Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : PDK4_MOUSE

For an explanation of this page, click here

PDK4_MOUSE
SwissProt Accessions	O70571	Gene names	Pdk4
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PDK4_HUMAN
θ value	0 (rank : 1)	NC score	0.999577 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	Q16654	Gene names	PDK4
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4).

PDK4_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	O70571	Gene names	Pdk4
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4).

PDK1_HUMAN
θ value	2.95243e-160 (rank : 3)	NC score	0.996415 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q15118	Gene names	PDK1
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1).

PDK2_MOUSE
θ value	1.62005e-158 (rank : 4)	NC score	0.996499 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JK42	Gene names	Pdk2
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2).

PDK2_HUMAN
θ value	2.76339e-158 (rank : 5)	NC score	0.996507 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q15119, Q9BS05	Gene names	PDK2
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2).

PDK1_MOUSE
θ value	1.37145e-157 (rank : 6)	NC score	0.995883 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BFP9	Gene names	Pdk1
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1).

PDK3_MOUSE
θ value	4.72459e-150 (rank : 7)	NC score	0.994801 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q922H2, Q8BTX1	Gene names	Pdk3
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3).

PDK3_HUMAN
θ value	1.37464e-149 (rank : 8)	NC score	0.994851 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q15120	Gene names	PDK3
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3).

BCKD_HUMAN
θ value	3.16345e-37 (rank : 9)	NC score	0.877842 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	O14874, Q96IN5	Gene names	BCKDK
Domain Architecture
Description	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKDHKIN) (BCKD-kinase).

BCKD_MOUSE
θ value	9.20422e-37 (rank : 10)	NC score	0.876922 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	O55028	Gene names	Bckdk
Domain Architecture
Description	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKDHKIN) (BCKD-kinase).

ATRX_HUMAN
θ value	3.0926 (rank : 11)	NC score	0.005949 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	842	Shared Neighborhood Hits	2
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CT128_HUMAN
θ value	4.03905 (rank : 12)	NC score	0.015988 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BQN1, Q5JWN6, Q8N276	Gene names	C20orf128
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf128.

SPT6H_MOUSE
θ value	4.03905 (rank : 13)	NC score	0.017280 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

CCD22_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.008581 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	268	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JIG7, Q8BYH4	Gene names	Ccdc22, DXImx40e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

M3K4_MOUSE
θ value	6.88961 (rank : 15)	NC score	-0.000556 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	924	Shared Neighborhood Hits	3
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

SPT6H_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.015912 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

TCF20_MOUSE
θ value	6.88961 (rank : 17)	NC score	0.006293 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	396	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

M3K4_HUMAN
θ value	8.99809 (rank : 18)	NC score	-0.000730 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	911	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

Hits sorted by NC score

PDK4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	O70571	Gene names	Pdk4
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4).

PDK4_HUMAN
NC score	0.999577 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	Q16654	Gene names	PDK4
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4).

PDK2_HUMAN
NC score	0.996507 (rank : 3)	θ value	2.76339e-158 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q15119, Q9BS05	Gene names	PDK2
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2).

PDK2_MOUSE
NC score	0.996499 (rank : 4)	θ value	1.62005e-158 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JK42	Gene names	Pdk2
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2).

PDK1_HUMAN
NC score	0.996415 (rank : 5)	θ value	2.95243e-160 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q15118	Gene names	PDK1
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1).

PDK1_MOUSE
NC score	0.995883 (rank : 6)	θ value	1.37145e-157 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BFP9	Gene names	Pdk1
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1).

PDK3_HUMAN
NC score	0.994851 (rank : 7)	θ value	1.37464e-149 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q15120	Gene names	PDK3
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3).

PDK3_MOUSE
NC score	0.994801 (rank : 8)	θ value	4.72459e-150 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q922H2, Q8BTX1	Gene names	Pdk3
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3).

BCKD_HUMAN
NC score	0.877842 (rank : 9)	θ value	3.16345e-37 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	O14874, Q96IN5	Gene names	BCKDK
Domain Architecture
Description	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKDHKIN) (BCKD-kinase).

BCKD_MOUSE
NC score	0.876922 (rank : 10)	θ value	9.20422e-37 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	O55028	Gene names	Bckdk
Domain Architecture
Description	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKDHKIN) (BCKD-kinase).

SPT6H_MOUSE
NC score	0.017280 (rank : 11)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

CT128_HUMAN
NC score	0.015988 (rank : 12)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BQN1, Q5JWN6, Q8N276	Gene names	C20orf128
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf128.

SPT6H_HUMAN
NC score	0.015912 (rank : 13)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

CCD22_MOUSE
NC score	0.008581 (rank : 14)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	268	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JIG7, Q8BYH4	Gene names	Ccdc22, DXImx40e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

TCF20_MOUSE
NC score	0.006293 (rank : 15)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	396	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

ATRX_HUMAN
NC score	0.005949 (rank : 16)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	842	Shared Neighborhood Hits	2
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

M3K4_MOUSE
NC score	-0.000556 (rank : 17)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	924	Shared Neighborhood Hits	3
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

M3K4_HUMAN
NC score	-0.000730 (rank : 18)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	911	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).