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Network neighborhood for query Sequence : TDRD5_HUMAN

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TDRD5_HUMAN
SwissProt Accessions	Q8NAT2, Q5VTV0	Gene names	TDRD5
Domain Architecture
Description	Tudor domain-containing protein 5.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TDRD5_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NAT2, Q5VTV0	Gene names	TDRD5
Domain Architecture
Description	Tudor domain-containing protein 5.

TDRKH_MOUSE
θ value	1.80466e-16 (rank : 2)	NC score	0.551629 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	15
SwissProt Accessions	Q80VL1	Gene names	Tdrkh
Domain Architecture
Description	Tudor and KH domain-containing protein.

TDRKH_HUMAN
θ value	5.25075e-16 (rank : 3)	NC score	0.547195 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y2W6, Q8N582, Q9NYV5	Gene names	TDRKH, TDRD2
Domain Architecture
Description	Tudor and KH domain-containing protein.

TDRD1_HUMAN
θ value	4.44505e-15 (rank : 4)	NC score	0.610466 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	24	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BXT4, Q9H7B3	Gene names	TDRD1
Domain Architecture
Description	Tudor domain-containing protein 1.

TDRD1_MOUSE
θ value	1.42992e-13 (rank : 5)	NC score	0.589293 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	37	Shared Neighborhood Hits	15
SwissProt Accessions	Q99MV1	Gene names	Tdrd1
Domain Architecture
Description	Tudor domain-containing protein 1.

TDRD6_MOUSE
θ value	4.30538e-10 (rank : 6)	NC score	0.503809 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	82	Shared Neighborhood Hits	17
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

AKAP1_MOUSE
θ value	1.43324e-05 (rank : 7)	NC score	0.369894 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	198	Shared Neighborhood Hits	19
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

TDRD7_HUMAN
θ value	1.87187e-05 (rank : 8)	NC score	0.426537 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	40	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NHU6, Q96JT1, Q9UFF0, Q9Y2M3	Gene names	TDRD7, PCTAIRE2BP
Domain Architecture
Description	Tudor domain-containing protein 7 (Tudor repeat associator with PCTAIRE 2) (Trap).

TDRD7_MOUSE
θ value	2.44474e-05 (rank : 9)	NC score	0.431957 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	39	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K1H1, Q8R181	Gene names	Tdrd7, Pctaire2bp
Domain Architecture
Description	Tudor domain-containing protein 7 (Tudor repeat associator with PCTAIRE 2) (Trap).

AKAP1_HUMAN
θ value	0.000121331 (rank : 10)	NC score	0.375762 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	88	Shared Neighborhood Hits	16
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

SND1_MOUSE
θ value	0.000270298 (rank : 11)	NC score	0.339473 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	31	Shared Neighborhood Hits	15
SwissProt Accessions	Q78PY7, Q3TT46, Q922L5, Q9R0S1	Gene names	Snd1
Domain Architecture	No domain graphic available
Description	Staphylococcal nuclease domain-containing protein 1 (p100 co- activator) (100 kDa coactivator).

SND1_HUMAN
θ value	0.00035302 (rank : 12)	NC score	0.341603 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q7KZF4, Q13122	Gene names	SND1
Domain Architecture	No domain graphic available
Description	Staphylococcal nuclease domain-containing protein 1 (p100 co- activator) (100 kDa coactivator) (EBNA2 coactivator p100).

STK31_HUMAN
θ value	0.0193708 (rank : 13)	NC score	0.139677 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	570	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

K0423_MOUSE
θ value	0.0563607 (rank : 14)	NC score	0.073843 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

EPIPL_MOUSE
θ value	0.0736092 (rank : 15)	NC score	0.054535 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0W0	Gene names	Eppk1
Domain Architecture
Description	Epiplakin.

RNF17_MOUSE
θ value	0.125558 (rank : 16)	NC score	0.086463 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	147	Shared Neighborhood Hits	8
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

SYTL2_MOUSE
θ value	0.163984 (rank : 17)	NC score	0.034925 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	253	Shared Neighborhood Hits	7
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

CENPU_MOUSE
θ value	0.21417 (rank : 18)	NC score	0.073600 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C4M7, Q6UNA2, Q9D9U1	Gene names	Mlf1ip, Cenpu
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (MLF1-interacting protein).

TDRD4_HUMAN
θ value	0.279714 (rank : 19)	NC score	0.315598 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	33	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NUY9	Gene names	TDRD4
Domain Architecture
Description	Tudor domain-containing protein 4.

CHD9_MOUSE
θ value	1.06291 (rank : 20)	NC score	0.017894 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	427	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

FA76A_MOUSE
θ value	1.06291 (rank : 21)	NC score	0.049942 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q922G2, Q3U3U8, Q3V3N2	Gene names	Fam76a
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

STK31_MOUSE
θ value	1.06291 (rank : 22)	NC score	0.125411 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	474	Shared Neighborhood Hits	15
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

FA44A_HUMAN
θ value	1.38821 (rank : 23)	NC score	0.041187 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	280	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

HUWE1_HUMAN
θ value	1.38821 (rank : 24)	NC score	0.031372 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	443	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

HUWE1_MOUSE
θ value	1.38821 (rank : 25)	NC score	0.031472 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	406	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

LIPA4_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.025594 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	O75335, O94971	Gene names	PPFIA4, KIAA0897
Domain Architecture
Description	Liprin-alpha-4 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4) (PTPRF-interacting protein alpha-4).

ORC1_MOUSE
θ value	1.38821 (rank : 27)	NC score	0.039446 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1N2	Gene names	Orc1l, Orc1
Domain Architecture
Description	Origin recognition complex subunit 1.

BICD2_HUMAN
θ value	1.81305 (rank : 28)	NC score	0.023241 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	856	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.022508 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	864	Shared Neighborhood Hits	11
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

NCOA6_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.029928 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	1202	Shared Neighborhood Hits	9
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

CDYL1_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.020441 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y232	Gene names	CDYL, CDYL1
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

FA76A_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.044742 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	149	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TAV0, O95565, O95566, Q8N7J5	Gene names	FAM76A
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

TACC2_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.024318 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	856	Shared Neighborhood Hits	12
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

THA11_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.049694 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EK4, O94795	Gene names	THAP11
Domain Architecture
Description	THAP domain-containing protein 11.

ZCH10_MOUSE
θ value	2.36792 (rank : 35)	NC score	0.053926 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	133	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

BRCA2_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.027664 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	202	Shared Neighborhood Hits	5
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

DOCK8_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.018397 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C147, Q6PIS0, Q7TMQ5, Q8K105, Q9DBQ2	Gene names	Dock8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

DSPP_MOUSE
θ value	3.0926 (rank : 38)	NC score	0.037379 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	491	Shared Neighborhood Hits	13
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

JHD1B_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.016501 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

LEO1_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.026685 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	958	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

NCOA6_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.031078 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	1076	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PGBM_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.006528 (rank : 72)
Query Neighborhood Hits	65	Target Neighborhood Hits	1073	Shared Neighborhood Hits	5
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SDK2_MOUSE
θ value	3.0926 (rank : 43)	NC score	0.008524 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	480	Shared Neighborhood Hits	4
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

FBX38_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.028182 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BMI0, Q8BTQ4, Q8C0H4	Gene names	Fbxo38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity) (MoKA).

FMN2_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.015895 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	484	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

STAG3_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.017239 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	O70576	Gene names	Stag3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

TOP2A_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.019486 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	135	Shared Neighborhood Hits	6
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

CENPJ_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.019591 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	721	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

CT032_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.018549 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

DSPP_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.030598 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	645	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

NEST_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.011338 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	1305	Shared Neighborhood Hits	17
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

S12A2_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.012036 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	P55012	Gene names	Slc12a2, Nkcc1
Domain Architecture
Description	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).

TACC2_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.024132 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	774	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TNR6A_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.030384 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	343	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

AKAP2_MOUSE
θ value	6.88961 (rank : 55)	NC score	0.020981 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	385	Shared Neighborhood Hits	11
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

GCM2_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.018591 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	O75603	Gene names	GCM2, GCMB
Domain Architecture
Description	Chorion-specific transcription factor GCMb (Glial cells missing homolog 2) (GCM motif protein 2) (hGCMb).

NASP_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.019473 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	709	Shared Neighborhood Hits	14
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

AFF1_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.016540 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	351	Shared Neighborhood Hits	9
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

APC_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.016499 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	441	Shared Neighborhood Hits	11
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

CAF1A_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.014818 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	750	Shared Neighborhood Hits	14
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CI039_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.010739 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	1171	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

MINT_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.011697 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	1514	Shared Neighborhood Hits	21
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MY18A_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.005467 (rank : 73)
Query Neighborhood Hits	65	Target Neighborhood Hits	1929	Shared Neighborhood Hits	24
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYBPH_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.009590 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	290	Shared Neighborhood Hits	5
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

ROCK2_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.001294 (rank : 74)
Query Neighborhood Hits	65	Target Neighborhood Hits	2072	Shared Neighborhood Hits	16
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

FUBP1_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.064323 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

FUBP1_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.064475 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	144	Shared Neighborhood Hits	5
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

FUBP2_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.059168 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	145	Shared Neighborhood Hits	5
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

FUBP3_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.068834 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

IF2B2_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.053735 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

IF2B2_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.055551 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	148	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SF07, Q3TCU4, Q7TQF9	Gene names	Igf2bp2, Imp2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2).

NOVA1_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.072657 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

NOVA2_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.086827 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNW9, O43267, Q9UEA1	Gene names	NOVA2, ANOVA, NOVA3
Domain Architecture
Description	RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2) (Astrocytic NOVA1-like RNA-binding protein).

RNF17_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.050016 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXT8, Q9BXT7	Gene names	RNF17
Domain Architecture
Description	RING finger protein 17.

Hits sorted by NC score

TDRD5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NAT2, Q5VTV0	Gene names	TDRD5
Domain Architecture
Description	Tudor domain-containing protein 5.

TDRD1_HUMAN
NC score	0.610466 (rank : 2)	θ value	4.44505e-15 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	24	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BXT4, Q9H7B3	Gene names	TDRD1
Domain Architecture
Description	Tudor domain-containing protein 1.

TDRD1_MOUSE
NC score	0.589293 (rank : 3)	θ value	1.42992e-13 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	37	Shared Neighborhood Hits	15
SwissProt Accessions	Q99MV1	Gene names	Tdrd1
Domain Architecture
Description	Tudor domain-containing protein 1.

TDRKH_MOUSE
NC score	0.551629 (rank : 4)	θ value	1.80466e-16 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	15
SwissProt Accessions	Q80VL1	Gene names	Tdrkh
Domain Architecture
Description	Tudor and KH domain-containing protein.

TDRKH_HUMAN
NC score	0.547195 (rank : 5)	θ value	5.25075e-16 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y2W6, Q8N582, Q9NYV5	Gene names	TDRKH, TDRD2
Domain Architecture
Description	Tudor and KH domain-containing protein.

TDRD6_MOUSE
NC score	0.503809 (rank : 6)	θ value	4.30538e-10 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	82	Shared Neighborhood Hits	17
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

TDRD7_MOUSE
NC score	0.431957 (rank : 7)	θ value	2.44474e-05 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	39	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K1H1, Q8R181	Gene names	Tdrd7, Pctaire2bp
Domain Architecture
Description	Tudor domain-containing protein 7 (Tudor repeat associator with PCTAIRE 2) (Trap).

TDRD7_HUMAN
NC score	0.426537 (rank : 8)	θ value	1.87187e-05 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	40	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NHU6, Q96JT1, Q9UFF0, Q9Y2M3	Gene names	TDRD7, PCTAIRE2BP
Domain Architecture
Description	Tudor domain-containing protein 7 (Tudor repeat associator with PCTAIRE 2) (Trap).

AKAP1_HUMAN
NC score	0.375762 (rank : 9)	θ value	0.000121331 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	88	Shared Neighborhood Hits	16
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

AKAP1_MOUSE
NC score	0.369894 (rank : 10)	θ value	1.43324e-05 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	198	Shared Neighborhood Hits	19
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

SND1_HUMAN
NC score	0.341603 (rank : 11)	θ value	0.00035302 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q7KZF4, Q13122	Gene names	SND1
Domain Architecture	No domain graphic available
Description	Staphylococcal nuclease domain-containing protein 1 (p100 co- activator) (100 kDa coactivator) (EBNA2 coactivator p100).

SND1_MOUSE
NC score	0.339473 (rank : 12)	θ value	0.000270298 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	31	Shared Neighborhood Hits	15
SwissProt Accessions	Q78PY7, Q3TT46, Q922L5, Q9R0S1	Gene names	Snd1
Domain Architecture	No domain graphic available
Description	Staphylococcal nuclease domain-containing protein 1 (p100 co- activator) (100 kDa coactivator).

TDRD4_HUMAN
NC score	0.315598 (rank : 13)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	33	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NUY9	Gene names	TDRD4
Domain Architecture
Description	Tudor domain-containing protein 4.

STK31_HUMAN
NC score	0.139677 (rank : 14)	θ value	0.0193708 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	570	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

STK31_MOUSE
NC score	0.125411 (rank : 15)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	474	Shared Neighborhood Hits	15
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

NOVA2_HUMAN
NC score	0.086827 (rank : 16)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	65	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNW9, O43267, Q9UEA1	Gene names	NOVA2, ANOVA, NOVA3
Domain Architecture
Description	RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2) (Astrocytic NOVA1-like RNA-binding protein).

RNF17_MOUSE
NC score	0.086463 (rank : 17)	θ value	0.125558 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	147	Shared Neighborhood Hits	8
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

K0423_MOUSE
NC score	0.073843 (rank : 18)	θ value	0.0563607 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

CENPU_MOUSE
NC score	0.073600 (rank : 19)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C4M7, Q6UNA2, Q9D9U1	Gene names	Mlf1ip, Cenpu
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (MLF1-interacting protein).

NOVA1_HUMAN
NC score	0.072657 (rank : 20)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	65	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

FUBP3_HUMAN
NC score	0.068834 (rank : 21)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

FUBP1_MOUSE
NC score	0.064475 (rank : 22)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	144	Shared Neighborhood Hits	5
SwissProt Accessions	Q91WJ8, Q8C0Y8	Gene names	Fubp1, D3Ertd330e
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP).

FUBP1_HUMAN
NC score	0.064323 (rank : 23)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	Q96AE4, Q12828	Gene names	FUBP1
Domain Architecture
Description	Far upstream element-binding protein 1 (FUSE-binding protein 1) (FBP) (DNA helicase V) (HDH V).

FUBP2_HUMAN
NC score	0.059168 (rank : 24)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	145	Shared Neighborhood Hits	5
SwissProt Accessions	Q92945, O00301, Q9UNT5, Q9UQH5	Gene names	KHSRP, FUBP2
Domain Architecture
Description	Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75).

IF2B2_MOUSE
NC score	0.055551 (rank : 25)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	148	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SF07, Q3TCU4, Q7TQF9	Gene names	Igf2bp2, Imp2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2).

EPIPL_MOUSE
NC score	0.054535 (rank : 26)	θ value	0.0736092 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0W0	Gene names	Eppk1
Domain Architecture
Description	Epiplakin.

ZCH10_MOUSE
NC score	0.053926 (rank : 27)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	133	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

IF2B2_HUMAN
NC score	0.053735 (rank : 28)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6M1	Gene names	IGF2BP2, IMP2
Domain Architecture	No domain graphic available
Description	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF-II mRNA- binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62).

RNF17_HUMAN
NC score	0.050016 (rank : 29)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXT8, Q9BXT7	Gene names	RNF17
Domain Architecture
Description	RING finger protein 17.

FA76A_MOUSE
NC score	0.049942 (rank : 30)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q922G2, Q3U3U8, Q3V3N2	Gene names	Fam76a
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

THA11_HUMAN
NC score	0.049694 (rank : 31)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EK4, O94795	Gene names	THAP11
Domain Architecture
Description	THAP domain-containing protein 11.

FA76A_HUMAN
NC score	0.044742 (rank : 32)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	149	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TAV0, O95565, O95566, Q8N7J5	Gene names	FAM76A
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

FA44A_HUMAN
NC score	0.041187 (rank : 33)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	280	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

ORC1_MOUSE
NC score	0.039446 (rank : 34)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1N2	Gene names	Orc1l, Orc1
Domain Architecture
Description	Origin recognition complex subunit 1.

DSPP_MOUSE
NC score	0.037379 (rank : 35)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	491	Shared Neighborhood Hits	13
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

SYTL2_MOUSE
NC score	0.034925 (rank : 36)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	253	Shared Neighborhood Hits	7
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

HUWE1_MOUSE
NC score	0.031472 (rank : 37)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	406	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

HUWE1_HUMAN
NC score	0.031372 (rank : 38)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	443	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

NCOA6_MOUSE
NC score	0.031078 (rank : 39)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	1076	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

DSPP_HUMAN
NC score	0.030598 (rank : 40)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	645	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

TNR6A_HUMAN
NC score	0.030384 (rank : 41)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	343	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

NCOA6_HUMAN
NC score	0.029928 (rank : 42)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	1202	Shared Neighborhood Hits	9
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

FBX38_MOUSE
NC score	0.028182 (rank : 43)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BMI0, Q8BTQ4, Q8C0H4	Gene names	Fbxo38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity) (MoKA).

BRCA2_HUMAN
NC score	0.027664 (rank : 44)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	202	Shared Neighborhood Hits	5
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

LEO1_HUMAN
NC score	0.026685 (rank : 45)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	958	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LIPA4_HUMAN
NC score	0.025594 (rank : 46)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	O75335, O94971	Gene names	PPFIA4, KIAA0897
Domain Architecture
Description	Liprin-alpha-4 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4) (PTPRF-interacting protein alpha-4).

TACC2_HUMAN
NC score	0.024318 (rank : 47)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	856	Shared Neighborhood Hits	12
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TACC2_MOUSE
NC score	0.024132 (rank : 48)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	774	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

BICD2_HUMAN
NC score	0.023241 (rank : 49)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	856	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_MOUSE
NC score	0.022508 (rank : 50)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	864	Shared Neighborhood Hits	11
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

AKAP2_MOUSE
NC score	0.020981 (rank : 51)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	385	Shared Neighborhood Hits	11
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

CDYL1_HUMAN
NC score	0.020441 (rank : 52)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y232	Gene names	CDYL, CDYL1
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CENPJ_HUMAN
NC score	0.019591 (rank : 53)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	721	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HC77, Q5T6R5, Q96KS5, Q9C067	Gene names	CENPJ, CPAP, LAP, LIP1
Domain Architecture	No domain graphic available
Description	Centromere protein J (CENP-J) (Centrosomal P4.1-associated protein) (LAG-3-associated protein) (LYST-interacting protein 1).

TOP2A_HUMAN
NC score	0.019486 (rank : 54)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	135	Shared Neighborhood Hits	6
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

NASP_HUMAN
NC score	0.019473 (rank : 55)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	709	Shared Neighborhood Hits	14
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

GCM2_HUMAN
NC score	0.018591 (rank : 56)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	O75603	Gene names	GCM2, GCMB
Domain Architecture
Description	Chorion-specific transcription factor GCMb (Glial cells missing homolog 2) (GCM motif protein 2) (hGCMb).

CT032_HUMAN
NC score	0.018549 (rank : 57)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

DOCK8_MOUSE
NC score	0.018397 (rank : 58)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C147, Q6PIS0, Q7TMQ5, Q8K105, Q9DBQ2	Gene names	Dock8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

CHD9_MOUSE
NC score	0.017894 (rank : 59)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	427	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

STAG3_MOUSE
NC score	0.017239 (rank : 60)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	O70576	Gene names	Stag3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

AFF1_MOUSE
NC score	0.016540 (rank : 61)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	351	Shared Neighborhood Hits	9
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

JHD1B_HUMAN
NC score	0.016501 (rank : 62)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

APC_MOUSE
NC score	0.016499 (rank : 63)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	441	Shared Neighborhood Hits	11
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

FMN2_HUMAN
NC score	0.015895 (rank : 64)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	484	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

CAF1A_HUMAN
NC score	0.014818 (rank : 65)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	750	Shared Neighborhood Hits	14
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

S12A2_MOUSE
NC score	0.012036 (rank : 66)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	P55012	Gene names	Slc12a2, Nkcc1
Domain Architecture
Description	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).

MINT_MOUSE
NC score	0.011697 (rank : 67)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	1514	Shared Neighborhood Hits	21
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NEST_HUMAN
NC score	0.011338 (rank : 68)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	1305	Shared Neighborhood Hits	17
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

CI039_HUMAN
NC score	0.010739 (rank : 69)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	1171	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

MYBPH_MOUSE
NC score	0.009590 (rank : 70)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	290	Shared Neighborhood Hits	5
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

SDK2_MOUSE
NC score	0.008524 (rank : 71)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	480	Shared Neighborhood Hits	4
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

PGBM_MOUSE
NC score	0.006528 (rank : 72)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	1073	Shared Neighborhood Hits	5
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

MY18A_HUMAN
NC score	0.005467 (rank : 73)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	1929	Shared Neighborhood Hits	24
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

ROCK2_MOUSE
NC score	0.001294 (rank : 74)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	2072	Shared Neighborhood Hits	16
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).