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Network neighborhood for query Sequence : LOX15_HUMAN

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LOX15_HUMAN
SwissProt Accessions	P16050, Q8N6R7, Q99657	Gene names	ALOX15, LOG15
Domain Architecture
Description	Arachidonate 15-lipoxygenase (EC 1.13.11.33) (Arachidonate omega-6 lipoxygenase) (15-LOX).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LOX12_HUMAN
θ value	0 (rank : 1)	NC score	0.997115 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	P18054, O95569, Q6ISF8, Q9UQM4	Gene names	ALOX12, LOG12
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

LOX12_MOUSE
θ value	0 (rank : 2)	NC score	0.997147 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	P39655, Q8BHG4	Gene names	Alox12, Alox12p
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

LOX15_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P16050, Q8N6R7, Q99657	Gene names	ALOX15, LOG15
Domain Architecture
Description	Arachidonate 15-lipoxygenase (EC 1.13.11.33) (Arachidonate omega-6 lipoxygenase) (15-LOX).

LX12E_MOUSE
θ value	0 (rank : 4)	NC score	0.997774 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	P55249, Q91YW6	Gene names	Alox12e, Alox12-ps2, Aloxe
Domain Architecture
Description	Arachidonate 12-lipoxygenase, epidermal-type (EC 1.13.11.31) (12-LOX).

LX12L_MOUSE
θ value	0 (rank : 5)	NC score	0.999000 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	P39654, Q4FJY9, Q5F2E3, Q6PHB2	Gene names	Alox12l, Alox15
Domain Architecture
Description	Arachidonate 12-lipoxygenase, leukocyte-type (EC 1.13.11.31) (12-LOX).

LOX5_MOUSE
θ value	1.16911e-132 (rank : 6)	NC score	0.973854 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	P48999	Gene names	Alox5
Domain Architecture
Description	Arachidonate 5-lipoxygenase (EC 1.13.11.34) (5-lipoxygenase) (5-LO).

LOX5_HUMAN
θ value	2.60451e-132 (rank : 7)	NC score	0.972757 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	P09917	Gene names	ALOX5, LOG5
Domain Architecture
Description	Arachidonate 5-lipoxygenase (EC 1.13.11.34) (5-lipoxygenase) (5-LO).

LOXE3_HUMAN
θ value	6.01832e-121 (rank : 8)	NC score	0.969934 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BYJ1, Q9H4F2, Q9HC22	Gene names	ALOXE3
Domain Architecture
Description	Epidermis-type lipoxygenase 3 (EC 1.13.11.-) (e-LOX-3).

LX15B_MOUSE
θ value	4.7686e-118 (rank : 9)	NC score	0.972729 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	O35936	Gene names	Alox15b, Alox8
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (8S- lipoxygenase) (8S-LOX).

LX12B_HUMAN
θ value	6.228e-118 (rank : 10)	NC score	0.968949 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	O75342	Gene names	ALOX12B
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX).

LOXE3_MOUSE
θ value	2.89301e-115 (rank : 11)	NC score	0.968863 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WV07	Gene names	Aloxe3
Domain Architecture
Description	Epidermis-type lipoxygenase 3 (EC 1.13.11.-) (e-LOX-3).

LX12B_MOUSE
θ value	1.43579e-114 (rank : 12)	NC score	0.968746 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	O70582	Gene names	Alox12b, Aloxe2
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX) (Epidermis-type lipoxygenase 2) (e-LOX 2).

LX15B_HUMAN
θ value	3.1986e-114 (rank : 13)	NC score	0.971899 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	O15296, Q8IYQ2, Q8TEV3, Q8TEV4, Q8TEV5, Q8TEV6, Q9UKM4	Gene names	ALOX15B
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (15- lipoxygenase 2).

EP300_HUMAN
θ value	3.0926 (rank : 14)	NC score	0.005356 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	821	Shared Neighborhood Hits	3
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ALMS1_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.005535 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	356	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

DPOG1_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.006584 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P54099, Q9JI28	Gene names	Polg, Polg1
Domain Architecture
Description	DNA polymerase subunit gamma 1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha).

FA11_MOUSE
θ value	8.99809 (rank : 17)	NC score	-0.000008 (rank : 20)
Query Neighborhood Hits	18	Target Neighborhood Hits	180	Shared Neighborhood Hits	2
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

ITAV_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.002253 (rank : 19)
Query Neighborhood Hits	18	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	P43406	Gene names	Itgav
Domain Architecture
Description	Integrin alpha-V precursor (Vitronectin receptor subunit alpha) (CD51 antigen) [Contains: Integrin alpha-V heavy chain; Integrin alpha-V light chain].

PKDRE_HUMAN
θ value	θ > 10 (rank : 19)	NC score	0.066564 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PKDRE_MOUSE
θ value	θ > 10 (rank : 20)	NC score	0.125575 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	76	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

Hits sorted by NC score

LOX15_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	P16050, Q8N6R7, Q99657	Gene names	ALOX15, LOG15
Domain Architecture
Description	Arachidonate 15-lipoxygenase (EC 1.13.11.33) (Arachidonate omega-6 lipoxygenase) (15-LOX).

LX12L_MOUSE
NC score	0.999000 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	P39654, Q4FJY9, Q5F2E3, Q6PHB2	Gene names	Alox12l, Alox15
Domain Architecture
Description	Arachidonate 12-lipoxygenase, leukocyte-type (EC 1.13.11.31) (12-LOX).

LX12E_MOUSE
NC score	0.997774 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	P55249, Q91YW6	Gene names	Alox12e, Alox12-ps2, Aloxe
Domain Architecture
Description	Arachidonate 12-lipoxygenase, epidermal-type (EC 1.13.11.31) (12-LOX).

LOX12_MOUSE
NC score	0.997147 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	P39655, Q8BHG4	Gene names	Alox12, Alox12p
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

LOX12_HUMAN
NC score	0.997115 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	P18054, O95569, Q6ISF8, Q9UQM4	Gene names	ALOX12, LOG12
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

LOX5_MOUSE
NC score	0.973854 (rank : 6)	θ value	1.16911e-132 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	P48999	Gene names	Alox5
Domain Architecture
Description	Arachidonate 5-lipoxygenase (EC 1.13.11.34) (5-lipoxygenase) (5-LO).

LOX5_HUMAN
NC score	0.972757 (rank : 7)	θ value	2.60451e-132 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	P09917	Gene names	ALOX5, LOG5
Domain Architecture
Description	Arachidonate 5-lipoxygenase (EC 1.13.11.34) (5-lipoxygenase) (5-LO).

LX15B_MOUSE
NC score	0.972729 (rank : 8)	θ value	4.7686e-118 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	O35936	Gene names	Alox15b, Alox8
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (8S- lipoxygenase) (8S-LOX).

LX15B_HUMAN
NC score	0.971899 (rank : 9)	θ value	3.1986e-114 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	O15296, Q8IYQ2, Q8TEV3, Q8TEV4, Q8TEV5, Q8TEV6, Q9UKM4	Gene names	ALOX15B
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (15- lipoxygenase 2).

LOXE3_HUMAN
NC score	0.969934 (rank : 10)	θ value	6.01832e-121 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BYJ1, Q9H4F2, Q9HC22	Gene names	ALOXE3
Domain Architecture
Description	Epidermis-type lipoxygenase 3 (EC 1.13.11.-) (e-LOX-3).

LX12B_HUMAN
NC score	0.968949 (rank : 11)	θ value	6.228e-118 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	O75342	Gene names	ALOX12B
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX).

LOXE3_MOUSE
NC score	0.968863 (rank : 12)	θ value	2.89301e-115 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WV07	Gene names	Aloxe3
Domain Architecture
Description	Epidermis-type lipoxygenase 3 (EC 1.13.11.-) (e-LOX-3).

LX12B_MOUSE
NC score	0.968746 (rank : 13)	θ value	1.43579e-114 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	O70582	Gene names	Alox12b, Aloxe2
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX) (Epidermis-type lipoxygenase 2) (e-LOX 2).

PKDRE_MOUSE
NC score	0.125575 (rank : 14)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	18	Target Neighborhood Hits	76	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PKDRE_HUMAN
NC score	0.066564 (rank : 15)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	18	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

DPOG1_MOUSE
NC score	0.006584 (rank : 16)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P54099, Q9JI28	Gene names	Polg, Polg1
Domain Architecture
Description	DNA polymerase subunit gamma 1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha).

ALMS1_HUMAN
NC score	0.005535 (rank : 17)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	356	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

EP300_HUMAN
NC score	0.005356 (rank : 18)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	821	Shared Neighborhood Hits	3
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ITAV_MOUSE
NC score	0.002253 (rank : 19)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	P43406	Gene names	Itgav
Domain Architecture
Description	Integrin alpha-V precursor (Vitronectin receptor subunit alpha) (CD51 antigen) [Contains: Integrin alpha-V heavy chain; Integrin alpha-V light chain].

FA11_MOUSE
NC score	-0.000008 (rank : 20)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	180	Shared Neighborhood Hits	2
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].