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Network neighborhood for query Sequence : LX12B_MOUSE

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LX12B_MOUSE
SwissProt Accessions	O70582	Gene names	Alox12b, Aloxe2
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX) (Epidermis-type lipoxygenase 2) (e-LOX 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LOXE3_HUMAN
θ value	0 (rank : 1)	NC score	0.994355 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BYJ1, Q9H4F2, Q9HC22	Gene names	ALOXE3
Domain Architecture
Description	Epidermis-type lipoxygenase 3 (EC 1.13.11.-) (e-LOX-3).

LOXE3_MOUSE
θ value	0 (rank : 2)	NC score	0.994438 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WV07	Gene names	Aloxe3
Domain Architecture
Description	Epidermis-type lipoxygenase 3 (EC 1.13.11.-) (e-LOX-3).

LX12B_HUMAN
θ value	0 (rank : 3)	NC score	0.999522 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	26	Shared Neighborhood Hits	19
SwissProt Accessions	O75342	Gene names	ALOX12B
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX).

LX12B_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	O70582	Gene names	Alox12b, Aloxe2
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX) (Epidermis-type lipoxygenase 2) (e-LOX 2).

LX15B_HUMAN
θ value	0 (rank : 5)	NC score	0.992225 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	O15296, Q8IYQ2, Q8TEV3, Q8TEV4, Q8TEV5, Q8TEV6, Q9UKM4	Gene names	ALOX15B
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (15- lipoxygenase 2).

LX15B_MOUSE
θ value	0 (rank : 6)	NC score	0.992240 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	O35936	Gene names	Alox15b, Alox8
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (8S- lipoxygenase) (8S-LOX).

LOX5_HUMAN
θ value	8.91014e-149 (rank : 7)	NC score	0.979541 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	P09917	Gene names	ALOX5, LOG5
Domain Architecture
Description	Arachidonate 5-lipoxygenase (EC 1.13.11.34) (5-lipoxygenase) (5-LO).

LOX5_MOUSE
θ value	8.91014e-149 (rank : 8)	NC score	0.980636 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	P48999	Gene names	Alox5
Domain Architecture
Description	Arachidonate 5-lipoxygenase (EC 1.13.11.34) (5-lipoxygenase) (5-LO).

LOX12_HUMAN
θ value	9.89713e-132 (rank : 9)	NC score	0.972960 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	P18054, O95569, Q6ISF8, Q9UQM4	Gene names	ALOX12, LOG12
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

LOX12_MOUSE
θ value	6.21357e-126 (rank : 10)	NC score	0.971885 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	P39655, Q8BHG4	Gene names	Alox12, Alox12p
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

LX12L_MOUSE
θ value	8.41738e-115 (rank : 11)	NC score	0.970407 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	15	Shared Neighborhood Hits	14
SwissProt Accessions	P39654, Q4FJY9, Q5F2E3, Q6PHB2	Gene names	Alox12l, Alox15
Domain Architecture
Description	Arachidonate 12-lipoxygenase, leukocyte-type (EC 1.13.11.31) (12-LOX).

LOX15_HUMAN
θ value	1.43579e-114 (rank : 12)	NC score	0.968746 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	P16050, Q8N6R7, Q99657	Gene names	ALOX15, LOG15
Domain Architecture
Description	Arachidonate 15-lipoxygenase (EC 1.13.11.33) (Arachidonate omega-6 lipoxygenase) (15-LOX).

LX12E_MOUSE
θ value	1.25781e-110 (rank : 13)	NC score	0.967635 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	P55249, Q91YW6	Gene names	Alox12e, Alox12-ps2, Aloxe
Domain Architecture
Description	Arachidonate 12-lipoxygenase, epidermal-type (EC 1.13.11.31) (12-LOX).

PKDRE_MOUSE
θ value	0.00134147 (rank : 14)	NC score	0.170147 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	76	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

P_MOUSE
θ value	0.00665767 (rank : 15)	NC score	0.062599 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q62052	Gene names	Oca2, P
Domain Architecture	No domain graphic available
Description	P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein).

PKDRE_HUMAN
θ value	1.06291 (rank : 16)	NC score	0.102062 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	64	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

LIPL_HUMAN
θ value	1.81305 (rank : 17)	NC score	0.011743 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P06858, Q16282, Q16283, Q96FC4	Gene names	LPL, LIPD
Domain Architecture
Description	Lipoprotein lipase precursor (EC 3.1.1.34) (LPL).

K0133_HUMAN
θ value	4.03905 (rank : 18)	NC score	0.034672 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q14146	Gene names	KIAA0133
Domain Architecture	No domain graphic available
Description	Protein KIAA0133.

OSBL1_MOUSE
θ value	5.27518 (rank : 19)	NC score	0.003157 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	336	Shared Neighborhood Hits	3
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

M3K15_HUMAN
θ value	6.88961 (rank : 20)	NC score	-0.002363 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	914	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).

YLPM1_MOUSE
θ value	6.88961 (rank : 21)	NC score	0.004951 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	505	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ETFD_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.006937 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q921G7, Q3U7K2, Q8BK82, Q9DCT9	Gene names	Etfdh
Domain Architecture	No domain graphic available
Description	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (EC 1.5.5.1) (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring- flavoprotein dehydrogenase).

Hits sorted by NC score

LX12B_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	O70582	Gene names	Alox12b, Aloxe2
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX) (Epidermis-type lipoxygenase 2) (e-LOX 2).

LX12B_HUMAN
NC score	0.999522 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	26	Shared Neighborhood Hits	19
SwissProt Accessions	O75342	Gene names	ALOX12B
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX).

LOXE3_MOUSE
NC score	0.994438 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	16
SwissProt Accessions	Q9WV07	Gene names	Aloxe3
Domain Architecture
Description	Epidermis-type lipoxygenase 3 (EC 1.13.11.-) (e-LOX-3).

LOXE3_HUMAN
NC score	0.994355 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BYJ1, Q9H4F2, Q9HC22	Gene names	ALOXE3
Domain Architecture
Description	Epidermis-type lipoxygenase 3 (EC 1.13.11.-) (e-LOX-3).

LX15B_MOUSE
NC score	0.992240 (rank : 5)	θ value	0 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	O35936	Gene names	Alox15b, Alox8
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (8S- lipoxygenase) (8S-LOX).

LX15B_HUMAN
NC score	0.992225 (rank : 6)	θ value	0 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	O15296, Q8IYQ2, Q8TEV3, Q8TEV4, Q8TEV5, Q8TEV6, Q9UKM4	Gene names	ALOX15B
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (15- lipoxygenase 2).

LOX5_MOUSE
NC score	0.980636 (rank : 7)	θ value	8.91014e-149 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	P48999	Gene names	Alox5
Domain Architecture
Description	Arachidonate 5-lipoxygenase (EC 1.13.11.34) (5-lipoxygenase) (5-LO).

LOX5_HUMAN
NC score	0.979541 (rank : 8)	θ value	8.91014e-149 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	P09917	Gene names	ALOX5, LOG5
Domain Architecture
Description	Arachidonate 5-lipoxygenase (EC 1.13.11.34) (5-lipoxygenase) (5-LO).

LOX12_HUMAN
NC score	0.972960 (rank : 9)	θ value	9.89713e-132 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	P18054, O95569, Q6ISF8, Q9UQM4	Gene names	ALOX12, LOG12
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

LOX12_MOUSE
NC score	0.971885 (rank : 10)	θ value	6.21357e-126 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	P39655, Q8BHG4	Gene names	Alox12, Alox12p
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

LX12L_MOUSE
NC score	0.970407 (rank : 11)	θ value	8.41738e-115 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	15	Shared Neighborhood Hits	14
SwissProt Accessions	P39654, Q4FJY9, Q5F2E3, Q6PHB2	Gene names	Alox12l, Alox15
Domain Architecture
Description	Arachidonate 12-lipoxygenase, leukocyte-type (EC 1.13.11.31) (12-LOX).

LOX15_HUMAN
NC score	0.968746 (rank : 12)	θ value	1.43579e-114 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	P16050, Q8N6R7, Q99657	Gene names	ALOX15, LOG15
Domain Architecture
Description	Arachidonate 15-lipoxygenase (EC 1.13.11.33) (Arachidonate omega-6 lipoxygenase) (15-LOX).

LX12E_MOUSE
NC score	0.967635 (rank : 13)	θ value	1.25781e-110 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	P55249, Q91YW6	Gene names	Alox12e, Alox12-ps2, Aloxe
Domain Architecture
Description	Arachidonate 12-lipoxygenase, epidermal-type (EC 1.13.11.31) (12-LOX).

PKDRE_MOUSE
NC score	0.170147 (rank : 14)	θ value	0.00134147 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	76	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PKDRE_HUMAN
NC score	0.102062 (rank : 15)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	64	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

P_MOUSE
NC score	0.062599 (rank : 16)	θ value	0.00665767 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q62052	Gene names	Oca2, P
Domain Architecture	No domain graphic available
Description	P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein).

K0133_HUMAN
NC score	0.034672 (rank : 17)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q14146	Gene names	KIAA0133
Domain Architecture	No domain graphic available
Description	Protein KIAA0133.

LIPL_HUMAN
NC score	0.011743 (rank : 18)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P06858, Q16282, Q16283, Q96FC4	Gene names	LPL, LIPD
Domain Architecture
Description	Lipoprotein lipase precursor (EC 3.1.1.34) (LPL).

ETFD_MOUSE
NC score	0.006937 (rank : 19)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q921G7, Q3U7K2, Q8BK82, Q9DCT9	Gene names	Etfdh
Domain Architecture	No domain graphic available
Description	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (EC 1.5.5.1) (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring- flavoprotein dehydrogenase).

YLPM1_MOUSE
NC score	0.004951 (rank : 20)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	505	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

OSBL1_MOUSE
NC score	0.003157 (rank : 21)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	336	Shared Neighborhood Hits	3
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

M3K15_HUMAN
NC score	-0.002363 (rank : 22)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	914	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).