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Network neighborhood for query Sequence : MIS_MOUSE

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MIS_MOUSE
SwissProt Accessions	P27106	Gene names	Amh
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MIS_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	86	Target Neighborhood Hits	86	Shared Neighborhood Hits	86
SwissProt Accessions	P27106	Gene names	Amh
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

MIS_HUMAN
θ value	4.53388e-177 (rank : 2)	NC score	0.962713 (rank : 2)
Query Neighborhood Hits	86	Target Neighborhood Hits	87	Shared Neighborhood Hits	61
SwissProt Accessions	P03971, O75246	Gene names	AMH, MIF
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

GDF1_MOUSE
θ value	1.06045e-08 (rank : 3)	NC score	0.596224 (rank : 3)
Query Neighborhood Hits	86	Target Neighborhood Hits	71	Shared Neighborhood Hits	58
SwissProt Accessions	P20863	Gene names	Gdf1, Gdf-1
Domain Architecture
Description	Embryonic growth/differentiation factor 1 precursor (GDF-1).

GDF1_HUMAN
θ value	1.80886e-08 (rank : 4)	NC score	0.588581 (rank : 4)
Query Neighborhood Hits	86	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	P27539, O43344	Gene names	GDF1
Domain Architecture
Description	Embryonic growth/differentiation factor 1 precursor (GDF-1).

INHBC_MOUSE
θ value	8.40245e-06 (rank : 5)	NC score	0.554260 (rank : 7)
Query Neighborhood Hits	86	Target Neighborhood Hits	65	Shared Neighborhood Hits	57
SwissProt Accessions	P55104, Q61452	Gene names	Inhbc
Domain Architecture
Description	Inhibin beta C chain precursor (Activin beta-C chain).

GDF11_HUMAN
θ value	1.43324e-05 (rank : 6)	NC score	0.557302 (rank : 6)
Query Neighborhood Hits	86	Target Neighborhood Hits	73	Shared Neighborhood Hits	58
SwissProt Accessions	O95390, Q9UID1, Q9UID2	Gene names	GDF11, BMP11
Domain Architecture
Description	Growth/differentiation factor 11 precursor (GDF-11) (Bone morphogenetic protein 11).

GDF11_MOUSE
θ value	1.43324e-05 (rank : 7)	NC score	0.557531 (rank : 5)
Query Neighborhood Hits	86	Target Neighborhood Hits	73	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z1W4, Q9QX55, Q9R221	Gene names	Gdf11, Bmp11
Domain Architecture
Description	Growth/differentiation factor 11 precursor (GDF-11) (Bone morphogenetic protein 11).

BMP3_MOUSE
θ value	2.44474e-05 (rank : 8)	NC score	0.524146 (rank : 26)
Query Neighborhood Hits	86	Target Neighborhood Hits	82	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BHE5	Gene names	Bmp3
Domain Architecture	No domain graphic available
Description	Bone morphogenetic protein 3 precursor (BMP-3).

BMP3_HUMAN
θ value	3.19293e-05 (rank : 9)	NC score	0.521340 (rank : 28)
Query Neighborhood Hits	86	Target Neighborhood Hits	85	Shared Neighborhood Hits	56
SwissProt Accessions	P12645	Gene names	BMP3
Domain Architecture
Description	Bone morphogenetic protein 3 precursor (BMP-3) (Osteogenin) (BMP-3A).

BMP2_HUMAN
θ value	7.1131e-05 (rank : 10)	NC score	0.535058 (rank : 18)
Query Neighborhood Hits	86	Target Neighborhood Hits	74	Shared Neighborhood Hits	57
SwissProt Accessions	P12643	Gene names	BMP2, BMP2A
Domain Architecture
Description	Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A).

BMP2_MOUSE
θ value	7.1131e-05 (rank : 11)	NC score	0.535078 (rank : 17)
Query Neighborhood Hits	86	Target Neighborhood Hits	76	Shared Neighborhood Hits	57
SwissProt Accessions	P21274	Gene names	Bmp2, Bmp-2
Domain Architecture
Description	Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A).

BMP3B_MOUSE
θ value	7.1131e-05 (rank : 12)	NC score	0.516688 (rank : 35)
Query Neighborhood Hits	86	Target Neighborhood Hits	80	Shared Neighborhood Hits	56
SwissProt Accessions	P97737	Gene names	Gdf10, Bmp3b
Domain Architecture
Description	Bone morphogenetic protein 3b precursor (BMP-3b) (Growth/differentiation factor 10) (GDF-10).

GDF8_HUMAN
θ value	7.1131e-05 (rank : 13)	NC score	0.551508 (rank : 9)
Query Neighborhood Hits	86	Target Neighborhood Hits	71	Shared Neighborhood Hits	58
SwissProt Accessions	O14793, Q6B0H2	Gene names	GDF8, MSTN
Domain Architecture
Description	Growth/differentiation factor 8 precursor (GDF-8) (Myostatin).

GDF8_MOUSE
θ value	7.1131e-05 (rank : 14)	NC score	0.551530 (rank : 8)
Query Neighborhood Hits	86	Target Neighborhood Hits	71	Shared Neighborhood Hits	58
SwissProt Accessions	O08689	Gene names	Gdf8, Mstn
Domain Architecture
Description	Growth/differentiation factor 8 precursor (GDF-8) (Myostatin).

BMP4_MOUSE
θ value	9.29e-05 (rank : 15)	NC score	0.531610 (rank : 23)
Query Neighborhood Hits	86	Target Neighborhood Hits	71	Shared Neighborhood Hits	58
SwissProt Accessions	P21275	Gene names	Bmp4, Bmp-4, Dvr-4
Domain Architecture
Description	Bone morphogenetic protein 4 precursor (BMP-4) (BMP-2B).

NODAL_HUMAN
θ value	0.000121331 (rank : 16)	NC score	0.531856 (rank : 21)
Query Neighborhood Hits	86	Target Neighborhood Hits	66	Shared Neighborhood Hits	57
SwissProt Accessions	Q96S42, Q2M3A5, Q8N4V3	Gene names	NODAL
Domain Architecture
Description	Nodal homolog precursor.

PSPN_MOUSE
θ value	0.000121331 (rank : 17)	NC score	0.245208 (rank : 62)
Query Neighborhood Hits	86	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	O70300	Gene names	Pspn
Domain Architecture
Description	Persephin precursor (PSP).

BMP3B_HUMAN
θ value	0.000158464 (rank : 18)	NC score	0.515574 (rank : 36)
Query Neighborhood Hits	86	Target Neighborhood Hits	90	Shared Neighborhood Hits	57
SwissProt Accessions	P55107, Q9UCX6	Gene names	GDF10, BMP3B
Domain Architecture
Description	Bone morphogenetic protein 3b precursor (BMP-3b) (Growth/differentiation factor 10) (GDF-10) (Bone-inducing protein) (BIP).

BMP4_HUMAN
θ value	0.000158464 (rank : 19)	NC score	0.531538 (rank : 24)
Query Neighborhood Hits	86	Target Neighborhood Hits	72	Shared Neighborhood Hits	59
SwissProt Accessions	P12644, Q9UM80	Gene names	BMP4, BMP2B, DVR4
Domain Architecture
Description	Bone morphogenetic protein 4 precursor (BMP-4) (BMP-2B).

GDF7_MOUSE
θ value	0.000158464 (rank : 20)	NC score	0.547927 (rank : 11)
Query Neighborhood Hits	86	Target Neighborhood Hits	70	Shared Neighborhood Hits	57
SwissProt Accessions	P43029, Q7TNX4, Q99MY1	Gene names	Gdf7, Gdf-7
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 7 precursor (GDF-7).

GDF15_HUMAN
θ value	0.00020696 (rank : 21)	NC score	0.525764 (rank : 25)
Query Neighborhood Hits	86	Target Neighborhood Hits	68	Shared Neighborhood Hits	59
SwissProt Accessions	Q99988, O14629, P78360, Q9NRT0	Gene names	GDF15, MIC1, PDF, PLAB, PTGFB
Domain Architecture
Description	Growth/differentiation factor 15 precursor (GDF-15) (Placental bone morphogenetic protein) (Placental TGF-beta) (Macrophage inhibitory cytokine 1) (MIC-1) (Prostate differentiation factor) (NSAID-regulated protein 1) (NRG-1).

GDF5_HUMAN
θ value	0.000270298 (rank : 22)	NC score	0.536088 (rank : 15)
Query Neighborhood Hits	86	Target Neighborhood Hits	103	Shared Neighborhood Hits	57
SwissProt Accessions	P43026, Q96SB1	Gene names	GDF5, CDMP1
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Radotermin).

GDF5_MOUSE
θ value	0.000270298 (rank : 23)	NC score	0.535848 (rank : 16)
Query Neighborhood Hits	86	Target Neighborhood Hits	99	Shared Neighborhood Hits	57
SwissProt Accessions	P43027	Gene names	Gdf5, Bp, Gdf-5
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5).

GDF7_HUMAN
θ value	0.000270298 (rank : 24)	NC score	0.546285 (rank : 13)
Query Neighborhood Hits	86	Target Neighborhood Hits	66	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z4P5	Gene names	GDF7
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 7 precursor (GDF-7).

INHBB_HUMAN
θ value	0.00035302 (rank : 25)	NC score	0.542157 (rank : 14)
Query Neighborhood Hits	86	Target Neighborhood Hits	70	Shared Neighborhood Hits	58
SwissProt Accessions	P09529, Q8N1D3	Gene names	INHBB
Domain Architecture
Description	Inhibin beta B chain precursor (Activin beta-B chain).

INHBE_MOUSE
θ value	0.00102713 (rank : 26)	NC score	0.548298 (rank : 10)
Query Neighborhood Hits	86	Target Neighborhood Hits	69	Shared Neighborhood Hits	57
SwissProt Accessions	O08717	Gene names	Inhbe
Domain Architecture
Description	Inhibin beta E chain precursor (Activin beta-E chain).

BMP10_MOUSE
θ value	0.00134147 (rank : 27)	NC score	0.520791 (rank : 29)
Query Neighborhood Hits	86	Target Neighborhood Hits	75	Shared Neighborhood Hits	57
SwissProt Accessions	Q9R229, Q9Z1V8	Gene names	Bmp10
Domain Architecture
Description	Bone morphogenetic protein 10 precursor (BMP-10).

INHBE_HUMAN
θ value	0.00175202 (rank : 28)	NC score	0.546497 (rank : 12)
Query Neighborhood Hits	86	Target Neighborhood Hits	69	Shared Neighborhood Hits	57
SwissProt Accessions	P58166	Gene names	INHBE
Domain Architecture
Description	Inhibin beta E chain precursor (Activin beta-E chain).

TGFB1_MOUSE
θ value	0.00175202 (rank : 29)	NC score	0.494466 (rank : 48)
Query Neighborhood Hits	86	Target Neighborhood Hits	64	Shared Neighborhood Hits	57
SwissProt Accessions	P04202	Gene names	Tgfb1
Domain Architecture
Description	Transforming growth factor beta-1 precursor (TGF-beta-1) [Contains: Latency-associated peptide (LAP)].

TGFB1_HUMAN
θ value	0.00228821 (rank : 30)	NC score	0.495653 (rank : 45)
Query Neighborhood Hits	86	Target Neighborhood Hits	64	Shared Neighborhood Hits	57
SwissProt Accessions	P01137, Q9UCG4	Gene names	TGFB1, TGFB
Domain Architecture
Description	Transforming growth factor beta-1 precursor (TGF-beta-1) [Contains: Latency-associated peptide (LAP)].

BMP6_HUMAN
θ value	0.00298849 (rank : 31)	NC score	0.508724 (rank : 39)
Query Neighborhood Hits	86	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	P22004	Gene names	BMP6, VGR
Domain Architecture
Description	Bone morphogenetic protein 6 precursor (BMP-6).

BMP6_MOUSE
θ value	0.00298849 (rank : 32)	NC score	0.507484 (rank : 41)
Query Neighborhood Hits	86	Target Neighborhood Hits	84	Shared Neighborhood Hits	59
SwissProt Accessions	P20722	Gene names	Bmp6, Bmp-6, Vgr1
Domain Architecture
Description	Bone morphogenetic protein 6 precursor (BMP-6) (VG-1-related protein) (VGR-1).

BMP10_HUMAN
θ value	0.00390308 (rank : 33)	NC score	0.520251 (rank : 32)
Query Neighborhood Hits	86	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	O95393	Gene names	BMP10
Domain Architecture
Description	Bone morphogenetic protein 10 precursor (BMP-10).

GDF2_HUMAN
θ value	0.00390308 (rank : 34)	NC score	0.517347 (rank : 33)
Query Neighborhood Hits	86	Target Neighborhood Hits	77	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UK05, Q9Y571	Gene names	GDF2, BMP9
Domain Architecture
Description	Growth/differentiation factor 2 precursor (GDF-2) (Bone morphogenetic protein 9) (BMP-9).

GDF6_HUMAN
θ value	0.00390308 (rank : 35)	NC score	0.533456 (rank : 20)
Query Neighborhood Hits	86	Target Neighborhood Hits	76	Shared Neighborhood Hits	57
SwissProt Accessions	Q6KF10, Q6PI58	Gene names	GDF6, GDF16
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 6 precursor (GDF-6) (Growth/differentiation factor 16).

GDF6_MOUSE
θ value	0.00390308 (rank : 36)	NC score	0.533561 (rank : 19)
Query Neighborhood Hits	86	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	P43028, Q70UT4	Gene names	Gdf6, Gdf-6, Gdf16
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 6 precursor (GDF-6) (Growth/differentiation factor 16).

BMP7_HUMAN
θ value	0.00509761 (rank : 37)	NC score	0.499592 (rank : 42)
Query Neighborhood Hits	86	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	P18075, Q9H512, Q9NTQ7	Gene names	BMP7, OP1
Domain Architecture
Description	Bone morphogenetic protein 7 precursor (BMP-7) (Osteogenic protein 1) (OP-1) (Eptotermin alfa).

INHBC_HUMAN
θ value	0.00509761 (rank : 38)	NC score	0.531673 (rank : 22)
Query Neighborhood Hits	86	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	P55103	Gene names	INHBC
Domain Architecture
Description	Inhibin beta C chain precursor (Activin beta-C chain).

BMP7_MOUSE
θ value	0.00665767 (rank : 39)	NC score	0.498700 (rank : 43)
Query Neighborhood Hits	86	Target Neighborhood Hits	65	Shared Neighborhood Hits	57
SwissProt Accessions	P23359, Q91XF7	Gene names	Bmp7, Bmp-7, Op1
Domain Architecture
Description	Bone morphogenetic protein 7 precursor (BMP-7) (Osteogenic protein 1) (OP-1).

NODAL_MOUSE
θ value	0.00869519 (rank : 40)	NC score	0.523561 (rank : 27)
Query Neighborhood Hits	86	Target Neighborhood Hits	66	Shared Neighborhood Hits	57
SwissProt Accessions	P43021	Gene names	Nodal
Domain Architecture
Description	Nodal precursor.

GDF2_MOUSE
θ value	0.0148317 (rank : 41)	NC score	0.515171 (rank : 37)
Query Neighborhood Hits	86	Target Neighborhood Hits	70	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WV56, Q9QZE0	Gene names	Gdf2, Bmp9
Domain Architecture
Description	Growth/differentiation factor 2 precursor (GDF-2) (Bone morphogenetic protein 9) (BMP-9).

INHBA_HUMAN
θ value	0.0148317 (rank : 42)	NC score	0.520710 (rank : 30)
Query Neighborhood Hits	86	Target Neighborhood Hits	75	Shared Neighborhood Hits	57
SwissProt Accessions	P08476, Q14599	Gene names	INHBA
Domain Architecture
Description	Inhibin beta A chain precursor (Activin beta-A chain) (Erythroid differentiation protein) (EDF).

INHBA_MOUSE
θ value	0.0148317 (rank : 43)	NC score	0.520466 (rank : 31)
Query Neighborhood Hits	86	Target Neighborhood Hits	75	Shared Neighborhood Hits	57
SwissProt Accessions	Q04998	Gene names	Inhba
Domain Architecture
Description	Inhibin beta A chain precursor (Activin beta-A chain).

TGFB3_HUMAN
θ value	0.0148317 (rank : 44)	NC score	0.485024 (rank : 52)
Query Neighborhood Hits	86	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	P10600	Gene names	TGFB3
Domain Architecture
Description	Transforming growth factor beta-3 precursor (TGF-beta-3).

TGFB2_MOUSE
θ value	0.0193708 (rank : 45)	NC score	0.477832 (rank : 54)
Query Neighborhood Hits	86	Target Neighborhood Hits	70	Shared Neighborhood Hits	57
SwissProt Accessions	P27090	Gene names	Tgfb2
Domain Architecture
Description	Transforming growth factor beta-2 precursor (TGF-beta-2).

BMP8A_MOUSE
θ value	0.0252991 (rank : 46)	NC score	0.496657 (rank : 44)
Query Neighborhood Hits	86	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	P34821	Gene names	Bmp8a, Bmp-8, Bmp8
Domain Architecture
Description	Bone morphogenetic protein 8A precursor (BMP-8A) (Osteogenic protein 2) (OP-2).

BMP5_HUMAN
θ value	0.0330416 (rank : 47)	NC score	0.495204 (rank : 46)
Query Neighborhood Hits	86	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	P22003, Q9H547, Q9NTM5	Gene names	BMP5
Domain Architecture
Description	Bone morphogenetic protein 5 precursor (BMP-5).

BMP5_MOUSE
θ value	0.0330416 (rank : 48)	NC score	0.494616 (rank : 47)
Query Neighborhood Hits	86	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	P49003	Gene names	Bmp5, Bmp-5
Domain Architecture
Description	Bone morphogenetic protein 5 precursor (BMP-5).

TGFB3_MOUSE
θ value	0.0330416 (rank : 49)	NC score	0.483019 (rank : 53)
Query Neighborhood Hits	86	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	P17125	Gene names	Tgfb3
Domain Architecture
Description	Transforming growth factor beta-3 precursor (TGF-beta-3).

BMP8A_HUMAN
θ value	0.0431538 (rank : 50)	NC score	0.494347 (rank : 49)
Query Neighborhood Hits	86	Target Neighborhood Hits	66	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z5Y6, Q5T3A5	Gene names	BMP8A
Domain Architecture	No domain graphic available
Description	Bone morphogenetic protein 8A precursor (BMP-8A).

BMP8B_MOUSE
θ value	0.0431538 (rank : 51)	NC score	0.489529 (rank : 51)
Query Neighborhood Hits	86	Target Neighborhood Hits	70	Shared Neighborhood Hits	57
SwissProt Accessions	P55105	Gene names	Bmp8b
Domain Architecture
Description	Bone morphogenetic protein 8B precursor (BMP-8B).

TGFB2_HUMAN
θ value	0.0431538 (rank : 52)	NC score	0.474729 (rank : 55)
Query Neighborhood Hits	86	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	P61812, P08112, Q15579, Q15581, Q4VAV9	Gene names	TGFB2
Domain Architecture
Description	Transforming growth factor beta-2 precursor (TGF-beta-2) (Glioblastoma-derived T-cell suppressor factor) (G-TSF) (BSC-1 cell growth inhibitor) (Polyergin) (Cetermin).

GDF15_MOUSE
θ value	0.0563607 (rank : 53)	NC score	0.516973 (rank : 34)
Query Neighborhood Hits	86	Target Neighborhood Hits	71	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z0J7	Gene names	Gdf15, Sbf
Domain Architecture
Description	Growth/differentiation factor 15 precursor (GDF-15).

BMP8B_HUMAN
θ value	0.0961366 (rank : 54)	NC score	0.492037 (rank : 50)
Query Neighborhood Hits	86	Target Neighborhood Hits	65	Shared Neighborhood Hits	57
SwissProt Accessions	P34820, Q53ZM7, Q9NUF0	Gene names	BMP8B, BMP8
Domain Architecture
Description	Bone morphogenetic protein 8B precursor (BMP-8B) (BMP-8) (Osteogenic protein 2) (OP-2).

GDF3_MOUSE
θ value	0.163984 (rank : 55)	NC score	0.513323 (rank : 38)
Query Neighborhood Hits	86	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	Q07104	Gene names	Gdf3, Gdf-3, Vgr-2
Domain Architecture
Description	Growth/differentiation factor 3 precursor (GDF-3) (VG-1-related protein 2).

ARTN_MOUSE
θ value	0.279714 (rank : 56)	NC score	0.104758 (rank : 70)
Query Neighborhood Hits	86	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z0L2, Q3SXF4, Q3SXF5	Gene names	Artn
Domain Architecture	No domain graphic available
Description	Artemin precursor.

NRTN_HUMAN
θ value	0.279714 (rank : 57)	NC score	0.163325 (rank : 67)
Query Neighborhood Hits	86	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q99748	Gene names	NRTN
Domain Architecture
Description	Neurturin precursor.

GSCR1_HUMAN
θ value	0.365318 (rank : 58)	NC score	0.039607 (rank : 74)
Query Neighborhood Hits	86	Target Neighborhood Hits	674	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

DGKK_HUMAN
θ value	0.47712 (rank : 59)	NC score	0.038596 (rank : 75)
Query Neighborhood Hits	86	Target Neighborhood Hits	378	Shared Neighborhood Hits	5
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

GDF3_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.507915 (rank : 40)
Query Neighborhood Hits	86	Target Neighborhood Hits	65	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NR23, Q8NEJ4	Gene names	GDF3
Domain Architecture
Description	Growth/differentiation factor 3 precursor (GDF-3).

MLL3_MOUSE
θ value	1.06291 (rank : 61)	NC score	0.024322 (rank : 87)
Query Neighborhood Hits	86	Target Neighborhood Hits	1399	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NRTN_MOUSE
θ value	1.06291 (rank : 62)	NC score	0.126758 (rank : 68)
Query Neighborhood Hits	86	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	P97463	Gene names	Nrtn
Domain Architecture
Description	Neurturin precursor.

PTN18_MOUSE
θ value	1.06291 (rank : 63)	NC score	0.011543 (rank : 94)
Query Neighborhood Hits	86	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

SETD2_HUMAN
θ value	1.06291 (rank : 64)	NC score	0.029018 (rank : 80)
Query Neighborhood Hits	86	Target Neighborhood Hits	412	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

HCFC1_HUMAN
θ value	1.38821 (rank : 65)	NC score	0.028706 (rank : 81)
Query Neighborhood Hits	86	Target Neighborhood Hits	331	Shared Neighborhood Hits	5
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

MOT8_MOUSE
θ value	1.81305 (rank : 66)	NC score	0.021240 (rank : 88)
Query Neighborhood Hits	86	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	O70324, Q8K3S9	Gene names	Slc16a2, Mct8, Xpct
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

PHLA1_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.034725 (rank : 76)
Query Neighborhood Hits	86	Target Neighborhood Hits	121	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

BAZ2A_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.017700 (rank : 90)
Query Neighborhood Hits	86	Target Neighborhood Hits	780	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

GGN_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.025188 (rank : 83)
Query Neighborhood Hits	86	Target Neighborhood Hits	269	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

LEFTB_HUMAN
θ value	2.36792 (rank : 70)	NC score	0.240771 (rank : 63)
Query Neighborhood Hits	86	Target Neighborhood Hits	63	Shared Neighborhood Hits	55
SwissProt Accessions	O75610	Gene names	LEFTB, LEFTYB
Domain Architecture
Description	Left-right determination factor B precursor (Lefty-B protein).

WASF1_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.034425 (rank : 77)
Query Neighborhood Hits	86	Target Neighborhood Hits	260	Shared Neighborhood Hits	7
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

BMP15_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.454567 (rank : 56)
Query Neighborhood Hits	86	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	O95972, Q5JST1, Q9UMS1	Gene names	BMP15, GDF9B
Domain Architecture
Description	Bone morphogenetic protein 15 precursor (BMP-15) (Growth/differentiation factor 9B) (GDF-9B).

TPSN_MOUSE
θ value	3.0926 (rank : 73)	NC score	0.027091 (rank : 82)
Query Neighborhood Hits	86	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R233, O70317, Q91YE0, Q91YE1, Q9QWT7, Q9Z1W3	Gene names	Tapbp, Tapa
Domain Architecture
Description	Tapasin precursor (TPSN) (TPN) (TAP-binding protein) (TAP-associated protein).

BRD4_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.011644 (rank : 93)
Query Neighborhood Hits	86	Target Neighborhood Hits	851	Shared Neighborhood Hits	9
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

EPM2A_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.029607 (rank : 79)
Query Neighborhood Hits	86	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WUA5, Q8BY80	Gene names	Epm2a
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

PRDM2_HUMAN
θ value	4.03905 (rank : 76)	NC score	0.002102 (rank : 96)
Query Neighborhood Hits	86	Target Neighborhood Hits	1135	Shared Neighborhood Hits	5
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

TITIN_HUMAN
θ value	4.03905 (rank : 77)	NC score	-0.002214 (rank : 97)
Query Neighborhood Hits	86	Target Neighborhood Hits	2923	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

WASF1_MOUSE
θ value	4.03905 (rank : 78)	NC score	0.030248 (rank : 78)
Query Neighborhood Hits	86	Target Neighborhood Hits	261	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

ALEX_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.019400 (rank : 89)
Query Neighborhood Hits	86	Target Neighborhood Hits	361	Shared Neighborhood Hits	7
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ARTN_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.126086 (rank : 69)
Query Neighborhood Hits	86	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T4W7, O95441, O96030, Q6P6A3	Gene names	ARTN, EVN
Domain Architecture	No domain graphic available
Description	Artemin precursor (Enovin) (Neublastin).

HCFC1_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.024447 (rank : 86)
Query Neighborhood Hits	86	Target Neighborhood Hits	348	Shared Neighborhood Hits	6
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

ASPC1_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.016762 (rank : 91)
Query Neighborhood Hits	86	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VBT9, Q3UKD1, Q6V7K5, Q9CT64	Gene names	Aspscr1, Tug
Domain Architecture	No domain graphic available
Description	Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosome region candidate 1 homolog).

EPM2A_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.024583 (rank : 85)
Query Neighborhood Hits	86	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	O95278, O95483, Q8IU96, Q8IX24, Q8IX25, Q9BS66, Q9UEN2	Gene names	EPM2A
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

GNDS_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.013628 (rank : 92)
Query Neighborhood Hits	86	Target Neighborhood Hits	201	Shared Neighborhood Hits	6
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

PHLA1_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.024583 (rank : 84)
Query Neighborhood Hits	86	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	Q62392, Q3TY48, Q3UG87	Gene names	Phlda1, Tdag51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Proline- and glutamine-rich protein) (PQR protein).

PRP2_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.006810 (rank : 95)
Query Neighborhood Hits	86	Target Neighborhood Hits	347	Shared Neighborhood Hits	3
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

BMP15_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.436454 (rank : 57)
Query Neighborhood Hits	86	Target Neighborhood Hits	64	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z0L4, Q3UT46	Gene names	Bmp15, Gdf9b
Domain Architecture
Description	Bone morphogenetic protein 15 precursor (BMP-15) (Growth/differentiation factor 9B) (GDF-9B).

GDF9_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.402683 (rank : 59)
Query Neighborhood Hits	86	Target Neighborhood Hits	68	Shared Neighborhood Hits	54
SwissProt Accessions	O60383	Gene names	GDF9
Domain Architecture
Description	Growth/differentiation factor 9 precursor (GDF-9).

GDF9_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.405092 (rank : 58)
Query Neighborhood Hits	86	Target Neighborhood Hits	63	Shared Neighborhood Hits	54
SwissProt Accessions	Q07105	Gene names	Gdf9, Gdf-9
Domain Architecture
Description	Growth/differentiation factor 9 precursor (GDF-9).

GDNF_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.051098 (rank : 73)
Query Neighborhood Hits	86	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P39905, Q96L44, Q9UD33, Q9UP97	Gene names	GDNF
Domain Architecture
Description	Glial cell line-derived neurotrophic factor precursor (Astrocyte- derived trophic factor 1) (ATF-1).

GDNF_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.052205 (rank : 72)
Query Neighborhood Hits	86	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P48540, O09058, P70446, P97919, P97920	Gene names	Gdnf
Domain Architecture
Description	Glial cell line-derived neurotrophic factor precursor.

INHA_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.347552 (rank : 61)
Query Neighborhood Hits	86	Target Neighborhood Hits	66	Shared Neighborhood Hits	55
SwissProt Accessions	P05111	Gene names	INHA
Domain Architecture
Description	Inhibin alpha chain precursor.

INHA_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.348044 (rank : 60)
Query Neighborhood Hits	86	Target Neighborhood Hits	66	Shared Neighborhood Hits	53
SwissProt Accessions	Q04997	Gene names	Inha
Domain Architecture
Description	Inhibin alpha chain precursor.

LEFTB_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.215716 (rank : 66)
Query Neighborhood Hits	86	Target Neighborhood Hits	58	Shared Neighborhood Hits	52
SwissProt Accessions	P57785	Gene names	Leftb, Lefty2
Domain Architecture	No domain graphic available
Description	Left-right determination factor B precursor (Lefty-2 protein).

PSPN_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.100332 (rank : 71)
Query Neighborhood Hits	86	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	O60542	Gene names	PSPN
Domain Architecture
Description	Persephin precursor (PSP).

TGFB4_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.237736 (rank : 64)
Query Neighborhood Hits	86	Target Neighborhood Hits	60	Shared Neighborhood Hits	54
SwissProt Accessions	O00292, O75611, Q8NBQ9	Gene names	EBAF, LEFTA, LEFTYA, TGFB4
Domain Architecture
Description	Transforming growth factor beta-4 precursor (TGF-beta-4) (Endometrial bleeding-associated factor) (Left-right determination factor A) (Lefty-A protein).

TGFB4_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.218083 (rank : 65)
Query Neighborhood Hits	86	Target Neighborhood Hits	59	Shared Neighborhood Hits	52
SwissProt Accessions	Q64280	Gene names	Ebaf, Lefty, Lefty1, Stra3, Tgfb4
Domain Architecture
Description	Transforming growth factor beta-4 precursor (TGF-beta-4) (Lefty protein) (Lefty-1 protein) (STRA3 protein).

Hits sorted by NC score

MIS_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	86	Target Neighborhood Hits	86	Shared Neighborhood Hits	86
SwissProt Accessions	P27106	Gene names	Amh
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

MIS_HUMAN
NC score	0.962713 (rank : 2)	θ value	4.53388e-177 (rank : 2)
Query Neighborhood Hits	86	Target Neighborhood Hits	87	Shared Neighborhood Hits	61
SwissProt Accessions	P03971, O75246	Gene names	AMH, MIF
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

GDF1_MOUSE
NC score	0.596224 (rank : 3)	θ value	1.06045e-08 (rank : 3)
Query Neighborhood Hits	86	Target Neighborhood Hits	71	Shared Neighborhood Hits	58
SwissProt Accessions	P20863	Gene names	Gdf1, Gdf-1
Domain Architecture
Description	Embryonic growth/differentiation factor 1 precursor (GDF-1).

GDF1_HUMAN
NC score	0.588581 (rank : 4)	θ value	1.80886e-08 (rank : 4)
Query Neighborhood Hits	86	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	P27539, O43344	Gene names	GDF1
Domain Architecture
Description	Embryonic growth/differentiation factor 1 precursor (GDF-1).

GDF11_MOUSE
NC score	0.557531 (rank : 5)	θ value	1.43324e-05 (rank : 7)
Query Neighborhood Hits	86	Target Neighborhood Hits	73	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z1W4, Q9QX55, Q9R221	Gene names	Gdf11, Bmp11
Domain Architecture
Description	Growth/differentiation factor 11 precursor (GDF-11) (Bone morphogenetic protein 11).

GDF11_HUMAN
NC score	0.557302 (rank : 6)	θ value	1.43324e-05 (rank : 6)
Query Neighborhood Hits	86	Target Neighborhood Hits	73	Shared Neighborhood Hits	58
SwissProt Accessions	O95390, Q9UID1, Q9UID2	Gene names	GDF11, BMP11
Domain Architecture
Description	Growth/differentiation factor 11 precursor (GDF-11) (Bone morphogenetic protein 11).

INHBC_MOUSE
NC score	0.554260 (rank : 7)	θ value	8.40245e-06 (rank : 5)
Query Neighborhood Hits	86	Target Neighborhood Hits	65	Shared Neighborhood Hits	57
SwissProt Accessions	P55104, Q61452	Gene names	Inhbc
Domain Architecture
Description	Inhibin beta C chain precursor (Activin beta-C chain).

GDF8_MOUSE
NC score	0.551530 (rank : 8)	θ value	7.1131e-05 (rank : 14)
Query Neighborhood Hits	86	Target Neighborhood Hits	71	Shared Neighborhood Hits	58
SwissProt Accessions	O08689	Gene names	Gdf8, Mstn
Domain Architecture
Description	Growth/differentiation factor 8 precursor (GDF-8) (Myostatin).

GDF8_HUMAN
NC score	0.551508 (rank : 9)	θ value	7.1131e-05 (rank : 13)
Query Neighborhood Hits	86	Target Neighborhood Hits	71	Shared Neighborhood Hits	58
SwissProt Accessions	O14793, Q6B0H2	Gene names	GDF8, MSTN
Domain Architecture
Description	Growth/differentiation factor 8 precursor (GDF-8) (Myostatin).

INHBE_MOUSE
NC score	0.548298 (rank : 10)	θ value	0.00102713 (rank : 26)
Query Neighborhood Hits	86	Target Neighborhood Hits	69	Shared Neighborhood Hits	57
SwissProt Accessions	O08717	Gene names	Inhbe
Domain Architecture
Description	Inhibin beta E chain precursor (Activin beta-E chain).

GDF7_MOUSE
NC score	0.547927 (rank : 11)	θ value	0.000158464 (rank : 20)
Query Neighborhood Hits	86	Target Neighborhood Hits	70	Shared Neighborhood Hits	57
SwissProt Accessions	P43029, Q7TNX4, Q99MY1	Gene names	Gdf7, Gdf-7
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 7 precursor (GDF-7).

INHBE_HUMAN
NC score	0.546497 (rank : 12)	θ value	0.00175202 (rank : 28)
Query Neighborhood Hits	86	Target Neighborhood Hits	69	Shared Neighborhood Hits	57
SwissProt Accessions	P58166	Gene names	INHBE
Domain Architecture
Description	Inhibin beta E chain precursor (Activin beta-E chain).

GDF7_HUMAN
NC score	0.546285 (rank : 13)	θ value	0.000270298 (rank : 24)
Query Neighborhood Hits	86	Target Neighborhood Hits	66	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z4P5	Gene names	GDF7
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 7 precursor (GDF-7).

INHBB_HUMAN
NC score	0.542157 (rank : 14)	θ value	0.00035302 (rank : 25)
Query Neighborhood Hits	86	Target Neighborhood Hits	70	Shared Neighborhood Hits	58
SwissProt Accessions	P09529, Q8N1D3	Gene names	INHBB
Domain Architecture
Description	Inhibin beta B chain precursor (Activin beta-B chain).

GDF5_HUMAN
NC score	0.536088 (rank : 15)	θ value	0.000270298 (rank : 22)
Query Neighborhood Hits	86	Target Neighborhood Hits	103	Shared Neighborhood Hits	57
SwissProt Accessions	P43026, Q96SB1	Gene names	GDF5, CDMP1
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Radotermin).

GDF5_MOUSE
NC score	0.535848 (rank : 16)	θ value	0.000270298 (rank : 23)
Query Neighborhood Hits	86	Target Neighborhood Hits	99	Shared Neighborhood Hits	57
SwissProt Accessions	P43027	Gene names	Gdf5, Bp, Gdf-5
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5).

BMP2_MOUSE
NC score	0.535078 (rank : 17)	θ value	7.1131e-05 (rank : 11)
Query Neighborhood Hits	86	Target Neighborhood Hits	76	Shared Neighborhood Hits	57
SwissProt Accessions	P21274	Gene names	Bmp2, Bmp-2
Domain Architecture
Description	Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A).

BMP2_HUMAN
NC score	0.535058 (rank : 18)	θ value	7.1131e-05 (rank : 10)
Query Neighborhood Hits	86	Target Neighborhood Hits	74	Shared Neighborhood Hits	57
SwissProt Accessions	P12643	Gene names	BMP2, BMP2A
Domain Architecture
Description	Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A).

GDF6_MOUSE
NC score	0.533561 (rank : 19)	θ value	0.00390308 (rank : 36)
Query Neighborhood Hits	86	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	P43028, Q70UT4	Gene names	Gdf6, Gdf-6, Gdf16
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 6 precursor (GDF-6) (Growth/differentiation factor 16).

GDF6_HUMAN
NC score	0.533456 (rank : 20)	θ value	0.00390308 (rank : 35)
Query Neighborhood Hits	86	Target Neighborhood Hits	76	Shared Neighborhood Hits	57
SwissProt Accessions	Q6KF10, Q6PI58	Gene names	GDF6, GDF16
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 6 precursor (GDF-6) (Growth/differentiation factor 16).

NODAL_HUMAN
NC score	0.531856 (rank : 21)	θ value	0.000121331 (rank : 16)
Query Neighborhood Hits	86	Target Neighborhood Hits	66	Shared Neighborhood Hits	57
SwissProt Accessions	Q96S42, Q2M3A5, Q8N4V3	Gene names	NODAL
Domain Architecture
Description	Nodal homolog precursor.

INHBC_HUMAN
NC score	0.531673 (rank : 22)	θ value	0.00509761 (rank : 38)
Query Neighborhood Hits	86	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	P55103	Gene names	INHBC
Domain Architecture
Description	Inhibin beta C chain precursor (Activin beta-C chain).

BMP4_MOUSE
NC score	0.531610 (rank : 23)	θ value	9.29e-05 (rank : 15)
Query Neighborhood Hits	86	Target Neighborhood Hits	71	Shared Neighborhood Hits	58
SwissProt Accessions	P21275	Gene names	Bmp4, Bmp-4, Dvr-4
Domain Architecture
Description	Bone morphogenetic protein 4 precursor (BMP-4) (BMP-2B).

BMP4_HUMAN
NC score	0.531538 (rank : 24)	θ value	0.000158464 (rank : 19)
Query Neighborhood Hits	86	Target Neighborhood Hits	72	Shared Neighborhood Hits	59
SwissProt Accessions	P12644, Q9UM80	Gene names	BMP4, BMP2B, DVR4
Domain Architecture
Description	Bone morphogenetic protein 4 precursor (BMP-4) (BMP-2B).

GDF15_HUMAN
NC score	0.525764 (rank : 25)	θ value	0.00020696 (rank : 21)
Query Neighborhood Hits	86	Target Neighborhood Hits	68	Shared Neighborhood Hits	59
SwissProt Accessions	Q99988, O14629, P78360, Q9NRT0	Gene names	GDF15, MIC1, PDF, PLAB, PTGFB
Domain Architecture
Description	Growth/differentiation factor 15 precursor (GDF-15) (Placental bone morphogenetic protein) (Placental TGF-beta) (Macrophage inhibitory cytokine 1) (MIC-1) (Prostate differentiation factor) (NSAID-regulated protein 1) (NRG-1).

BMP3_MOUSE
NC score	0.524146 (rank : 26)	θ value	2.44474e-05 (rank : 8)
Query Neighborhood Hits	86	Target Neighborhood Hits	82	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BHE5	Gene names	Bmp3
Domain Architecture	No domain graphic available
Description	Bone morphogenetic protein 3 precursor (BMP-3).

NODAL_MOUSE
NC score	0.523561 (rank : 27)	θ value	0.00869519 (rank : 40)
Query Neighborhood Hits	86	Target Neighborhood Hits	66	Shared Neighborhood Hits	57
SwissProt Accessions	P43021	Gene names	Nodal
Domain Architecture
Description	Nodal precursor.

BMP3_HUMAN
NC score	0.521340 (rank : 28)	θ value	3.19293e-05 (rank : 9)
Query Neighborhood Hits	86	Target Neighborhood Hits	85	Shared Neighborhood Hits	56
SwissProt Accessions	P12645	Gene names	BMP3
Domain Architecture
Description	Bone morphogenetic protein 3 precursor (BMP-3) (Osteogenin) (BMP-3A).

BMP10_MOUSE
NC score	0.520791 (rank : 29)	θ value	0.00134147 (rank : 27)
Query Neighborhood Hits	86	Target Neighborhood Hits	75	Shared Neighborhood Hits	57
SwissProt Accessions	Q9R229, Q9Z1V8	Gene names	Bmp10
Domain Architecture
Description	Bone morphogenetic protein 10 precursor (BMP-10).

INHBA_HUMAN
NC score	0.520710 (rank : 30)	θ value	0.0148317 (rank : 42)
Query Neighborhood Hits	86	Target Neighborhood Hits	75	Shared Neighborhood Hits	57
SwissProt Accessions	P08476, Q14599	Gene names	INHBA
Domain Architecture
Description	Inhibin beta A chain precursor (Activin beta-A chain) (Erythroid differentiation protein) (EDF).

INHBA_MOUSE
NC score	0.520466 (rank : 31)	θ value	0.0148317 (rank : 43)
Query Neighborhood Hits	86	Target Neighborhood Hits	75	Shared Neighborhood Hits	57
SwissProt Accessions	Q04998	Gene names	Inhba
Domain Architecture
Description	Inhibin beta A chain precursor (Activin beta-A chain).

BMP10_HUMAN
NC score	0.520251 (rank : 32)	θ value	0.00390308 (rank : 33)
Query Neighborhood Hits	86	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	O95393	Gene names	BMP10
Domain Architecture
Description	Bone morphogenetic protein 10 precursor (BMP-10).

GDF2_HUMAN
NC score	0.517347 (rank : 33)	θ value	0.00390308 (rank : 34)
Query Neighborhood Hits	86	Target Neighborhood Hits	77	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UK05, Q9Y571	Gene names	GDF2, BMP9
Domain Architecture
Description	Growth/differentiation factor 2 precursor (GDF-2) (Bone morphogenetic protein 9) (BMP-9).

GDF15_MOUSE
NC score	0.516973 (rank : 34)	θ value	0.0563607 (rank : 53)
Query Neighborhood Hits	86	Target Neighborhood Hits	71	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z0J7	Gene names	Gdf15, Sbf
Domain Architecture
Description	Growth/differentiation factor 15 precursor (GDF-15).

BMP3B_MOUSE
NC score	0.516688 (rank : 35)	θ value	7.1131e-05 (rank : 12)
Query Neighborhood Hits	86	Target Neighborhood Hits	80	Shared Neighborhood Hits	56
SwissProt Accessions	P97737	Gene names	Gdf10, Bmp3b
Domain Architecture
Description	Bone morphogenetic protein 3b precursor (BMP-3b) (Growth/differentiation factor 10) (GDF-10).

BMP3B_HUMAN
NC score	0.515574 (rank : 36)	θ value	0.000158464 (rank : 18)
Query Neighborhood Hits	86	Target Neighborhood Hits	90	Shared Neighborhood Hits	57
SwissProt Accessions	P55107, Q9UCX6	Gene names	GDF10, BMP3B
Domain Architecture
Description	Bone morphogenetic protein 3b precursor (BMP-3b) (Growth/differentiation factor 10) (GDF-10) (Bone-inducing protein) (BIP).

GDF2_MOUSE
NC score	0.515171 (rank : 37)	θ value	0.0148317 (rank : 41)
Query Neighborhood Hits	86	Target Neighborhood Hits	70	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WV56, Q9QZE0	Gene names	Gdf2, Bmp9
Domain Architecture
Description	Growth/differentiation factor 2 precursor (GDF-2) (Bone morphogenetic protein 9) (BMP-9).

GDF3_MOUSE
NC score	0.513323 (rank : 38)	θ value	0.163984 (rank : 55)
Query Neighborhood Hits	86	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	Q07104	Gene names	Gdf3, Gdf-3, Vgr-2
Domain Architecture
Description	Growth/differentiation factor 3 precursor (GDF-3) (VG-1-related protein 2).

BMP6_HUMAN
NC score	0.508724 (rank : 39)	θ value	0.00298849 (rank : 31)
Query Neighborhood Hits	86	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	P22004	Gene names	BMP6, VGR
Domain Architecture
Description	Bone morphogenetic protein 6 precursor (BMP-6).

GDF3_HUMAN
NC score	0.507915 (rank : 40)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	86	Target Neighborhood Hits	65	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NR23, Q8NEJ4	Gene names	GDF3
Domain Architecture
Description	Growth/differentiation factor 3 precursor (GDF-3).

BMP6_MOUSE
NC score	0.507484 (rank : 41)	θ value	0.00298849 (rank : 32)
Query Neighborhood Hits	86	Target Neighborhood Hits	84	Shared Neighborhood Hits	59
SwissProt Accessions	P20722	Gene names	Bmp6, Bmp-6, Vgr1
Domain Architecture
Description	Bone morphogenetic protein 6 precursor (BMP-6) (VG-1-related protein) (VGR-1).

BMP7_HUMAN
NC score	0.499592 (rank : 42)	θ value	0.00509761 (rank : 37)
Query Neighborhood Hits	86	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	P18075, Q9H512, Q9NTQ7	Gene names	BMP7, OP1
Domain Architecture
Description	Bone morphogenetic protein 7 precursor (BMP-7) (Osteogenic protein 1) (OP-1) (Eptotermin alfa).

BMP7_MOUSE
NC score	0.498700 (rank : 43)	θ value	0.00665767 (rank : 39)
Query Neighborhood Hits	86	Target Neighborhood Hits	65	Shared Neighborhood Hits	57
SwissProt Accessions	P23359, Q91XF7	Gene names	Bmp7, Bmp-7, Op1
Domain Architecture
Description	Bone morphogenetic protein 7 precursor (BMP-7) (Osteogenic protein 1) (OP-1).

BMP8A_MOUSE
NC score	0.496657 (rank : 44)	θ value	0.0252991 (rank : 46)
Query Neighborhood Hits	86	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	P34821	Gene names	Bmp8a, Bmp-8, Bmp8
Domain Architecture
Description	Bone morphogenetic protein 8A precursor (BMP-8A) (Osteogenic protein 2) (OP-2).

TGFB1_HUMAN
NC score	0.495653 (rank : 45)	θ value	0.00228821 (rank : 30)
Query Neighborhood Hits	86	Target Neighborhood Hits	64	Shared Neighborhood Hits	57
SwissProt Accessions	P01137, Q9UCG4	Gene names	TGFB1, TGFB
Domain Architecture
Description	Transforming growth factor beta-1 precursor (TGF-beta-1) [Contains: Latency-associated peptide (LAP)].

BMP5_HUMAN
NC score	0.495204 (rank : 46)	θ value	0.0330416 (rank : 47)
Query Neighborhood Hits	86	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	P22003, Q9H547, Q9NTM5	Gene names	BMP5
Domain Architecture
Description	Bone morphogenetic protein 5 precursor (BMP-5).

BMP5_MOUSE
NC score	0.494616 (rank : 47)	θ value	0.0330416 (rank : 48)
Query Neighborhood Hits	86	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	P49003	Gene names	Bmp5, Bmp-5
Domain Architecture
Description	Bone morphogenetic protein 5 precursor (BMP-5).

TGFB1_MOUSE
NC score	0.494466 (rank : 48)	θ value	0.00175202 (rank : 29)
Query Neighborhood Hits	86	Target Neighborhood Hits	64	Shared Neighborhood Hits	57
SwissProt Accessions	P04202	Gene names	Tgfb1
Domain Architecture
Description	Transforming growth factor beta-1 precursor (TGF-beta-1) [Contains: Latency-associated peptide (LAP)].

BMP8A_HUMAN
NC score	0.494347 (rank : 49)	θ value	0.0431538 (rank : 50)
Query Neighborhood Hits	86	Target Neighborhood Hits	66	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z5Y6, Q5T3A5	Gene names	BMP8A
Domain Architecture	No domain graphic available
Description	Bone morphogenetic protein 8A precursor (BMP-8A).

BMP8B_HUMAN
NC score	0.492037 (rank : 50)	θ value	0.0961366 (rank : 54)
Query Neighborhood Hits	86	Target Neighborhood Hits	65	Shared Neighborhood Hits	57
SwissProt Accessions	P34820, Q53ZM7, Q9NUF0	Gene names	BMP8B, BMP8
Domain Architecture
Description	Bone morphogenetic protein 8B precursor (BMP-8B) (BMP-8) (Osteogenic protein 2) (OP-2).

BMP8B_MOUSE
NC score	0.489529 (rank : 51)	θ value	0.0431538 (rank : 51)
Query Neighborhood Hits	86	Target Neighborhood Hits	70	Shared Neighborhood Hits	57
SwissProt Accessions	P55105	Gene names	Bmp8b
Domain Architecture
Description	Bone morphogenetic protein 8B precursor (BMP-8B).

TGFB3_HUMAN
NC score	0.485024 (rank : 52)	θ value	0.0148317 (rank : 44)
Query Neighborhood Hits	86	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	P10600	Gene names	TGFB3
Domain Architecture
Description	Transforming growth factor beta-3 precursor (TGF-beta-3).

TGFB3_MOUSE
NC score	0.483019 (rank : 53)	θ value	0.0330416 (rank : 49)
Query Neighborhood Hits	86	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	P17125	Gene names	Tgfb3
Domain Architecture
Description	Transforming growth factor beta-3 precursor (TGF-beta-3).

TGFB2_MOUSE
NC score	0.477832 (rank : 54)	θ value	0.0193708 (rank : 45)
Query Neighborhood Hits	86	Target Neighborhood Hits	70	Shared Neighborhood Hits	57
SwissProt Accessions	P27090	Gene names	Tgfb2
Domain Architecture
Description	Transforming growth factor beta-2 precursor (TGF-beta-2).

TGFB2_HUMAN
NC score	0.474729 (rank : 55)	θ value	0.0431538 (rank : 52)
Query Neighborhood Hits	86	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	P61812, P08112, Q15579, Q15581, Q4VAV9	Gene names	TGFB2
Domain Architecture
Description	Transforming growth factor beta-2 precursor (TGF-beta-2) (Glioblastoma-derived T-cell suppressor factor) (G-TSF) (BSC-1 cell growth inhibitor) (Polyergin) (Cetermin).

BMP15_HUMAN
NC score	0.454567 (rank : 56)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	86	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	O95972, Q5JST1, Q9UMS1	Gene names	BMP15, GDF9B
Domain Architecture
Description	Bone morphogenetic protein 15 precursor (BMP-15) (Growth/differentiation factor 9B) (GDF-9B).

BMP15_MOUSE
NC score	0.436454 (rank : 57)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	86	Target Neighborhood Hits	64	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z0L4, Q3UT46	Gene names	Bmp15, Gdf9b
Domain Architecture
Description	Bone morphogenetic protein 15 precursor (BMP-15) (Growth/differentiation factor 9B) (GDF-9B).

GDF9_MOUSE
NC score	0.405092 (rank : 58)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	86	Target Neighborhood Hits	63	Shared Neighborhood Hits	54
SwissProt Accessions	Q07105	Gene names	Gdf9, Gdf-9
Domain Architecture
Description	Growth/differentiation factor 9 precursor (GDF-9).

GDF9_HUMAN
NC score	0.402683 (rank : 59)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	86	Target Neighborhood Hits	68	Shared Neighborhood Hits	54
SwissProt Accessions	O60383	Gene names	GDF9
Domain Architecture
Description	Growth/differentiation factor 9 precursor (GDF-9).

INHA_MOUSE
NC score	0.348044 (rank : 60)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	86	Target Neighborhood Hits	66	Shared Neighborhood Hits	53
SwissProt Accessions	Q04997	Gene names	Inha
Domain Architecture
Description	Inhibin alpha chain precursor.

INHA_HUMAN
NC score	0.347552 (rank : 61)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	86	Target Neighborhood Hits	66	Shared Neighborhood Hits	55
SwissProt Accessions	P05111	Gene names	INHA
Domain Architecture
Description	Inhibin alpha chain precursor.

PSPN_MOUSE
NC score	0.245208 (rank : 62)	θ value	0.000121331 (rank : 17)
Query Neighborhood Hits	86	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	O70300	Gene names	Pspn
Domain Architecture
Description	Persephin precursor (PSP).

LEFTB_HUMAN
NC score	0.240771 (rank : 63)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	86	Target Neighborhood Hits	63	Shared Neighborhood Hits	55
SwissProt Accessions	O75610	Gene names	LEFTB, LEFTYB
Domain Architecture
Description	Left-right determination factor B precursor (Lefty-B protein).

TGFB4_HUMAN
NC score	0.237736 (rank : 64)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	86	Target Neighborhood Hits	60	Shared Neighborhood Hits	54
SwissProt Accessions	O00292, O75611, Q8NBQ9	Gene names	EBAF, LEFTA, LEFTYA, TGFB4
Domain Architecture
Description	Transforming growth factor beta-4 precursor (TGF-beta-4) (Endometrial bleeding-associated factor) (Left-right determination factor A) (Lefty-A protein).

TGFB4_MOUSE
NC score	0.218083 (rank : 65)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	86	Target Neighborhood Hits	59	Shared Neighborhood Hits	52
SwissProt Accessions	Q64280	Gene names	Ebaf, Lefty, Lefty1, Stra3, Tgfb4
Domain Architecture
Description	Transforming growth factor beta-4 precursor (TGF-beta-4) (Lefty protein) (Lefty-1 protein) (STRA3 protein).

LEFTB_MOUSE
NC score	0.215716 (rank : 66)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	86	Target Neighborhood Hits	58	Shared Neighborhood Hits	52
SwissProt Accessions	P57785	Gene names	Leftb, Lefty2
Domain Architecture	No domain graphic available
Description	Left-right determination factor B precursor (Lefty-2 protein).

NRTN_HUMAN
NC score	0.163325 (rank : 67)	θ value	0.279714 (rank : 57)
Query Neighborhood Hits	86	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q99748	Gene names	NRTN
Domain Architecture
Description	Neurturin precursor.

NRTN_MOUSE
NC score	0.126758 (rank : 68)	θ value	1.06291 (rank : 62)
Query Neighborhood Hits	86	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	P97463	Gene names	Nrtn
Domain Architecture
Description	Neurturin precursor.

ARTN_HUMAN
NC score	0.126086 (rank : 69)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	86	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T4W7, O95441, O96030, Q6P6A3	Gene names	ARTN, EVN
Domain Architecture	No domain graphic available
Description	Artemin precursor (Enovin) (Neublastin).

ARTN_MOUSE
NC score	0.104758 (rank : 70)	θ value	0.279714 (rank : 56)
Query Neighborhood Hits	86	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z0L2, Q3SXF4, Q3SXF5	Gene names	Artn
Domain Architecture	No domain graphic available
Description	Artemin precursor.

PSPN_HUMAN
NC score	0.100332 (rank : 71)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	86	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	O60542	Gene names	PSPN
Domain Architecture
Description	Persephin precursor (PSP).

GDNF_MOUSE
NC score	0.052205 (rank : 72)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	86	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P48540, O09058, P70446, P97919, P97920	Gene names	Gdnf
Domain Architecture
Description	Glial cell line-derived neurotrophic factor precursor.

GDNF_HUMAN
NC score	0.051098 (rank : 73)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	86	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P39905, Q96L44, Q9UD33, Q9UP97	Gene names	GDNF
Domain Architecture
Description	Glial cell line-derived neurotrophic factor precursor (Astrocyte- derived trophic factor 1) (ATF-1).

GSCR1_HUMAN
NC score	0.039607 (rank : 74)	θ value	0.365318 (rank : 58)
Query Neighborhood Hits	86	Target Neighborhood Hits	674	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

DGKK_HUMAN
NC score	0.038596 (rank : 75)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	86	Target Neighborhood Hits	378	Shared Neighborhood Hits	5
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

PHLA1_HUMAN
NC score	0.034725 (rank : 76)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	86	Target Neighborhood Hits	121	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

WASF1_HUMAN
NC score	0.034425 (rank : 77)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	86	Target Neighborhood Hits	260	Shared Neighborhood Hits	7
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WASF1_MOUSE
NC score	0.030248 (rank : 78)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	86	Target Neighborhood Hits	261	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

EPM2A_MOUSE
NC score	0.029607 (rank : 79)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	86	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WUA5, Q8BY80	Gene names	Epm2a
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

SETD2_HUMAN
NC score	0.029018 (rank : 80)	θ value	1.06291 (rank : 64)
Query Neighborhood Hits	86	Target Neighborhood Hits	412	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

HCFC1_HUMAN
NC score	0.028706 (rank : 81)	θ value	1.38821 (rank : 65)
Query Neighborhood Hits	86	Target Neighborhood Hits	331	Shared Neighborhood Hits	5
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

TPSN_MOUSE
NC score	0.027091 (rank : 82)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	86	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R233, O70317, Q91YE0, Q91YE1, Q9QWT7, Q9Z1W3	Gene names	Tapbp, Tapa
Domain Architecture
Description	Tapasin precursor (TPSN) (TPN) (TAP-binding protein) (TAP-associated protein).

GGN_HUMAN
NC score	0.025188 (rank : 83)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	86	Target Neighborhood Hits	269	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

PHLA1_MOUSE
NC score	0.024583 (rank : 84)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	86	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	Q62392, Q3TY48, Q3UG87	Gene names	Phlda1, Tdag51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Proline- and glutamine-rich protein) (PQR protein).

EPM2A_HUMAN
NC score	0.024583 (rank : 85)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	86	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	O95278, O95483, Q8IU96, Q8IX24, Q8IX25, Q9BS66, Q9UEN2	Gene names	EPM2A
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

HCFC1_MOUSE
NC score	0.024447 (rank : 86)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	86	Target Neighborhood Hits	348	Shared Neighborhood Hits	6
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

MLL3_MOUSE
NC score	0.024322 (rank : 87)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	86	Target Neighborhood Hits	1399	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MOT8_MOUSE
NC score	0.021240 (rank : 88)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	86	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	O70324, Q8K3S9	Gene names	Slc16a2, Mct8, Xpct
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

ALEX_HUMAN
NC score	0.019400 (rank : 89)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	86	Target Neighborhood Hits	361	Shared Neighborhood Hits	7
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

BAZ2A_HUMAN
NC score	0.017700 (rank : 90)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	86	Target Neighborhood Hits	780	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

ASPC1_MOUSE
NC score	0.016762 (rank : 91)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	86	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VBT9, Q3UKD1, Q6V7K5, Q9CT64	Gene names	Aspscr1, Tug
Domain Architecture	No domain graphic available
Description	Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosome region candidate 1 homolog).

GNDS_HUMAN
NC score	0.013628 (rank : 92)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	86	Target Neighborhood Hits	201	Shared Neighborhood Hits	6
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

BRD4_HUMAN
NC score	0.011644 (rank : 93)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	86	Target Neighborhood Hits	851	Shared Neighborhood Hits	9
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

PTN18_MOUSE
NC score	0.011543 (rank : 94)	θ value	1.06291 (rank : 63)
Query Neighborhood Hits	86	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PRP2_MOUSE
NC score	0.006810 (rank : 95)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	86	Target Neighborhood Hits	347	Shared Neighborhood Hits	3
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRDM2_HUMAN
NC score	0.002102 (rank : 96)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	86	Target Neighborhood Hits	1135	Shared Neighborhood Hits	5
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

TITIN_HUMAN
NC score	-0.002214 (rank : 97)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	86	Target Neighborhood Hits	2923	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).