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Network neighborhood for query Sequence : LOXE3_HUMAN

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LOXE3_HUMAN
SwissProt Accessions	Q9BYJ1, Q9H4F2, Q9HC22	Gene names	ALOXE3
Domain Architecture
Description	Epidermis-type lipoxygenase 3 (EC 1.13.11.-) (e-LOX-3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LOXE3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYJ1, Q9H4F2, Q9HC22	Gene names	ALOXE3
Domain Architecture
Description	Epidermis-type lipoxygenase 3 (EC 1.13.11.-) (e-LOX-3).

LOXE3_MOUSE
θ value	0 (rank : 2)	NC score	0.999589 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WV07	Gene names	Aloxe3
Domain Architecture
Description	Epidermis-type lipoxygenase 3 (EC 1.13.11.-) (e-LOX-3).

LX12B_HUMAN
θ value	0 (rank : 3)	NC score	0.994363 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	O75342	Gene names	ALOX12B
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX).

LX12B_MOUSE
θ value	0 (rank : 4)	NC score	0.994355 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	O70582	Gene names	Alox12b, Aloxe2
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX) (Epidermis-type lipoxygenase 2) (e-LOX 2).

LX15B_HUMAN
θ value	0 (rank : 5)	NC score	0.993215 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	O15296, Q8IYQ2, Q8TEV3, Q8TEV4, Q8TEV5, Q8TEV6, Q9UKM4	Gene names	ALOX15B
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (15- lipoxygenase 2).

LX15B_MOUSE
θ value	0 (rank : 6)	NC score	0.993246 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	O35936	Gene names	Alox15b, Alox8
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (8S- lipoxygenase) (8S-LOX).

LOX5_MOUSE
θ value	9.22056e-146 (rank : 7)	NC score	0.978438 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	P48999	Gene names	Alox5
Domain Architecture
Description	Arachidonate 5-lipoxygenase (EC 1.13.11.34) (5-lipoxygenase) (5-LO).

LOX5_HUMAN
θ value	2.05413e-145 (rank : 8)	NC score	0.977136 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	P09917	Gene names	ALOX5, LOG5
Domain Architecture
Description	Arachidonate 5-lipoxygenase (EC 1.13.11.34) (5-lipoxygenase) (5-LO).

LOX12_HUMAN
θ value	7.09276e-130 (rank : 9)	NC score	0.973194 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	P18054, O95569, Q6ISF8, Q9UQM4	Gene names	ALOX12, LOG12
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

LOX12_MOUSE
θ value	5.61992e-127 (rank : 10)	NC score	0.972391 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	P39655, Q8BHG4	Gene names	Alox12, Alox12p
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

LX12L_MOUSE
θ value	2.70151e-121 (rank : 11)	NC score	0.971536 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	14
SwissProt Accessions	P39654, Q4FJY9, Q5F2E3, Q6PHB2	Gene names	Alox12l, Alox15
Domain Architecture
Description	Arachidonate 12-lipoxygenase, leukocyte-type (EC 1.13.11.31) (12-LOX).

LOX15_HUMAN
θ value	6.01832e-121 (rank : 12)	NC score	0.969934 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	P16050, Q8N6R7, Q99657	Gene names	ALOX15, LOG15
Domain Architecture
Description	Arachidonate 15-lipoxygenase (EC 1.13.11.33) (Arachidonate omega-6 lipoxygenase) (15-LOX).

LX12E_MOUSE
θ value	2.5344e-111 (rank : 13)	NC score	0.968430 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	P55249, Q91YW6	Gene names	Alox12e, Alox12-ps2, Aloxe
Domain Architecture
Description	Arachidonate 12-lipoxygenase, epidermal-type (EC 1.13.11.31) (12-LOX).

PKDRE_MOUSE
θ value	0.163984 (rank : 14)	NC score	0.148842 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

K0133_HUMAN
θ value	3.0926 (rank : 15)	NC score	0.036364 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q14146	Gene names	KIAA0133
Domain Architecture	No domain graphic available
Description	Protein KIAA0133.

S28A2_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.011523 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	O43868, O43239	Gene names	SLC28A2, CNT2
Domain Architecture
Description	Sodium/nucleoside cotransporter 2 (Na(+)/nucleoside cotransporter 2) (Sodium-coupled nucleoside transporter 2) (Concentrative nucleoside transporter 2) (CNT 2) (hCNT2) (Sodium/purine nucleoside co- transporter) (SPNT).

CD44_MOUSE
θ value	6.88961 (rank : 17)	NC score	0.007764 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	P15379, Q05732, Q61395, Q62060, Q62061, Q62062, Q62063, Q62408, Q62409, Q64296, Q99J14, Q9QYX8	Gene names	Cd44, Ly-24
Domain Architecture
Description	CD44 antigen precursor (Phagocytic glycoprotein 1) (PGP-1) (HUTCH-I) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (Hermes antigen) (Hyaluronate receptor) (Lymphocyte antigen Ly-24).

F13B_MOUSE
θ value	6.88961 (rank : 18)	NC score	0.003581 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

SNX8_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.007221 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5X2, Q96I67	Gene names	SNX8
Domain Architecture
Description	Sorting nexin-8.

PKDRE_HUMAN
θ value	θ > 10 (rank : 20)	NC score	0.082312 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

Hits sorted by NC score

LOXE3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYJ1, Q9H4F2, Q9HC22	Gene names	ALOXE3
Domain Architecture
Description	Epidermis-type lipoxygenase 3 (EC 1.13.11.-) (e-LOX-3).

LOXE3_MOUSE
NC score	0.999589 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WV07	Gene names	Aloxe3
Domain Architecture
Description	Epidermis-type lipoxygenase 3 (EC 1.13.11.-) (e-LOX-3).

LX12B_HUMAN
NC score	0.994363 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	15
SwissProt Accessions	O75342	Gene names	ALOX12B
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX).

LX12B_MOUSE
NC score	0.994355 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	O70582	Gene names	Alox12b, Aloxe2
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX) (Epidermis-type lipoxygenase 2) (e-LOX 2).

LX15B_MOUSE
NC score	0.993246 (rank : 5)	θ value	0 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	O35936	Gene names	Alox15b, Alox8
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (8S- lipoxygenase) (8S-LOX).

LX15B_HUMAN
NC score	0.993215 (rank : 6)	θ value	0 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	O15296, Q8IYQ2, Q8TEV3, Q8TEV4, Q8TEV5, Q8TEV6, Q9UKM4	Gene names	ALOX15B
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (15- lipoxygenase 2).

LOX5_MOUSE
NC score	0.978438 (rank : 7)	θ value	9.22056e-146 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	P48999	Gene names	Alox5
Domain Architecture
Description	Arachidonate 5-lipoxygenase (EC 1.13.11.34) (5-lipoxygenase) (5-LO).

LOX5_HUMAN
NC score	0.977136 (rank : 8)	θ value	2.05413e-145 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	P09917	Gene names	ALOX5, LOG5
Domain Architecture
Description	Arachidonate 5-lipoxygenase (EC 1.13.11.34) (5-lipoxygenase) (5-LO).

LOX12_HUMAN
NC score	0.973194 (rank : 9)	θ value	7.09276e-130 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	P18054, O95569, Q6ISF8, Q9UQM4	Gene names	ALOX12, LOG12
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

LOX12_MOUSE
NC score	0.972391 (rank : 10)	θ value	5.61992e-127 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	P39655, Q8BHG4	Gene names	Alox12, Alox12p
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

LX12L_MOUSE
NC score	0.971536 (rank : 11)	θ value	2.70151e-121 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	14
SwissProt Accessions	P39654, Q4FJY9, Q5F2E3, Q6PHB2	Gene names	Alox12l, Alox15
Domain Architecture
Description	Arachidonate 12-lipoxygenase, leukocyte-type (EC 1.13.11.31) (12-LOX).

LOX15_HUMAN
NC score	0.969934 (rank : 12)	θ value	6.01832e-121 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	P16050, Q8N6R7, Q99657	Gene names	ALOX15, LOG15
Domain Architecture
Description	Arachidonate 15-lipoxygenase (EC 1.13.11.33) (Arachidonate omega-6 lipoxygenase) (15-LOX).

LX12E_MOUSE
NC score	0.968430 (rank : 13)	θ value	2.5344e-111 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	P55249, Q91YW6	Gene names	Alox12e, Alox12-ps2, Aloxe
Domain Architecture
Description	Arachidonate 12-lipoxygenase, epidermal-type (EC 1.13.11.31) (12-LOX).

PKDRE_MOUSE
NC score	0.148842 (rank : 14)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PKDRE_HUMAN
NC score	0.082312 (rank : 15)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

K0133_HUMAN
NC score	0.036364 (rank : 16)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	Q14146	Gene names	KIAA0133
Domain Architecture	No domain graphic available
Description	Protein KIAA0133.

S28A2_HUMAN
NC score	0.011523 (rank : 17)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	O43868, O43239	Gene names	SLC28A2, CNT2
Domain Architecture
Description	Sodium/nucleoside cotransporter 2 (Na(+)/nucleoside cotransporter 2) (Sodium-coupled nucleoside transporter 2) (Concentrative nucleoside transporter 2) (CNT 2) (hCNT2) (Sodium/purine nucleoside co- transporter) (SPNT).

CD44_MOUSE
NC score	0.007764 (rank : 18)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	P15379, Q05732, Q61395, Q62060, Q62061, Q62062, Q62063, Q62408, Q62409, Q64296, Q99J14, Q9QYX8	Gene names	Cd44, Ly-24
Domain Architecture
Description	CD44 antigen precursor (Phagocytic glycoprotein 1) (PGP-1) (HUTCH-I) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (Hermes antigen) (Hyaluronate receptor) (Lymphocyte antigen Ly-24).

SNX8_HUMAN
NC score	0.007221 (rank : 19)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5X2, Q96I67	Gene names	SNX8
Domain Architecture
Description	Sorting nexin-8.

F13B_MOUSE
NC score	0.003581 (rank : 20)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).