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Network neighborhood for query Sequence : SP17_HUMAN

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SP17_HUMAN
SwissProt Accessions	Q15506, Q9BXF7	Gene names	SPA17, SP17
Domain Architecture
Description	Sperm surface protein Sp17 (Sperm autoantigenic protein 17) (Sperm protein 17) (Sp17-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SP17_HUMAN
θ value	1.7756e-72 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q15506, Q9BXF7	Gene names	SPA17, SP17
Domain Architecture
Description	Sperm surface protein Sp17 (Sperm autoantigenic protein 17) (Sperm protein 17) (Sp17-1).

SP17_MOUSE
θ value	1.23823e-49 (rank : 2)	NC score	0.972040 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	17
SwissProt Accessions	Q62252	Gene names	Spa17, Sp17
Domain Architecture
Description	Sperm surface protein Sp17 (Sperm autoantigenic protein 17).

CABYR_HUMAN
θ value	9.29e-05 (rank : 3)	NC score	0.355483 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

KAP2_HUMAN
θ value	9.29e-05 (rank : 4)	NC score	0.226644 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

CABYR_MOUSE
θ value	0.000786445 (rank : 5)	NC score	0.325482 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	80	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

KAP3_HUMAN
θ value	0.0563607 (rank : 6)	NC score	0.189033 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	40	Shared Neighborhood Hits	7
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_MOUSE
θ value	0.0563607 (rank : 7)	NC score	0.188571 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	43	Shared Neighborhood Hits	7
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

NEUM_HUMAN
θ value	0.0961366 (rank : 8)	NC score	0.138655 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

SCN8A_HUMAN
θ value	0.0961366 (rank : 9)	NC score	0.062499 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
θ value	0.125558 (rank : 10)	NC score	0.061563 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

KAP2_MOUSE
θ value	0.279714 (rank : 11)	NC score	0.179933 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

DPOLZ_MOUSE
θ value	0.62314 (rank : 12)	NC score	0.048651 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	169	Shared Neighborhood Hits	3
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

MYO3A_HUMAN
θ value	0.813845 (rank : 13)	NC score	0.011981 (rank : 35)
Query Neighborhood Hits	34	Target Neighborhood Hits	1033	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

OFD1_HUMAN
θ value	1.81305 (rank : 14)	NC score	0.027874 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	753	Shared Neighborhood Hits	7
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

NEUM_MOUSE
θ value	2.36792 (rank : 15)	NC score	0.089216 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	149	Shared Neighborhood Hits	6
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

GALT5_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.013273 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z7M9, Q9UGK7, Q9UHL6	Gene names	GALNT5
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 5 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) (Polypeptide GalNAc transferase 5) (GalNAc-T5) (pp-GaNTase 5).

TCRG1_HUMAN
θ value	3.0926 (rank : 17)	NC score	0.034941 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	929	Shared Neighborhood Hits	10
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	3.0926 (rank : 18)	NC score	0.034268 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	947	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

FA13A_HUMAN
θ value	4.03905 (rank : 19)	NC score	0.024706 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

LRC27_HUMAN
θ value	4.03905 (rank : 20)	NC score	0.019936 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	710	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

NEUG_HUMAN
θ value	4.03905 (rank : 21)	NC score	0.157906 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	9	Shared Neighborhood Hits	7
SwissProt Accessions	Q92686	Gene names	NRGN
Domain Architecture	No domain graphic available
Description	Neurogranin (Ng) (RC3).

NEUG_MOUSE
θ value	4.03905 (rank : 22)	NC score	0.151734 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	P60761, Q3TYH4	Gene names	Nrgn
Domain Architecture	No domain graphic available
Description	Neurogranin (Ng) (RC3).

RPGR_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.020910 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	281	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

HNRPQ_HUMAN
θ value	5.27518 (rank : 24)	NC score	0.027025 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	O60506, Q53H05, Q5TCG2, Q8IW78, Q8N599, Q96LC1, Q96LC2, Q9Y583	Gene names	SYNCRIP, HNRPQ, NSAP1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (hnRNP-Q) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1).

HNRPQ_MOUSE
θ value	5.27518 (rank : 25)	NC score	0.027139 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TMK9, O88991, Q80YV6, Q8BGP1, Q8C5K6, Q8CGC2, Q91ZR0, Q99KU9, Q9QYF4	Gene names	Syncrip, Hnrpq, Nsap1, Nsap1l
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (hnRNP-Q) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (pp68).

NIN_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.011690 (rank : 36)
Query Neighborhood Hits	34	Target Neighborhood Hits	1416	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

RPGR1_MOUSE
θ value	5.27518 (rank : 27)	NC score	0.021896 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	713	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

ADA30_HUMAN
θ value	6.88961 (rank : 28)	NC score	0.007562 (rank : 37)
Query Neighborhood Hits	34	Target Neighborhood Hits	391	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

IQGA1_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.015629 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	250	Shared Neighborhood Hits	5
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

TRAK1_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.015101 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	660	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

LDB1_HUMAN
θ value	8.99809 (rank : 31)	NC score	0.024616 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q86U70, O96010, Q9UGM4	Gene names	LDB1, CLIM2
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 1 (Carboxyl-terminal LIM domain-binding protein 2) (CLIM-2) (LIM domain-binding factor CLIM2).

LDB1_MOUSE
θ value	8.99809 (rank : 32)	NC score	0.024612 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P70662	Gene names	Ldb1, Nli
Domain Architecture
Description	LIM domain-binding protein 1 (Nuclear LIM interactor).

OBSCN_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.002824 (rank : 38)
Query Neighborhood Hits	34	Target Neighborhood Hits	1931	Shared Neighborhood Hits	7
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

SCN2A_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.049446 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

KAP0_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.093655 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP0_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.094153 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.094123 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.094281 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

Hits sorted by NC score

SP17_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.7756e-72 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q15506, Q9BXF7	Gene names	SPA17, SP17
Domain Architecture
Description	Sperm surface protein Sp17 (Sperm autoantigenic protein 17) (Sperm protein 17) (Sp17-1).

SP17_MOUSE
NC score	0.972040 (rank : 2)	θ value	1.23823e-49 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	17
SwissProt Accessions	Q62252	Gene names	Spa17, Sp17
Domain Architecture
Description	Sperm surface protein Sp17 (Sperm autoantigenic protein 17).

CABYR_HUMAN
NC score	0.355483 (rank : 3)	θ value	9.29e-05 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	O75952, Q8WXW5, Q9HAY3, Q9HAY4, Q9HAY5, Q9HCY9	Gene names	CABYR, CBP86, FSP2
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86) (Fibrousheathin-2) (FSP-2).

CABYR_MOUSE
NC score	0.325482 (rank : 4)	θ value	0.000786445 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	80	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D424, Q91Y41, Q91Y42	Gene names	Cabyr, Cbp86
Domain Architecture	No domain graphic available
Description	Calcium-binding tyrosine phosphorylation-regulated protein (Calcium- binding protein 86) (Testis-specific calcium-binding protein CBP86).

KAP2_HUMAN
NC score	0.226644 (rank : 5)	θ value	9.29e-05 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_HUMAN
NC score	0.189033 (rank : 6)	θ value	0.0563607 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	40	Shared Neighborhood Hits	7
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_MOUSE
NC score	0.188571 (rank : 7)	θ value	0.0563607 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	43	Shared Neighborhood Hits	7
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP2_MOUSE
NC score	0.179933 (rank : 8)	θ value	0.279714 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

NEUG_HUMAN
NC score	0.157906 (rank : 9)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	9	Shared Neighborhood Hits	7
SwissProt Accessions	Q92686	Gene names	NRGN
Domain Architecture	No domain graphic available
Description	Neurogranin (Ng) (RC3).

NEUG_MOUSE
NC score	0.151734 (rank : 10)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	P60761, Q3TYH4	Gene names	Nrgn
Domain Architecture	No domain graphic available
Description	Neurogranin (Ng) (RC3).

NEUM_HUMAN
NC score	0.138655 (rank : 11)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

KAP1_MOUSE
NC score	0.094281 (rank : 12)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	34	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP0_MOUSE
NC score	0.094153 (rank : 13)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	34	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_HUMAN
NC score	0.094123 (rank : 14)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	34	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP0_HUMAN
NC score	0.093655 (rank : 15)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	34	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

NEUM_MOUSE
NC score	0.089216 (rank : 16)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	149	Shared Neighborhood Hits	6
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

SCN8A_HUMAN
NC score	0.062499 (rank : 17)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
NC score	0.061563 (rank : 18)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN2A_HUMAN
NC score	0.049446 (rank : 19)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

DPOLZ_MOUSE
NC score	0.048651 (rank : 20)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	169	Shared Neighborhood Hits	3
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

TCRG1_HUMAN
NC score	0.034941 (rank : 21)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	929	Shared Neighborhood Hits	10
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
NC score	0.034268 (rank : 22)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	947	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

OFD1_HUMAN
NC score	0.027874 (rank : 23)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	753	Shared Neighborhood Hits	7
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

HNRPQ_MOUSE
NC score	0.027139 (rank : 24)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TMK9, O88991, Q80YV6, Q8BGP1, Q8C5K6, Q8CGC2, Q91ZR0, Q99KU9, Q9QYF4	Gene names	Syncrip, Hnrpq, Nsap1, Nsap1l
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (hnRNP-Q) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (pp68).

HNRPQ_HUMAN
NC score	0.027025 (rank : 25)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	O60506, Q53H05, Q5TCG2, Q8IW78, Q8N599, Q96LC1, Q96LC2, Q9Y583	Gene names	SYNCRIP, HNRPQ, NSAP1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (hnRNP-Q) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1).

FA13A_HUMAN
NC score	0.024706 (rank : 26)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

LDB1_HUMAN
NC score	0.024616 (rank : 27)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q86U70, O96010, Q9UGM4	Gene names	LDB1, CLIM2
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 1 (Carboxyl-terminal LIM domain-binding protein 2) (CLIM-2) (LIM domain-binding factor CLIM2).

LDB1_MOUSE
NC score	0.024612 (rank : 28)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P70662	Gene names	Ldb1, Nli
Domain Architecture
Description	LIM domain-binding protein 1 (Nuclear LIM interactor).

RPGR1_MOUSE
NC score	0.021896 (rank : 29)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	713	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RPGR_MOUSE
NC score	0.020910 (rank : 30)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	281	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

LRC27_HUMAN
NC score	0.019936 (rank : 31)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	710	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

IQGA1_HUMAN
NC score	0.015629 (rank : 32)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	250	Shared Neighborhood Hits	5
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

TRAK1_HUMAN
NC score	0.015101 (rank : 33)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	660	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

GALT5_HUMAN
NC score	0.013273 (rank : 34)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z7M9, Q9UGK7, Q9UHL6	Gene names	GALNT5
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 5 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) (Polypeptide GalNAc transferase 5) (GalNAc-T5) (pp-GaNTase 5).

MYO3A_HUMAN
NC score	0.011981 (rank : 35)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	1033	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

NIN_HUMAN
NC score	0.011690 (rank : 36)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	1416	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

ADA30_HUMAN
NC score	0.007562 (rank : 37)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	391	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

OBSCN_HUMAN
NC score	0.002824 (rank : 38)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	1931	Shared Neighborhood Hits	7
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).