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Network neighborhood for query Sequence : PSPN_HUMAN

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PSPN_HUMAN
SwissProt Accessions	O60542	Gene names	PSPN
Domain Architecture
Description	Persephin precursor (PSP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PSPN_HUMAN
θ value	6.73165e-80 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	O60542	Gene names	PSPN
Domain Architecture
Description	Persephin precursor (PSP).

PSPN_MOUSE
θ value	9.81109e-47 (rank : 2)	NC score	0.971156 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	O70300	Gene names	Pspn
Domain Architecture
Description	Persephin precursor (PSP).

ARTN_HUMAN
θ value	2.97466e-19 (rank : 3)	NC score	0.843402 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	42	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T4W7, O95441, O96030, Q6P6A3	Gene names	ARTN, EVN
Domain Architecture	No domain graphic available
Description	Artemin precursor (Enovin) (Neublastin).

ARTN_MOUSE
θ value	8.65492e-19 (rank : 4)	NC score	0.841332 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0L2, Q3SXF4, Q3SXF5	Gene names	Artn
Domain Architecture	No domain graphic available
Description	Artemin precursor.

NRTN_HUMAN
θ value	2.13179e-17 (rank : 5)	NC score	0.842553 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q99748	Gene names	NRTN
Domain Architecture
Description	Neurturin precursor.

NRTN_MOUSE
θ value	2.13179e-17 (rank : 6)	NC score	0.851934 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P97463	Gene names	Nrtn
Domain Architecture
Description	Neurturin precursor.

GDNF_MOUSE
θ value	7.84624e-12 (rank : 7)	NC score	0.715722 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P48540, O09058, P70446, P97919, P97920	Gene names	Gdnf
Domain Architecture
Description	Glial cell line-derived neurotrophic factor precursor.

GDNF_HUMAN
θ value	2.28291e-11 (rank : 8)	NC score	0.714769 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P39905, Q96L44, Q9UD33, Q9UP97	Gene names	GDNF
Domain Architecture
Description	Glial cell line-derived neurotrophic factor precursor (Astrocyte- derived trophic factor 1) (ATF-1).

GDF15_MOUSE
θ value	0.0736092 (rank : 9)	NC score	0.091400 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	71	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0J7	Gene names	Gdf15, Sbf
Domain Architecture
Description	Growth/differentiation factor 15 precursor (GDF-15).

GDF11_HUMAN
θ value	0.125558 (rank : 10)	NC score	0.096908 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	73	Shared Neighborhood Hits	10
SwissProt Accessions	O95390, Q9UID1, Q9UID2	Gene names	GDF11, BMP11
Domain Architecture
Description	Growth/differentiation factor 11 precursor (GDF-11) (Bone morphogenetic protein 11).

GDF11_MOUSE
θ value	0.125558 (rank : 11)	NC score	0.096812 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	73	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1W4, Q9QX55, Q9R221	Gene names	Gdf11, Bmp11
Domain Architecture
Description	Growth/differentiation factor 11 precursor (GDF-11) (Bone morphogenetic protein 11).

GDF8_HUMAN
θ value	0.47712 (rank : 12)	NC score	0.091253 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	O14793, Q6B0H2	Gene names	GDF8, MSTN
Domain Architecture
Description	Growth/differentiation factor 8 precursor (GDF-8) (Myostatin).

GDF8_MOUSE
θ value	0.47712 (rank : 13)	NC score	0.091271 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	O08689	Gene names	Gdf8, Mstn
Domain Architecture
Description	Growth/differentiation factor 8 precursor (GDF-8) (Myostatin).

RTBDN_HUMAN
θ value	0.813845 (rank : 14)	NC score	0.075204 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BSG5, Q9BWT5	Gene names	RTBDN
Domain Architecture	No domain graphic available
Description	Retbindin precursor.

INHBB_HUMAN
θ value	2.36792 (rank : 15)	NC score	0.069351 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	P09529, Q8N1D3	Gene names	INHBB
Domain Architecture
Description	Inhibin beta B chain precursor (Activin beta-B chain).

INHBC_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.052858 (rank : 19)
Query Neighborhood Hits	17	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	P55103	Gene names	INHBC
Domain Architecture
Description	Inhibin beta C chain precursor (Activin beta-C chain).

GDF9_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.038245 (rank : 20)
Query Neighborhood Hits	17	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q07105	Gene names	Gdf9, Gdf-9
Domain Architecture
Description	Growth/differentiation factor 9 precursor (GDF-9).

GDF15_HUMAN
θ value	θ > 10 (rank : 18)	NC score	0.068602 (rank : 18)
Query Neighborhood Hits	17	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	Q99988, O14629, P78360, Q9NRT0	Gene names	GDF15, MIC1, PDF, PLAB, PTGFB
Domain Architecture
Description	Growth/differentiation factor 15 precursor (GDF-15) (Placental bone morphogenetic protein) (Placental TGF-beta) (Macrophage inhibitory cytokine 1) (MIC-1) (Prostate differentiation factor) (NSAID-regulated protein 1) (NRG-1).

MIS_HUMAN
θ value	θ > 10 (rank : 19)	NC score	0.110577 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	P03971, O75246	Gene names	AMH, MIF
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

MIS_MOUSE
θ value	θ > 10 (rank : 20)	NC score	0.100332 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	86	Shared Neighborhood Hits	12
SwissProt Accessions	P27106	Gene names	Amh
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

Hits sorted by NC score

PSPN_HUMAN
NC score	0.999962 (rank : 1)	θ value	6.73165e-80 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	O60542	Gene names	PSPN
Domain Architecture
Description	Persephin precursor (PSP).

PSPN_MOUSE
NC score	0.971156 (rank : 2)	θ value	9.81109e-47 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	O70300	Gene names	Pspn
Domain Architecture
Description	Persephin precursor (PSP).

NRTN_MOUSE
NC score	0.851934 (rank : 3)	θ value	2.13179e-17 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P97463	Gene names	Nrtn
Domain Architecture
Description	Neurturin precursor.

ARTN_HUMAN
NC score	0.843402 (rank : 4)	θ value	2.97466e-19 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	42	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T4W7, O95441, O96030, Q6P6A3	Gene names	ARTN, EVN
Domain Architecture	No domain graphic available
Description	Artemin precursor (Enovin) (Neublastin).

NRTN_HUMAN
NC score	0.842553 (rank : 5)	θ value	2.13179e-17 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q99748	Gene names	NRTN
Domain Architecture
Description	Neurturin precursor.

ARTN_MOUSE
NC score	0.841332 (rank : 6)	θ value	8.65492e-19 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0L2, Q3SXF4, Q3SXF5	Gene names	Artn
Domain Architecture	No domain graphic available
Description	Artemin precursor.

GDNF_MOUSE
NC score	0.715722 (rank : 7)	θ value	7.84624e-12 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P48540, O09058, P70446, P97919, P97920	Gene names	Gdnf
Domain Architecture
Description	Glial cell line-derived neurotrophic factor precursor.

GDNF_HUMAN
NC score	0.714769 (rank : 8)	θ value	2.28291e-11 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P39905, Q96L44, Q9UD33, Q9UP97	Gene names	GDNF
Domain Architecture
Description	Glial cell line-derived neurotrophic factor precursor (Astrocyte- derived trophic factor 1) (ATF-1).

MIS_HUMAN
NC score	0.110577 (rank : 9)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	17	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	P03971, O75246	Gene names	AMH, MIF
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

MIS_MOUSE
NC score	0.100332 (rank : 10)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	17	Target Neighborhood Hits	86	Shared Neighborhood Hits	12
SwissProt Accessions	P27106	Gene names	Amh
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

GDF11_HUMAN
NC score	0.096908 (rank : 11)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	73	Shared Neighborhood Hits	10
SwissProt Accessions	O95390, Q9UID1, Q9UID2	Gene names	GDF11, BMP11
Domain Architecture
Description	Growth/differentiation factor 11 precursor (GDF-11) (Bone morphogenetic protein 11).

GDF11_MOUSE
NC score	0.096812 (rank : 12)	θ value	0.125558 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	73	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1W4, Q9QX55, Q9R221	Gene names	Gdf11, Bmp11
Domain Architecture
Description	Growth/differentiation factor 11 precursor (GDF-11) (Bone morphogenetic protein 11).

GDF15_MOUSE
NC score	0.091400 (rank : 13)	θ value	0.0736092 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	71	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0J7	Gene names	Gdf15, Sbf
Domain Architecture
Description	Growth/differentiation factor 15 precursor (GDF-15).

GDF8_MOUSE
NC score	0.091271 (rank : 14)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	O08689	Gene names	Gdf8, Mstn
Domain Architecture
Description	Growth/differentiation factor 8 precursor (GDF-8) (Myostatin).

GDF8_HUMAN
NC score	0.091253 (rank : 15)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	O14793, Q6B0H2	Gene names	GDF8, MSTN
Domain Architecture
Description	Growth/differentiation factor 8 precursor (GDF-8) (Myostatin).

RTBDN_HUMAN
NC score	0.075204 (rank : 16)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BSG5, Q9BWT5	Gene names	RTBDN
Domain Architecture	No domain graphic available
Description	Retbindin precursor.

INHBB_HUMAN
NC score	0.069351 (rank : 17)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	P09529, Q8N1D3	Gene names	INHBB
Domain Architecture
Description	Inhibin beta B chain precursor (Activin beta-B chain).

GDF15_HUMAN
NC score	0.068602 (rank : 18)	θ value	θ > 10 (rank : 18)
Query Neighborhood Hits	17	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	Q99988, O14629, P78360, Q9NRT0	Gene names	GDF15, MIC1, PDF, PLAB, PTGFB
Domain Architecture
Description	Growth/differentiation factor 15 precursor (GDF-15) (Placental bone morphogenetic protein) (Placental TGF-beta) (Macrophage inhibitory cytokine 1) (MIC-1) (Prostate differentiation factor) (NSAID-regulated protein 1) (NRG-1).

INHBC_HUMAN
NC score	0.052858 (rank : 19)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	P55103	Gene names	INHBC
Domain Architecture
Description	Inhibin beta C chain precursor (Activin beta-C chain).

GDF9_MOUSE
NC score	0.038245 (rank : 20)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q07105	Gene names	Gdf9, Gdf-9
Domain Architecture
Description	Growth/differentiation factor 9 precursor (GDF-9).