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Network neighborhood for query Sequence : TFF1_HUMAN

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TFF1_HUMAN
SwissProt Accessions	P04155	Gene names	TFF1, BCEI, PS2
Domain Architecture
Description	Trefoil factor 1 precursor (pS2 protein) (HP1.A) (Breast cancer estrogen-inducible protein) (PNR-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TFF1_HUMAN
θ value	2.85459e-46 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	P04155	Gene names	TFF1, BCEI, PS2
Domain Architecture
Description	Trefoil factor 1 precursor (pS2 protein) (HP1.A) (Breast cancer estrogen-inducible protein) (PNR-2).

TFF1_MOUSE
θ value	1.92365e-26 (rank : 2)	NC score	0.980556 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	Q08423, Q3TVE6	Gene names	Tff1, Bcei, Ps2
Domain Architecture
Description	Trefoil factor 1 precursor (pS2 protein).

TFF2_HUMAN
θ value	4.16044e-13 (rank : 3)	NC score	0.820340 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q03403, Q15854	Gene names	TFF2, SML1
Domain Architecture
Description	Trefoil factor 2 precursor (Spasmolytic polypeptide) (SP) (Spasmolysin).

TFF3_HUMAN
θ value	2.0648e-12 (rank : 4)	NC score	0.885082 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	Q07654	Gene names	TFF3, ITF, TFI
Domain Architecture
Description	Trefoil factor 3 precursor (Intestinal trefoil factor) (hP1.B).

TFF2_MOUSE
θ value	3.52202e-12 (rank : 5)	NC score	0.819130 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q03404, O08913	Gene names	Tff2, Sml1, Sp
Domain Architecture
Description	Trefoil factor 2 precursor (Spasmolytic polypeptide) (SP).

TFF3_MOUSE
θ value	5.62301e-10 (rank : 6)	NC score	0.862486 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q62395, Q64352	Gene names	Tff3, Itf
Domain Architecture
Description	Trefoil factor 3 precursor (Intestinal trefoil factor).

LYAG_MOUSE
θ value	0.0148317 (rank : 7)	NC score	0.195523 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	P70699, Q3UJB2, Q8BGI6, Q91Z45	Gene names	Gaa
Domain Architecture
Description	Lysosomal alpha-glucosidase precursor (EC 3.2.1.20) (Acid maltase).

LYAG_HUMAN
θ value	0.0193708 (rank : 8)	NC score	0.196171 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	24	Shared Neighborhood Hits	10
SwissProt Accessions	P10253, Q14351, Q16302	Gene names	GAA
Domain Architecture
Description	Lysosomal alpha-glucosidase precursor (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Contains: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase].

MGA_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.104072 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	30	Shared Neighborhood Hits	7
SwissProt Accessions	O43451	Gene names	MGAM, MGA, MGAML
Domain Architecture
Description	Maltase-glucoamylase, intestinal [Includes: Maltase (EC 3.2.1.20) (Alpha-glucosidase); Glucoamylase (EC 3.2.1.3) (Glucan 1,4-alpha- glucosidase)].

ZP4_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.044459 (rank : 15)
Query Neighborhood Hits	11	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q12836	Gene names	ZP4, ZPB
Domain Architecture
Description	Zona pellucida sperm-binding protein 4 precursor (Zona pellucida sperm-binding protein B).

GANAB_HUMAN
θ value	θ > 10 (rank : 12)	NC score	0.065190 (rank : 14)
Query Neighborhood Hits	11	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q14697, Q8WTS9, Q9P0X0	Gene names	GANAB, G2AN, KIAA0088
Domain Architecture
Description	Neutral alpha-glucosidase AB precursor (EC 3.2.1.84) (Glucosidase II subunit alpha).

GANAB_MOUSE
θ value	θ > 10 (rank : 13)	NC score	0.065607 (rank : 13)
Query Neighborhood Hits	11	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHN3, O08794, Q80U81, Q9CS53	Gene names	Ganab, G2an, Kiaa0088
Domain Architecture
Description	Neutral alpha-glucosidase AB precursor (EC 3.2.1.84) (Glucosidase II subunit alpha) (Alpha glucosidase 2).

GANC_HUMAN
θ value	θ > 10 (rank : 14)	NC score	0.065630 (rank : 12)
Query Neighborhood Hits	11	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TET4, Q52LQ4, Q8IWZ0, Q8IZM4, Q8IZM5	Gene names	GANC
Domain Architecture
Description	Neutral alpha-glucosidase C (EC 3.2.1.20).

GANC_MOUSE
θ value	θ > 10 (rank : 15)	NC score	0.066476 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVW0, Q8BH03	Gene names	Ganc
Domain Architecture
Description	Neutral alpha-glucosidase C (EC 3.2.1.-).

SUIS_HUMAN
θ value	θ > 10 (rank : 16)	NC score	0.092295 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	P14410	Gene names	SI
Domain Architecture
Description	Sucrase-isomaltase, intestinal [Contains: Sucrase (EC 3.2.1.48); Isomaltase (EC 3.2.1.10)].

Hits sorted by NC score

TFF1_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.85459e-46 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	P04155	Gene names	TFF1, BCEI, PS2
Domain Architecture
Description	Trefoil factor 1 precursor (pS2 protein) (HP1.A) (Breast cancer estrogen-inducible protein) (PNR-2).

TFF1_MOUSE
NC score	0.980556 (rank : 2)	θ value	1.92365e-26 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	Q08423, Q3TVE6	Gene names	Tff1, Bcei, Ps2
Domain Architecture
Description	Trefoil factor 1 precursor (pS2 protein).

TFF3_HUMAN
NC score	0.885082 (rank : 3)	θ value	2.0648e-12 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	Q07654	Gene names	TFF3, ITF, TFI
Domain Architecture
Description	Trefoil factor 3 precursor (Intestinal trefoil factor) (hP1.B).

TFF3_MOUSE
NC score	0.862486 (rank : 4)	θ value	5.62301e-10 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	Q62395, Q64352	Gene names	Tff3, Itf
Domain Architecture
Description	Trefoil factor 3 precursor (Intestinal trefoil factor).

TFF2_HUMAN
NC score	0.820340 (rank : 5)	θ value	4.16044e-13 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q03403, Q15854	Gene names	TFF2, SML1
Domain Architecture
Description	Trefoil factor 2 precursor (Spasmolytic polypeptide) (SP) (Spasmolysin).

TFF2_MOUSE
NC score	0.819130 (rank : 6)	θ value	3.52202e-12 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q03404, O08913	Gene names	Tff2, Sml1, Sp
Domain Architecture
Description	Trefoil factor 2 precursor (Spasmolytic polypeptide) (SP).

LYAG_HUMAN
NC score	0.196171 (rank : 7)	θ value	0.0193708 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	24	Shared Neighborhood Hits	10
SwissProt Accessions	P10253, Q14351, Q16302	Gene names	GAA
Domain Architecture
Description	Lysosomal alpha-glucosidase precursor (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Contains: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase].

LYAG_MOUSE
NC score	0.195523 (rank : 8)	θ value	0.0148317 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	P70699, Q3UJB2, Q8BGI6, Q91Z45	Gene names	Gaa
Domain Architecture
Description	Lysosomal alpha-glucosidase precursor (EC 3.2.1.20) (Acid maltase).

MGA_HUMAN
NC score	0.104072 (rank : 9)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	30	Shared Neighborhood Hits	7
SwissProt Accessions	O43451	Gene names	MGAM, MGA, MGAML
Domain Architecture
Description	Maltase-glucoamylase, intestinal [Includes: Maltase (EC 3.2.1.20) (Alpha-glucosidase); Glucoamylase (EC 3.2.1.3) (Glucan 1,4-alpha- glucosidase)].

SUIS_HUMAN
NC score	0.092295 (rank : 10)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	11	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	P14410	Gene names	SI
Domain Architecture
Description	Sucrase-isomaltase, intestinal [Contains: Sucrase (EC 3.2.1.48); Isomaltase (EC 3.2.1.10)].

GANC_MOUSE
NC score	0.066476 (rank : 11)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVW0, Q8BH03	Gene names	Ganc
Domain Architecture
Description	Neutral alpha-glucosidase C (EC 3.2.1.-).

GANC_HUMAN
NC score	0.065630 (rank : 12)	θ value	θ > 10 (rank : 14)
Query Neighborhood Hits	11	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TET4, Q52LQ4, Q8IWZ0, Q8IZM4, Q8IZM5	Gene names	GANC
Domain Architecture
Description	Neutral alpha-glucosidase C (EC 3.2.1.20).

GANAB_MOUSE
NC score	0.065607 (rank : 13)	θ value	θ > 10 (rank : 13)
Query Neighborhood Hits	11	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHN3, O08794, Q80U81, Q9CS53	Gene names	Ganab, G2an, Kiaa0088
Domain Architecture
Description	Neutral alpha-glucosidase AB precursor (EC 3.2.1.84) (Glucosidase II subunit alpha) (Alpha glucosidase 2).

GANAB_HUMAN
NC score	0.065190 (rank : 14)	θ value	θ > 10 (rank : 12)
Query Neighborhood Hits	11	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q14697, Q8WTS9, Q9P0X0	Gene names	GANAB, G2AN, KIAA0088
Domain Architecture
Description	Neutral alpha-glucosidase AB precursor (EC 3.2.1.84) (Glucosidase II subunit alpha).

ZP4_HUMAN
NC score	0.044459 (rank : 15)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q12836	Gene names	ZP4, ZPB
Domain Architecture
Description	Zona pellucida sperm-binding protein 4 precursor (Zona pellucida sperm-binding protein B).