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Network neighborhood for query Sequence : PDK3_MOUSE

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PDK3_MOUSE
SwissProt Accessions	Q922H2, Q8BTX1	Gene names	Pdk3
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PDK3_HUMAN
θ value	0 (rank : 1)	NC score	0.999856 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	16
SwissProt Accessions	Q15120	Gene names	PDK3
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3).

PDK3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q922H2, Q8BTX1	Gene names	Pdk3
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3).

PDK1_HUMAN
θ value	9.80574e-164 (rank : 3)	NC score	0.996455 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q15118	Gene names	PDK1
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1).

PDK1_MOUSE
θ value	1.28067e-163 (rank : 4)	NC score	0.996096 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BFP9	Gene names	Pdk1
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1).

PDK2_HUMAN
θ value	8.30107e-163 (rank : 5)	NC score	0.996611 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q15119, Q9BS05	Gene names	PDK2
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2).

PDK2_MOUSE
θ value	1.84928e-162 (rank : 6)	NC score	0.996555 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JK42	Gene names	Pdk2
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2).

PDK4_MOUSE
θ value	4.72459e-150 (rank : 7)	NC score	0.994801 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	O70571	Gene names	Pdk4
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4).

PDK4_HUMAN
θ value	4.42207e-148 (rank : 8)	NC score	0.994841 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	Q16654	Gene names	PDK4
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4).

BCKD_HUMAN
θ value	2.67802e-36 (rank : 9)	NC score	0.875066 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	O14874, Q96IN5	Gene names	BCKDK
Domain Architecture
Description	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKDHKIN) (BCKD-kinase).

BCKD_MOUSE
θ value	7.79185e-36 (rank : 10)	NC score	0.874117 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	O55028	Gene names	Bckdk
Domain Architecture
Description	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKDHKIN) (BCKD-kinase).

ZHX3_MOUSE
θ value	1.06291 (rank : 11)	NC score	0.018254 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	321	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0Q2, Q80U14	Gene names	Zhx3, Kiaa0395, Tix1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

ANXA2_HUMAN
θ value	4.03905 (rank : 12)	NC score	0.011173 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	P07355, Q96DD5	Gene names	ANXA2, ANX2
Domain Architecture
Description	Annexin A2 (Annexin II) (Lipocortin II) (Calpactin I heavy chain) (Chromobindin-8) (p36) (Protein I) (Placental anticoagulant protein IV) (PAP-IV).

ANXA2_MOUSE
θ value	4.03905 (rank : 13)	NC score	0.011217 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	P07356	Gene names	Anxa2, Anx2, Cal1h
Domain Architecture
Description	Annexin A2 (Annexin II) (Lipocortin II) (Calpactin I heavy chain) (Chromobindin-8) (p36) (Protein I) (Placental anticoagulant protein IV) (PAP-IV).

MMP13_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.006108 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	P45452	Gene names	MMP13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

BIEA_MOUSE
θ value	8.99809 (rank : 15)	NC score	0.016267 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CY64, Q3T9C6, Q80WR6, Q9DD21	Gene names	Blvra
Domain Architecture
Description	Biliverdin reductase A precursor (EC 1.3.1.24) (Biliverdin-IX alpha- reductase) (BVR A).

FARP2_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.001880 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	240	Shared Neighborhood Hits	2
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

TCF20_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.007859 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	323	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

Hits sorted by NC score

PDK3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q922H2, Q8BTX1	Gene names	Pdk3
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3).

PDK3_HUMAN
NC score	0.999856 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	16
SwissProt Accessions	Q15120	Gene names	PDK3
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3).

PDK2_HUMAN
NC score	0.996611 (rank : 3)	θ value	8.30107e-163 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q15119, Q9BS05	Gene names	PDK2
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2).

PDK2_MOUSE
NC score	0.996555 (rank : 4)	θ value	1.84928e-162 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JK42	Gene names	Pdk2
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2).

PDK1_HUMAN
NC score	0.996455 (rank : 5)	θ value	9.80574e-164 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q15118	Gene names	PDK1
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1).

PDK1_MOUSE
NC score	0.996096 (rank : 6)	θ value	1.28067e-163 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BFP9	Gene names	Pdk1
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1).

PDK4_HUMAN
NC score	0.994841 (rank : 7)	θ value	4.42207e-148 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	Q16654	Gene names	PDK4
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4).

PDK4_MOUSE
NC score	0.994801 (rank : 8)	θ value	4.72459e-150 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	O70571	Gene names	Pdk4
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial precursor (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4).

BCKD_HUMAN
NC score	0.875066 (rank : 9)	θ value	2.67802e-36 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	O14874, Q96IN5	Gene names	BCKDK
Domain Architecture
Description	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKDHKIN) (BCKD-kinase).

BCKD_MOUSE
NC score	0.874117 (rank : 10)	θ value	7.79185e-36 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	O55028	Gene names	Bckdk
Domain Architecture
Description	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKDHKIN) (BCKD-kinase).

ZHX3_MOUSE
NC score	0.018254 (rank : 11)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	321	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0Q2, Q80U14	Gene names	Zhx3, Kiaa0395, Tix1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

BIEA_MOUSE
NC score	0.016267 (rank : 12)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CY64, Q3T9C6, Q80WR6, Q9DD21	Gene names	Blvra
Domain Architecture
Description	Biliverdin reductase A precursor (EC 1.3.1.24) (Biliverdin-IX alpha- reductase) (BVR A).

ANXA2_MOUSE
NC score	0.011217 (rank : 13)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	P07356	Gene names	Anxa2, Anx2, Cal1h
Domain Architecture
Description	Annexin A2 (Annexin II) (Lipocortin II) (Calpactin I heavy chain) (Chromobindin-8) (p36) (Protein I) (Placental anticoagulant protein IV) (PAP-IV).

ANXA2_HUMAN
NC score	0.011173 (rank : 14)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	P07355, Q96DD5	Gene names	ANXA2, ANX2
Domain Architecture
Description	Annexin A2 (Annexin II) (Lipocortin II) (Calpactin I heavy chain) (Chromobindin-8) (p36) (Protein I) (Placental anticoagulant protein IV) (PAP-IV).

TCF20_HUMAN
NC score	0.007859 (rank : 15)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	323	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

MMP13_HUMAN
NC score	0.006108 (rank : 16)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	P45452	Gene names	MMP13
Domain Architecture
Description	Collagenase 3 precursor (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13).

FARP2_HUMAN
NC score	0.001880 (rank : 17)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	240	Shared Neighborhood Hits	2
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).