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Network neighborhood for query Sequence : MCM8_HUMAN

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MCM8_HUMAN
SwissProt Accessions	Q9UJA3, Q495R4, Q495R7, Q86US4, Q969I5	Gene names	MCM8, C20orf154
Domain Architecture
Description	DNA replication licensing factor MCM8 (Minichromosome maintenance 8).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MCM8_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UJA3, Q495R4, Q495R7, Q86US4, Q969I5	Gene names	MCM8, C20orf154
Domain Architecture
Description	DNA replication licensing factor MCM8 (Minichromosome maintenance 8).

MCM8_MOUSE
θ value	0 (rank : 2)	NC score	0.998559 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	Q9CWV1, Q80US2, Q80VI0	Gene names	Mcm8
Domain Architecture	No domain graphic available
Description	DNA replication licensing factor MCM8 (Minichromosome maintenance 8).

MCM2_HUMAN
θ value	2.47191e-82 (rank : 3)	NC score	0.942222 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	P49736, Q14577, Q15023, Q8N2V1, Q969W7, Q96AE1, Q9BRM7	Gene names	MCM2, BM28, CDCL1, KIAA0030
Domain Architecture
Description	DNA replication licensing factor MCM2 (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28).

MCM2_MOUSE
θ value	5.50685e-82 (rank : 4)	NC score	0.941730 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	33	Shared Neighborhood Hits	14
SwissProt Accessions	P97310, O08971, O89057, Q8C2R0	Gene names	Mcm2, Bm28, Cdcl1, Kiaa0030, Mcmd2
Domain Architecture
Description	DNA replication licensing factor MCM2 (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28).

MCM4_MOUSE
θ value	1.8332e-77 (rank : 5)	NC score	0.935045 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	53	Shared Neighborhood Hits	15
SwissProt Accessions	P49717, O89056	Gene names	Mcm4, Cdc21, Mcmd4
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

MCM4_HUMAN
θ value	8.81223e-72 (rank : 6)	NC score	0.932277 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	59	Shared Neighborhood Hits	15
SwissProt Accessions	P33991, Q8NEH1, Q99658	Gene names	MCM4, CDC21
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

MCM6_MOUSE
θ value	2.65329e-68 (rank : 7)	NC score	0.929903 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	P97311, Q80YQ7	Gene names	Mcm6, Mcmd6, Mis5
Domain Architecture
Description	DNA replication licensing factor MCM6 (Mis5 homolog).

MCM6_HUMAN
θ value	5.91091e-68 (rank : 8)	NC score	0.929618 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	Q14566, Q13504, Q99859	Gene names	MCM6
Domain Architecture
Description	DNA replication licensing factor MCM6 (p105MCM).

MCM7_MOUSE
θ value	5.91091e-68 (rank : 9)	NC score	0.933696 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	Q61881	Gene names	Mcm7, Cdc47, Mcmd7
Domain Architecture
Description	DNA replication licensing factor MCM7 (CDC47 homolog).

MCM7_HUMAN
θ value	8.53533e-67 (rank : 10)	NC score	0.933532 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	P33993, Q15076, Q96D34, Q96GL1	Gene names	MCM7, CDC47, MCM2
Domain Architecture
Description	DNA replication licensing factor MCM7 (CDC47 homolog) (P1.1-MCM3).

MCM5_HUMAN
θ value	1.04338e-64 (rank : 11)	NC score	0.928560 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	37	Shared Neighborhood Hits	15
SwissProt Accessions	P33992, O60785, Q14578, Q9BTJ4, Q9BWL8	Gene names	MCM5, CDC46
Domain Architecture
Description	DNA replication licensing factor MCM5 (CDC46 homolog) (P1-CDC46).

MCM5_MOUSE
θ value	3.03575e-64 (rank : 12)	NC score	0.927508 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	P49718	Gene names	Mcm5, Cdc46, Mcmd5
Domain Architecture
Description	DNA replication licensing factor MCM5 (CDC46 homolog) (P1-CDC46).

MCM3_HUMAN
θ value	2.94036e-59 (rank : 13)	NC score	0.916385 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	87	Shared Neighborhood Hits	14
SwissProt Accessions	P25205, Q92660, Q9BTR3, Q9NUE7	Gene names	MCM3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF subunit beta) (P102 protein) (P1-MCM3).

MCM3_MOUSE
θ value	1.36585e-56 (rank : 14)	NC score	0.912108 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	P25206, Q61492	Gene names	Mcm3, Mcmd, Mcmd3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3).

PLCD1_HUMAN
θ value	0.279714 (rank : 15)	NC score	0.031181 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PLCD1_MOUSE
θ value	1.38821 (rank : 16)	NC score	0.022701 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

DYH9_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.020653 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	291	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

OPA1_HUMAN
θ value	2.36792 (rank : 18)	NC score	0.026756 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

OPA1_MOUSE
θ value	2.36792 (rank : 19)	NC score	0.026859 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	P58281, Q3ULA5, Q8BKU7, Q8BLL3, Q8BM08, Q8R3J7	Gene names	Opa1
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1 homolog) (Large GTP-binding protein) (LargeG) [Contains: Dynamin-like 120 kDa protein, form S1].

TRPM2_MOUSE
θ value	2.36792 (rank : 20)	NC score	0.014578 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

CLPX_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.025554 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_MOUSE
θ value	3.0926 (rank : 22)	NC score	0.025588 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

DJC12_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.012236 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	141	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKB3, Q9UKB2	Gene names	DNAJC12, JDP1
Domain Architecture
Description	DnaJ homolog subfamily C member 12 (J domain-containing protein 1).

PEG3_MOUSE
θ value	4.03905 (rank : 24)	NC score	-0.000725 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	1101	Shared Neighborhood Hits	2
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

CN045_HUMAN
θ value	8.99809 (rank : 25)	NC score	0.018847 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	227	Shared Neighborhood Hits	3
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

Hits sorted by NC score

MCM8_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UJA3, Q495R4, Q495R7, Q86US4, Q969I5	Gene names	MCM8, C20orf154
Domain Architecture
Description	DNA replication licensing factor MCM8 (Minichromosome maintenance 8).

MCM8_MOUSE
NC score	0.998559 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	Q9CWV1, Q80US2, Q80VI0	Gene names	Mcm8
Domain Architecture	No domain graphic available
Description	DNA replication licensing factor MCM8 (Minichromosome maintenance 8).

MCM2_HUMAN
NC score	0.942222 (rank : 3)	θ value	2.47191e-82 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	P49736, Q14577, Q15023, Q8N2V1, Q969W7, Q96AE1, Q9BRM7	Gene names	MCM2, BM28, CDCL1, KIAA0030
Domain Architecture
Description	DNA replication licensing factor MCM2 (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28).

MCM2_MOUSE
NC score	0.941730 (rank : 4)	θ value	5.50685e-82 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	33	Shared Neighborhood Hits	14
SwissProt Accessions	P97310, O08971, O89057, Q8C2R0	Gene names	Mcm2, Bm28, Cdcl1, Kiaa0030, Mcmd2
Domain Architecture
Description	DNA replication licensing factor MCM2 (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28).

MCM4_MOUSE
NC score	0.935045 (rank : 5)	θ value	1.8332e-77 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	53	Shared Neighborhood Hits	15
SwissProt Accessions	P49717, O89056	Gene names	Mcm4, Cdc21, Mcmd4
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

MCM7_MOUSE
NC score	0.933696 (rank : 6)	θ value	5.91091e-68 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	Q61881	Gene names	Mcm7, Cdc47, Mcmd7
Domain Architecture
Description	DNA replication licensing factor MCM7 (CDC47 homolog).

MCM7_HUMAN
NC score	0.933532 (rank : 7)	θ value	8.53533e-67 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	P33993, Q15076, Q96D34, Q96GL1	Gene names	MCM7, CDC47, MCM2
Domain Architecture
Description	DNA replication licensing factor MCM7 (CDC47 homolog) (P1.1-MCM3).

MCM4_HUMAN
NC score	0.932277 (rank : 8)	θ value	8.81223e-72 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	59	Shared Neighborhood Hits	15
SwissProt Accessions	P33991, Q8NEH1, Q99658	Gene names	MCM4, CDC21
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

MCM6_MOUSE
NC score	0.929903 (rank : 9)	θ value	2.65329e-68 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	P97311, Q80YQ7	Gene names	Mcm6, Mcmd6, Mis5
Domain Architecture
Description	DNA replication licensing factor MCM6 (Mis5 homolog).

MCM6_HUMAN
NC score	0.929618 (rank : 10)	θ value	5.91091e-68 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	Q14566, Q13504, Q99859	Gene names	MCM6
Domain Architecture
Description	DNA replication licensing factor MCM6 (p105MCM).

MCM5_HUMAN
NC score	0.928560 (rank : 11)	θ value	1.04338e-64 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	37	Shared Neighborhood Hits	15
SwissProt Accessions	P33992, O60785, Q14578, Q9BTJ4, Q9BWL8	Gene names	MCM5, CDC46
Domain Architecture
Description	DNA replication licensing factor MCM5 (CDC46 homolog) (P1-CDC46).

MCM5_MOUSE
NC score	0.927508 (rank : 12)	θ value	3.03575e-64 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	36	Shared Neighborhood Hits	14
SwissProt Accessions	P49718	Gene names	Mcm5, Cdc46, Mcmd5
Domain Architecture
Description	DNA replication licensing factor MCM5 (CDC46 homolog) (P1-CDC46).

MCM3_HUMAN
NC score	0.916385 (rank : 13)	θ value	2.94036e-59 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	87	Shared Neighborhood Hits	14
SwissProt Accessions	P25205, Q92660, Q9BTR3, Q9NUE7	Gene names	MCM3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF subunit beta) (P102 protein) (P1-MCM3).

MCM3_MOUSE
NC score	0.912108 (rank : 14)	θ value	1.36585e-56 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	P25206, Q61492	Gene names	Mcm3, Mcmd, Mcmd3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3).

PLCD1_HUMAN
NC score	0.031181 (rank : 15)	θ value	0.279714 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

OPA1_MOUSE
NC score	0.026859 (rank : 16)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	P58281, Q3ULA5, Q8BKU7, Q8BLL3, Q8BM08, Q8R3J7	Gene names	Opa1
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1 homolog) (Large GTP-binding protein) (LargeG) [Contains: Dynamin-like 120 kDa protein, form S1].

OPA1_HUMAN
NC score	0.026756 (rank : 17)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

CLPX_MOUSE
NC score	0.025588 (rank : 18)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_HUMAN
NC score	0.025554 (rank : 19)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

PLCD1_MOUSE
NC score	0.022701 (rank : 20)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

DYH9_HUMAN
NC score	0.020653 (rank : 21)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	291	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

CN045_HUMAN
NC score	0.018847 (rank : 22)	θ value	8.99809 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	227	Shared Neighborhood Hits	3
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

TRPM2_MOUSE
NC score	0.014578 (rank : 23)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

DJC12_HUMAN
NC score	0.012236 (rank : 24)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	141	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKB3, Q9UKB2	Gene names	DNAJC12, JDP1
Domain Architecture
Description	DnaJ homolog subfamily C member 12 (J domain-containing protein 1).

PEG3_MOUSE
NC score	-0.000725 (rank : 25)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	1101	Shared Neighborhood Hits	2
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).