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Network neighborhood for query Sequence : AP2M1_HUMAN

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AP2M1_HUMAN
SwissProt Accessions	Q96CW1, P20172, P53679	Gene names	AP2M1, CLAPM1, KIAA0109
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit mu-1 (Adaptin mu-1) (AP-2 mu-2 chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Plasma membrane adaptor AP-2 50 kDa protein) (HA2 50 kDa subunit) (Clathrin assembly protein complex 2 medium chain).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AP2M1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	Q96CW1, P20172, P53679	Gene names	AP2M1, CLAPM1, KIAA0109
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit mu-1 (Adaptin mu-1) (AP-2 mu-2 chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Plasma membrane adaptor AP-2 50 kDa protein) (HA2 50 kDa subunit) (Clathrin assembly protein complex 2 medium chain).

AP2M1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	P84091, P20172, P53679	Gene names	Ap2m1, Clapm1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit mu-1 (Adaptin mu-1) (AP-2 mu-2 chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Plasma membrane adaptor AP-2 50 kDa protein) (Clathrin assembly protein complex 2 medium chain).

AP1M2_MOUSE
θ value	7.66637e-92 (rank : 3)	NC score	0.967901 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WVP1, Q99LA4, Q9CWP7	Gene names	Ap1m2
Domain Architecture
Description	AP-1 complex subunit mu-2 (Adaptor-related protein complex 1 mu-2 subunit) (Mu-adaptin 2) (Adaptor protein complex AP-1 mu-2 subunit) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 2) (AP-mu chain family member mu1B).

AP1M2_HUMAN
θ value	8.47616e-91 (rank : 4)	NC score	0.967279 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6Q5, Q9BSI8	Gene names	AP1M2
Domain Architecture
Description	AP-1 complex subunit mu-2 (Adaptor-related protein complex 1 mu-2 subunit) (Mu-adaptin 2) (Adaptor protein complex AP-1 mu-2 subunit) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 2) (AP-mu chain family member mu1B).

AP1M1_HUMAN
θ value	7.17548e-90 (rank : 5)	NC score	0.965323 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BXS5	Gene names	AP1M1, CLTNM
Domain Architecture
Description	AP-1 complex subunit mu-1 (Adaptor-related protein complex 1 mu-1 subunit) (Mu-adaptin 1) (Adaptor protein complex AP-1 mu-1 subunit) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 1) (AP-mu chain family member mu1A) (Clathrin coat assembly protein AP47) (Clathrin coat- associated protein AP47).

AP1M1_MOUSE
θ value	1.59853e-89 (rank : 6)	NC score	0.965277 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	27
SwissProt Accessions	P35585	Gene names	Ap1m1, Cltnm
Domain Architecture
Description	AP-1 complex subunit mu-1 (Adaptor-related protein complex 1 mu-1 subunit) (Mu-adaptin 1) (Adaptor protein complex AP-1 mu-1 subunit) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 1) (AP-mu chain family member mu1A) (Clathrin coat assembly protein AP47) (Clathrin coat- associated protein AP47).

AP4M1_MOUSE
θ value	7.51208e-47 (rank : 7)	NC score	0.897869 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	23	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JKC7	Gene names	Ap4m1
Domain Architecture
Description	AP-4 complex subunit mu-1 (Adapter-related protein complex 4 mu-1 subunit) (Mu subunit of AP-4) (AP-4 adapter complex mu subunit) (Mu- adaptin-related protein 2) (mu-ARP2) (mu4).

AP4M1_HUMAN
θ value	6.35935e-46 (rank : 8)	NC score	0.902782 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	24
SwissProt Accessions	O00189, Q9UHK9	Gene names	AP4M1, MUARP2
Domain Architecture
Description	AP-4 complex subunit mu-1 (Adapter-related protein complex 4 mu-1 subunit) (Mu subunit of AP-4) (AP-4 adapter complex mu subunit) (Mu- adaptin-related protein 2) (mu-ARP2) (mu4).

AP3M1_HUMAN
θ value	8.89434e-40 (rank : 9)	NC score	0.853945 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y2T2	Gene names	AP3M1
Domain Architecture
Description	AP-3 complex subunit mu-1 (Adapter-related protein complex 3 mu-1 subunit) (Mu-adaptin 3A) (AP-3 adapter complex mu3A subunit).

AP3M1_MOUSE
θ value	1.16164e-39 (rank : 10)	NC score	0.853601 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JKC8, Q5BKQ6	Gene names	Ap3m1
Domain Architecture
Description	AP-3 complex subunit mu-1 (Adapter-related protein complex 3 mu-1 subunit) (Mu-adaptin 3A) (AP-3 adapter complex mu3A subunit).

AP3M2_HUMAN
θ value	2.19075e-38 (rank : 11)	NC score	0.845744 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	P53677	Gene names	AP3M2
Domain Architecture
Description	AP-3 complex subunit mu-2 (Adapter-related protein complex 3 mu-2 subunit) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Clathrin assembly protein assembly protein complex 1 medium chain homolog 2) (P47B).

AP3M2_MOUSE
θ value	1.08726e-37 (rank : 12)	NC score	0.845838 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R2R9, Q3UYJ3, Q923G7	Gene names	Ap3m2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit mu-2 (Adapter-related protein complex 3 mu-2 subunit) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Clathrin assembly protein assembly protein complex 1 medium chain homolog 2) (P47B) (m3B).

STON2_HUMAN
θ value	1.09485e-13 (rank : 13)	NC score	0.469648 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	115	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

STON2_MOUSE
θ value	1.09485e-13 (rank : 14)	NC score	0.462863 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	75	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BZ60	Gene names	Ston2, Stn2, Stnb
Domain Architecture
Description	Stonin-2 (Stoned B).

STON1_MOUSE
θ value	1.33837e-11 (rank : 15)	NC score	0.490571 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CDJ8, Q8CDL8, Q9D5T3	Gene names	Ston1, Salf, Sblf, Stn1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

STON1_HUMAN
θ value	3.64472e-09 (rank : 16)	NC score	0.468718 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	49	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6Q2, Q96JE3, Q9BYX3	Gene names	STON1, SALF, SBLF, STN1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

AP1S3_HUMAN
θ value	0.0193708 (rank : 17)	NC score	0.207818 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q96PC3, Q8WTY1, Q96DD1	Gene names	AP1S3
Domain Architecture
Description	AP-1 complex subunit sigma-3 (Adapter-related protein complex 1 sigma- 1C subunit) (Sigma-adaptin 1C) (Adaptor protein complex AP-1 sigma-1C subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1C subunit) (Clathrin assembly protein complex 1 sigma-1C small chain) (Sigma 1C subunit of AP-1 clathrin).

AP1S3_MOUSE
θ value	0.0736092 (rank : 18)	NC score	0.189776 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TN05	Gene names	Ap1s3
Domain Architecture	No domain graphic available
Description	AP-1 complex subunit sigma-3 (Adapter-related protein complex 1 sigma- 1C subunit) (Sigma-adaptin 1C) (Adaptor protein complex AP-1 sigma-1C subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1C subunit) (Clathrin assembly protein complex 1 sigma-1C small chain) (Sigma 1C subunit of AP-1 clathrin).

AP2S1_HUMAN
θ value	0.0736092 (rank : 19)	NC score	0.160393 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	P53680, O75977, Q6PK67	Gene names	AP2S1, AP17, CLAPS2
Domain Architecture
Description	AP-2 complex subunit sigma-1 (Adapter-related protein complex 2 sigma- 1 subunit) (Clathrin coat assembly protein AP17) (Clathrin coat- associated protein AP17) (Plasma membrane adaptor AP-2 17 kDa protein) (HA2 17 kDa subunit) (Clathrin assembly protein 2 small chain).

AP2S1_MOUSE
θ value	0.0736092 (rank : 20)	NC score	0.160393 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	P62743, P70626, P97626, Q00380	Gene names	Ap2s1, Ap17, Claps2
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit sigma-1 (Adapter-related protein complex 2 sigma- 1 subunit) (Sigma-adaptin 3b) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (Plasma membrane adaptor AP-2 17 kDa protein) (Clathrin assembly protein 2 small chain).

AP1S2_HUMAN
θ value	0.0961366 (rank : 21)	NC score	0.191179 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	P56377, O95326, Q9H2N6	Gene names	AP1S2
Domain Architecture
Description	AP-1 complex subunit sigma-2 (Adapter-related protein complex 1 sigma- 1B subunit) (Sigma-adaptin 1B) (Adaptor protein complex AP-1 sigma-1B subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Clathrin assembly protein complex 1 sigma-1B small chain) (Sigma 1B subunit of AP-1 clathrin).

AP1S2_MOUSE
θ value	0.0961366 (rank : 22)	NC score	0.194393 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	Q9DB50, Q543R7	Gene names	Ap1s2
Domain Architecture
Description	AP-1 complex subunit sigma-2 (Adapter-related protein complex 1 sigma- 1B subunit) (Sigma-adaptin 1B) (Adaptor protein complex AP-1 sigma-1B subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Clathrin assembly protein complex 1 sigma-1B small chain) (Sigma 1B subunit of AP-1 clathrin).

AP4S1_MOUSE
θ value	0.125558 (rank : 23)	NC score	0.168834 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WVL1	Gene names	Ap4s1
Domain Architecture
Description	AP-4 complex subunit sigma-1 (Adapter-related protein complex 4 sigma- 1 subunit) (Sigma subunit of AP-4) (AP-4 adapter complex sigma subunit).

AP1S1_HUMAN
θ value	0.163984 (rank : 24)	NC score	0.186226 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P61966, P82267, Q00382, Q9BTN4, Q9UDW9	Gene names	AP1S1, AP19, CLAPS1
Domain Architecture
Description	AP-1 complex subunit sigma-1A (Adapter-related protein complex 1 sigma-1A subunit) (Sigma-adaptin 1A) (Adaptor protein complex AP-1 sigma-1A subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathrin coat assembly protein AP19) (HA1 19 kDa subunit) (Sigma 1a subunit of AP-1 clathrin).

AP1S1_MOUSE
θ value	0.163984 (rank : 25)	NC score	0.186226 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P61967, P82267, Q00382, Q9BTN4, Q9UDW9	Gene names	Ap1s1, Ap19
Domain Architecture
Description	AP-1 complex subunit sigma-1A (Adapter-related protein complex 1 sigma-1A subunit) (Sigma-adaptin 1A) (Adaptor protein complex AP-1 sigma-1A subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathrin coat assembly protein AP19) (HA1 19 kDa subunit) (Sigma 1a subunit of AP-1 clathrin).

AP4S1_HUMAN
θ value	0.163984 (rank : 26)	NC score	0.191032 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y587	Gene names	AP4S1
Domain Architecture
Description	AP-4 complex subunit sigma-1 (Adapter-related protein complex 4 sigma- 1 subunit) (Sigma subunit of AP-4) (AP-4 adapter complex sigma subunit).

GBRA2_HUMAN
θ value	0.21417 (rank : 27)	NC score	0.018703 (rank : 35)
Query Neighborhood Hits	33	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	P47869	Gene names	GABRA2
Domain Architecture
Description	Gamma-aminobutyric-acid receptor subunit alpha-2 precursor (GABA(A) receptor subunit alpha-2).

GBRA1_MOUSE
θ value	4.03905 (rank : 28)	NC score	0.012359 (rank : 37)
Query Neighborhood Hits	33	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	P62812, P18504	Gene names	Gabra1, Gabra-1
Domain Architecture	No domain graphic available
Description	Gamma-aminobutyric-acid receptor subunit alpha-1 precursor (GABA(A) receptor subunit alpha-1).

GBRA2_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.012599 (rank : 36)
Query Neighborhood Hits	33	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	P26048	Gene names	Gabra2, Gabra-2
Domain Architecture
Description	Gamma-aminobutyric-acid receptor subunit alpha-2 precursor (GABA(A) receptor subunit alpha-2).

LRC33_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.007101 (rank : 38)
Query Neighborhood Hits	33	Target Neighborhood Hits	293	Shared Neighborhood Hits	3
SwissProt Accessions	Q86YC3	Gene names	LRRC33
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 33 precursor.

COPD_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.140744 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	40	Shared Neighborhood Hits	18
SwissProt Accessions	P48444, Q52M80	Gene names	ARCN1, COPD
Domain Architecture
Description	Coatomer subunit delta (Delta-coat protein) (Delta-COP) (Archain).

COPD_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.140736 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q5XJY5	Gene names	Arcn1, Copd
Domain Architecture	No domain graphic available
Description	Coatomer subunit delta (Delta-coat protein) (Delta-COP) (Archain).

CTGE2_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.003588 (rank : 39)
Query Neighborhood Hits	33	Target Neighborhood Hits	594	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

AP3S1_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.064303 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q92572, O00647, O00676, O00721, O00727, Q6ICQ2	Gene names	AP3S1, CLAPS3
Domain Architecture
Description	AP-3 complex subunit sigma-1 (Adapter-related protein complex 3 sigma- 1 subunit) (Sigma-adaptin 3a) (AP-3 complex sigma-3A subunit) (Sigma- 3A-adaptin) (Clathrin-associated/assembly/adapter protein, small 3).

AP3S1_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.064303 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DCR2, O88670	Gene names	Ap3s1
Domain Architecture
Description	AP-3 complex subunit sigma-1 (Adapter-related protein complex 3 sigma- 1 subunit) (Sigma-adaptin 3a) (AP-3 complex sigma-3A subunit) (Sigma- 3A-adaptin).

AP3S2_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.060722 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	P59780, O09077, O09149, Q99589	Gene names	AP3S2
Domain Architecture
Description	AP-3 complex subunit sigma-2 (Adapter-related protein complex 3 sigma- 2 subunit) (Sigma-adaptin 3b) (AP-3 complex sigma-3B subunit) (Sigma- 3B-adaptin).

AP3S2_MOUSE
θ value	θ > 10 (rank : 37)	NC score	0.060722 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BSZ2, O09077, O09149, Q3UDG7, Q8CAY1, Q99589	Gene names	Ap3s2
Domain Architecture
Description	AP-3 complex subunit sigma-2 (Adapter-related protein complex 3 sigma- 2 subunit) (Sigma-adaptin 3b) (AP-3 complex sigma-3B subunit) (Sigma- 3B-adaptin).

CN108_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.096866 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0R1, O95354, Q96DX3, Q9NVC5	Gene names	C14orf108
Domain Architecture
Description	Protein C14orf108 (Putative HIV-1 infection-related protein).

CN108_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.053509 (rank : 34)
Query Neighborhood Hits	33	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJ63, Q3TPT5, Q8BII2, Q8BJ31, Q8BJ58, Q8BY11, Q8R5B1	Gene names
Domain Architecture
Description	Protein C14orf108 homolog.

Hits sorted by NC score

AP2M1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	Q96CW1, P20172, P53679	Gene names	AP2M1, CLAPM1, KIAA0109
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit mu-1 (Adaptin mu-1) (AP-2 mu-2 chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Plasma membrane adaptor AP-2 50 kDa protein) (HA2 50 kDa subunit) (Clathrin assembly protein complex 2 medium chain).

AP2M1_MOUSE
NC score	0.999962 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	P84091, P20172, P53679	Gene names	Ap2m1, Clapm1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit mu-1 (Adaptin mu-1) (AP-2 mu-2 chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Plasma membrane adaptor AP-2 50 kDa protein) (Clathrin assembly protein complex 2 medium chain).

AP1M2_MOUSE
NC score	0.967901 (rank : 3)	θ value	7.66637e-92 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WVP1, Q99LA4, Q9CWP7	Gene names	Ap1m2
Domain Architecture
Description	AP-1 complex subunit mu-2 (Adaptor-related protein complex 1 mu-2 subunit) (Mu-adaptin 2) (Adaptor protein complex AP-1 mu-2 subunit) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 2) (AP-mu chain family member mu1B).

AP1M2_HUMAN
NC score	0.967279 (rank : 4)	θ value	8.47616e-91 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6Q5, Q9BSI8	Gene names	AP1M2
Domain Architecture
Description	AP-1 complex subunit mu-2 (Adaptor-related protein complex 1 mu-2 subunit) (Mu-adaptin 2) (Adaptor protein complex AP-1 mu-2 subunit) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 2) (AP-mu chain family member mu1B).

AP1M1_HUMAN
NC score	0.965323 (rank : 5)	θ value	7.17548e-90 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BXS5	Gene names	AP1M1, CLTNM
Domain Architecture
Description	AP-1 complex subunit mu-1 (Adaptor-related protein complex 1 mu-1 subunit) (Mu-adaptin 1) (Adaptor protein complex AP-1 mu-1 subunit) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 1) (AP-mu chain family member mu1A) (Clathrin coat assembly protein AP47) (Clathrin coat- associated protein AP47).

AP1M1_MOUSE
NC score	0.965277 (rank : 6)	θ value	1.59853e-89 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	27
SwissProt Accessions	P35585	Gene names	Ap1m1, Cltnm
Domain Architecture
Description	AP-1 complex subunit mu-1 (Adaptor-related protein complex 1 mu-1 subunit) (Mu-adaptin 1) (Adaptor protein complex AP-1 mu-1 subunit) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 1) (AP-mu chain family member mu1A) (Clathrin coat assembly protein AP47) (Clathrin coat- associated protein AP47).

AP4M1_HUMAN
NC score	0.902782 (rank : 7)	θ value	6.35935e-46 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	27	Shared Neighborhood Hits	24
SwissProt Accessions	O00189, Q9UHK9	Gene names	AP4M1, MUARP2
Domain Architecture
Description	AP-4 complex subunit mu-1 (Adapter-related protein complex 4 mu-1 subunit) (Mu subunit of AP-4) (AP-4 adapter complex mu subunit) (Mu- adaptin-related protein 2) (mu-ARP2) (mu4).

AP4M1_MOUSE
NC score	0.897869 (rank : 8)	θ value	7.51208e-47 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	23	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JKC7	Gene names	Ap4m1
Domain Architecture
Description	AP-4 complex subunit mu-1 (Adapter-related protein complex 4 mu-1 subunit) (Mu subunit of AP-4) (AP-4 adapter complex mu subunit) (Mu- adaptin-related protein 2) (mu-ARP2) (mu4).

AP3M1_HUMAN
NC score	0.853945 (rank : 9)	θ value	8.89434e-40 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y2T2	Gene names	AP3M1
Domain Architecture
Description	AP-3 complex subunit mu-1 (Adapter-related protein complex 3 mu-1 subunit) (Mu-adaptin 3A) (AP-3 adapter complex mu3A subunit).

AP3M1_MOUSE
NC score	0.853601 (rank : 10)	θ value	1.16164e-39 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JKC8, Q5BKQ6	Gene names	Ap3m1
Domain Architecture
Description	AP-3 complex subunit mu-1 (Adapter-related protein complex 3 mu-1 subunit) (Mu-adaptin 3A) (AP-3 adapter complex mu3A subunit).

AP3M2_MOUSE
NC score	0.845838 (rank : 11)	θ value	1.08726e-37 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R2R9, Q3UYJ3, Q923G7	Gene names	Ap3m2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit mu-2 (Adapter-related protein complex 3 mu-2 subunit) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Clathrin assembly protein assembly protein complex 1 medium chain homolog 2) (P47B) (m3B).

AP3M2_HUMAN
NC score	0.845744 (rank : 12)	θ value	2.19075e-38 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	P53677	Gene names	AP3M2
Domain Architecture
Description	AP-3 complex subunit mu-2 (Adapter-related protein complex 3 mu-2 subunit) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Clathrin assembly protein assembly protein complex 1 medium chain homolog 2) (P47B).

STON1_MOUSE
NC score	0.490571 (rank : 13)	θ value	1.33837e-11 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CDJ8, Q8CDL8, Q9D5T3	Gene names	Ston1, Salf, Sblf, Stn1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

STON2_HUMAN
NC score	0.469648 (rank : 14)	θ value	1.09485e-13 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	115	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

STON1_HUMAN
NC score	0.468718 (rank : 15)	θ value	3.64472e-09 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	49	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6Q2, Q96JE3, Q9BYX3	Gene names	STON1, SALF, SBLF, STN1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

STON2_MOUSE
NC score	0.462863 (rank : 16)	θ value	1.09485e-13 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	75	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BZ60	Gene names	Ston2, Stn2, Stnb
Domain Architecture
Description	Stonin-2 (Stoned B).

AP1S3_HUMAN
NC score	0.207818 (rank : 17)	θ value	0.0193708 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q96PC3, Q8WTY1, Q96DD1	Gene names	AP1S3
Domain Architecture
Description	AP-1 complex subunit sigma-3 (Adapter-related protein complex 1 sigma- 1C subunit) (Sigma-adaptin 1C) (Adaptor protein complex AP-1 sigma-1C subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1C subunit) (Clathrin assembly protein complex 1 sigma-1C small chain) (Sigma 1C subunit of AP-1 clathrin).

AP1S2_MOUSE
NC score	0.194393 (rank : 18)	θ value	0.0961366 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	Q9DB50, Q543R7	Gene names	Ap1s2
Domain Architecture
Description	AP-1 complex subunit sigma-2 (Adapter-related protein complex 1 sigma- 1B subunit) (Sigma-adaptin 1B) (Adaptor protein complex AP-1 sigma-1B subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Clathrin assembly protein complex 1 sigma-1B small chain) (Sigma 1B subunit of AP-1 clathrin).

AP1S2_HUMAN
NC score	0.191179 (rank : 19)	θ value	0.0961366 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	P56377, O95326, Q9H2N6	Gene names	AP1S2
Domain Architecture
Description	AP-1 complex subunit sigma-2 (Adapter-related protein complex 1 sigma- 1B subunit) (Sigma-adaptin 1B) (Adaptor protein complex AP-1 sigma-1B subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Clathrin assembly protein complex 1 sigma-1B small chain) (Sigma 1B subunit of AP-1 clathrin).

AP4S1_HUMAN
NC score	0.191032 (rank : 20)	θ value	0.163984 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y587	Gene names	AP4S1
Domain Architecture
Description	AP-4 complex subunit sigma-1 (Adapter-related protein complex 4 sigma- 1 subunit) (Sigma subunit of AP-4) (AP-4 adapter complex sigma subunit).

AP1S3_MOUSE
NC score	0.189776 (rank : 21)	θ value	0.0736092 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q7TN05	Gene names	Ap1s3
Domain Architecture	No domain graphic available
Description	AP-1 complex subunit sigma-3 (Adapter-related protein complex 1 sigma- 1C subunit) (Sigma-adaptin 1C) (Adaptor protein complex AP-1 sigma-1C subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1C subunit) (Clathrin assembly protein complex 1 sigma-1C small chain) (Sigma 1C subunit of AP-1 clathrin).

AP1S1_HUMAN
NC score	0.186226 (rank : 22)	θ value	0.163984 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P61966, P82267, Q00382, Q9BTN4, Q9UDW9	Gene names	AP1S1, AP19, CLAPS1
Domain Architecture
Description	AP-1 complex subunit sigma-1A (Adapter-related protein complex 1 sigma-1A subunit) (Sigma-adaptin 1A) (Adaptor protein complex AP-1 sigma-1A subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathrin coat assembly protein AP19) (HA1 19 kDa subunit) (Sigma 1a subunit of AP-1 clathrin).

AP1S1_MOUSE
NC score	0.186226 (rank : 23)	θ value	0.163984 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P61967, P82267, Q00382, Q9BTN4, Q9UDW9	Gene names	Ap1s1, Ap19
Domain Architecture
Description	AP-1 complex subunit sigma-1A (Adapter-related protein complex 1 sigma-1A subunit) (Sigma-adaptin 1A) (Adaptor protein complex AP-1 sigma-1A subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathrin coat assembly protein AP19) (HA1 19 kDa subunit) (Sigma 1a subunit of AP-1 clathrin).

AP4S1_MOUSE
NC score	0.168834 (rank : 24)	θ value	0.125558 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q9WVL1	Gene names	Ap4s1
Domain Architecture
Description	AP-4 complex subunit sigma-1 (Adapter-related protein complex 4 sigma- 1 subunit) (Sigma subunit of AP-4) (AP-4 adapter complex sigma subunit).

AP2S1_HUMAN
NC score	0.160393 (rank : 25)	θ value	0.0736092 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	P53680, O75977, Q6PK67	Gene names	AP2S1, AP17, CLAPS2
Domain Architecture
Description	AP-2 complex subunit sigma-1 (Adapter-related protein complex 2 sigma- 1 subunit) (Clathrin coat assembly protein AP17) (Clathrin coat- associated protein AP17) (Plasma membrane adaptor AP-2 17 kDa protein) (HA2 17 kDa subunit) (Clathrin assembly protein 2 small chain).

AP2S1_MOUSE
NC score	0.160393 (rank : 26)	θ value	0.0736092 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	P62743, P70626, P97626, Q00380	Gene names	Ap2s1, Ap17, Claps2
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit sigma-1 (Adapter-related protein complex 2 sigma- 1 subunit) (Sigma-adaptin 3b) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (Plasma membrane adaptor AP-2 17 kDa protein) (Clathrin assembly protein 2 small chain).

COPD_HUMAN
NC score	0.140744 (rank : 27)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	40	Shared Neighborhood Hits	18
SwissProt Accessions	P48444, Q52M80	Gene names	ARCN1, COPD
Domain Architecture
Description	Coatomer subunit delta (Delta-coat protein) (Delta-COP) (Archain).

COPD_MOUSE
NC score	0.140736 (rank : 28)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q5XJY5	Gene names	Arcn1, Copd
Domain Architecture	No domain graphic available
Description	Coatomer subunit delta (Delta-coat protein) (Delta-COP) (Archain).

CN108_HUMAN
NC score	0.096866 (rank : 29)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	33	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0R1, O95354, Q96DX3, Q9NVC5	Gene names	C14orf108
Domain Architecture
Description	Protein C14orf108 (Putative HIV-1 infection-related protein).

AP3S1_HUMAN
NC score	0.064303 (rank : 30)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	33	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q92572, O00647, O00676, O00721, O00727, Q6ICQ2	Gene names	AP3S1, CLAPS3
Domain Architecture
Description	AP-3 complex subunit sigma-1 (Adapter-related protein complex 3 sigma- 1 subunit) (Sigma-adaptin 3a) (AP-3 complex sigma-3A subunit) (Sigma- 3A-adaptin) (Clathrin-associated/assembly/adapter protein, small 3).

AP3S1_MOUSE
NC score	0.064303 (rank : 31)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	33	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DCR2, O88670	Gene names	Ap3s1
Domain Architecture
Description	AP-3 complex subunit sigma-1 (Adapter-related protein complex 3 sigma- 1 subunit) (Sigma-adaptin 3a) (AP-3 complex sigma-3A subunit) (Sigma- 3A-adaptin).

AP3S2_HUMAN
NC score	0.060722 (rank : 32)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	33	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	P59780, O09077, O09149, Q99589	Gene names	AP3S2
Domain Architecture
Description	AP-3 complex subunit sigma-2 (Adapter-related protein complex 3 sigma- 2 subunit) (Sigma-adaptin 3b) (AP-3 complex sigma-3B subunit) (Sigma- 3B-adaptin).

AP3S2_MOUSE
NC score	0.060722 (rank : 33)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	33	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BSZ2, O09077, O09149, Q3UDG7, Q8CAY1, Q99589	Gene names	Ap3s2
Domain Architecture
Description	AP-3 complex subunit sigma-2 (Adapter-related protein complex 3 sigma- 2 subunit) (Sigma-adaptin 3b) (AP-3 complex sigma-3B subunit) (Sigma- 3B-adaptin).

CN108_MOUSE
NC score	0.053509 (rank : 34)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	33	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJ63, Q3TPT5, Q8BII2, Q8BJ31, Q8BJ58, Q8BY11, Q8R5B1	Gene names
Domain Architecture
Description	Protein C14orf108 homolog.

GBRA2_HUMAN
NC score	0.018703 (rank : 35)	θ value	0.21417 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	P47869	Gene names	GABRA2
Domain Architecture
Description	Gamma-aminobutyric-acid receptor subunit alpha-2 precursor (GABA(A) receptor subunit alpha-2).

GBRA2_MOUSE
NC score	0.012599 (rank : 36)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	P26048	Gene names	Gabra2, Gabra-2
Domain Architecture
Description	Gamma-aminobutyric-acid receptor subunit alpha-2 precursor (GABA(A) receptor subunit alpha-2).

GBRA1_MOUSE
NC score	0.012359 (rank : 37)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	P62812, P18504	Gene names	Gabra1, Gabra-1
Domain Architecture	No domain graphic available
Description	Gamma-aminobutyric-acid receptor subunit alpha-1 precursor (GABA(A) receptor subunit alpha-1).

LRC33_HUMAN
NC score	0.007101 (rank : 38)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	293	Shared Neighborhood Hits	3
SwissProt Accessions	Q86YC3	Gene names	LRRC33
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 33 precursor.

CTGE2_HUMAN
NC score	0.003588 (rank : 39)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	594	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.