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Network neighborhood for query Sequence : TPP1_MOUSE

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TPP1_MOUSE
SwissProt Accessions	O89023, Q543Q8, Q9QUS7	Gene names	Tpp1, Cln2
Domain Architecture
Description	Tripeptidyl-peptidase 1 precursor (EC 3.4.14.9) (Tripeptidyl-peptidase I) (TPP-I) (Tripeptidyl aminopeptidase) (Lysosomal pepstatin insensitive protease) (LPIC).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TPP1_HUMAN
θ value	0 (rank : 1)	NC score	0.994719 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	O14773, Q53HT1, Q5JAK6, Q6UX56, Q96C37	Gene names	TPP1, CLN2, GIG1
Domain Architecture
Description	Tripeptidyl-peptidase 1 precursor (EC 3.4.14.9) (Tripeptidyl-peptidase I) (TPP-I) (Tripeptidyl aminopeptidase) (Lysosomal pepstatin insensitive protease) (LPIC) (Growth-inhibiting gene 1 protein).

TPP1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	O89023, Q543Q8, Q9QUS7	Gene names	Tpp1, Cln2
Domain Architecture
Description	Tripeptidyl-peptidase 1 precursor (EC 3.4.14.9) (Tripeptidyl-peptidase I) (TPP-I) (Tripeptidyl aminopeptidase) (Lysosomal pepstatin insensitive protease) (LPIC).

COG7_HUMAN
θ value	0.21417 (rank : 3)	NC score	0.096270 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	P83436, Q6UWU7	Gene names	COG7
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 7.

UDB7_HUMAN
θ value	0.279714 (rank : 4)	NC score	0.073549 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	P16662	Gene names	UGT2B7, UGTB2B9
Domain Architecture
Description	UDP-glucuronosyltransferase 2B7 precursor (EC 2.4.1.17) (UDPGT) (3,4- catechol estrogen specific) (UDPGTh-2).

UDB28_HUMAN
θ value	0.813845 (rank : 5)	NC score	0.068380 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BY64, Q9BY62, Q9BY63	Gene names	UGT2B28
Domain Architecture
Description	UDP-glucuronosyltransferase 2B28 precursor (EC 2.4.1.17) (UDPGT).

PAX8_HUMAN
θ value	1.06291 (rank : 6)	NC score	0.031618 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q06710, Q09155, Q16337, Q16338, Q16339, Q96J49	Gene names	PAX8
Domain Architecture
Description	Paired box protein Pax-8.

PAX8_MOUSE
θ value	1.06291 (rank : 7)	NC score	0.031552 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q00288, P97342	Gene names	Pax8, Pax-8
Domain Architecture
Description	Paired box protein Pax-8.

CK5P3_MOUSE
θ value	1.38821 (rank : 8)	NC score	0.040944 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LM2, Q3UE41	Gene names	Cdk5rap3
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 3.

UDB15_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.066969 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	P54855, P23765, Q9UK63	Gene names	UGT2B15, UGT2B8
Domain Architecture
Description	UDP-glucuronosyltransferase 2B15 precursor (EC 2.4.1.17) (UDPGT) (UDPGTh-3) (HLUG4).

UDB17_HUMAN
θ value	1.38821 (rank : 10)	NC score	0.066750 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	O75795	Gene names	UGT2B17
Domain Architecture
Description	UDP-glucuronosyltransferase 2B17 precursor (EC 2.4.1.17) (UDPGT) (C19- steroid-specific UDP-glucuronosyltransferase).

UDB4_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.064476 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	P06133, O60731, O60867, O75614, P36538	Gene names	UGT2B4, UGT2B11
Domain Architecture
Description	UDP-glucuronosyltransferase 2B4 precursor (EC 2.4.1.17) (UDPGT) (Hyodeoxycholic acid) (HLUG25) (UDPGTh-1).

UDB11_HUMAN
θ value	1.81305 (rank : 12)	NC score	0.064839 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	O75310, Q3KNV9	Gene names	UGT2B11
Domain Architecture
Description	UDP-glucuronosyltransferase 2B11 precursor (EC 2.4.1.17) (UDPGT).

PARP6_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.046830 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q2NL67, Q9H7C5, Q9H9X6, Q9HAF3, Q9NPS6, Q9UFG4	Gene names	PARP6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PARP6_MOUSE
θ value	3.0926 (rank : 14)	NC score	0.046823 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P6P7, Q8BVW1	Gene names	Parp6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

UDB10_HUMAN
θ value	4.03905 (rank : 15)	NC score	0.059200 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	P36537	Gene names	UGT2B10
Domain Architecture
Description	UDP-glucuronosyltransferase 2B10 precursor (EC 2.4.1.17) (UDPGT).

UDB5_MOUSE
θ value	4.03905 (rank : 16)	NC score	0.061534 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	P17717	Gene names	Ugt2b5
Domain Architecture
Description	UDP-glucuronosyltransferase 2B5 precursor (EC 2.4.1.17) (UDPGT) (M-1).

ZC3H6_MOUSE
θ value	4.03905 (rank : 17)	NC score	0.018136 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	239	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

MUCEN_MOUSE
θ value	6.88961 (rank : 18)	NC score	0.035537 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

RNF17_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.019544 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXT8, Q9BXT7	Gene names	RNF17
Domain Architecture
Description	RING finger protein 17.

ELK3_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.007332 (rank : 21)
Query Neighborhood Hits	20	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	P41971, P97747, Q62346	Gene names	Elk3, Erp, Net
Domain Architecture
Description	ETS domain-containing protein Elk-3 (ETS-related protein NET) (ETS- related protein ERP).

UDA1_HUMAN
θ value	θ > 10 (rank : 21)	NC score	0.052518 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4X1	Gene names	UGT2A1
Domain Architecture
Description	UDP-glucuronosyltransferase 2A1 precursor (EC 2.4.1.17).

Hits sorted by NC score

TPP1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	O89023, Q543Q8, Q9QUS7	Gene names	Tpp1, Cln2
Domain Architecture
Description	Tripeptidyl-peptidase 1 precursor (EC 3.4.14.9) (Tripeptidyl-peptidase I) (TPP-I) (Tripeptidyl aminopeptidase) (Lysosomal pepstatin insensitive protease) (LPIC).

TPP1_HUMAN
NC score	0.994719 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	O14773, Q53HT1, Q5JAK6, Q6UX56, Q96C37	Gene names	TPP1, CLN2, GIG1
Domain Architecture
Description	Tripeptidyl-peptidase 1 precursor (EC 3.4.14.9) (Tripeptidyl-peptidase I) (TPP-I) (Tripeptidyl aminopeptidase) (Lysosomal pepstatin insensitive protease) (LPIC) (Growth-inhibiting gene 1 protein).

COG7_HUMAN
NC score	0.096270 (rank : 3)	θ value	0.21417 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	P83436, Q6UWU7	Gene names	COG7
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 7.

UDB7_HUMAN
NC score	0.073549 (rank : 4)	θ value	0.279714 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	P16662	Gene names	UGT2B7, UGTB2B9
Domain Architecture
Description	UDP-glucuronosyltransferase 2B7 precursor (EC 2.4.1.17) (UDPGT) (3,4- catechol estrogen specific) (UDPGTh-2).

UDB28_HUMAN
NC score	0.068380 (rank : 5)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BY64, Q9BY62, Q9BY63	Gene names	UGT2B28
Domain Architecture
Description	UDP-glucuronosyltransferase 2B28 precursor (EC 2.4.1.17) (UDPGT).

UDB15_HUMAN
NC score	0.066969 (rank : 6)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	P54855, P23765, Q9UK63	Gene names	UGT2B15, UGT2B8
Domain Architecture
Description	UDP-glucuronosyltransferase 2B15 precursor (EC 2.4.1.17) (UDPGT) (UDPGTh-3) (HLUG4).

UDB17_HUMAN
NC score	0.066750 (rank : 7)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	O75795	Gene names	UGT2B17
Domain Architecture
Description	UDP-glucuronosyltransferase 2B17 precursor (EC 2.4.1.17) (UDPGT) (C19- steroid-specific UDP-glucuronosyltransferase).

UDB11_HUMAN
NC score	0.064839 (rank : 8)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	O75310, Q3KNV9	Gene names	UGT2B11
Domain Architecture
Description	UDP-glucuronosyltransferase 2B11 precursor (EC 2.4.1.17) (UDPGT).

UDB4_HUMAN
NC score	0.064476 (rank : 9)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	P06133, O60731, O60867, O75614, P36538	Gene names	UGT2B4, UGT2B11
Domain Architecture
Description	UDP-glucuronosyltransferase 2B4 precursor (EC 2.4.1.17) (UDPGT) (Hyodeoxycholic acid) (HLUG25) (UDPGTh-1).

UDB5_MOUSE
NC score	0.061534 (rank : 10)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	P17717	Gene names	Ugt2b5
Domain Architecture
Description	UDP-glucuronosyltransferase 2B5 precursor (EC 2.4.1.17) (UDPGT) (M-1).

UDB10_HUMAN
NC score	0.059200 (rank : 11)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	P36537	Gene names	UGT2B10
Domain Architecture
Description	UDP-glucuronosyltransferase 2B10 precursor (EC 2.4.1.17) (UDPGT).

UDA1_HUMAN
NC score	0.052518 (rank : 12)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	20	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4X1	Gene names	UGT2A1
Domain Architecture
Description	UDP-glucuronosyltransferase 2A1 precursor (EC 2.4.1.17).

PARP6_HUMAN
NC score	0.046830 (rank : 13)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q2NL67, Q9H7C5, Q9H9X6, Q9HAF3, Q9NPS6, Q9UFG4	Gene names	PARP6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PARP6_MOUSE
NC score	0.046823 (rank : 14)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P6P7, Q8BVW1	Gene names	Parp6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

CK5P3_MOUSE
NC score	0.040944 (rank : 15)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LM2, Q3UE41	Gene names	Cdk5rap3
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 3.

MUCEN_MOUSE
NC score	0.035537 (rank : 16)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

PAX8_HUMAN
NC score	0.031618 (rank : 17)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q06710, Q09155, Q16337, Q16338, Q16339, Q96J49	Gene names	PAX8
Domain Architecture
Description	Paired box protein Pax-8.

PAX8_MOUSE
NC score	0.031552 (rank : 18)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q00288, P97342	Gene names	Pax8, Pax-8
Domain Architecture
Description	Paired box protein Pax-8.

RNF17_HUMAN
NC score	0.019544 (rank : 19)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXT8, Q9BXT7	Gene names	RNF17
Domain Architecture
Description	RING finger protein 17.

ZC3H6_MOUSE
NC score	0.018136 (rank : 20)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	239	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ELK3_MOUSE
NC score	0.007332 (rank : 21)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	P41971, P97747, Q62346	Gene names	Elk3, Erp, Net
Domain Architecture
Description	ETS domain-containing protein Elk-3 (ETS-related protein NET) (ETS- related protein ERP).