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Network neighborhood for query Sequence : LOX12_HUMAN

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LOX12_HUMAN
SwissProt Accessions	P18054, O95569, Q6ISF8, Q9UQM4	Gene names	ALOX12, LOG12
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LOX12_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	P18054, O95569, Q6ISF8, Q9UQM4	Gene names	ALOX12, LOG12
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

LOX12_MOUSE
θ value	0 (rank : 2)	NC score	0.999185 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	24	Shared Neighborhood Hits	15
SwissProt Accessions	P39655, Q8BHG4	Gene names	Alox12, Alox12p
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

LOX15_HUMAN
θ value	0 (rank : 3)	NC score	0.997115 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	P16050, Q8N6R7, Q99657	Gene names	ALOX15, LOG15
Domain Architecture
Description	Arachidonate 15-lipoxygenase (EC 1.13.11.33) (Arachidonate omega-6 lipoxygenase) (15-LOX).

LX12E_MOUSE
θ value	0 (rank : 4)	NC score	0.995970 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	P55249, Q91YW6	Gene names	Alox12e, Alox12-ps2, Aloxe
Domain Architecture
Description	Arachidonate 12-lipoxygenase, epidermal-type (EC 1.13.11.31) (12-LOX).

LX12L_MOUSE
θ value	0 (rank : 5)	NC score	0.996467 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	14
SwissProt Accessions	P39654, Q4FJY9, Q5F2E3, Q6PHB2	Gene names	Alox12l, Alox15
Domain Architecture
Description	Arachidonate 12-lipoxygenase, leukocyte-type (EC 1.13.11.31) (12-LOX).

LOX5_HUMAN
θ value	3.7522e-139 (rank : 6)	NC score	0.975644 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	P09917	Gene names	ALOX5, LOG5
Domain Architecture
Description	Arachidonate 5-lipoxygenase (EC 1.13.11.34) (5-lipoxygenase) (5-LO).

LOX5_MOUSE
θ value	5.6069e-135 (rank : 7)	NC score	0.976485 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	P48999	Gene names	Alox5
Domain Architecture
Description	Arachidonate 5-lipoxygenase (EC 1.13.11.34) (5-lipoxygenase) (5-LO).

LX12B_MOUSE
θ value	9.89713e-132 (rank : 8)	NC score	0.972960 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	O70582	Gene names	Alox12b, Aloxe2
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX) (Epidermis-type lipoxygenase 2) (e-LOX 2).

LX12B_HUMAN
θ value	4.15819e-130 (rank : 9)	NC score	0.973057 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	O75342	Gene names	ALOX12B
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX).

LOXE3_HUMAN
θ value	7.09276e-130 (rank : 10)	NC score	0.973194 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BYJ1, Q9H4F2, Q9HC22	Gene names	ALOXE3
Domain Architecture
Description	Epidermis-type lipoxygenase 3 (EC 1.13.11.-) (e-LOX-3).

LOXE3_MOUSE
θ value	1.99884e-124 (rank : 11)	NC score	0.972174 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WV07	Gene names	Aloxe3
Domain Architecture
Description	Epidermis-type lipoxygenase 3 (EC 1.13.11.-) (e-LOX-3).

LX15B_MOUSE
θ value	6.43005e-123 (rank : 12)	NC score	0.975248 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	O35936	Gene names	Alox15b, Alox8
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (8S- lipoxygenase) (8S-LOX).

LX15B_HUMAN
θ value	8.99321e-117 (rank : 13)	NC score	0.974279 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	O15296, Q8IYQ2, Q8TEV3, Q8TEV4, Q8TEV5, Q8TEV6, Q9UKM4	Gene names	ALOX15B
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (15- lipoxygenase 2).

PKDRE_MOUSE
θ value	0.47712 (rank : 14)	NC score	0.138467 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

SON_HUMAN
θ value	0.813845 (rank : 15)	NC score	0.009219 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	1568	Shared Neighborhood Hits	3
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SON_MOUSE
θ value	0.813845 (rank : 16)	NC score	0.016403 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	957	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

CHCH5_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.023378 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BSY4	Gene names	CHCHD5
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 5.

MTCPB_HUMAN
θ value	6.88961 (rank : 18)	NC score	0.012996 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P56278	Gene names	MTCP1, C6.1B
Domain Architecture
Description	P13 MTCP-1 protein (Mature T-cell proliferation-1 type B1) (MTCP-1 type B1) (P13MTCP1).

MTCPB_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.011700 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q60945	Gene names	Mtcp1, C6.1b
Domain Architecture
Description	P13 MTCP-1 protein (Mature T-cell proliferation-1 type B1) (MTCP-1 type B1) (P13MTCP1).

PKDRE_HUMAN
θ value	θ > 10 (rank : 20)	NC score	0.076807 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

Hits sorted by NC score

LOX12_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	P18054, O95569, Q6ISF8, Q9UQM4	Gene names	ALOX12, LOG12
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

LOX12_MOUSE
NC score	0.999185 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	24	Shared Neighborhood Hits	15
SwissProt Accessions	P39655, Q8BHG4	Gene names	Alox12, Alox12p
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12S-type (EC 1.13.11.31) (12-LOX) (Platelet-type lipoxygenase 12).

LOX15_HUMAN
NC score	0.997115 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	13
SwissProt Accessions	P16050, Q8N6R7, Q99657	Gene names	ALOX15, LOG15
Domain Architecture
Description	Arachidonate 15-lipoxygenase (EC 1.13.11.33) (Arachidonate omega-6 lipoxygenase) (15-LOX).

LX12L_MOUSE
NC score	0.996467 (rank : 4)	θ value	0 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	14
SwissProt Accessions	P39654, Q4FJY9, Q5F2E3, Q6PHB2	Gene names	Alox12l, Alox15
Domain Architecture
Description	Arachidonate 12-lipoxygenase, leukocyte-type (EC 1.13.11.31) (12-LOX).

LX12E_MOUSE
NC score	0.995970 (rank : 5)	θ value	0 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	P55249, Q91YW6	Gene names	Alox12e, Alox12-ps2, Aloxe
Domain Architecture
Description	Arachidonate 12-lipoxygenase, epidermal-type (EC 1.13.11.31) (12-LOX).

LOX5_MOUSE
NC score	0.976485 (rank : 6)	θ value	5.6069e-135 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	P48999	Gene names	Alox5
Domain Architecture
Description	Arachidonate 5-lipoxygenase (EC 1.13.11.34) (5-lipoxygenase) (5-LO).

LOX5_HUMAN
NC score	0.975644 (rank : 7)	θ value	3.7522e-139 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	P09917	Gene names	ALOX5, LOG5
Domain Architecture
Description	Arachidonate 5-lipoxygenase (EC 1.13.11.34) (5-lipoxygenase) (5-LO).

LX15B_MOUSE
NC score	0.975248 (rank : 8)	θ value	6.43005e-123 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	O35936	Gene names	Alox15b, Alox8
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (8S- lipoxygenase) (8S-LOX).

LX15B_HUMAN
NC score	0.974279 (rank : 9)	θ value	8.99321e-117 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	O15296, Q8IYQ2, Q8TEV3, Q8TEV4, Q8TEV5, Q8TEV6, Q9UKM4	Gene names	ALOX15B
Domain Architecture
Description	Arachidonate 15-lipoxygenase type II (EC 1.13.11.33) (15-LOX-2) (15- lipoxygenase 2).

LOXE3_HUMAN
NC score	0.973194 (rank : 10)	θ value	7.09276e-130 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BYJ1, Q9H4F2, Q9HC22	Gene names	ALOXE3
Domain Architecture
Description	Epidermis-type lipoxygenase 3 (EC 1.13.11.-) (e-LOX-3).

LX12B_HUMAN
NC score	0.973057 (rank : 11)	θ value	4.15819e-130 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	O75342	Gene names	ALOX12B
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX).

LX12B_MOUSE
NC score	0.972960 (rank : 12)	θ value	9.89713e-132 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	O70582	Gene names	Alox12b, Aloxe2
Domain Architecture
Description	Arachidonate 12-lipoxygenase, 12R type (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) (12R-lipoxygenase) (12R-LOX) (Epidermis-type lipoxygenase 2) (e-LOX 2).

LOXE3_MOUSE
NC score	0.972174 (rank : 13)	θ value	1.99884e-124 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WV07	Gene names	Aloxe3
Domain Architecture
Description	Epidermis-type lipoxygenase 3 (EC 1.13.11.-) (e-LOX-3).

PKDRE_MOUSE
NC score	0.138467 (rank : 14)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PKDRE_HUMAN
NC score	0.076807 (rank : 15)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

CHCH5_HUMAN
NC score	0.023378 (rank : 16)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BSY4	Gene names	CHCHD5
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 5.

SON_MOUSE
NC score	0.016403 (rank : 17)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	957	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

MTCPB_HUMAN
NC score	0.012996 (rank : 18)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	P56278	Gene names	MTCP1, C6.1B
Domain Architecture
Description	P13 MTCP-1 protein (Mature T-cell proliferation-1 type B1) (MTCP-1 type B1) (P13MTCP1).

MTCPB_MOUSE
NC score	0.011700 (rank : 19)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q60945	Gene names	Mtcp1, C6.1b
Domain Architecture
Description	P13 MTCP-1 protein (Mature T-cell proliferation-1 type B1) (MTCP-1 type B1) (P13MTCP1).

SON_HUMAN
NC score	0.009219 (rank : 20)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	1568	Shared Neighborhood Hits	3
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).