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Network neighborhood for query Sequence : TPP1_HUMAN

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TPP1_HUMAN
SwissProt Accessions	O14773, Q53HT1, Q5JAK6, Q6UX56, Q96C37	Gene names	TPP1, CLN2, GIG1
Domain Architecture
Description	Tripeptidyl-peptidase 1 precursor (EC 3.4.14.9) (Tripeptidyl-peptidase I) (TPP-I) (Tripeptidyl aminopeptidase) (Lysosomal pepstatin insensitive protease) (LPIC) (Growth-inhibiting gene 1 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TPP1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	O14773, Q53HT1, Q5JAK6, Q6UX56, Q96C37	Gene names	TPP1, CLN2, GIG1
Domain Architecture
Description	Tripeptidyl-peptidase 1 precursor (EC 3.4.14.9) (Tripeptidyl-peptidase I) (TPP-I) (Tripeptidyl aminopeptidase) (Lysosomal pepstatin insensitive protease) (LPIC) (Growth-inhibiting gene 1 protein).

TPP1_MOUSE
θ value	0 (rank : 2)	NC score	0.994719 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	O89023, Q543Q8, Q9QUS7	Gene names	Tpp1, Cln2
Domain Architecture
Description	Tripeptidyl-peptidase 1 precursor (EC 3.4.14.9) (Tripeptidyl-peptidase I) (TPP-I) (Tripeptidyl aminopeptidase) (Lysosomal pepstatin insensitive protease) (LPIC).

CO6A1_HUMAN
θ value	0.0961366 (rank : 3)	NC score	0.035657 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	264	Shared Neighborhood Hits	3
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

UDB7_HUMAN
θ value	0.163984 (rank : 4)	NC score	0.079821 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	P16662	Gene names	UGT2B7, UGTB2B9
Domain Architecture
Description	UDP-glucuronosyltransferase 2B7 precursor (EC 2.4.1.17) (UDPGT) (3,4- catechol estrogen specific) (UDPGTh-2).

CO6A1_MOUSE
θ value	0.62314 (rank : 5)	NC score	0.034086 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	241	Shared Neighborhood Hits	4
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

UDB15_HUMAN
θ value	0.62314 (rank : 6)	NC score	0.073454 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	P54855, P23765, Q9UK63	Gene names	UGT2B15, UGT2B8
Domain Architecture
Description	UDP-glucuronosyltransferase 2B15 precursor (EC 2.4.1.17) (UDPGT) (UDPGTh-3) (HLUG4).

UDB17_HUMAN
θ value	0.62314 (rank : 7)	NC score	0.073236 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	O75795	Gene names	UGT2B17
Domain Architecture
Description	UDP-glucuronosyltransferase 2B17 precursor (EC 2.4.1.17) (UDPGT) (C19- steroid-specific UDP-glucuronosyltransferase).

UDB28_HUMAN
θ value	0.813845 (rank : 8)	NC score	0.074517 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BY64, Q9BY62, Q9BY63	Gene names	UGT2B28
Domain Architecture
Description	UDP-glucuronosyltransferase 2B28 precursor (EC 2.4.1.17) (UDPGT).

SC24C_HUMAN
θ value	1.06291 (rank : 9)	NC score	0.025026 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	662	Shared Neighborhood Hits	2
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

PARP6_HUMAN
θ value	1.81305 (rank : 10)	NC score	0.051968 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q2NL67, Q9H7C5, Q9H9X6, Q9HAF3, Q9NPS6, Q9UFG4	Gene names	PARP6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PARP6_MOUSE
θ value	1.81305 (rank : 11)	NC score	0.051960 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P6P7, Q8BVW1	Gene names	Parp6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

UDB11_HUMAN
θ value	1.81305 (rank : 12)	NC score	0.070995 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	O75310, Q3KNV9	Gene names	UGT2B11
Domain Architecture
Description	UDP-glucuronosyltransferase 2B11 precursor (EC 2.4.1.17) (UDPGT).

UDB5_MOUSE
θ value	1.81305 (rank : 13)	NC score	0.068137 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	P17717	Gene names	Ugt2b5
Domain Architecture
Description	UDP-glucuronosyltransferase 2B5 precursor (EC 2.4.1.17) (UDPGT) (M-1).

COG7_HUMAN
θ value	2.36792 (rank : 14)	NC score	0.076915 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	P83436, Q6UWU7	Gene names	COG7
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 7.

UDB4_HUMAN
θ value	2.36792 (rank : 15)	NC score	0.070652 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	P06133, O60731, O60867, O75614, P36538	Gene names	UGT2B4, UGT2B11
Domain Architecture
Description	UDP-glucuronosyltransferase 2B4 precursor (EC 2.4.1.17) (UDPGT) (Hyodeoxycholic acid) (HLUG25) (UDPGTh-1).

B4GN4_MOUSE
θ value	4.03905 (rank : 16)	NC score	0.017998 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	129	Shared Neighborhood Hits	2
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

UDA1_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.059435 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y4X1	Gene names	UGT2A1
Domain Architecture
Description	UDP-glucuronosyltransferase 2A1 precursor (EC 2.4.1.17).

APXL_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.015020 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	553	Shared Neighborhood Hits	3
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

TSSC4_MOUSE
θ value	6.88961 (rank : 19)	NC score	0.023538 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHE7	Gene names	Tssc4
Domain Architecture	No domain graphic available
Description	Protein TSSC4.

ADA2B_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.001461 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	891	Shared Neighborhood Hits	2
SwissProt Accessions	P30545	Gene names	Adra2b
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor).

FA43B_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.016483 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZT52	Gene names	FAM43B
Domain Architecture	No domain graphic available
Description	Protein FAM43B.

MUCEN_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.033479 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

UDB10_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.065233 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	P36537	Gene names	UGT2B10
Domain Architecture
Description	UDP-glucuronosyltransferase 2B10 precursor (EC 2.4.1.17) (UDPGT).

Hits sorted by NC score

TPP1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	O14773, Q53HT1, Q5JAK6, Q6UX56, Q96C37	Gene names	TPP1, CLN2, GIG1
Domain Architecture
Description	Tripeptidyl-peptidase 1 precursor (EC 3.4.14.9) (Tripeptidyl-peptidase I) (TPP-I) (Tripeptidyl aminopeptidase) (Lysosomal pepstatin insensitive protease) (LPIC) (Growth-inhibiting gene 1 protein).

TPP1_MOUSE
NC score	0.994719 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	O89023, Q543Q8, Q9QUS7	Gene names	Tpp1, Cln2
Domain Architecture
Description	Tripeptidyl-peptidase 1 precursor (EC 3.4.14.9) (Tripeptidyl-peptidase I) (TPP-I) (Tripeptidyl aminopeptidase) (Lysosomal pepstatin insensitive protease) (LPIC).

UDB7_HUMAN
NC score	0.079821 (rank : 3)	θ value	0.163984 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	P16662	Gene names	UGT2B7, UGTB2B9
Domain Architecture
Description	UDP-glucuronosyltransferase 2B7 precursor (EC 2.4.1.17) (UDPGT) (3,4- catechol estrogen specific) (UDPGTh-2).

COG7_HUMAN
NC score	0.076915 (rank : 4)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	P83436, Q6UWU7	Gene names	COG7
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 7.

UDB28_HUMAN
NC score	0.074517 (rank : 5)	θ value	0.813845 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BY64, Q9BY62, Q9BY63	Gene names	UGT2B28
Domain Architecture
Description	UDP-glucuronosyltransferase 2B28 precursor (EC 2.4.1.17) (UDPGT).

UDB15_HUMAN
NC score	0.073454 (rank : 6)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	P54855, P23765, Q9UK63	Gene names	UGT2B15, UGT2B8
Domain Architecture
Description	UDP-glucuronosyltransferase 2B15 precursor (EC 2.4.1.17) (UDPGT) (UDPGTh-3) (HLUG4).

UDB17_HUMAN
NC score	0.073236 (rank : 7)	θ value	0.62314 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	O75795	Gene names	UGT2B17
Domain Architecture
Description	UDP-glucuronosyltransferase 2B17 precursor (EC 2.4.1.17) (UDPGT) (C19- steroid-specific UDP-glucuronosyltransferase).

UDB11_HUMAN
NC score	0.070995 (rank : 8)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	O75310, Q3KNV9	Gene names	UGT2B11
Domain Architecture
Description	UDP-glucuronosyltransferase 2B11 precursor (EC 2.4.1.17) (UDPGT).

UDB4_HUMAN
NC score	0.070652 (rank : 9)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	P06133, O60731, O60867, O75614, P36538	Gene names	UGT2B4, UGT2B11
Domain Architecture
Description	UDP-glucuronosyltransferase 2B4 precursor (EC 2.4.1.17) (UDPGT) (Hyodeoxycholic acid) (HLUG25) (UDPGTh-1).

UDB5_MOUSE
NC score	0.068137 (rank : 10)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	P17717	Gene names	Ugt2b5
Domain Architecture
Description	UDP-glucuronosyltransferase 2B5 precursor (EC 2.4.1.17) (UDPGT) (M-1).

UDB10_HUMAN
NC score	0.065233 (rank : 11)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	P36537	Gene names	UGT2B10
Domain Architecture
Description	UDP-glucuronosyltransferase 2B10 precursor (EC 2.4.1.17) (UDPGT).

UDA1_HUMAN
NC score	0.059435 (rank : 12)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y4X1	Gene names	UGT2A1
Domain Architecture
Description	UDP-glucuronosyltransferase 2A1 precursor (EC 2.4.1.17).

PARP6_HUMAN
NC score	0.051968 (rank : 13)	θ value	1.81305 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q2NL67, Q9H7C5, Q9H9X6, Q9HAF3, Q9NPS6, Q9UFG4	Gene names	PARP6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PARP6_MOUSE
NC score	0.051960 (rank : 14)	θ value	1.81305 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P6P7, Q8BVW1	Gene names	Parp6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

CO6A1_HUMAN
NC score	0.035657 (rank : 15)	θ value	0.0961366 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	264	Shared Neighborhood Hits	3
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO6A1_MOUSE
NC score	0.034086 (rank : 16)	θ value	0.62314 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	241	Shared Neighborhood Hits	4
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

MUCEN_MOUSE
NC score	0.033479 (rank : 17)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0H2, Q78KL2, Q9DCN9, Q9ULC1, Q9Z2I1	Gene names	Emcn, Muc14
Domain Architecture	No domain graphic available
Description	Endomucin precursor (Endomucin-1/2).

SC24C_HUMAN
NC score	0.025026 (rank : 18)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	662	Shared Neighborhood Hits	2
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

TSSC4_MOUSE
NC score	0.023538 (rank : 19)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHE7	Gene names	Tssc4
Domain Architecture	No domain graphic available
Description	Protein TSSC4.

B4GN4_MOUSE
NC score	0.017998 (rank : 20)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	129	Shared Neighborhood Hits	2
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

FA43B_HUMAN
NC score	0.016483 (rank : 21)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZT52	Gene names	FAM43B
Domain Architecture	No domain graphic available
Description	Protein FAM43B.

APXL_HUMAN
NC score	0.015020 (rank : 22)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	553	Shared Neighborhood Hits	3
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

ADA2B_MOUSE
NC score	0.001461 (rank : 23)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	891	Shared Neighborhood Hits	2
SwissProt Accessions	P30545	Gene names	Adra2b
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor).