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Network neighborhood for query Sequence : MA2B1_MOUSE

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MA2B1_MOUSE
SwissProt Accessions	O09159, O55037, Q64443, Q9DBQ1	Gene names	Man2b1, Laman, Man2b, Manb
Domain Architecture
Description	Lysosomal alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase, alpha B) (Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase alpha class 2B member 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MA2B1_HUMAN
θ value	0 (rank : 1)	NC score	0.996726 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	O00754, O15330, Q16680, Q93094, Q9BW13	Gene names	MAN2B1, LAMAN, MANB
Domain Architecture
Description	Lysosomal alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase, alpha B) (Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase alpha class 2B member 1) [Contains: Lysosomal alpha-mannosidase A peptide; Lysosomal alpha-mannosidase B peptide; Lysosomal alpha-mannosidase C peptide; Lysosomal alpha-mannosidase D peptide; Lysosomal alpha- mannosidase E peptide].

MA2B1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	O09159, O55037, Q64443, Q9DBQ1	Gene names	Man2b1, Laman, Man2b, Manb
Domain Architecture
Description	Lysosomal alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase, alpha B) (Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase alpha class 2B member 1).

MA2B2_HUMAN
θ value	1.77149e-80 (rank : 3)	NC score	0.893901 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2E5, Q66MP2, Q86T67	Gene names	MAN2B2, KIAA0935
Domain Architecture
Description	Epididymis-specific alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase alpha class 2B member 2).

MA2B2_MOUSE
θ value	1.65806e-78 (rank : 4)	NC score	0.891510 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	O54782, Q69ZV1, Q8BH85, Q9DBK2	Gene names	Man2b2, Kiaa0935
Domain Architecture
Description	Epididymis-specific alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase alpha class 2B member 2).

MA2A1_HUMAN
θ value	2.39424e-77 (rank : 5)	NC score	0.873372 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q16706, Q16767	Gene names	MAN2A1, MANA2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1).

MA2A1_MOUSE
θ value	2.24094e-75 (rank : 6)	NC score	0.870125 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	P27046	Gene names	Man2a1, Mana2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1) (AMAN II).

MA2A2_HUMAN
θ value	3.96481e-64 (rank : 7)	NC score	0.865854 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	P49641, Q13754	Gene names	MAN2A2, MANA2X
Domain Architecture
Description	Alpha-mannosidase IIx (EC 3.2.1.114) (Mannosyl-oligosaccharide 1,3- 1,6-alpha-mannosidase) (MAN IIx) (Mannosidase alpha class 2A member 2).

MA2C1_MOUSE
θ value	0.000786445 (rank : 8)	NC score	0.252436 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q91W89	Gene names	Man2c1
Domain Architecture
Description	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1).

MA2C1_HUMAN
θ value	0.125558 (rank : 9)	NC score	0.199083 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NTJ4, Q13358, Q9UL64	Gene names	MAN2C1
Domain Architecture
Description	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1) (Alpha mannosidase 6A8B).

KCD13_MOUSE
θ value	0.47712 (rank : 10)	NC score	0.052355 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGV7, Q6AXE9	Gene names	Kctd13, Poldip1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD13 (Polymerase delta-interacting protein 1).

KCD10_MOUSE
θ value	0.813845 (rank : 11)	NC score	0.050986 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q922M3	Gene names	Kctd10
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD10.

KCD13_HUMAN
θ value	0.813845 (rank : 12)	NC score	0.050466 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ19, Q96P93, Q96SA1	Gene names	KCTD13, PDIP1, POLDIP1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD13 (Polymerase delta-interacting protein 1) (TNFAIP1-like protein).

KCD10_HUMAN
θ value	1.38821 (rank : 13)	NC score	0.045689 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H3F6, Q53HN2, Q59FV1, Q6PL47, Q96SU0	Gene names	KCTD10, ULR061
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD10.

LRC29_HUMAN
θ value	3.0926 (rank : 14)	NC score	0.021107 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

PERT_HUMAN
θ value	3.0926 (rank : 15)	NC score	0.010044 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	221	Shared Neighborhood Hits	2
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

MAFB_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.013156 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5Q3, Q9H1F1	Gene names	MAFB, KRML
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B).

MAFB_MOUSE
θ value	6.88961 (rank : 17)	NC score	0.013164 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	P54841	Gene names	Mafb, Krml, Maf1
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) (Transcription factor MAF1) (Segmentation protein KR) (Kreisler).

Hits sorted by NC score

MA2B1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	O09159, O55037, Q64443, Q9DBQ1	Gene names	Man2b1, Laman, Man2b, Manb
Domain Architecture
Description	Lysosomal alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase, alpha B) (Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase alpha class 2B member 1).

MA2B1_HUMAN
NC score	0.996726 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	O00754, O15330, Q16680, Q93094, Q9BW13	Gene names	MAN2B1, LAMAN, MANB
Domain Architecture
Description	Lysosomal alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase, alpha B) (Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase alpha class 2B member 1) [Contains: Lysosomal alpha-mannosidase A peptide; Lysosomal alpha-mannosidase B peptide; Lysosomal alpha-mannosidase C peptide; Lysosomal alpha-mannosidase D peptide; Lysosomal alpha- mannosidase E peptide].

MA2B2_HUMAN
NC score	0.893901 (rank : 3)	θ value	1.77149e-80 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2E5, Q66MP2, Q86T67	Gene names	MAN2B2, KIAA0935
Domain Architecture
Description	Epididymis-specific alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase alpha class 2B member 2).

MA2B2_MOUSE
NC score	0.891510 (rank : 4)	θ value	1.65806e-78 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	O54782, Q69ZV1, Q8BH85, Q9DBK2	Gene names	Man2b2, Kiaa0935
Domain Architecture
Description	Epididymis-specific alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase alpha class 2B member 2).

MA2A1_HUMAN
NC score	0.873372 (rank : 5)	θ value	2.39424e-77 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q16706, Q16767	Gene names	MAN2A1, MANA2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1).

MA2A1_MOUSE
NC score	0.870125 (rank : 6)	θ value	2.24094e-75 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	P27046	Gene names	Man2a1, Mana2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1) (AMAN II).

MA2A2_HUMAN
NC score	0.865854 (rank : 7)	θ value	3.96481e-64 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	P49641, Q13754	Gene names	MAN2A2, MANA2X
Domain Architecture
Description	Alpha-mannosidase IIx (EC 3.2.1.114) (Mannosyl-oligosaccharide 1,3- 1,6-alpha-mannosidase) (MAN IIx) (Mannosidase alpha class 2A member 2).

MA2C1_MOUSE
NC score	0.252436 (rank : 8)	θ value	0.000786445 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q91W89	Gene names	Man2c1
Domain Architecture
Description	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1).

MA2C1_HUMAN
NC score	0.199083 (rank : 9)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NTJ4, Q13358, Q9UL64	Gene names	MAN2C1
Domain Architecture
Description	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1) (Alpha mannosidase 6A8B).

KCD13_MOUSE
NC score	0.052355 (rank : 10)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGV7, Q6AXE9	Gene names	Kctd13, Poldip1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD13 (Polymerase delta-interacting protein 1).

KCD10_MOUSE
NC score	0.050986 (rank : 11)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q922M3	Gene names	Kctd10
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD10.

KCD13_HUMAN
NC score	0.050466 (rank : 12)	θ value	0.813845 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ19, Q96P93, Q96SA1	Gene names	KCTD13, PDIP1, POLDIP1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD13 (Polymerase delta-interacting protein 1) (TNFAIP1-like protein).

KCD10_HUMAN
NC score	0.045689 (rank : 13)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H3F6, Q53HN2, Q59FV1, Q6PL47, Q96SU0	Gene names	KCTD10, ULR061
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD10.

LRC29_HUMAN
NC score	0.021107 (rank : 14)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

MAFB_MOUSE
NC score	0.013164 (rank : 15)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	P54841	Gene names	Mafb, Krml, Maf1
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) (Transcription factor MAF1) (Segmentation protein KR) (Kreisler).

MAFB_HUMAN
NC score	0.013156 (rank : 16)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5Q3, Q9H1F1	Gene names	MAFB, KRML
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B).

PERT_HUMAN
NC score	0.010044 (rank : 17)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	221	Shared Neighborhood Hits	2
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).