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Network neighborhood for query Sequence : GDNF_HUMAN

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GDNF_HUMAN
SwissProt Accessions	P39905, Q96L44, Q9UD33, Q9UP97	Gene names	GDNF
Domain Architecture
Description	Glial cell line-derived neurotrophic factor precursor (Astrocyte- derived trophic factor 1) (ATF-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GDNF_MOUSE
θ value	1.26366e-94 (rank : 1)	NC score	0.998219 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	P48540, O09058, P70446, P97919, P97920	Gene names	Gdnf
Domain Architecture
Description	Glial cell line-derived neurotrophic factor precursor.

GDNF_HUMAN
θ value	7.66637e-92 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P39905, Q96L44, Q9UD33, Q9UP97	Gene names	GDNF
Domain Architecture
Description	Glial cell line-derived neurotrophic factor precursor (Astrocyte- derived trophic factor 1) (ATF-1).

NRTN_HUMAN
θ value	1.29331e-14 (rank : 3)	NC score	0.777765 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q99748	Gene names	NRTN
Domain Architecture
Description	Neurturin precursor.

NRTN_MOUSE
θ value	1.29331e-14 (rank : 4)	NC score	0.782768 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P97463	Gene names	Nrtn
Domain Architecture
Description	Neurturin precursor.

PSPN_HUMAN
θ value	2.28291e-11 (rank : 5)	NC score	0.714769 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	O60542	Gene names	PSPN
Domain Architecture
Description	Persephin precursor (PSP).

PSPN_MOUSE
θ value	6.21693e-09 (rank : 6)	NC score	0.677850 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	O70300	Gene names	Pspn
Domain Architecture
Description	Persephin precursor (PSP).

ARTN_MOUSE
θ value	2.61198e-07 (rank : 7)	NC score	0.623295 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0L2, Q3SXF4, Q3SXF5	Gene names	Artn
Domain Architecture	No domain graphic available
Description	Artemin precursor.

ARTN_HUMAN
θ value	4.45536e-07 (rank : 8)	NC score	0.624666 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	42	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T4W7, O95441, O96030, Q6P6A3	Gene names	ARTN, EVN
Domain Architecture	No domain graphic available
Description	Artemin precursor (Enovin) (Neublastin).

GDF5_MOUSE
θ value	0.47712 (rank : 9)	NC score	0.049874 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	P43027	Gene names	Gdf5, Bp, Gdf-5
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5).

GDF2_HUMAN
θ value	0.62314 (rank : 10)	NC score	0.057006 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UK05, Q9Y571	Gene names	GDF2, BMP9
Domain Architecture
Description	Growth/differentiation factor 2 precursor (GDF-2) (Bone morphogenetic protein 9) (BMP-9).

GDF2_MOUSE
θ value	1.38821 (rank : 11)	NC score	0.047452 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WV56, Q9QZE0	Gene names	Gdf2, Bmp9
Domain Architecture
Description	Growth/differentiation factor 2 precursor (GDF-2) (Bone morphogenetic protein 9) (BMP-9).

GDF5_HUMAN
θ value	2.36792 (rank : 12)	NC score	0.046163 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	103	Shared Neighborhood Hits	6
SwissProt Accessions	P43026, Q96SB1	Gene names	GDF5, CDMP1
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Radotermin).

SCG2_MOUSE
θ value	4.03905 (rank : 13)	NC score	0.026623 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q03517, Q80Y79, Q9CW80	Gene names	Scg2, Chgc, Scg-2
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

T240L_MOUSE
θ value	6.88961 (rank : 14)	NC score	0.015158 (rank : 16)
Query Neighborhood Hits	14	Target Neighborhood Hits	143	Shared Neighborhood Hits	2
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

MIS_HUMAN
θ value	θ > 10 (rank : 15)	NC score	0.065291 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	P03971, O75246	Gene names	AMH, MIF
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

MIS_MOUSE
θ value	θ > 10 (rank : 16)	NC score	0.051098 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	P27106	Gene names	Amh
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

Hits sorted by NC score

GDNF_HUMAN
NC score	0.999962 (rank : 1)	θ value	7.66637e-92 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P39905, Q96L44, Q9UD33, Q9UP97	Gene names	GDNF
Domain Architecture
Description	Glial cell line-derived neurotrophic factor precursor (Astrocyte- derived trophic factor 1) (ATF-1).

GDNF_MOUSE
NC score	0.998219 (rank : 2)	θ value	1.26366e-94 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	P48540, O09058, P70446, P97919, P97920	Gene names	Gdnf
Domain Architecture
Description	Glial cell line-derived neurotrophic factor precursor.

NRTN_MOUSE
NC score	0.782768 (rank : 3)	θ value	1.29331e-14 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P97463	Gene names	Nrtn
Domain Architecture
Description	Neurturin precursor.

NRTN_HUMAN
NC score	0.777765 (rank : 4)	θ value	1.29331e-14 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q99748	Gene names	NRTN
Domain Architecture
Description	Neurturin precursor.

PSPN_HUMAN
NC score	0.714769 (rank : 5)	θ value	2.28291e-11 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	O60542	Gene names	PSPN
Domain Architecture
Description	Persephin precursor (PSP).

PSPN_MOUSE
NC score	0.677850 (rank : 6)	θ value	6.21693e-09 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	O70300	Gene names	Pspn
Domain Architecture
Description	Persephin precursor (PSP).

ARTN_HUMAN
NC score	0.624666 (rank : 7)	θ value	4.45536e-07 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	42	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T4W7, O95441, O96030, Q6P6A3	Gene names	ARTN, EVN
Domain Architecture	No domain graphic available
Description	Artemin precursor (Enovin) (Neublastin).

ARTN_MOUSE
NC score	0.623295 (rank : 8)	θ value	2.61198e-07 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0L2, Q3SXF4, Q3SXF5	Gene names	Artn
Domain Architecture	No domain graphic available
Description	Artemin precursor.

MIS_HUMAN
NC score	0.065291 (rank : 9)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	14	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	P03971, O75246	Gene names	AMH, MIF
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

GDF2_HUMAN
NC score	0.057006 (rank : 10)	θ value	0.62314 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UK05, Q9Y571	Gene names	GDF2, BMP9
Domain Architecture
Description	Growth/differentiation factor 2 precursor (GDF-2) (Bone morphogenetic protein 9) (BMP-9).

MIS_MOUSE
NC score	0.051098 (rank : 11)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	14	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	P27106	Gene names	Amh
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

GDF5_MOUSE
NC score	0.049874 (rank : 12)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	P43027	Gene names	Gdf5, Bp, Gdf-5
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5).

GDF2_MOUSE
NC score	0.047452 (rank : 13)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WV56, Q9QZE0	Gene names	Gdf2, Bmp9
Domain Architecture
Description	Growth/differentiation factor 2 precursor (GDF-2) (Bone morphogenetic protein 9) (BMP-9).

GDF5_HUMAN
NC score	0.046163 (rank : 14)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	103	Shared Neighborhood Hits	6
SwissProt Accessions	P43026, Q96SB1	Gene names	GDF5, CDMP1
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Radotermin).

SCG2_MOUSE
NC score	0.026623 (rank : 15)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q03517, Q80Y79, Q9CW80	Gene names	Scg2, Chgc, Scg-2
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

T240L_MOUSE
NC score	0.015158 (rank : 16)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	143	Shared Neighborhood Hits	2
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).