Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : MA2A2_HUMAN

For an explanation of this page, click here

MA2A2_HUMAN
SwissProt Accessions	P49641, Q13754	Gene names	MAN2A2, MANA2X
Domain Architecture
Description	Alpha-mannosidase IIx (EC 3.2.1.114) (Mannosyl-oligosaccharide 1,3- 1,6-alpha-mannosidase) (MAN IIx) (Mannosidase alpha class 2A member 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MA2A1_HUMAN
θ value	0 (rank : 1)	NC score	0.989476 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q16706, Q16767	Gene names	MAN2A1, MANA2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1).

MA2A1_MOUSE
θ value	0 (rank : 2)	NC score	0.989843 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	P27046	Gene names	Man2a1, Mana2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1) (AMAN II).

MA2A2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P49641, Q13754	Gene names	MAN2A2, MANA2X
Domain Architecture
Description	Alpha-mannosidase IIx (EC 3.2.1.114) (Mannosyl-oligosaccharide 1,3- 1,6-alpha-mannosidase) (MAN IIx) (Mannosidase alpha class 2A member 2).

MA2B1_MOUSE
θ value	3.96481e-64 (rank : 4)	NC score	0.865854 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	O09159, O55037, Q64443, Q9DBQ1	Gene names	Man2b1, Laman, Man2b, Manb
Domain Architecture
Description	Lysosomal alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase, alpha B) (Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase alpha class 2B member 1).

MA2B1_HUMAN
θ value	8.83269e-64 (rank : 5)	NC score	0.863192 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O00754, O15330, Q16680, Q93094, Q9BW13	Gene names	MAN2B1, LAMAN, MANB
Domain Architecture
Description	Lysosomal alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase, alpha B) (Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase alpha class 2B member 1) [Contains: Lysosomal alpha-mannosidase A peptide; Lysosomal alpha-mannosidase B peptide; Lysosomal alpha-mannosidase C peptide; Lysosomal alpha-mannosidase D peptide; Lysosomal alpha- mannosidase E peptide].

MA2B2_HUMAN
θ value	7.47731e-63 (rank : 6)	NC score	0.861493 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2E5, Q66MP2, Q86T67	Gene names	MAN2B2, KIAA0935
Domain Architecture
Description	Epididymis-specific alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase alpha class 2B member 2).

MA2B2_MOUSE
θ value	3.974e-56 (rank : 7)	NC score	0.857121 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	O54782, Q69ZV1, Q8BH85, Q9DBK2	Gene names	Man2b2, Kiaa0935
Domain Architecture
Description	Epididymis-specific alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase alpha class 2B member 2).

MA2C1_MOUSE
θ value	0.000121331 (rank : 8)	NC score	0.291008 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q91W89	Gene names	Man2c1
Domain Architecture
Description	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1).

MA2C1_HUMAN
θ value	0.000158464 (rank : 9)	NC score	0.254354 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NTJ4, Q13358, Q9UL64	Gene names	MAN2C1
Domain Architecture
Description	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1) (Alpha mannosidase 6A8B).

AP3D1_MOUSE
θ value	0.47712 (rank : 10)	NC score	0.022887 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	144	Shared Neighborhood Hits	2
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

KCC4_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.000669 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	841	Shared Neighborhood Hits	3
SwissProt Accessions	Q16566	Gene names	CAMK4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).

MFAP3_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.010880 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	Q922T2, Q8BHK5	Gene names	Mfap3
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 3 precursor.

PGCA_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.002050 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	821	Shared Neighborhood Hits	2
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

Hits sorted by NC score

MA2A2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P49641, Q13754	Gene names	MAN2A2, MANA2X
Domain Architecture
Description	Alpha-mannosidase IIx (EC 3.2.1.114) (Mannosyl-oligosaccharide 1,3- 1,6-alpha-mannosidase) (MAN IIx) (Mannosidase alpha class 2A member 2).

MA2A1_MOUSE
NC score	0.989843 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	P27046	Gene names	Man2a1, Mana2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1) (AMAN II).

MA2A1_HUMAN
NC score	0.989476 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q16706, Q16767	Gene names	MAN2A1, MANA2
Domain Architecture
Description	Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase) (MAN II) (Golgi alpha- mannosidase II) (Mannosidase alpha class 2A member 1).

MA2B1_MOUSE
NC score	0.865854 (rank : 4)	θ value	3.96481e-64 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	O09159, O55037, Q64443, Q9DBQ1	Gene names	Man2b1, Laman, Man2b, Manb
Domain Architecture
Description	Lysosomal alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase, alpha B) (Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase alpha class 2B member 1).

MA2B1_HUMAN
NC score	0.863192 (rank : 5)	θ value	8.83269e-64 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	O00754, O15330, Q16680, Q93094, Q9BW13	Gene names	MAN2B1, LAMAN, MANB
Domain Architecture
Description	Lysosomal alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase, alpha B) (Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase alpha class 2B member 1) [Contains: Lysosomal alpha-mannosidase A peptide; Lysosomal alpha-mannosidase B peptide; Lysosomal alpha-mannosidase C peptide; Lysosomal alpha-mannosidase D peptide; Lysosomal alpha- mannosidase E peptide].

MA2B2_HUMAN
NC score	0.861493 (rank : 6)	θ value	7.47731e-63 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2E5, Q66MP2, Q86T67	Gene names	MAN2B2, KIAA0935
Domain Architecture
Description	Epididymis-specific alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase alpha class 2B member 2).

MA2B2_MOUSE
NC score	0.857121 (rank : 7)	θ value	3.974e-56 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	O54782, Q69ZV1, Q8BH85, Q9DBK2	Gene names	Man2b2, Kiaa0935
Domain Architecture
Description	Epididymis-specific alpha-mannosidase precursor (EC 3.2.1.24) (Mannosidase alpha class 2B member 2).

MA2C1_MOUSE
NC score	0.291008 (rank : 8)	θ value	0.000121331 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q91W89	Gene names	Man2c1
Domain Architecture
Description	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1).

MA2C1_HUMAN
NC score	0.254354 (rank : 9)	θ value	0.000158464 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NTJ4, Q13358, Q9UL64	Gene names	MAN2C1
Domain Architecture
Description	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1) (Alpha mannosidase 6A8B).

AP3D1_MOUSE
NC score	0.022887 (rank : 10)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	144	Shared Neighborhood Hits	2
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

MFAP3_MOUSE
NC score	0.010880 (rank : 11)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	Q922T2, Q8BHK5	Gene names	Mfap3
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 3 precursor.

PGCA_HUMAN
NC score	0.002050 (rank : 12)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	821	Shared Neighborhood Hits	2
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

KCC4_HUMAN
NC score	0.000669 (rank : 13)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	841	Shared Neighborhood Hits	3
SwissProt Accessions	Q16566	Gene names	CAMK4
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type IV (EC 2.7.11.17) (CAM kinase-GR) (CaMK IV).