q16623, O15447, O15448, Q12936, Q9BPZ6	Gene names	STX1A, STX1
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

MD2L1_MOUSE
NC score	0.020639 (rank : 11)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	52	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1B5, Q9JI53	Gene names	Mad2l1, Mad2a
Domain Architecture
Description	Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1).

FANCL_HUMAN
NC score	0.018990 (rank : 12)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	52	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NW38	Gene names	FANCL, PHF9
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein FANCL (EC 6.3.2.-) (Fanconi anemia group L protein) (Fanconi anemia-associated polypeptide of 43 kDa) (FAAP43).

UBP34_MOUSE
NC score	0.016558 (rank : 13)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	52	Target Neighborhood Hits	189	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

RYR3_HUMAN
NC score	0.016491 (rank : 14)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	52	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

JAK2_HUMAN
NC score	0.014987 (rank : 15)	θ value	0.0736092 (rank : 5)
Query Neighborhood Hits	52	Target Neighborhood Hits	847	Shared Neighborhood Hits	7
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

IFNK_HUMAN
NC score	0.014919 (rank : 16)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	52	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0W0, Q5T166	Gene names	IFNK
Domain Architecture	No domain graphic available
Description	Interferon kappa precursor (IFN-kappa).

TSNA1_HUMAN
NC score	0.014679 (rank : 17)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	52	Target Neighborhood Hits	178	Shared Neighborhood Hits	5
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

COPA_HUMAN
NC score	0.013803 (rank : 18)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	52	Target Neighborhood Hits	297	Shared Neighborhood Hits	3
SwissProt Accessions	P53621	Gene names	COPA
Domain Architecture
Description	Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEPCOP) (HEP- COP) [Contains: Xenin (Xenopsin-related peptide); Proxenin].

JAK2_MOUSE
NC score	0.013769 (rank : 19)	θ value	0.21417 (rank : 7)
Query Neighborhood Hits	52	Target Neighborhood Hits	839	Shared Neighborhood Hits	7
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

P66B_MOUSE
NC score	0.012502 (rank : 20)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	52	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHR5, Q8C9Q3	Gene names	Gatad2b
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger domain- containing protein 2B).

P66B_HUMAN
NC score	0.012491 (rank : 21)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	52	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXI9, Q7LG68, Q9ULS0	Gene names	GATAD2B, KIAA1150
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger domain- containing protein 2B).

IRX4_MOUSE
NC score	0.012150 (rank : 22)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	52	Target Neighborhood Hits	286	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QY61	Gene names	Irx4, Irxa3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein 4) (Homeodomain protein IRXA3).

NU153_HUMAN
NC score	0.011737 (rank : 23)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	52	Target Neighborhood Hits	227	Shared Neighborhood Hits	2
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

EDG4_MOUSE
NC score	0.011122 (rank : 24)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	52	Target Neighborhood Hits	461	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JL06	Gene names	Edg4, Lpa2
Domain Architecture
Description	Lysophosphatidic acid receptor Edg-4 (LPA receptor 2) (LPA-2).

IRX4_HUMAN
NC score	0.010456 (rank : 25)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	52	Target Neighborhood Hits	276	Shared Neighborhood Hits	3
SwissProt Accessions	P78413, Q9UHR2	Gene names	IRX4, IRXA3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein 4) (Homeodomain protein IRXA3).

TYRO_MOUSE
NC score	0.010337 (rank : 26)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	52	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P11344	Gene names	Tyr
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Albino locus protein).

ZN236_HUMAN
NC score	0.009666 (rank : 27)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	52	Target Neighborhood Hits	844	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UL36, Q9UL37	Gene names	ZNF236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 236.

ZN578_HUMAN
NC score	0.009380 (rank : 28)	θ value	0.365318 (rank : 8)
Query Neighborhood Hits	52	Target Neighborhood Hits	755	Shared Neighborhood Hits	17
SwissProt Accessions	Q96N58	Gene names	ZNF578
Domain Architecture	No domain graphic available
Description	Zinc finger protein 578.

ZN283_HUMAN
NC score	0.009231 (rank : 29)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	52	Target Neighborhood Hits	760	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N7M2	Gene names	ZNF283
Domain Architecture	No domain graphic available
Description	Zinc finger protein 283.

ZN583_MOUSE
NC score	0.009142 (rank : 30)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	52	Target Neighborhood Hits	774	Shared Neighborhood Hits	17
SwissProt Accessions	Q3V080, Q3V3L4	Gene names	Znf583, Zfp583
Domain Architecture	No domain graphic available
Description	Zinc finger protein 583.

RASF8_MOUSE
NC score	0.009038 (rank : 31)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	52	Target Neighborhood Hits	391	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CJ96, Q8CCW4, Q9CU91	Gene names	Rassf8
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1 homolog).

ZN583_HUMAN
NC score	0.008118 (rank : 32)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	52	Target Neighborhood Hits	774	Shared Neighborhood Hits	17
SwissProt Accessions	Q96ND8, O14850, Q2NKK3	Gene names	ZNF583
Domain Architecture	No domain graphic available
Description	Zinc finger protein 583 (Zinc finger protein L3-5).

DEST_MOUSE
NC score	0.008102 (rank : 33)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	52	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0P5	Gene names	Dstn, Dsn, Sid23
Domain Architecture
Description	Destrin (Actin-depolymerizing factor) (ADF) (Sid 23).

FARP1_HUMAN
NC score	0.008095 (rank : 34)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	52	Target Neighborhood Hits	241	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

ZN572_HUMAN
NC score	0.007797 (rank : 35)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	52	Target Neighborhood Hits	754	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z3I7, Q8N1Q0	Gene names	ZNF572
Domain Architecture	No domain graphic available
Description	Zinc finger protein 572.

ZN417_HUMAN
NC score	0.007509 (rank : 36)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	52	Target Neighborhood Hits	753	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TAU3	Gene names	ZNF417
Domain Architecture	No domain graphic available
Description	Zinc finger protein 417.

ZN587_HUMAN
NC score	0.007244 (rank : 37)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	52	Target Neighborhood Hits	756	Shared Neighborhood Hits	16
SwissProt Accessions	Q96SQ5, Q6ZMK8	Gene names	ZNF587
Domain Architecture	No domain graphic available
Description	Zinc finger protein 587.

HKR1_HUMAN
NC score	0.007053 (rank : 38)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	52	Target Neighborhood Hits	759	Shared Neighborhood Hits	17
SwissProt Accessions	P10072, Q9BSW9, Q9UM09	Gene names	HKR1
Domain Architecture
Description	Krueppel-related zinc finger protein 1 (Protein HKR1).

ZNF30_HUMAN
NC score	0.006795 (rank : 39)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	52	Target Neighborhood Hits	750	Shared Neighborhood Hits	16
SwissProt Accessions	P17039, Q6N068	Gene names	ZNF30, KOX28
Domain Architecture	No domain graphic available
Description	Zinc finger protein 30 (Zinc finger protein KOX28).

ZN527_HUMAN
NC score	0.006720 (rank : 40)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	52	Target Neighborhood Hits	751	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NB42	Gene names	ZNF527
Domain Architecture	No domain graphic available
Description	Zinc finger protein 527.

ZNF91_HUMAN
NC score	0.006678 (rank : 41)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	52	Target Neighborhood Hits	797	Shared Neighborhood Hits	16
SwissProt Accessions	Q05481	Gene names	ZNF91
Domain Architecture
Description	Zinc finger protein 91 (Zinc finger protein HTF10) (HPF7).

SYNE1_HUMAN
NC score	0.006657 (rank : 42)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	52	Target Neighborhood Hits	1484	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

ZN546_HUMAN
NC score	0.006655 (rank : 43)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	52	Target Neighborhood Hits	772	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UE3	Gene names	ZNF546, ZNF49
Domain Architecture	No domain graphic available
Description	Zinc finger protein 546.

ZN345_HUMAN
NC score	0.006608 (rank : 44)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	52	Target Neighborhood Hits	748	Shared Neighborhood Hits	16
SwissProt Accessions	Q14585	Gene names	ZNF345
Domain Architecture	No domain graphic available
Description	Zinc finger protein 345 (Zinc finger protein HZF10).

SP8_HUMAN
NC score	0.006226 (rank : 45)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	52	Target Neighborhood Hits	714	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IXZ3, Q7Z616, Q96MJ1	Gene names	SP8
Domain Architecture	No domain graphic available
Description	Transcription factor Sp8 (Specificity protein 8).

ZFY16_MOUSE
NC score	0.006114 (rank : 46)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	52	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	Q80U44, Q8BRD2, Q8CG97	Gene names	Zfyve16, Kiaa0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosomal- associated FYVE domain protein).

PTN2_HUMAN
NC score	0.005989 (rank : 47)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	52	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

TAXB1_MOUSE
NC score	0.004426 (rank : 48)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	52	Target Neighborhood Hits	886	Shared Neighborhood Hits	7
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

LMNB2_MOUSE
NC score	0.003773 (rank : 49)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	52	Target Neighborhood Hits	674	Shared Neighborhood Hits	5
SwissProt Accessions	P21619, P48680, Q8CGB1	Gene names	Lmnb2
Domain Architecture
Description	Lamin-B2.

DCAK2_MOUSE
NC score	0.002599 (rank : 50)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	52	Target Neighborhood Hits	858	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PGN3, Q8BUU0, Q8BX25	Gene names	Dcamkl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 2).

DCAK2_HUMAN
NC score	0.002597 (rank : 51)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	52	Target Neighborhood Hits	862	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N568, Q8N399	Gene names	DCAMKL2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 2).

TITIN_HUMAN
NC score	0.001544 (rank : 52)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	52	Target Neighborhood Hits	2923	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).