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Network neighborhood for query Sequence : LYAG_MOUSE

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LYAG_MOUSE
SwissProt Accessions	P70699, Q3UJB2, Q8BGI6, Q91Z45	Gene names	Gaa
Domain Architecture
Description	Lysosomal alpha-glucosidase precursor (EC 3.2.1.20) (Acid maltase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LYAG_HUMAN
θ value	0 (rank : 1)	NC score	0.997908 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	15
SwissProt Accessions	P10253, Q14351, Q16302	Gene names	GAA
Domain Architecture
Description	Lysosomal alpha-glucosidase precursor (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Contains: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase].

LYAG_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	P70699, Q3UJB2, Q8BGI6, Q91Z45	Gene names	Gaa
Domain Architecture
Description	Lysosomal alpha-glucosidase precursor (EC 3.2.1.20) (Acid maltase).

MGA_HUMAN
θ value	0 (rank : 3)	NC score	0.961113 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	O43451	Gene names	MGAM, MGA, MGAML
Domain Architecture
Description	Maltase-glucoamylase, intestinal [Includes: Maltase (EC 3.2.1.20) (Alpha-glucosidase); Glucoamylase (EC 3.2.1.3) (Glucan 1,4-alpha- glucosidase)].

SUIS_HUMAN
θ value	0 (rank : 4)	NC score	0.961107 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	P14410	Gene names	SI
Domain Architecture
Description	Sucrase-isomaltase, intestinal [Contains: Sucrase (EC 3.2.1.48); Isomaltase (EC 3.2.1.10)].

GANC_MOUSE
θ value	1.54472e-92 (rank : 5)	NC score	0.905306 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BVW0, Q8BH03	Gene names	Ganc
Domain Architecture
Description	Neutral alpha-glucosidase C (EC 3.2.1.-).

GANAB_MOUSE
θ value	1.70789e-91 (rank : 6)	NC score	0.899157 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BHN3, O08794, Q80U81, Q9CS53	Gene names	Ganab, G2an, Kiaa0088
Domain Architecture
Description	Neutral alpha-glucosidase AB precursor (EC 3.2.1.84) (Glucosidase II subunit alpha) (Alpha glucosidase 2).

GANC_HUMAN
θ value	7.17548e-90 (rank : 7)	NC score	0.902986 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TET4, Q52LQ4, Q8IWZ0, Q8IZM4, Q8IZM5	Gene names	GANC
Domain Architecture
Description	Neutral alpha-glucosidase C (EC 3.2.1.20).

GANAB_HUMAN
θ value	5.14231e-88 (rank : 8)	NC score	0.899057 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q14697, Q8WTS9, Q9P0X0	Gene names	GANAB, G2AN, KIAA0088
Domain Architecture
Description	Neutral alpha-glucosidase AB precursor (EC 3.2.1.84) (Glucosidase II subunit alpha).

TFF3_MOUSE
θ value	0.00175202 (rank : 9)	NC score	0.229763 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q62395, Q64352	Gene names	Tff3, Itf
Domain Architecture
Description	Trefoil factor 3 precursor (Intestinal trefoil factor).

TFF2_HUMAN
θ value	0.00390308 (rank : 10)	NC score	0.178581 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q03403, Q15854	Gene names	TFF2, SML1
Domain Architecture
Description	Trefoil factor 2 precursor (Spasmolytic polypeptide) (SP) (Spasmolysin).

TFF2_MOUSE
θ value	0.00665767 (rank : 11)	NC score	0.163680 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q03404, O08913	Gene names	Tff2, Sml1, Sp
Domain Architecture
Description	Trefoil factor 2 precursor (Spasmolytic polypeptide) (SP).

TFF1_HUMAN
θ value	0.0148317 (rank : 12)	NC score	0.195523 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	P04155	Gene names	TFF1, BCEI, PS2
Domain Architecture
Description	Trefoil factor 1 precursor (pS2 protein) (HP1.A) (Breast cancer estrogen-inducible protein) (PNR-2).

TFF1_MOUSE
θ value	0.0330416 (rank : 13)	NC score	0.200449 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q08423, Q3TVE6	Gene names	Tff1, Bcei, Ps2
Domain Architecture
Description	Trefoil factor 1 precursor (pS2 protein).

TFF3_HUMAN
θ value	0.0431538 (rank : 14)	NC score	0.201052 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	Q07654	Gene names	TFF3, ITF, TFI
Domain Architecture
Description	Trefoil factor 3 precursor (Intestinal trefoil factor) (hP1.B).

ZP4_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.034129 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q12836	Gene names	ZP4, ZPB
Domain Architecture
Description	Zona pellucida sperm-binding protein 4 precursor (Zona pellucida sperm-binding protein B).

GNAS1_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.004695 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	278	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

VAPA_MOUSE
θ value	4.03905 (rank : 17)	NC score	0.013813 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WV55, Q3TJM1, Q9QY77	Gene names	Vapa, Vap33
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein A (VAMP- associated protein A) (VAMP-A) (VAP-A) (33 kDa Vamp-associated protein) (VAP-33).

GI24_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.013349 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H7M9, Q6UXF3, Q8WUG3, Q8WYZ8	Gene names	C10orf54
Domain Architecture	No domain graphic available
Description	Platelet receptor Gi24 precursor.

LRRC7_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.002772 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	423	Shared Neighborhood Hits	3
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

NADAP_HUMAN
θ value	6.88961 (rank : 20)	NC score	0.012828 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	208	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

ZBTB1_MOUSE
θ value	6.88961 (rank : 21)	NC score	-0.000685 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	795	Shared Neighborhood Hits	2
SwissProt Accessions	Q91VL9, Q8CDP7, Q99LD2	Gene names	Zbtb1
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 1.

ENKUR_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.010556 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q6SP97	Gene names
Domain Architecture	No domain graphic available
Description	Enkurin.

FMOD_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.001998 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	283	Shared Neighborhood Hits	3
SwissProt Accessions	Q06828, Q15331	Gene names	FMOD, FM
Domain Architecture
Description	Fibromodulin precursor (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin).

MUC2_HUMAN
θ value	8.99809 (rank : 24)	NC score	0.002156 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	906	Shared Neighborhood Hits	2
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

RC3H1_MOUSE
θ value	8.99809 (rank : 25)	NC score	0.005536 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	244	Shared Neighborhood Hits	2
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

Hits sorted by NC score

LYAG_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	P70699, Q3UJB2, Q8BGI6, Q91Z45	Gene names	Gaa
Domain Architecture
Description	Lysosomal alpha-glucosidase precursor (EC 3.2.1.20) (Acid maltase).

LYAG_HUMAN
NC score	0.997908 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	24	Shared Neighborhood Hits	15
SwissProt Accessions	P10253, Q14351, Q16302	Gene names	GAA
Domain Architecture
Description	Lysosomal alpha-glucosidase precursor (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Contains: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase].

MGA_HUMAN
NC score	0.961113 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	O43451	Gene names	MGAM, MGA, MGAML
Domain Architecture
Description	Maltase-glucoamylase, intestinal [Includes: Maltase (EC 3.2.1.20) (Alpha-glucosidase); Glucoamylase (EC 3.2.1.3) (Glucan 1,4-alpha- glucosidase)].

SUIS_HUMAN
NC score	0.961107 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	P14410	Gene names	SI
Domain Architecture
Description	Sucrase-isomaltase, intestinal [Contains: Sucrase (EC 3.2.1.48); Isomaltase (EC 3.2.1.10)].

GANC_MOUSE
NC score	0.905306 (rank : 5)	θ value	1.54472e-92 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BVW0, Q8BH03	Gene names	Ganc
Domain Architecture
Description	Neutral alpha-glucosidase C (EC 3.2.1.-).

GANC_HUMAN
NC score	0.902986 (rank : 6)	θ value	7.17548e-90 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TET4, Q52LQ4, Q8IWZ0, Q8IZM4, Q8IZM5	Gene names	GANC
Domain Architecture
Description	Neutral alpha-glucosidase C (EC 3.2.1.20).

GANAB_MOUSE
NC score	0.899157 (rank : 7)	θ value	1.70789e-91 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BHN3, O08794, Q80U81, Q9CS53	Gene names	Ganab, G2an, Kiaa0088
Domain Architecture
Description	Neutral alpha-glucosidase AB precursor (EC 3.2.1.84) (Glucosidase II subunit alpha) (Alpha glucosidase 2).

GANAB_HUMAN
NC score	0.899057 (rank : 8)	θ value	5.14231e-88 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q14697, Q8WTS9, Q9P0X0	Gene names	GANAB, G2AN, KIAA0088
Domain Architecture
Description	Neutral alpha-glucosidase AB precursor (EC 3.2.1.84) (Glucosidase II subunit alpha).

TFF3_MOUSE
NC score	0.229763 (rank : 9)	θ value	0.00175202 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q62395, Q64352	Gene names	Tff3, Itf
Domain Architecture
Description	Trefoil factor 3 precursor (Intestinal trefoil factor).

TFF3_HUMAN
NC score	0.201052 (rank : 10)	θ value	0.0431538 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	Q07654	Gene names	TFF3, ITF, TFI
Domain Architecture
Description	Trefoil factor 3 precursor (Intestinal trefoil factor) (hP1.B).

TFF1_MOUSE
NC score	0.200449 (rank : 11)	θ value	0.0330416 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q08423, Q3TVE6	Gene names	Tff1, Bcei, Ps2
Domain Architecture
Description	Trefoil factor 1 precursor (pS2 protein).

TFF1_HUMAN
NC score	0.195523 (rank : 12)	θ value	0.0148317 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	P04155	Gene names	TFF1, BCEI, PS2
Domain Architecture
Description	Trefoil factor 1 precursor (pS2 protein) (HP1.A) (Breast cancer estrogen-inducible protein) (PNR-2).

TFF2_HUMAN
NC score	0.178581 (rank : 13)	θ value	0.00390308 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q03403, Q15854	Gene names	TFF2, SML1
Domain Architecture
Description	Trefoil factor 2 precursor (Spasmolytic polypeptide) (SP) (Spasmolysin).

TFF2_MOUSE
NC score	0.163680 (rank : 14)	θ value	0.00665767 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q03404, O08913	Gene names	Tff2, Sml1, Sp
Domain Architecture
Description	Trefoil factor 2 precursor (Spasmolytic polypeptide) (SP).

ZP4_HUMAN
NC score	0.034129 (rank : 15)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q12836	Gene names	ZP4, ZPB
Domain Architecture
Description	Zona pellucida sperm-binding protein 4 precursor (Zona pellucida sperm-binding protein B).

VAPA_MOUSE
NC score	0.013813 (rank : 16)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WV55, Q3TJM1, Q9QY77	Gene names	Vapa, Vap33
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein A (VAMP- associated protein A) (VAMP-A) (VAP-A) (33 kDa Vamp-associated protein) (VAP-33).

GI24_HUMAN
NC score	0.013349 (rank : 17)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H7M9, Q6UXF3, Q8WUG3, Q8WYZ8	Gene names	C10orf54
Domain Architecture	No domain graphic available
Description	Platelet receptor Gi24 precursor.

NADAP_HUMAN
NC score	0.012828 (rank : 18)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	208	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

ENKUR_MOUSE
NC score	0.010556 (rank : 19)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q6SP97	Gene names
Domain Architecture	No domain graphic available
Description	Enkurin.

RC3H1_MOUSE
NC score	0.005536 (rank : 20)	θ value	8.99809 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	244	Shared Neighborhood Hits	2
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

GNAS1_HUMAN
NC score	0.004695 (rank : 21)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	278	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

LRRC7_HUMAN
NC score	0.002772 (rank : 22)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	423	Shared Neighborhood Hits	3
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

MUC2_HUMAN
NC score	0.002156 (rank : 23)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	906	Shared Neighborhood Hits	2
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

FMOD_HUMAN
NC score	0.001998 (rank : 24)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	283	Shared Neighborhood Hits	3
SwissProt Accessions	Q06828, Q15331	Gene names	FMOD, FM
Domain Architecture
Description	Fibromodulin precursor (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin).

ZBTB1_MOUSE
NC score	-0.000685 (rank : 25)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	795	Shared Neighborhood Hits	2
SwissProt Accessions	Q91VL9, Q8CDP7, Q99LD2	Gene names	Zbtb1
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 1.