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Network neighborhood for query Sequence : GDF15_HUMAN

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GDF15_HUMAN
SwissProt Accessions	Q99988, O14629, P78360, Q9NRT0	Gene names	GDF15, MIC1, PDF, PLAB, PTGFB
Domain Architecture
Description	Growth/differentiation factor 15 precursor (GDF-15) (Placental bone morphogenetic protein) (Placental TGF-beta) (Macrophage inhibitory cytokine 1) (MIC-1) (Prostate differentiation factor) (NSAID-regulated protein 1) (NRG-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GDF15_HUMAN
θ value	2.25536e-168 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	68
SwissProt Accessions	Q99988, O14629, P78360, Q9NRT0	Gene names	GDF15, MIC1, PDF, PLAB, PTGFB
Domain Architecture
Description	Growth/differentiation factor 15 precursor (GDF-15) (Placental bone morphogenetic protein) (Placental TGF-beta) (Macrophage inhibitory cytokine 1) (MIC-1) (Prostate differentiation factor) (NSAID-regulated protein 1) (NRG-1).

GDF15_MOUSE
θ value	1.03614e-88 (rank : 2)	NC score	0.985663 (rank : 2)
Query Neighborhood Hits	68	Target Neighborhood Hits	71	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0J7	Gene names	Gdf15, Sbf
Domain Architecture
Description	Growth/differentiation factor 15 precursor (GDF-15).

BMP7_MOUSE
θ value	4.91457e-14 (rank : 3)	NC score	0.850094 (rank : 12)
Query Neighborhood Hits	68	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	P23359, Q91XF7	Gene names	Bmp7, Bmp-7, Op1
Domain Architecture
Description	Bone morphogenetic protein 7 precursor (BMP-7) (Osteogenic protein 1) (OP-1).

BMP6_HUMAN
θ value	6.41864e-14 (rank : 4)	NC score	0.854661 (rank : 8)
Query Neighborhood Hits	68	Target Neighborhood Hits	82	Shared Neighborhood Hits	65
SwissProt Accessions	P22004	Gene names	BMP6, VGR
Domain Architecture
Description	Bone morphogenetic protein 6 precursor (BMP-6).

BMP5_HUMAN
θ value	1.42992e-13 (rank : 5)	NC score	0.845754 (rank : 18)
Query Neighborhood Hits	68	Target Neighborhood Hits	72	Shared Neighborhood Hits	65
SwissProt Accessions	P22003, Q9H547, Q9NTM5	Gene names	BMP5
Domain Architecture
Description	Bone morphogenetic protein 5 precursor (BMP-5).

BMP5_MOUSE
θ value	1.42992e-13 (rank : 6)	NC score	0.845789 (rank : 17)
Query Neighborhood Hits	68	Target Neighborhood Hits	72	Shared Neighborhood Hits	65
SwissProt Accessions	P49003	Gene names	Bmp5, Bmp-5
Domain Architecture
Description	Bone morphogenetic protein 5 precursor (BMP-5).

BMP6_MOUSE
θ value	1.42992e-13 (rank : 7)	NC score	0.853364 (rank : 9)
Query Neighborhood Hits	68	Target Neighborhood Hits	84	Shared Neighborhood Hits	65
SwissProt Accessions	P20722	Gene names	Bmp6, Bmp-6, Vgr1
Domain Architecture
Description	Bone morphogenetic protein 6 precursor (BMP-6) (VG-1-related protein) (VGR-1).

BMP7_HUMAN
θ value	1.42992e-13 (rank : 8)	NC score	0.848879 (rank : 14)
Query Neighborhood Hits	68	Target Neighborhood Hits	67	Shared Neighborhood Hits	65
SwissProt Accessions	P18075, Q9H512, Q9NTQ7	Gene names	BMP7, OP1
Domain Architecture
Description	Bone morphogenetic protein 7 precursor (BMP-7) (Osteogenic protein 1) (OP-1) (Eptotermin alfa).

BMP8A_HUMAN
θ value	2.0648e-12 (rank : 9)	NC score	0.843863 (rank : 21)
Query Neighborhood Hits	68	Target Neighborhood Hits	66	Shared Neighborhood Hits	65
SwissProt Accessions	Q7Z5Y6, Q5T3A5	Gene names	BMP8A
Domain Architecture	No domain graphic available
Description	Bone morphogenetic protein 8A precursor (BMP-8A).

BMP8B_HUMAN
θ value	2.0648e-12 (rank : 10)	NC score	0.844379 (rank : 19)
Query Neighborhood Hits	68	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	P34820, Q53ZM7, Q9NUF0	Gene names	BMP8B, BMP8
Domain Architecture
Description	Bone morphogenetic protein 8B precursor (BMP-8B) (BMP-8) (Osteogenic protein 2) (OP-2).

GDF7_MOUSE
θ value	2.0648e-12 (rank : 11)	NC score	0.864948 (rank : 4)
Query Neighborhood Hits	68	Target Neighborhood Hits	70	Shared Neighborhood Hits	65
SwissProt Accessions	P43029, Q7TNX4, Q99MY1	Gene names	Gdf7, Gdf-7
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 7 precursor (GDF-7).

GDF1_HUMAN
θ value	2.69671e-12 (rank : 12)	NC score	0.868418 (rank : 3)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	65
SwissProt Accessions	P27539, O43344	Gene names	GDF1
Domain Architecture
Description	Embryonic growth/differentiation factor 1 precursor (GDF-1).

GDF7_HUMAN
θ value	4.59992e-12 (rank : 13)	NC score	0.863777 (rank : 5)
Query Neighborhood Hits	68	Target Neighborhood Hits	66	Shared Neighborhood Hits	65
SwissProt Accessions	Q7Z4P5	Gene names	GDF7
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 7 precursor (GDF-7).

INHBE_HUMAN
θ value	4.59992e-12 (rank : 14)	NC score	0.841343 (rank : 23)
Query Neighborhood Hits	68	Target Neighborhood Hits	69	Shared Neighborhood Hits	65
SwissProt Accessions	P58166	Gene names	INHBE
Domain Architecture
Description	Inhibin beta E chain precursor (Activin beta-E chain).

INHBE_MOUSE
θ value	4.59992e-12 (rank : 15)	NC score	0.840849 (rank : 25)
Query Neighborhood Hits	68	Target Neighborhood Hits	69	Shared Neighborhood Hits	65
SwissProt Accessions	O08717	Gene names	Inhbe
Domain Architecture
Description	Inhibin beta E chain precursor (Activin beta-E chain).

BMP8A_MOUSE
θ value	6.00763e-12 (rank : 16)	NC score	0.840938 (rank : 24)
Query Neighborhood Hits	68	Target Neighborhood Hits	67	Shared Neighborhood Hits	65
SwissProt Accessions	P34821	Gene names	Bmp8a, Bmp-8, Bmp8
Domain Architecture
Description	Bone morphogenetic protein 8A precursor (BMP-8A) (Osteogenic protein 2) (OP-2).

GDF9_MOUSE
θ value	6.00763e-12 (rank : 17)	NC score	0.813915 (rank : 37)
Query Neighborhood Hits	68	Target Neighborhood Hits	63	Shared Neighborhood Hits	59
SwissProt Accessions	Q07105	Gene names	Gdf9, Gdf-9
Domain Architecture
Description	Growth/differentiation factor 9 precursor (GDF-9).

GDF9_HUMAN
θ value	1.02475e-11 (rank : 18)	NC score	0.810097 (rank : 39)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	59
SwissProt Accessions	O60383	Gene names	GDF9
Domain Architecture
Description	Growth/differentiation factor 9 precursor (GDF-9).

GDF2_HUMAN
θ value	1.74796e-11 (rank : 19)	NC score	0.827809 (rank : 32)
Query Neighborhood Hits	68	Target Neighborhood Hits	77	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UK05, Q9Y571	Gene names	GDF2, BMP9
Domain Architecture
Description	Growth/differentiation factor 2 precursor (GDF-2) (Bone morphogenetic protein 9) (BMP-9).

NODAL_HUMAN
θ value	1.74796e-11 (rank : 20)	NC score	0.851774 (rank : 11)
Query Neighborhood Hits	68	Target Neighborhood Hits	66	Shared Neighborhood Hits	63
SwissProt Accessions	Q96S42, Q2M3A5, Q8N4V3	Gene names	NODAL
Domain Architecture
Description	Nodal homolog precursor.

GDF5_HUMAN
θ value	2.28291e-11 (rank : 21)	NC score	0.843915 (rank : 20)
Query Neighborhood Hits	68	Target Neighborhood Hits	103	Shared Neighborhood Hits	65
SwissProt Accessions	P43026, Q96SB1	Gene names	GDF5, CDMP1
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Radotermin).

GDF5_MOUSE
θ value	2.98157e-11 (rank : 22)	NC score	0.843320 (rank : 22)
Query Neighborhood Hits	68	Target Neighborhood Hits	99	Shared Neighborhood Hits	65
SwissProt Accessions	P43027	Gene names	Gdf5, Bp, Gdf-5
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5).

NODAL_MOUSE
θ value	5.08577e-11 (rank : 23)	NC score	0.849961 (rank : 13)
Query Neighborhood Hits	68	Target Neighborhood Hits	66	Shared Neighborhood Hits	63
SwissProt Accessions	P43021	Gene names	Nodal
Domain Architecture
Description	Nodal precursor.

BMP15_MOUSE
θ value	1.133e-10 (rank : 24)	NC score	0.833008 (rank : 31)
Query Neighborhood Hits	68	Target Neighborhood Hits	64	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z0L4, Q3UT46	Gene names	Bmp15, Gdf9b
Domain Architecture
Description	Bone morphogenetic protein 15 precursor (BMP-15) (Growth/differentiation factor 9B) (GDF-9B).

GDF6_HUMAN
θ value	1.9326e-10 (rank : 25)	NC score	0.848206 (rank : 15)
Query Neighborhood Hits	68	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	Q6KF10, Q6PI58	Gene names	GDF6, GDF16
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 6 precursor (GDF-6) (Growth/differentiation factor 16).

GDF6_MOUSE
θ value	1.9326e-10 (rank : 26)	NC score	0.847114 (rank : 16)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	65
SwissProt Accessions	P43028, Q70UT4	Gene names	Gdf6, Gdf-6, Gdf16
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 6 precursor (GDF-6) (Growth/differentiation factor 16).

GDF3_MOUSE
θ value	3.29651e-10 (rank : 27)	NC score	0.855733 (rank : 7)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	65
SwissProt Accessions	Q07104	Gene names	Gdf3, Gdf-3, Vgr-2
Domain Architecture
Description	Growth/differentiation factor 3 precursor (GDF-3) (VG-1-related protein 2).

GDF2_MOUSE
θ value	5.62301e-10 (rank : 28)	NC score	0.821592 (rank : 34)
Query Neighborhood Hits	68	Target Neighborhood Hits	70	Shared Neighborhood Hits	65
SwissProt Accessions	Q9WV56, Q9QZE0	Gene names	Gdf2, Bmp9
Domain Architecture
Description	Growth/differentiation factor 2 precursor (GDF-2) (Bone morphogenetic protein 9) (BMP-9).

GDF1_MOUSE
θ value	7.34386e-10 (rank : 29)	NC score	0.856238 (rank : 6)
Query Neighborhood Hits	68	Target Neighborhood Hits	71	Shared Neighborhood Hits	65
SwissProt Accessions	P20863	Gene names	Gdf1, Gdf-1
Domain Architecture
Description	Embryonic growth/differentiation factor 1 precursor (GDF-1).

GDF3_HUMAN
θ value	9.59137e-10 (rank : 30)	NC score	0.851800 (rank : 10)
Query Neighborhood Hits	68	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NR23, Q8NEJ4	Gene names	GDF3
Domain Architecture
Description	Growth/differentiation factor 3 precursor (GDF-3).

TGFB2_HUMAN
θ value	1.63604e-09 (rank : 31)	NC score	0.766639 (rank : 55)
Query Neighborhood Hits	68	Target Neighborhood Hits	67	Shared Neighborhood Hits	64
SwissProt Accessions	P61812, P08112, Q15579, Q15581, Q4VAV9	Gene names	TGFB2
Domain Architecture
Description	Transforming growth factor beta-2 precursor (TGF-beta-2) (Glioblastoma-derived T-cell suppressor factor) (G-TSF) (BSC-1 cell growth inhibitor) (Polyergin) (Cetermin).

TGFB2_MOUSE
θ value	1.63604e-09 (rank : 32)	NC score	0.772950 (rank : 52)
Query Neighborhood Hits	68	Target Neighborhood Hits	70	Shared Neighborhood Hits	65
SwissProt Accessions	P27090	Gene names	Tgfb2
Domain Architecture
Description	Transforming growth factor beta-2 precursor (TGF-beta-2).

BMP15_HUMAN
θ value	3.64472e-09 (rank : 33)	NC score	0.837889 (rank : 26)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	65
SwissProt Accessions	O95972, Q5JST1, Q9UMS1	Gene names	BMP15, GDF9B
Domain Architecture
Description	Bone morphogenetic protein 15 precursor (BMP-15) (Growth/differentiation factor 9B) (GDF-9B).

BMP4_HUMAN
θ value	4.76016e-09 (rank : 34)	NC score	0.836918 (rank : 29)
Query Neighborhood Hits	68	Target Neighborhood Hits	72	Shared Neighborhood Hits	66
SwissProt Accessions	P12644, Q9UM80	Gene names	BMP4, BMP2B, DVR4
Domain Architecture
Description	Bone morphogenetic protein 4 precursor (BMP-4) (BMP-2B).

TGFB3_HUMAN
θ value	6.21693e-09 (rank : 35)	NC score	0.770445 (rank : 53)
Query Neighborhood Hits	68	Target Neighborhood Hits	67	Shared Neighborhood Hits	65
SwissProt Accessions	P10600	Gene names	TGFB3
Domain Architecture
Description	Transforming growth factor beta-3 precursor (TGF-beta-3).

BMP3_MOUSE
θ value	8.11959e-09 (rank : 36)	NC score	0.818183 (rank : 36)
Query Neighborhood Hits	68	Target Neighborhood Hits	82	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BHE5	Gene names	Bmp3
Domain Architecture	No domain graphic available
Description	Bone morphogenetic protein 3 precursor (BMP-3).

BMP4_MOUSE
θ value	8.11959e-09 (rank : 37)	NC score	0.837753 (rank : 27)
Query Neighborhood Hits	68	Target Neighborhood Hits	71	Shared Neighborhood Hits	66
SwissProt Accessions	P21275	Gene names	Bmp4, Bmp-4, Dvr-4
Domain Architecture
Description	Bone morphogenetic protein 4 precursor (BMP-4) (BMP-2B).

BMP3B_MOUSE
θ value	1.80886e-08 (rank : 38)	NC score	0.809279 (rank : 41)
Query Neighborhood Hits	68	Target Neighborhood Hits	80	Shared Neighborhood Hits	64
SwissProt Accessions	P97737	Gene names	Gdf10, Bmp3b
Domain Architecture
Description	Bone morphogenetic protein 3b precursor (BMP-3b) (Growth/differentiation factor 10) (GDF-10).

BMP3_HUMAN
θ value	1.80886e-08 (rank : 39)	NC score	0.820999 (rank : 35)
Query Neighborhood Hits	68	Target Neighborhood Hits	85	Shared Neighborhood Hits	64
SwissProt Accessions	P12645	Gene names	BMP3
Domain Architecture
Description	Bone morphogenetic protein 3 precursor (BMP-3) (Osteogenin) (BMP-3A).

BMP3B_HUMAN
θ value	2.36244e-08 (rank : 40)	NC score	0.808441 (rank : 42)
Query Neighborhood Hits	68	Target Neighborhood Hits	90	Shared Neighborhood Hits	64
SwissProt Accessions	P55107, Q9UCX6	Gene names	GDF10, BMP3B
Domain Architecture
Description	Bone morphogenetic protein 3b precursor (BMP-3b) (Growth/differentiation factor 10) (GDF-10) (Bone-inducing protein) (BIP).

TGFB1_HUMAN
θ value	3.08544e-08 (rank : 41)	NC score	0.740505 (rank : 56)
Query Neighborhood Hits	68	Target Neighborhood Hits	64	Shared Neighborhood Hits	64
SwissProt Accessions	P01137, Q9UCG4	Gene names	TGFB1, TGFB
Domain Architecture
Description	Transforming growth factor beta-1 precursor (TGF-beta-1) [Contains: Latency-associated peptide (LAP)].

TGFB3_MOUSE
θ value	3.08544e-08 (rank : 42)	NC score	0.769436 (rank : 54)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	65
SwissProt Accessions	P17125	Gene names	Tgfb3
Domain Architecture
Description	Transforming growth factor beta-3 precursor (TGF-beta-3).

BMP8B_MOUSE
θ value	4.0297e-08 (rank : 43)	NC score	0.824759 (rank : 33)
Query Neighborhood Hits	68	Target Neighborhood Hits	70	Shared Neighborhood Hits	65
SwissProt Accessions	P55105	Gene names	Bmp8b
Domain Architecture
Description	Bone morphogenetic protein 8B precursor (BMP-8B).

TGFB1_MOUSE
θ value	8.97725e-08 (rank : 44)	NC score	0.738651 (rank : 57)
Query Neighborhood Hits	68	Target Neighborhood Hits	64	Shared Neighborhood Hits	64
SwissProt Accessions	P04202	Gene names	Tgfb1
Domain Architecture
Description	Transforming growth factor beta-1 precursor (TGF-beta-1) [Contains: Latency-associated peptide (LAP)].

BMP2_HUMAN
θ value	1.17247e-07 (rank : 45)	NC score	0.836446 (rank : 30)
Query Neighborhood Hits	68	Target Neighborhood Hits	74	Shared Neighborhood Hits	65
SwissProt Accessions	P12643	Gene names	BMP2, BMP2A
Domain Architecture
Description	Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A).

BMP2_MOUSE
θ value	1.17247e-07 (rank : 46)	NC score	0.837234 (rank : 28)
Query Neighborhood Hits	68	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	P21274	Gene names	Bmp2, Bmp-2
Domain Architecture
Description	Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A).

INHBC_HUMAN
θ value	2.61198e-07 (rank : 47)	NC score	0.800208 (rank : 46)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	65
SwissProt Accessions	P55103	Gene names	INHBC
Domain Architecture
Description	Inhibin beta C chain precursor (Activin beta-C chain).

INHBA_HUMAN
θ value	4.45536e-07 (rank : 48)	NC score	0.805761 (rank : 44)
Query Neighborhood Hits	68	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	P08476, Q14599	Gene names	INHBA
Domain Architecture
Description	Inhibin beta A chain precursor (Activin beta-A chain) (Erythroid differentiation protein) (EDF).

INHBA_MOUSE
θ value	4.45536e-07 (rank : 49)	NC score	0.806665 (rank : 43)
Query Neighborhood Hits	68	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	Q04998	Gene names	Inhba
Domain Architecture
Description	Inhibin beta A chain precursor (Activin beta-A chain).

GDF11_HUMAN
θ value	9.92553e-07 (rank : 50)	NC score	0.779606 (rank : 51)
Query Neighborhood Hits	68	Target Neighborhood Hits	73	Shared Neighborhood Hits	66
SwissProt Accessions	O95390, Q9UID1, Q9UID2	Gene names	GDF11, BMP11
Domain Architecture
Description	Growth/differentiation factor 11 precursor (GDF-11) (Bone morphogenetic protein 11).

GDF11_MOUSE
θ value	9.92553e-07 (rank : 51)	NC score	0.780350 (rank : 50)
Query Neighborhood Hits	68	Target Neighborhood Hits	73	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z1W4, Q9QX55, Q9R221	Gene names	Gdf11, Bmp11
Domain Architecture
Description	Growth/differentiation factor 11 precursor (GDF-11) (Bone morphogenetic protein 11).

INHBC_MOUSE
θ value	1.69304e-06 (rank : 52)	NC score	0.802134 (rank : 45)
Query Neighborhood Hits	68	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	P55104, Q61452	Gene names	Inhbc
Domain Architecture
Description	Inhibin beta C chain precursor (Activin beta-C chain).

GDF8_HUMAN
θ value	2.88788e-06 (rank : 53)	NC score	0.782635 (rank : 49)
Query Neighborhood Hits	68	Target Neighborhood Hits	71	Shared Neighborhood Hits	66
SwissProt Accessions	O14793, Q6B0H2	Gene names	GDF8, MSTN
Domain Architecture
Description	Growth/differentiation factor 8 precursor (GDF-8) (Myostatin).

GDF8_MOUSE
θ value	2.88788e-06 (rank : 54)	NC score	0.782943 (rank : 48)
Query Neighborhood Hits	68	Target Neighborhood Hits	71	Shared Neighborhood Hits	66
SwissProt Accessions	O08689	Gene names	Gdf8, Mstn
Domain Architecture
Description	Growth/differentiation factor 8 precursor (GDF-8) (Myostatin).

INHBB_HUMAN
θ value	4.1701e-05 (rank : 55)	NC score	0.795794 (rank : 47)
Query Neighborhood Hits	68	Target Neighborhood Hits	70	Shared Neighborhood Hits	66
SwissProt Accessions	P09529, Q8N1D3	Gene names	INHBB
Domain Architecture
Description	Inhibin beta B chain precursor (Activin beta-B chain).

BMP10_HUMAN
θ value	7.1131e-05 (rank : 56)	NC score	0.810879 (rank : 38)
Query Neighborhood Hits	68	Target Neighborhood Hits	72	Shared Neighborhood Hits	65
SwissProt Accessions	O95393	Gene names	BMP10
Domain Architecture
Description	Bone morphogenetic protein 10 precursor (BMP-10).

BMP10_MOUSE
θ value	7.1131e-05 (rank : 57)	NC score	0.809407 (rank : 40)
Query Neighborhood Hits	68	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	Q9R229, Q9Z1V8	Gene names	Bmp10
Domain Architecture
Description	Bone morphogenetic protein 10 precursor (BMP-10).

MIS_MOUSE
θ value	0.00020696 (rank : 58)	NC score	0.525764 (rank : 60)
Query Neighborhood Hits	68	Target Neighborhood Hits	86	Shared Neighborhood Hits	59
SwissProt Accessions	P27106	Gene names	Amh
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

LEFTB_HUMAN
θ value	0.000461057 (rank : 59)	NC score	0.430467 (rank : 63)
Query Neighborhood Hits	68	Target Neighborhood Hits	63	Shared Neighborhood Hits	60
SwissProt Accessions	O75610	Gene names	LEFTB, LEFTYB
Domain Architecture
Description	Left-right determination factor B precursor (Lefty-B protein).

INHA_HUMAN
θ value	0.00175202 (rank : 60)	NC score	0.642289 (rank : 58)
Query Neighborhood Hits	68	Target Neighborhood Hits	66	Shared Neighborhood Hits	63
SwissProt Accessions	P05111	Gene names	INHA
Domain Architecture
Description	Inhibin alpha chain precursor.

TGFB4_HUMAN
θ value	0.00175202 (rank : 61)	NC score	0.437835 (rank : 62)
Query Neighborhood Hits	68	Target Neighborhood Hits	60	Shared Neighborhood Hits	59
SwissProt Accessions	O00292, O75611, Q8NBQ9	Gene names	EBAF, LEFTA, LEFTYA, TGFB4
Domain Architecture
Description	Transforming growth factor beta-4 precursor (TGF-beta-4) (Endometrial bleeding-associated factor) (Left-right determination factor A) (Lefty-A protein).

NRTN_HUMAN
θ value	0.0148317 (rank : 62)	NC score	0.071603 (rank : 67)
Query Neighborhood Hits	68	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q99748	Gene names	NRTN
Domain Architecture
Description	Neurturin precursor.

MIS_HUMAN
θ value	0.0193708 (rank : 63)	NC score	0.505807 (rank : 61)
Query Neighborhood Hits	68	Target Neighborhood Hits	87	Shared Neighborhood Hits	56
SwissProt Accessions	P03971, O75246	Gene names	AMH, MIF
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

TGFB4_MOUSE
θ value	0.0961366 (rank : 64)	NC score	0.405663 (rank : 64)
Query Neighborhood Hits	68	Target Neighborhood Hits	59	Shared Neighborhood Hits	57
SwissProt Accessions	Q64280	Gene names	Ebaf, Lefty, Lefty1, Stra3, Tgfb4
Domain Architecture
Description	Transforming growth factor beta-4 precursor (TGF-beta-4) (Lefty protein) (Lefty-1 protein) (STRA3 protein).

INHA_MOUSE
θ value	0.279714 (rank : 65)	NC score	0.623647 (rank : 59)
Query Neighborhood Hits	68	Target Neighborhood Hits	66	Shared Neighborhood Hits	61
SwissProt Accessions	Q04997	Gene names	Inha
Domain Architecture
Description	Inhibin alpha chain precursor.

LEFTB_MOUSE
θ value	0.279714 (rank : 66)	NC score	0.402332 (rank : 65)
Query Neighborhood Hits	68	Target Neighborhood Hits	58	Shared Neighborhood Hits	57
SwissProt Accessions	P57785	Gene names	Leftb, Lefty2
Domain Architecture	No domain graphic available
Description	Left-right determination factor B precursor (Lefty-2 protein).

PSPN_MOUSE
θ value	1.06291 (rank : 67)	NC score	0.096623 (rank : 66)
Query Neighborhood Hits	68	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	O70300	Gene names	Pspn
Domain Architecture
Description	Persephin precursor (PSP).

TRIB3_HUMAN
θ value	5.27518 (rank : 68)	NC score	-0.001271 (rank : 69)
Query Neighborhood Hits	68	Target Neighborhood Hits	519	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RU7, Q53GU4, Q53ZW7, Q6I9Y9, Q8TAI6, Q9H5M8, Q9NUD2	Gene names	TRIB3, C20orf97, NIPK, SKIP3, TRB3
Domain Architecture
Description	Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (p65-interacting inhibitor of NF-kappaB) (SINK).

PSPN_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.068602 (rank : 68)
Query Neighborhood Hits	68	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	O60542	Gene names	PSPN
Domain Architecture
Description	Persephin precursor (PSP).

Hits sorted by NC score

GDF15_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.25536e-168 (rank : 1)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	68
SwissProt Accessions	Q99988, O14629, P78360, Q9NRT0	Gene names	GDF15, MIC1, PDF, PLAB, PTGFB
Domain Architecture
Description	Growth/differentiation factor 15 precursor (GDF-15) (Placental bone morphogenetic protein) (Placental TGF-beta) (Macrophage inhibitory cytokine 1) (MIC-1) (Prostate differentiation factor) (NSAID-regulated protein 1) (NRG-1).

GDF15_MOUSE
NC score	0.985663 (rank : 2)	θ value	1.03614e-88 (rank : 2)
Query Neighborhood Hits	68	Target Neighborhood Hits	71	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0J7	Gene names	Gdf15, Sbf
Domain Architecture
Description	Growth/differentiation factor 15 precursor (GDF-15).

GDF1_HUMAN
NC score	0.868418 (rank : 3)	θ value	2.69671e-12 (rank : 12)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	65
SwissProt Accessions	P27539, O43344	Gene names	GDF1
Domain Architecture
Description	Embryonic growth/differentiation factor 1 precursor (GDF-1).

GDF7_MOUSE
NC score	0.864948 (rank : 4)	θ value	2.0648e-12 (rank : 11)
Query Neighborhood Hits	68	Target Neighborhood Hits	70	Shared Neighborhood Hits	65
SwissProt Accessions	P43029, Q7TNX4, Q99MY1	Gene names	Gdf7, Gdf-7
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 7 precursor (GDF-7).

GDF7_HUMAN
NC score	0.863777 (rank : 5)	θ value	4.59992e-12 (rank : 13)
Query Neighborhood Hits	68	Target Neighborhood Hits	66	Shared Neighborhood Hits	65
SwissProt Accessions	Q7Z4P5	Gene names	GDF7
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 7 precursor (GDF-7).

GDF1_MOUSE
NC score	0.856238 (rank : 6)	θ value	7.34386e-10 (rank : 29)
Query Neighborhood Hits	68	Target Neighborhood Hits	71	Shared Neighborhood Hits	65
SwissProt Accessions	P20863	Gene names	Gdf1, Gdf-1
Domain Architecture
Description	Embryonic growth/differentiation factor 1 precursor (GDF-1).

GDF3_MOUSE
NC score	0.855733 (rank : 7)	θ value	3.29651e-10 (rank : 27)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	65
SwissProt Accessions	Q07104	Gene names	Gdf3, Gdf-3, Vgr-2
Domain Architecture
Description	Growth/differentiation factor 3 precursor (GDF-3) (VG-1-related protein 2).

BMP6_HUMAN
NC score	0.854661 (rank : 8)	θ value	6.41864e-14 (rank : 4)
Query Neighborhood Hits	68	Target Neighborhood Hits	82	Shared Neighborhood Hits	65
SwissProt Accessions	P22004	Gene names	BMP6, VGR
Domain Architecture
Description	Bone morphogenetic protein 6 precursor (BMP-6).

BMP6_MOUSE
NC score	0.853364 (rank : 9)	θ value	1.42992e-13 (rank : 7)
Query Neighborhood Hits	68	Target Neighborhood Hits	84	Shared Neighborhood Hits	65
SwissProt Accessions	P20722	Gene names	Bmp6, Bmp-6, Vgr1
Domain Architecture
Description	Bone morphogenetic protein 6 precursor (BMP-6) (VG-1-related protein) (VGR-1).

GDF3_HUMAN
NC score	0.851800 (rank : 10)	θ value	9.59137e-10 (rank : 30)
Query Neighborhood Hits	68	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NR23, Q8NEJ4	Gene names	GDF3
Domain Architecture
Description	Growth/differentiation factor 3 precursor (GDF-3).

NODAL_HUMAN
NC score	0.851774 (rank : 11)	θ value	1.74796e-11 (rank : 20)
Query Neighborhood Hits	68	Target Neighborhood Hits	66	Shared Neighborhood Hits	63
SwissProt Accessions	Q96S42, Q2M3A5, Q8N4V3	Gene names	NODAL
Domain Architecture
Description	Nodal homolog precursor.

BMP7_MOUSE
NC score	0.850094 (rank : 12)	θ value	4.91457e-14 (rank : 3)
Query Neighborhood Hits	68	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	P23359, Q91XF7	Gene names	Bmp7, Bmp-7, Op1
Domain Architecture
Description	Bone morphogenetic protein 7 precursor (BMP-7) (Osteogenic protein 1) (OP-1).

NODAL_MOUSE
NC score	0.849961 (rank : 13)	θ value	5.08577e-11 (rank : 23)
Query Neighborhood Hits	68	Target Neighborhood Hits	66	Shared Neighborhood Hits	63
SwissProt Accessions	P43021	Gene names	Nodal
Domain Architecture
Description	Nodal precursor.

BMP7_HUMAN
NC score	0.848879 (rank : 14)	θ value	1.42992e-13 (rank : 8)
Query Neighborhood Hits	68	Target Neighborhood Hits	67	Shared Neighborhood Hits	65
SwissProt Accessions	P18075, Q9H512, Q9NTQ7	Gene names	BMP7, OP1
Domain Architecture
Description	Bone morphogenetic protein 7 precursor (BMP-7) (Osteogenic protein 1) (OP-1) (Eptotermin alfa).

GDF6_HUMAN
NC score	0.848206 (rank : 15)	θ value	1.9326e-10 (rank : 25)
Query Neighborhood Hits	68	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	Q6KF10, Q6PI58	Gene names	GDF6, GDF16
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 6 precursor (GDF-6) (Growth/differentiation factor 16).

GDF6_MOUSE
NC score	0.847114 (rank : 16)	θ value	1.9326e-10 (rank : 26)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	65
SwissProt Accessions	P43028, Q70UT4	Gene names	Gdf6, Gdf-6, Gdf16
Domain Architecture	No domain graphic available
Description	Growth/differentiation factor 6 precursor (GDF-6) (Growth/differentiation factor 16).

BMP5_MOUSE
NC score	0.845789 (rank : 17)	θ value	1.42992e-13 (rank : 6)
Query Neighborhood Hits	68	Target Neighborhood Hits	72	Shared Neighborhood Hits	65
SwissProt Accessions	P49003	Gene names	Bmp5, Bmp-5
Domain Architecture
Description	Bone morphogenetic protein 5 precursor (BMP-5).

BMP5_HUMAN
NC score	0.845754 (rank : 18)	θ value	1.42992e-13 (rank : 5)
Query Neighborhood Hits	68	Target Neighborhood Hits	72	Shared Neighborhood Hits	65
SwissProt Accessions	P22003, Q9H547, Q9NTM5	Gene names	BMP5
Domain Architecture
Description	Bone morphogenetic protein 5 precursor (BMP-5).

BMP8B_HUMAN
NC score	0.844379 (rank : 19)	θ value	2.0648e-12 (rank : 10)
Query Neighborhood Hits	68	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	P34820, Q53ZM7, Q9NUF0	Gene names	BMP8B, BMP8
Domain Architecture
Description	Bone morphogenetic protein 8B precursor (BMP-8B) (BMP-8) (Osteogenic protein 2) (OP-2).

GDF5_HUMAN
NC score	0.843915 (rank : 20)	θ value	2.28291e-11 (rank : 21)
Query Neighborhood Hits	68	Target Neighborhood Hits	103	Shared Neighborhood Hits	65
SwissProt Accessions	P43026, Q96SB1	Gene names	GDF5, CDMP1
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Radotermin).

BMP8A_HUMAN
NC score	0.843863 (rank : 21)	θ value	2.0648e-12 (rank : 9)
Query Neighborhood Hits	68	Target Neighborhood Hits	66	Shared Neighborhood Hits	65
SwissProt Accessions	Q7Z5Y6, Q5T3A5	Gene names	BMP8A
Domain Architecture	No domain graphic available
Description	Bone morphogenetic protein 8A precursor (BMP-8A).

GDF5_MOUSE
NC score	0.843320 (rank : 22)	θ value	2.98157e-11 (rank : 22)
Query Neighborhood Hits	68	Target Neighborhood Hits	99	Shared Neighborhood Hits	65
SwissProt Accessions	P43027	Gene names	Gdf5, Bp, Gdf-5
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5).

INHBE_HUMAN
NC score	0.841343 (rank : 23)	θ value	4.59992e-12 (rank : 14)
Query Neighborhood Hits	68	Target Neighborhood Hits	69	Shared Neighborhood Hits	65
SwissProt Accessions	P58166	Gene names	INHBE
Domain Architecture
Description	Inhibin beta E chain precursor (Activin beta-E chain).

BMP8A_MOUSE
NC score	0.840938 (rank : 24)	θ value	6.00763e-12 (rank : 16)
Query Neighborhood Hits	68	Target Neighborhood Hits	67	Shared Neighborhood Hits	65
SwissProt Accessions	P34821	Gene names	Bmp8a, Bmp-8, Bmp8
Domain Architecture
Description	Bone morphogenetic protein 8A precursor (BMP-8A) (Osteogenic protein 2) (OP-2).

INHBE_MOUSE
NC score	0.840849 (rank : 25)	θ value	4.59992e-12 (rank : 15)
Query Neighborhood Hits	68	Target Neighborhood Hits	69	Shared Neighborhood Hits	65
SwissProt Accessions	O08717	Gene names	Inhbe
Domain Architecture
Description	Inhibin beta E chain precursor (Activin beta-E chain).

BMP15_HUMAN
NC score	0.837889 (rank : 26)	θ value	3.64472e-09 (rank : 33)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	65
SwissProt Accessions	O95972, Q5JST1, Q9UMS1	Gene names	BMP15, GDF9B
Domain Architecture
Description	Bone morphogenetic protein 15 precursor (BMP-15) (Growth/differentiation factor 9B) (GDF-9B).

BMP4_MOUSE
NC score	0.837753 (rank : 27)	θ value	8.11959e-09 (rank : 37)
Query Neighborhood Hits	68	Target Neighborhood Hits	71	Shared Neighborhood Hits	66
SwissProt Accessions	P21275	Gene names	Bmp4, Bmp-4, Dvr-4
Domain Architecture
Description	Bone morphogenetic protein 4 precursor (BMP-4) (BMP-2B).

BMP2_MOUSE
NC score	0.837234 (rank : 28)	θ value	1.17247e-07 (rank : 46)
Query Neighborhood Hits	68	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	P21274	Gene names	Bmp2, Bmp-2
Domain Architecture
Description	Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A).

BMP4_HUMAN
NC score	0.836918 (rank : 29)	θ value	4.76016e-09 (rank : 34)
Query Neighborhood Hits	68	Target Neighborhood Hits	72	Shared Neighborhood Hits	66
SwissProt Accessions	P12644, Q9UM80	Gene names	BMP4, BMP2B, DVR4
Domain Architecture
Description	Bone morphogenetic protein 4 precursor (BMP-4) (BMP-2B).

BMP2_HUMAN
NC score	0.836446 (rank : 30)	θ value	1.17247e-07 (rank : 45)
Query Neighborhood Hits	68	Target Neighborhood Hits	74	Shared Neighborhood Hits	65
SwissProt Accessions	P12643	Gene names	BMP2, BMP2A
Domain Architecture
Description	Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A).

BMP15_MOUSE
NC score	0.833008 (rank : 31)	θ value	1.133e-10 (rank : 24)
Query Neighborhood Hits	68	Target Neighborhood Hits	64	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z0L4, Q3UT46	Gene names	Bmp15, Gdf9b
Domain Architecture
Description	Bone morphogenetic protein 15 precursor (BMP-15) (Growth/differentiation factor 9B) (GDF-9B).

GDF2_HUMAN
NC score	0.827809 (rank : 32)	θ value	1.74796e-11 (rank : 19)
Query Neighborhood Hits	68	Target Neighborhood Hits	77	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UK05, Q9Y571	Gene names	GDF2, BMP9
Domain Architecture
Description	Growth/differentiation factor 2 precursor (GDF-2) (Bone morphogenetic protein 9) (BMP-9).

BMP8B_MOUSE
NC score	0.824759 (rank : 33)	θ value	4.0297e-08 (rank : 43)
Query Neighborhood Hits	68	Target Neighborhood Hits	70	Shared Neighborhood Hits	65
SwissProt Accessions	P55105	Gene names	Bmp8b
Domain Architecture
Description	Bone morphogenetic protein 8B precursor (BMP-8B).

GDF2_MOUSE
NC score	0.821592 (rank : 34)	θ value	5.62301e-10 (rank : 28)
Query Neighborhood Hits	68	Target Neighborhood Hits	70	Shared Neighborhood Hits	65
SwissProt Accessions	Q9WV56, Q9QZE0	Gene names	Gdf2, Bmp9
Domain Architecture
Description	Growth/differentiation factor 2 precursor (GDF-2) (Bone morphogenetic protein 9) (BMP-9).

BMP3_HUMAN
NC score	0.820999 (rank : 35)	θ value	1.80886e-08 (rank : 39)
Query Neighborhood Hits	68	Target Neighborhood Hits	85	Shared Neighborhood Hits	64
SwissProt Accessions	P12645	Gene names	BMP3
Domain Architecture
Description	Bone morphogenetic protein 3 precursor (BMP-3) (Osteogenin) (BMP-3A).

BMP3_MOUSE
NC score	0.818183 (rank : 36)	θ value	8.11959e-09 (rank : 36)
Query Neighborhood Hits	68	Target Neighborhood Hits	82	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BHE5	Gene names	Bmp3
Domain Architecture	No domain graphic available
Description	Bone morphogenetic protein 3 precursor (BMP-3).

GDF9_MOUSE
NC score	0.813915 (rank : 37)	θ value	6.00763e-12 (rank : 17)
Query Neighborhood Hits	68	Target Neighborhood Hits	63	Shared Neighborhood Hits	59
SwissProt Accessions	Q07105	Gene names	Gdf9, Gdf-9
Domain Architecture
Description	Growth/differentiation factor 9 precursor (GDF-9).

BMP10_HUMAN
NC score	0.810879 (rank : 38)	θ value	7.1131e-05 (rank : 56)
Query Neighborhood Hits	68	Target Neighborhood Hits	72	Shared Neighborhood Hits	65
SwissProt Accessions	O95393	Gene names	BMP10
Domain Architecture
Description	Bone morphogenetic protein 10 precursor (BMP-10).

GDF9_HUMAN
NC score	0.810097 (rank : 39)	θ value	1.02475e-11 (rank : 18)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	59
SwissProt Accessions	O60383	Gene names	GDF9
Domain Architecture
Description	Growth/differentiation factor 9 precursor (GDF-9).

BMP10_MOUSE
NC score	0.809407 (rank : 40)	θ value	7.1131e-05 (rank : 57)
Query Neighborhood Hits	68	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	Q9R229, Q9Z1V8	Gene names	Bmp10
Domain Architecture
Description	Bone morphogenetic protein 10 precursor (BMP-10).

BMP3B_MOUSE
NC score	0.809279 (rank : 41)	θ value	1.80886e-08 (rank : 38)
Query Neighborhood Hits	68	Target Neighborhood Hits	80	Shared Neighborhood Hits	64
SwissProt Accessions	P97737	Gene names	Gdf10, Bmp3b
Domain Architecture
Description	Bone morphogenetic protein 3b precursor (BMP-3b) (Growth/differentiation factor 10) (GDF-10).

BMP3B_HUMAN
NC score	0.808441 (rank : 42)	θ value	2.36244e-08 (rank : 40)
Query Neighborhood Hits	68	Target Neighborhood Hits	90	Shared Neighborhood Hits	64
SwissProt Accessions	P55107, Q9UCX6	Gene names	GDF10, BMP3B
Domain Architecture
Description	Bone morphogenetic protein 3b precursor (BMP-3b) (Growth/differentiation factor 10) (GDF-10) (Bone-inducing protein) (BIP).

INHBA_MOUSE
NC score	0.806665 (rank : 43)	θ value	4.45536e-07 (rank : 49)
Query Neighborhood Hits	68	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	Q04998	Gene names	Inhba
Domain Architecture
Description	Inhibin beta A chain precursor (Activin beta-A chain).

INHBA_HUMAN
NC score	0.805761 (rank : 44)	θ value	4.45536e-07 (rank : 48)
Query Neighborhood Hits	68	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	P08476, Q14599	Gene names	INHBA
Domain Architecture
Description	Inhibin beta A chain precursor (Activin beta-A chain) (Erythroid differentiation protein) (EDF).

INHBC_MOUSE
NC score	0.802134 (rank : 45)	θ value	1.69304e-06 (rank : 52)
Query Neighborhood Hits	68	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	P55104, Q61452	Gene names	Inhbc
Domain Architecture
Description	Inhibin beta C chain precursor (Activin beta-C chain).

INHBC_HUMAN
NC score	0.800208 (rank : 46)	θ value	2.61198e-07 (rank : 47)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	65
SwissProt Accessions	P55103	Gene names	INHBC
Domain Architecture
Description	Inhibin beta C chain precursor (Activin beta-C chain).

INHBB_HUMAN
NC score	0.795794 (rank : 47)	θ value	4.1701e-05 (rank : 55)
Query Neighborhood Hits	68	Target Neighborhood Hits	70	Shared Neighborhood Hits	66
SwissProt Accessions	P09529, Q8N1D3	Gene names	INHBB
Domain Architecture
Description	Inhibin beta B chain precursor (Activin beta-B chain).

GDF8_MOUSE
NC score	0.782943 (rank : 48)	θ value	2.88788e-06 (rank : 54)
Query Neighborhood Hits	68	Target Neighborhood Hits	71	Shared Neighborhood Hits	66
SwissProt Accessions	O08689	Gene names	Gdf8, Mstn
Domain Architecture
Description	Growth/differentiation factor 8 precursor (GDF-8) (Myostatin).

GDF8_HUMAN
NC score	0.782635 (rank : 49)	θ value	2.88788e-06 (rank : 53)
Query Neighborhood Hits	68	Target Neighborhood Hits	71	Shared Neighborhood Hits	66
SwissProt Accessions	O14793, Q6B0H2	Gene names	GDF8, MSTN
Domain Architecture
Description	Growth/differentiation factor 8 precursor (GDF-8) (Myostatin).

GDF11_MOUSE
NC score	0.780350 (rank : 50)	θ value	9.92553e-07 (rank : 51)
Query Neighborhood Hits	68	Target Neighborhood Hits	73	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z1W4, Q9QX55, Q9R221	Gene names	Gdf11, Bmp11
Domain Architecture
Description	Growth/differentiation factor 11 precursor (GDF-11) (Bone morphogenetic protein 11).

GDF11_HUMAN
NC score	0.779606 (rank : 51)	θ value	9.92553e-07 (rank : 50)
Query Neighborhood Hits	68	Target Neighborhood Hits	73	Shared Neighborhood Hits	66
SwissProt Accessions	O95390, Q9UID1, Q9UID2	Gene names	GDF11, BMP11
Domain Architecture
Description	Growth/differentiation factor 11 precursor (GDF-11) (Bone morphogenetic protein 11).

TGFB2_MOUSE
NC score	0.772950 (rank : 52)	θ value	1.63604e-09 (rank : 32)
Query Neighborhood Hits	68	Target Neighborhood Hits	70	Shared Neighborhood Hits	65
SwissProt Accessions	P27090	Gene names	Tgfb2
Domain Architecture
Description	Transforming growth factor beta-2 precursor (TGF-beta-2).

TGFB3_HUMAN
NC score	0.770445 (rank : 53)	θ value	6.21693e-09 (rank : 35)
Query Neighborhood Hits	68	Target Neighborhood Hits	67	Shared Neighborhood Hits	65
SwissProt Accessions	P10600	Gene names	TGFB3
Domain Architecture
Description	Transforming growth factor beta-3 precursor (TGF-beta-3).

TGFB3_MOUSE
NC score	0.769436 (rank : 54)	θ value	3.08544e-08 (rank : 42)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	65
SwissProt Accessions	P17125	Gene names	Tgfb3
Domain Architecture
Description	Transforming growth factor beta-3 precursor (TGF-beta-3).

TGFB2_HUMAN
NC score	0.766639 (rank : 55)	θ value	1.63604e-09 (rank : 31)
Query Neighborhood Hits	68	Target Neighborhood Hits	67	Shared Neighborhood Hits	64
SwissProt Accessions	P61812, P08112, Q15579, Q15581, Q4VAV9	Gene names	TGFB2
Domain Architecture
Description	Transforming growth factor beta-2 precursor (TGF-beta-2) (Glioblastoma-derived T-cell suppressor factor) (G-TSF) (BSC-1 cell growth inhibitor) (Polyergin) (Cetermin).

TGFB1_HUMAN
NC score	0.740505 (rank : 56)	θ value	3.08544e-08 (rank : 41)
Query Neighborhood Hits	68	Target Neighborhood Hits	64	Shared Neighborhood Hits	64
SwissProt Accessions	P01137, Q9UCG4	Gene names	TGFB1, TGFB
Domain Architecture
Description	Transforming growth factor beta-1 precursor (TGF-beta-1) [Contains: Latency-associated peptide (LAP)].

TGFB1_MOUSE
NC score	0.738651 (rank : 57)	θ value	8.97725e-08 (rank : 44)
Query Neighborhood Hits	68	Target Neighborhood Hits	64	Shared Neighborhood Hits	64
SwissProt Accessions	P04202	Gene names	Tgfb1
Domain Architecture
Description	Transforming growth factor beta-1 precursor (TGF-beta-1) [Contains: Latency-associated peptide (LAP)].

INHA_HUMAN
NC score	0.642289 (rank : 58)	θ value	0.00175202 (rank : 60)
Query Neighborhood Hits	68	Target Neighborhood Hits	66	Shared Neighborhood Hits	63
SwissProt Accessions	P05111	Gene names	INHA
Domain Architecture
Description	Inhibin alpha chain precursor.

INHA_MOUSE
NC score	0.623647 (rank : 59)	θ value	0.279714 (rank : 65)
Query Neighborhood Hits	68	Target Neighborhood Hits	66	Shared Neighborhood Hits	61
SwissProt Accessions	Q04997	Gene names	Inha
Domain Architecture
Description	Inhibin alpha chain precursor.

MIS_MOUSE
NC score	0.525764 (rank : 60)	θ value	0.00020696 (rank : 58)
Query Neighborhood Hits	68	Target Neighborhood Hits	86	Shared Neighborhood Hits	59
SwissProt Accessions	P27106	Gene names	Amh
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

MIS_HUMAN
NC score	0.505807 (rank : 61)	θ value	0.0193708 (rank : 63)
Query Neighborhood Hits	68	Target Neighborhood Hits	87	Shared Neighborhood Hits	56
SwissProt Accessions	P03971, O75246	Gene names	AMH, MIF
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

TGFB4_HUMAN
NC score	0.437835 (rank : 62)	θ value	0.00175202 (rank : 61)
Query Neighborhood Hits	68	Target Neighborhood Hits	60	Shared Neighborhood Hits	59
SwissProt Accessions	O00292, O75611, Q8NBQ9	Gene names	EBAF, LEFTA, LEFTYA, TGFB4
Domain Architecture
Description	Transforming growth factor beta-4 precursor (TGF-beta-4) (Endometrial bleeding-associated factor) (Left-right determination factor A) (Lefty-A protein).

LEFTB_HUMAN
NC score	0.430467 (rank : 63)	θ value	0.000461057 (rank : 59)
Query Neighborhood Hits	68	Target Neighborhood Hits	63	Shared Neighborhood Hits	60
SwissProt Accessions	O75610	Gene names	LEFTB, LEFTYB
Domain Architecture
Description	Left-right determination factor B precursor (Lefty-B protein).

TGFB4_MOUSE
NC score	0.405663 (rank : 64)	θ value	0.0961366 (rank : 64)
Query Neighborhood Hits	68	Target Neighborhood Hits	59	Shared Neighborhood Hits	57
SwissProt Accessions	Q64280	Gene names	Ebaf, Lefty, Lefty1, Stra3, Tgfb4
Domain Architecture
Description	Transforming growth factor beta-4 precursor (TGF-beta-4) (Lefty protein) (Lefty-1 protein) (STRA3 protein).

LEFTB_MOUSE
NC score	0.402332 (rank : 65)	θ value	0.279714 (rank : 66)
Query Neighborhood Hits	68	Target Neighborhood Hits	58	Shared Neighborhood Hits	57
SwissProt Accessions	P57785	Gene names	Leftb, Lefty2
Domain Architecture	No domain graphic available
Description	Left-right determination factor B precursor (Lefty-2 protein).

PSPN_MOUSE
NC score	0.096623 (rank : 66)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	68	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	O70300	Gene names	Pspn
Domain Architecture
Description	Persephin precursor (PSP).

NRTN_HUMAN
NC score	0.071603 (rank : 67)	θ value	0.0148317 (rank : 62)
Query Neighborhood Hits	68	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q99748	Gene names	NRTN
Domain Architecture
Description	Neurturin precursor.

PSPN_HUMAN
NC score	0.068602 (rank : 68)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	68	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	O60542	Gene names	PSPN
Domain Architecture
Description	Persephin precursor (PSP).

TRIB3_HUMAN
NC score	-0.001271 (rank : 69)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	68	Target Neighborhood Hits	519	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RU7, Q53GU4, Q53ZW7, Q6I9Y9, Q8TAI6, Q9H5M8, Q9NUD2	Gene names	TRIB3, C20orf97, NIPK, SKIP3, TRB3
Domain Architecture
Description	Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (p65-interacting inhibitor of NF-kappaB) (SINK).