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Network neighborhood for query Sequence : GCH1_MOUSE

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GCH1_MOUSE
SwissProt Accessions	Q05915	Gene names	Gch1, Gch
Domain Architecture
Description	GTP cyclohydrolase I precursor (EC 3.5.4.16) (GTP-CH-I).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GCH1_MOUSE
θ value	1.02419e-128 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	6	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	Q05915	Gene names	Gch1, Gch
Domain Architecture
Description	GTP cyclohydrolase I precursor (EC 3.5.4.16) (GTP-CH-I).

GCH1_HUMAN
θ value	1.21547e-113 (rank : 2)	NC score	0.965176 (rank : 2)
Query Neighborhood Hits	6	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	P30793, Q9Y4I8	Gene names	GCH1, DYT5, GCH
Domain Architecture
Description	GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I).

ANKS6_HUMAN
θ value	0.279714 (rank : 3)	NC score	0.025508 (rank : 5)
Query Neighborhood Hits	6	Target Neighborhood Hits	411	Shared Neighborhood Hits	2
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

RECQ5_HUMAN
θ value	1.06291 (rank : 4)	NC score	0.060151 (rank : 4)
Query Neighborhood Hits	6	Target Neighborhood Hits	390	Shared Neighborhood Hits	3
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

FGD2_HUMAN
θ value	1.38821 (rank : 5)	NC score	0.018114 (rank : 6)
Query Neighborhood Hits	6	Target Neighborhood Hits	151	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

NU214_HUMAN
θ value	8.99809 (rank : 6)	NC score	0.014029 (rank : 7)
Query Neighborhood Hits	6	Target Neighborhood Hits	657	Shared Neighborhood Hits	2
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PRPE_HUMAN
θ value	θ > 10 (rank : 7)	NC score	0.075153 (rank : 3)
Query Neighborhood Hits	6	Target Neighborhood Hits	44	Shared Neighborhood Hits	1
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

Hits sorted by NC score

GCH1_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.02419e-128 (rank : 1)
Query Neighborhood Hits	6	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	Q05915	Gene names	Gch1, Gch
Domain Architecture
Description	GTP cyclohydrolase I precursor (EC 3.5.4.16) (GTP-CH-I).

GCH1_HUMAN
NC score	0.965176 (rank : 2)	θ value	1.21547e-113 (rank : 2)
Query Neighborhood Hits	6	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	P30793, Q9Y4I8	Gene names	GCH1, DYT5, GCH
Domain Architecture
Description	GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I).

PRPE_HUMAN
NC score	0.075153 (rank : 3)	θ value	θ > 10 (rank : 7)
Query Neighborhood Hits	6	Target Neighborhood Hits	44	Shared Neighborhood Hits	1
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

RECQ5_HUMAN
NC score	0.060151 (rank : 4)	θ value	1.06291 (rank : 4)
Query Neighborhood Hits	6	Target Neighborhood Hits	390	Shared Neighborhood Hits	3
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

ANKS6_HUMAN
NC score	0.025508 (rank : 5)	θ value	0.279714 (rank : 3)
Query Neighborhood Hits	6	Target Neighborhood Hits	411	Shared Neighborhood Hits	2
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

FGD2_HUMAN
NC score	0.018114 (rank : 6)	θ value	1.38821 (rank : 5)
Query Neighborhood Hits	6	Target Neighborhood Hits	151	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

NU214_HUMAN
NC score	0.014029 (rank : 7)	θ value	8.99809 (rank : 6)
Query Neighborhood Hits	6	Target Neighborhood Hits	657	Shared Neighborhood Hits	2
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).