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Network neighborhood for query Sequence : PDK1_MOUSE

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PDK1_MOUSE
SwissProt Accessions	Q8BFP9	Gene names	Pdk1
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PDK1_HUMAN
θ value	0 (rank : 1)	NC score	0.999787 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q15118	Gene names	PDK1
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1).

PDK1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BFP9	Gene names	Pdk1
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1).

PDK2_HUMAN
θ value	5.55514e-167 (rank : 3)	NC score	0.997236 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	Q15119, Q9BS05	Gene names	PDK2
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2).

PDK2_MOUSE
θ value	1.04765e-165 (rank : 4)	NC score	0.997092 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JK42	Gene names	Pdk2
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2).

PDK3_MOUSE
θ value	1.28067e-163 (rank : 5)	NC score	0.996096 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q922H2, Q8BTX1	Gene names	Pdk3
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3).

PDK3_HUMAN
θ value	4.11978e-162 (rank : 6)	NC score	0.996091 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q15120	Gene names	PDK3
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3).

PDK4_MOUSE
θ value	1.37145e-157 (rank : 7)	NC score	0.995883 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	O70571	Gene names	Pdk4
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4).

PDK4_HUMAN
θ value	1.28364e-155 (rank : 8)	NC score	0.995968 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	Q16654	Gene names	PDK4
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4).

BCKD_HUMAN
θ value	5.21438e-40 (rank : 9)	NC score	0.881236 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	O14874, Q96IN5	Gene names	BCKDK
Domain Architecture
Description	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKDHKIN) (BCKD-kinase).

BCKD_MOUSE
θ value	1.51715e-39 (rank : 10)	NC score	0.880329 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	O55028	Gene names	Bckdk
Domain Architecture
Description	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKDHKIN) (BCKD-kinase).

EXOC6_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.017046 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TAG9, Q9NZ24	Gene names	EXOC6, SEC15A, SEC15L, SEC15L1
Domain Architecture
Description	Exocyst complex component 6 (Exocyst complex component Sec15A) (Sec15- like 1).

AL2SF_HUMAN
θ value	1.81305 (rank : 12)	NC score	0.057282 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	6	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZP36, Q8N8R4, Q96Q31	Gene names	ALS2CR16
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein.

UQCR2_MOUSE
θ value	1.81305 (rank : 13)	NC score	0.022770 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DB77	Gene names	Uqcrc2
Domain Architecture
Description	Ubiquinol-cytochrome-c reductase complex core protein 2, mitochondrial precursor (EC 1.10.2.2) (Complex III subunit II).

DDX17_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.004368 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

Hits sorted by NC score

PDK1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BFP9	Gene names	Pdk1
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1).

PDK1_HUMAN
NC score	0.999787 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q15118	Gene names	PDK1
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1).

PDK2_HUMAN
NC score	0.997236 (rank : 3)	θ value	5.55514e-167 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	11
SwissProt Accessions	Q15119, Q9BS05	Gene names	PDK2
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2).

PDK2_MOUSE
NC score	0.997092 (rank : 4)	θ value	1.04765e-165 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JK42	Gene names	Pdk2
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2).

PDK3_MOUSE
NC score	0.996096 (rank : 5)	θ value	1.28067e-163 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q922H2, Q8BTX1	Gene names	Pdk3
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3).

PDK3_HUMAN
NC score	0.996091 (rank : 6)	θ value	4.11978e-162 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q15120	Gene names	PDK3
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3).

PDK4_HUMAN
NC score	0.995968 (rank : 7)	θ value	1.28364e-155 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	Q16654	Gene names	PDK4
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4).

PDK4_MOUSE
NC score	0.995883 (rank : 8)	θ value	1.37145e-157 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	O70571	Gene names	Pdk4
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4).

BCKD_HUMAN
NC score	0.881236 (rank : 9)	θ value	5.21438e-40 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	O14874, Q96IN5	Gene names	BCKDK
Domain Architecture
Description	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKDHKIN) (BCKD-kinase).

BCKD_MOUSE
NC score	0.880329 (rank : 10)	θ value	1.51715e-39 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	O55028	Gene names	Bckdk
Domain Architecture
Description	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKDHKIN) (BCKD-kinase).

AL2SF_HUMAN
NC score	0.057282 (rank : 11)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	6	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZP36, Q8N8R4, Q96Q31	Gene names	ALS2CR16
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein.

UQCR2_MOUSE
NC score	0.022770 (rank : 12)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DB77	Gene names	Uqcrc2
Domain Architecture
Description	Ubiquinol-cytochrome-c reductase complex core protein 2, mitochondrial precursor (EC 1.10.2.2) (Complex III subunit II).

EXOC6_HUMAN
NC score	0.017046 (rank : 13)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TAG9, Q9NZ24	Gene names	EXOC6, SEC15A, SEC15L, SEC15L1
Domain Architecture
Description	Exocyst complex component 6 (Exocyst complex component Sec15A) (Sec15- like 1).

DDX17_MOUSE
NC score	0.004368 (rank : 14)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).