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Network neighborhood for query Sequence : GCH1_HUMAN

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GCH1_HUMAN
SwissProt Accessions	P30793, Q9Y4I8	Gene names	GCH1, DYT5, GCH
Domain Architecture
Description	GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GCH1_HUMAN
θ value	2.51683e-135 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	P30793, Q9Y4I8	Gene names	GCH1, DYT5, GCH
Domain Architecture
Description	GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I).

GCH1_MOUSE
θ value	1.21547e-113 (rank : 2)	NC score	0.965176 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q05915	Gene names	Gch1, Gch
Domain Architecture
Description	GTP cyclohydrolase I precursor (EC 3.5.4.16) (GTP-CH-I).

RECQ5_HUMAN
θ value	0.00390308 (rank : 3)	NC score	0.098180 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	390	Shared Neighborhood Hits	24
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

UBP51_HUMAN
θ value	0.0193708 (rank : 4)	NC score	0.045159 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	162	Shared Neighborhood Hits	6
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

SET1A_HUMAN
θ value	0.0431538 (rank : 5)	NC score	0.060008 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	690	Shared Neighborhood Hits	8
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

ATBF1_MOUSE
θ value	0.47712 (rank : 6)	NC score	0.025657 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	1841	Shared Neighborhood Hits	19
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ZN206_HUMAN
θ value	0.47712 (rank : 7)	NC score	0.007273 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	853	Shared Neighborhood Hits	14
SwissProt Accessions	Q96SZ4	Gene names	ZNF206, ZSCAN10
Domain Architecture	No domain graphic available
Description	Zinc finger protein 206 (Zinc finger and SCAN domain-containing protein 10).

SORC3_HUMAN
θ value	0.62314 (rank : 8)	NC score	0.048175 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPU3, Q5VXF9, Q9NQJ2	Gene names	SORCS3, KIAA1059
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

SORC3_MOUSE
θ value	0.62314 (rank : 9)	NC score	0.048251 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VI51, Q9CTR4	Gene names	Sorcs3
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

CO6A1_MOUSE
θ value	0.813845 (rank : 10)	NC score	0.025624 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	241	Shared Neighborhood Hits	9
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

KLF13_HUMAN
θ value	0.813845 (rank : 11)	NC score	0.013196 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	739	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2Y9, Q9Y356	Gene names	KLF13, BTEB3, NSLP1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Transcription factor NSLP1) (Novel Sp1-like zinc finger transcription factor 1).

KLH17_MOUSE
θ value	0.813845 (rank : 12)	NC score	0.019525 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	200	Shared Neighborhood Hits	3
SwissProt Accessions	Q6TDP3	Gene names	Klhl17
Domain Architecture	No domain graphic available
Description	Kelch-like protein 17 (Actinfilin).

MYPC2_HUMAN
θ value	0.813845 (rank : 13)	NC score	0.022418 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	316	Shared Neighborhood Hits	3
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

KLH17_HUMAN
θ value	1.06291 (rank : 14)	NC score	0.019035 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	201	Shared Neighborhood Hits	3
SwissProt Accessions	Q6TDP4	Gene names	KLHL17
Domain Architecture	No domain graphic available
Description	Kelch-like protein 17 (Actinfilin).

PRP1_HUMAN
θ value	1.06291 (rank : 15)	NC score	0.037389 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	385	Shared Neighborhood Hits	12
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SOX8_HUMAN
θ value	1.06291 (rank : 16)	NC score	0.019848 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

YLPM1_HUMAN
θ value	1.06291 (rank : 17)	NC score	0.045740 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	670	Shared Neighborhood Hits	13
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

PABP2_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.037380 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	212	Shared Neighborhood Hits	4
SwissProt Accessions	Q86U42, O43484	Gene names	PABPN1, PAB2, PABP2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

CBLB_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.036143 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	261	Shared Neighborhood Hits	7
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

ARHGB_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.018240 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	375	Shared Neighborhood Hits	5
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

BASP_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.032554 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	321	Shared Neighborhood Hits	5
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

ELOA3_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.031788 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

HCN2_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.014990 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	369	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

KLF13_MOUSE
θ value	2.36792 (rank : 24)	NC score	0.011557 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	757	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JJZ6, Q9ESX3, Q9JHF8	Gene names	Klf13, Bteb3, Fklf2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Erythroid transcription factor FKLF-2).

PTN23_HUMAN
θ value	2.36792 (rank : 25)	NC score	0.014307 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	646	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SDK1_HUMAN
θ value	2.36792 (rank : 26)	NC score	0.011083 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	511	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

TAF4_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.032458 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	687	Shared Neighborhood Hits	9
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

GSCR1_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.027191 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	674	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HES6_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.031612 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q96HZ4, Q8N2J2, Q96T93, Q9P2S3	Gene names	HES6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1).

LTBP4_MOUSE
θ value	3.0926 (rank : 30)	NC score	0.008378 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	607	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MMP16_HUMAN
θ value	3.0926 (rank : 31)	NC score	0.013683 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	P51512, Q14824, Q52H48	Gene names	MMP16, MMPX2
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP) (MMP- X2).

NPAS1_MOUSE
θ value	3.0926 (rank : 32)	NC score	0.016783 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

PRB4S_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.025673 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	330	Shared Neighborhood Hits	8
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

SCND1_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.019334 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	P57086	Gene names	SCAND1, SDP1
Domain Architecture
Description	SCAN domain-containing protein 1.

WASF3_MOUSE
θ value	3.0926 (rank : 35)	NC score	0.021354 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

BAT2_HUMAN
θ value	4.03905 (rank : 36)	NC score	0.040084 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	931	Shared Neighborhood Hits	22
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CBLB_MOUSE
θ value	4.03905 (rank : 37)	NC score	0.032775 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	277	Shared Neighborhood Hits	5
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CCD96_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.014862 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	595	Shared Neighborhood Hits	4
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

DCAK3_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.001155 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	888	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C098	Gene names	DCAMKL3, KIAA1765
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3).

KLF14_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.009902 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	725	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TD94	Gene names	KLF14, BTEB5
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 14 (Transcription factor BTEB5) (Basic transcription element-binding protein 5) (BTE-binding protein 5).

PRB3_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.030203 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	318	Shared Neighborhood Hits	11
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRPE_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.081480 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

3BP2_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.033419 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	296	Shared Neighborhood Hits	11
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ACRO_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.004624 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	291	Shared Neighborhood Hits	5
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

COHA1_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.021792 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	400	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CONA1_MOUSE
θ value	5.27518 (rank : 46)	NC score	0.017351 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	254	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

FOXGB_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.007891 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	148	Shared Neighborhood Hits	2
SwissProt Accessions	Q60987, Q80VP3	Gene names	Foxg1b, Fkhl1, Foxg1, Hfhbf1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1).

NFAC4_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.016575 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

SEN15_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.030829 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3W5, Q9CQW8, Q9CYI5	Gene names	Tsen15, Sen15
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen15 (tRNA-intron endonuclease Sen15).

ZN575_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.005788 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	739	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XF7	Gene names	ZNF575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

ARTN_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.021206 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T4W7, O95441, O96030, Q6P6A3	Gene names	ARTN, EVN
Domain Architecture	No domain graphic available
Description	Artemin precursor (Enovin) (Neublastin).

ARVC_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.011595 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

BAI1_MOUSE
θ value	6.88961 (rank : 53)	NC score	0.009864 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	340	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAT2_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.042006 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	947	Shared Neighborhood Hits	25
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CLIC6_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.018161 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	289	Shared Neighborhood Hits	13
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

HES7_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.023209 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

JPH2_MOUSE
θ value	6.88961 (rank : 57)	NC score	0.015536 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

PAWR_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.028304 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	252	Shared Neighborhood Hits	3
SwissProt Accessions	Q96IZ0, O75796, Q6FHY9, Q8N700	Gene names	PAWR, PAR4
Domain Architecture	No domain graphic available
Description	PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4).

BAI1_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.009247 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	375	Shared Neighborhood Hits	3
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

COHA1_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.019248 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	414	Shared Neighborhood Hits	7
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

DDEF1_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.007249 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	592	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

H6ST3_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.016044 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZP7, Q5W0L0, Q68CW6	Gene names	HS6ST3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3).

HXA3_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.010046 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	535	Shared Neighborhood Hits	9
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

HXB4_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.006127 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	375	Shared Neighborhood Hits	5
SwissProt Accessions	P10284, Q3UZB4, Q4VBG0	Gene names	Hoxb4, Hox-2.6, Hoxb-4
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2.6).

HXD11_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.007430 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	376	Shared Neighborhood Hits	5
SwissProt Accessions	P23813	Gene names	Hoxd11, Hox-4.6, Hoxd-11
Domain Architecture
Description	Homeobox protein Hox-D11 (Hox-4.6) (Hox-5.5).

MMP16_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.011399 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTR0, Q9ERT6	Gene names	Mmp16
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP).

PABP2_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.027385 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CCS6, O35935	Gene names	Pabpn1, Pab2, Pabp2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

PRP5_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.045863 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

UTP18_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.013626 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	139	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5J1, Q9H4N6	Gene names	UTP18, WDR50
Domain Architecture
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

Hits sorted by NC score

GCH1_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.51683e-135 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	P30793, Q9Y4I8	Gene names	GCH1, DYT5, GCH
Domain Architecture
Description	GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I).

GCH1_MOUSE
NC score	0.965176 (rank : 2)	θ value	1.21547e-113 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q05915	Gene names	Gch1, Gch
Domain Architecture
Description	GTP cyclohydrolase I precursor (EC 3.5.4.16) (GTP-CH-I).

RECQ5_HUMAN
NC score	0.098180 (rank : 3)	θ value	0.00390308 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	390	Shared Neighborhood Hits	24
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

PRPE_HUMAN
NC score	0.081480 (rank : 4)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

SET1A_HUMAN
NC score	0.060008 (rank : 5)	θ value	0.0431538 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	690	Shared Neighborhood Hits	8
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SORC3_MOUSE
NC score	0.048251 (rank : 6)	θ value	0.62314 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VI51, Q9CTR4	Gene names	Sorcs3
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

SORC3_HUMAN
NC score	0.048175 (rank : 7)	θ value	0.62314 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPU3, Q5VXF9, Q9NQJ2	Gene names	SORCS3, KIAA1059
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

PRP5_HUMAN
NC score	0.045863 (rank : 8)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

YLPM1_HUMAN
NC score	0.045740 (rank : 9)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	670	Shared Neighborhood Hits	13
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

UBP51_HUMAN
NC score	0.045159 (rank : 10)	θ value	0.0193708 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	162	Shared Neighborhood Hits	6
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

BAT2_MOUSE
NC score	0.042006 (rank : 11)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	947	Shared Neighborhood Hits	25
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_HUMAN
NC score	0.040084 (rank : 12)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	931	Shared Neighborhood Hits	22
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PRP1_HUMAN
NC score	0.037389 (rank : 13)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	385	Shared Neighborhood Hits	12
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PABP2_HUMAN
NC score	0.037380 (rank : 14)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	212	Shared Neighborhood Hits	4
SwissProt Accessions	Q86U42, O43484	Gene names	PABPN1, PAB2, PABP2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

CBLB_HUMAN
NC score	0.036143 (rank : 15)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	261	Shared Neighborhood Hits	7
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

3BP2_HUMAN
NC score	0.033419 (rank : 16)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	296	Shared Neighborhood Hits	11
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

CBLB_MOUSE
NC score	0.032775 (rank : 17)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	277	Shared Neighborhood Hits	5
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

BASP_HUMAN
NC score	0.032554 (rank : 18)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	321	Shared Neighborhood Hits	5
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

TAF4_HUMAN
NC score	0.032458 (rank : 19)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	687	Shared Neighborhood Hits	9
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

ELOA3_HUMAN
NC score	0.031788 (rank : 20)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

HES6_HUMAN
NC score	0.031612 (rank : 21)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q96HZ4, Q8N2J2, Q96T93, Q9P2S3	Gene names	HES6
Domain Architecture	No domain graphic available
Description	Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1).

SEN15_MOUSE
NC score	0.030829 (rank : 22)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3W5, Q9CQW8, Q9CYI5	Gene names	Tsen15, Sen15
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen15 (tRNA-intron endonuclease Sen15).

PRB3_HUMAN
NC score	0.030203 (rank : 23)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	318	Shared Neighborhood Hits	11
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PAWR_HUMAN
NC score	0.028304 (rank : 24)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	252	Shared Neighborhood Hits	3
SwissProt Accessions	Q96IZ0, O75796, Q6FHY9, Q8N700	Gene names	PAWR, PAR4
Domain Architecture	No domain graphic available
Description	PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4).

PABP2_MOUSE
NC score	0.027385 (rank : 25)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CCS6, O35935	Gene names	Pabpn1, Pab2, Pabp2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

GSCR1_HUMAN
NC score	0.027191 (rank : 26)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	674	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

PRB4S_HUMAN
NC score	0.025673 (rank : 27)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	330	Shared Neighborhood Hits	8
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

ATBF1_MOUSE
NC score	0.025657 (rank : 28)	θ value	0.47712 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	1841	Shared Neighborhood Hits	19
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CO6A1_MOUSE
NC score	0.025624 (rank : 29)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	241	Shared Neighborhood Hits	9
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

HES7_HUMAN
NC score	0.023209 (rank : 30)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

MYPC2_HUMAN
NC score	0.022418 (rank : 31)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	316	Shared Neighborhood Hits	3
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

COHA1_HUMAN
NC score	0.021792 (rank : 32)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	400	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

WASF3_MOUSE
NC score	0.021354 (rank : 33)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

ARTN_HUMAN
NC score	0.021206 (rank : 34)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T4W7, O95441, O96030, Q6P6A3	Gene names	ARTN, EVN
Domain Architecture	No domain graphic available
Description	Artemin precursor (Enovin) (Neublastin).

SOX8_HUMAN
NC score	0.019848 (rank : 35)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

KLH17_MOUSE
NC score	0.019525 (rank : 36)	θ value	0.813845 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	200	Shared Neighborhood Hits	3
SwissProt Accessions	Q6TDP3	Gene names	Klhl17
Domain Architecture	No domain graphic available
Description	Kelch-like protein 17 (Actinfilin).

SCND1_HUMAN
NC score	0.019334 (rank : 37)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	P57086	Gene names	SCAND1, SDP1
Domain Architecture
Description	SCAN domain-containing protein 1.

COHA1_MOUSE
NC score	0.019248 (rank : 38)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	414	Shared Neighborhood Hits	7
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

KLH17_HUMAN
NC score	0.019035 (rank : 39)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	201	Shared Neighborhood Hits	3
SwissProt Accessions	Q6TDP4	Gene names	KLHL17
Domain Architecture	No domain graphic available
Description	Kelch-like protein 17 (Actinfilin).

ARHGB_HUMAN
NC score	0.018240 (rank : 40)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	375	Shared Neighborhood Hits	5
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

CLIC6_HUMAN
NC score	0.018161 (rank : 41)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	289	Shared Neighborhood Hits	13
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

CONA1_MOUSE
NC score	0.017351 (rank : 42)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	254	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

NPAS1_MOUSE
NC score	0.016783 (rank : 43)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NFAC4_HUMAN
NC score	0.016575 (rank : 44)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

H6ST3_HUMAN
NC score	0.016044 (rank : 45)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZP7, Q5W0L0, Q68CW6	Gene names	HS6ST3
Domain Architecture	No domain graphic available
Description	Heparan-sulfate 6-O-sulfotransferase 3 (EC 2.8.2.-) (HS6ST-3).

JPH2_MOUSE
NC score	0.015536 (rank : 46)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

HCN2_HUMAN
NC score	0.014990 (rank : 47)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	369	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CCD96_HUMAN
NC score	0.014862 (rank : 48)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	595	Shared Neighborhood Hits	4
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

PTN23_HUMAN
NC score	0.014307 (rank : 49)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	646	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

MMP16_HUMAN
NC score	0.013683 (rank : 50)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	P51512, Q14824, Q52H48	Gene names	MMP16, MMPX2
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP) (MMP- X2).

UTP18_HUMAN
NC score	0.013626 (rank : 51)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	139	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5J1, Q9H4N6	Gene names	UTP18, WDR50
Domain Architecture
Description	U3 small nucleolar RNA-associated protein 18 homolog (WD repeat protein 50).

KLF13_HUMAN
NC score	0.013196 (rank : 52)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	739	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2Y9, Q9Y356	Gene names	KLF13, BTEB3, NSLP1
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Transcription factor NSLP1) (Novel Sp1-like zinc finger transcription factor 1).

ARVC_HUMAN
NC score	0.011595 (rank : 53)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

KLF13_MOUSE
NC score	0.011557 (rank : 54)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	757	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JJZ6, Q9ESX3, Q9JHF8	Gene names	Klf13, Bteb3, Fklf2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Erythroid transcription factor FKLF-2).

MMP16_MOUSE
NC score	0.011399 (rank : 55)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTR0, Q9ERT6	Gene names	Mmp16
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP).

SDK1_HUMAN
NC score	0.011083 (rank : 56)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	511	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

HXA3_HUMAN
NC score	0.010046 (rank : 57)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	535	Shared Neighborhood Hits	9
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

KLF14_HUMAN
NC score	0.009902 (rank : 58)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	725	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TD94	Gene names	KLF14, BTEB5
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 14 (Transcription factor BTEB5) (Basic transcription element-binding protein 5) (BTE-binding protein 5).

BAI1_MOUSE
NC score	0.009864 (rank : 59)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	340	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_HUMAN
NC score	0.009247 (rank : 60)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	375	Shared Neighborhood Hits	3
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

LTBP4_MOUSE
NC score	0.008378 (rank : 61)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	607	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

FOXGB_MOUSE
NC score	0.007891 (rank : 62)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	148	Shared Neighborhood Hits	2
SwissProt Accessions	Q60987, Q80VP3	Gene names	Foxg1b, Fkhl1, Foxg1, Hfhbf1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1).

HXD11_MOUSE
NC score	0.007430 (rank : 63)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	376	Shared Neighborhood Hits	5
SwissProt Accessions	P23813	Gene names	Hoxd11, Hox-4.6, Hoxd-11
Domain Architecture
Description	Homeobox protein Hox-D11 (Hox-4.6) (Hox-5.5).

ZN206_HUMAN
NC score	0.007273 (rank : 64)	θ value	0.47712 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	853	Shared Neighborhood Hits	14
SwissProt Accessions	Q96SZ4	Gene names	ZNF206, ZSCAN10
Domain Architecture	No domain graphic available
Description	Zinc finger protein 206 (Zinc finger and SCAN domain-containing protein 10).

DDEF1_MOUSE
NC score	0.007249 (rank : 65)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	592	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

HXB4_MOUSE
NC score	0.006127 (rank : 66)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	375	Shared Neighborhood Hits	5
SwissProt Accessions	P10284, Q3UZB4, Q4VBG0	Gene names	Hoxb4, Hox-2.6, Hoxb-4
Domain Architecture
Description	Homeobox protein Hox-B4 (Hox-2.6).

ZN575_HUMAN
NC score	0.005788 (rank : 67)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	739	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XF7	Gene names	ZNF575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

ACRO_HUMAN
NC score	0.004624 (rank : 68)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	291	Shared Neighborhood Hits	5
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

DCAK3_HUMAN
NC score	0.001155 (rank : 69)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	888	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C098	Gene names	DCAMKL3, KIAA1765
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3).