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Network neighborhood for query Sequence : DKC1_HUMAN

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DKC1_HUMAN
SwissProt Accessions	O60832, O43845, Q96G67, Q9Y505	Gene names	DKC1, NOLA4
Domain Architecture
Description	H/ACA ribonucleoprotein complex subunit 4 (EC 5.4.99.-) (Dyskerin) (Nucleolar protein family A member 4) (snoRNP protein DKC1) (Nopp140- associated protein of 57 kDa) (Nucleolar protein NAP57) (CBF5 homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DKC1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	O60832, O43845, Q96G67, Q9Y505	Gene names	DKC1, NOLA4
Domain Architecture
Description	H/ACA ribonucleoprotein complex subunit 4 (EC 5.4.99.-) (Dyskerin) (Nucleolar protein family A member 4) (snoRNP protein DKC1) (Nopp140- associated protein of 57 kDa) (Nucleolar protein NAP57) (CBF5 homolog).

DKC1_MOUSE
θ value	0 (rank : 2)	NC score	0.992923 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ESX5	Gene names	Dkc1
Domain Architecture	No domain graphic available
Description	H/ACA ribonucleoprotein complex subunit 4 (EC 5.4.99.-) (Dyskerin) (Nucleolar protein family A member 4) (snoRNP protein DKC1) (Nopp140- associated protein of 57 kDa) (Nucleolar protein NAP57).

TRUB1_MOUSE
θ value	1.74796e-11 (rank : 3)	NC score	0.469471 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C0D0, Q5EBH7, Q9D331	Gene names	Trub1
Domain Architecture	No domain graphic available
Description	Probable tRNA pseudouridine synthase 1 (EC 5.4.99.-).

TRUB1_HUMAN
θ value	6.64225e-11 (rank : 4)	NC score	0.464626 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWH5, Q53ES2	Gene names	TRUB1, PUS4
Domain Architecture	No domain graphic available
Description	Probable tRNA pseudouridine synthase 1 (EC 5.4.99.-).

UT14B_MOUSE
θ value	0.279714 (rank : 5)	NC score	0.051726 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	226	Shared Neighborhood Hits	8
SwissProt Accessions	Q6EJB6, Q6EJB5, Q8BL60	Gene names	Utp14b, Jsd
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein).

K1143_MOUSE
θ value	0.365318 (rank : 6)	NC score	0.069334 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K039, Q9CSR4, Q9D0W8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1143 homolog.

IWS1_MOUSE
θ value	0.47712 (rank : 7)	NC score	0.025650 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	1258	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IGEB_MOUSE
θ value	0.62314 (rank : 8)	NC score	0.038973 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P03975	Gene names	Iap
Domain Architecture
Description	IgE-binding protein.

MTA70_HUMAN
θ value	0.62314 (rank : 9)	NC score	0.047480 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q86U44, O14736, Q86V05, Q9HB32	Gene names	METTL3, MTA70
Domain Architecture
Description	N6-adenosine-methyltransferase 70 kDa subunit (EC 2.1.1.62) (MT-A70) (Methyltransferase-like protein 3).

CD2L5_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.003411 (rank : 25)
Query Neighborhood Hits	24	Target Neighborhood Hits	987	Shared Neighborhood Hits	2
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

CDN1C_MOUSE
θ value	2.36792 (rank : 11)	NC score	0.034653 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

ELOA1_MOUSE
θ value	2.36792 (rank : 12)	NC score	0.025436 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	152	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

ZN318_MOUSE
θ value	2.36792 (rank : 13)	NC score	0.025571 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	642	Shared Neighborhood Hits	7
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

GP108_MOUSE
θ value	3.0926 (rank : 14)	NC score	0.023375 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WD0, Q8BXE9, Q925B1	Gene names	Gpr108, Lustr2
Domain Architecture	No domain graphic available
Description	Protein GPR108 precursor (Lung seven transmembrane receptor 2).

PESC_MOUSE
θ value	3.0926 (rank : 15)	NC score	0.029627 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQ61, Q542F0	Gene names	Pes1
Domain Architecture
Description	Pescadillo homolog 1.

TTF1_MOUSE
θ value	3.0926 (rank : 16)	NC score	0.027667 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	277	Shared Neighborhood Hits	4
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

SHE_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.016374 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	164	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

ANK3_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.006309 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	853	Shared Neighborhood Hits	7
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

MYST4_HUMAN
θ value	5.27518 (rank : 19)	NC score	0.012242 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	671	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

PCLO_HUMAN
θ value	5.27518 (rank : 20)	NC score	0.009628 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	2046	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PLRG1_MOUSE
θ value	5.27518 (rank : 21)	NC score	0.006822 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	308	Shared Neighborhood Hits	2
SwissProt Accessions	Q922V4, O55039	Gene names	Plrg1
Domain Architecture
Description	Pleiotropic regulator 1.

ALO17_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.016960 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	317	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

ALS2_MOUSE
θ value	8.99809 (rank : 23)	NC score	0.009793 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

CING_MOUSE
θ value	8.99809 (rank : 24)	NC score	0.002875 (rank : 26)
Query Neighborhood Hits	24	Target Neighborhood Hits	1432	Shared Neighborhood Hits	6
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

TRUB2_HUMAN
θ value	θ > 10 (rank : 25)	NC score	0.103367 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	O95900	Gene names	TRUB2
Domain Architecture	No domain graphic available
Description	Probable tRNA pseudouridine synthase 2 (EC 5.4.99.-).

TRUB2_MOUSE
θ value	θ > 10 (rank : 26)	NC score	0.100461 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WG3, Q8BTK3	Gene names	Trub2
Domain Architecture	No domain graphic available
Description	Probable tRNA pseudouridine synthase 2 (EC 5.4.99.-).

Hits sorted by NC score

DKC1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	O60832, O43845, Q96G67, Q9Y505	Gene names	DKC1, NOLA4
Domain Architecture
Description	H/ACA ribonucleoprotein complex subunit 4 (EC 5.4.99.-) (Dyskerin) (Nucleolar protein family A member 4) (snoRNP protein DKC1) (Nopp140- associated protein of 57 kDa) (Nucleolar protein NAP57) (CBF5 homolog).

DKC1_MOUSE
NC score	0.992923 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ESX5	Gene names	Dkc1
Domain Architecture	No domain graphic available
Description	H/ACA ribonucleoprotein complex subunit 4 (EC 5.4.99.-) (Dyskerin) (Nucleolar protein family A member 4) (snoRNP protein DKC1) (Nopp140- associated protein of 57 kDa) (Nucleolar protein NAP57).

TRUB1_MOUSE
NC score	0.469471 (rank : 3)	θ value	1.74796e-11 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C0D0, Q5EBH7, Q9D331	Gene names	Trub1
Domain Architecture	No domain graphic available
Description	Probable tRNA pseudouridine synthase 1 (EC 5.4.99.-).

TRUB1_HUMAN
NC score	0.464626 (rank : 4)	θ value	6.64225e-11 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWH5, Q53ES2	Gene names	TRUB1, PUS4
Domain Architecture	No domain graphic available
Description	Probable tRNA pseudouridine synthase 1 (EC 5.4.99.-).

TRUB2_HUMAN
NC score	0.103367 (rank : 5)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	24	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	O95900	Gene names	TRUB2
Domain Architecture	No domain graphic available
Description	Probable tRNA pseudouridine synthase 2 (EC 5.4.99.-).

TRUB2_MOUSE
NC score	0.100461 (rank : 6)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	24	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WG3, Q8BTK3	Gene names	Trub2
Domain Architecture	No domain graphic available
Description	Probable tRNA pseudouridine synthase 2 (EC 5.4.99.-).

K1143_MOUSE
NC score	0.069334 (rank : 7)	θ value	0.365318 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K039, Q9CSR4, Q9D0W8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1143 homolog.

UT14B_MOUSE
NC score	0.051726 (rank : 8)	θ value	0.279714 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	226	Shared Neighborhood Hits	8
SwissProt Accessions	Q6EJB6, Q6EJB5, Q8BL60	Gene names	Utp14b, Jsd
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein).

MTA70_HUMAN
NC score	0.047480 (rank : 9)	θ value	0.62314 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q86U44, O14736, Q86V05, Q9HB32	Gene names	METTL3, MTA70
Domain Architecture
Description	N6-adenosine-methyltransferase 70 kDa subunit (EC 2.1.1.62) (MT-A70) (Methyltransferase-like protein 3).

IGEB_MOUSE
NC score	0.038973 (rank : 10)	θ value	0.62314 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P03975	Gene names	Iap
Domain Architecture
Description	IgE-binding protein.

CDN1C_MOUSE
NC score	0.034653 (rank : 11)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

PESC_MOUSE
NC score	0.029627 (rank : 12)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQ61, Q542F0	Gene names	Pes1
Domain Architecture
Description	Pescadillo homolog 1.

TTF1_MOUSE
NC score	0.027667 (rank : 13)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	277	Shared Neighborhood Hits	4
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

IWS1_MOUSE
NC score	0.025650 (rank : 14)	θ value	0.47712 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	1258	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ZN318_MOUSE
NC score	0.025571 (rank : 15)	θ value	2.36792 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	642	Shared Neighborhood Hits	7
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

ELOA1_MOUSE
NC score	0.025436 (rank : 16)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	152	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

GP108_MOUSE
NC score	0.023375 (rank : 17)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WD0, Q8BXE9, Q925B1	Gene names	Gpr108, Lustr2
Domain Architecture	No domain graphic available
Description	Protein GPR108 precursor (Lung seven transmembrane receptor 2).

ALO17_HUMAN
NC score	0.016960 (rank : 18)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	317	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

SHE_HUMAN
NC score	0.016374 (rank : 19)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	164	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

MYST4_HUMAN
NC score	0.012242 (rank : 20)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	671	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

ALS2_MOUSE
NC score	0.009793 (rank : 21)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q920R0, Q8JZR1, Q9CXJ3	Gene names	Als2
Domain Architecture
Description	Alsin (Amyotrophic lateral sclerosis protein 2 homolog).

PCLO_HUMAN
NC score	0.009628 (rank : 22)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	2046	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PLRG1_MOUSE
NC score	0.006822 (rank : 23)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	308	Shared Neighborhood Hits	2
SwissProt Accessions	Q922V4, O55039	Gene names	Plrg1
Domain Architecture
Description	Pleiotropic regulator 1.

ANK3_HUMAN
NC score	0.006309 (rank : 24)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	853	Shared Neighborhood Hits	7
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

CD2L5_HUMAN
NC score	0.003411 (rank : 25)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	987	Shared Neighborhood Hits	2
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

CING_MOUSE
NC score	0.002875 (rank : 26)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	1432	Shared Neighborhood Hits	6
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.