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Network neighborhood for query Sequence : WFD15_MOUSE

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WFD15_MOUSE
SwissProt Accessions	Q9JHY4, Q8BVC0	Gene names	Wfdc15, Swam1
Domain Architecture
Description	WAP four-disulfide core domain protein 15 precursor (Single WAP motif protein 1) (Elafin-like protein I).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

WFD15_MOUSE
θ value	3.15612e-45 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JHY4, Q8BVC0	Gene names	Wfdc15, Swam1
Domain Architecture
Description	WAP four-disulfide core domain protein 15 precursor (Single WAP motif protein 1) (Elafin-like protein I).

WFDC8_HUMAN
θ value	2.13673e-09 (rank : 2)	NC score	0.580176 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	82	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IUA0, Q5TDV2, Q96A34	Gene names	WFDC8, C20orf170, WAP8
Domain Architecture
Description	WAP four-disulfide core domain protein 8 precursor (Putative protease inhibitor WAP8).

EPPI_HUMAN
θ value	7.1131e-05 (rank : 3)	NC score	0.458725 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	33	Shared Neighborhood Hits	14
SwissProt Accessions	O95925, Q86TP9, Q96SD7, Q9HD30	Gene names	SPINLW1, WAP7, WFDC7
Domain Architecture
Description	Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1) (WAP four-disulfide core domain protein 7) (Protease inhibitor WAP7).

WFD12_HUMAN
θ value	0.00102713 (rank : 4)	NC score	0.549726 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WWY7, Q5H980, Q9BR31	Gene names	WFDC12, C20orf122, WAP2
Domain Architecture
Description	WAP four-disulfide core domain protein 12 precursor (Putative protease inhibitor WAP12) (Whey acidic protein 2).

EPPI_MOUSE
θ value	0.00134147 (rank : 5)	NC score	0.442974 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DA01	Gene names	Spinlw1
Domain Architecture
Description	Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1).

WFDC6_HUMAN
θ value	0.00509761 (rank : 6)	NC score	0.488225 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	33	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BQY6, Q5JYQ4, Q8NFV6	Gene names	WFDC6, C20orf171, WAP6
Domain Architecture
Description	WAP four-disulfide core domain protein 6 precursor (Putative protease inhibitor WAP6).

WFDC5_HUMAN
θ value	0.0193708 (rank : 7)	NC score	0.442590 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TCV5, Q6UWE4	Gene names	WFDC5, WAP1
Domain Architecture
Description	WAP four-disulfide core domain protein 5 precursor (Putative protease inhibitor WAP1).

WFDC2_MOUSE
θ value	0.0252991 (rank : 8)	NC score	0.351113 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	30	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DAU7	Gene names	Wfdc2, He4
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (WAP domain- containing protein HE4).

ALK1_HUMAN
θ value	0.0330416 (rank : 9)	NC score	0.452294 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	33	Shared Neighborhood Hits	15
SwissProt Accessions	P03973, P07757	Gene names	SLPI, WAP4, WFDC4
Domain Architecture
Description	Antileukoproteinase 1 precursor (ALP) (HUSI-1) (Seminal proteinase inhibitor) (Secretory leukocyte protease inhibitor) (BLPI) (Mucus proteinase inhibitor) (MPI) (WAP four-disulfide core domain protein 4) (Protease inhibitor WAP4).

ALK1_MOUSE
θ value	0.0330416 (rank : 10)	NC score	0.466017 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	43	Shared Neighborhood Hits	15
SwissProt Accessions	P97430, O09081, O09082	Gene names	Slpi
Domain Architecture
Description	Antileukoproteinase 1 precursor (ALP) (Secretory leukocyte protease inhibitor).

ELAF_HUMAN
θ value	0.0330416 (rank : 11)	NC score	0.454040 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	P19957	Gene names	PI3, WAP3, WFDC14
Domain Architecture
Description	Elafin precursor (Elastase-specific inhibitor) (ESI) (Skin-derived antileukoproteinase) (SKALP) (WAP four-disulfide core domain protein 14) (Protease inhibitor WAP3).

WAP_MOUSE
θ value	0.125558 (rank : 12)	NC score	0.357929 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	P01173, P70230, Q61023	Gene names	Wap
Domain Architecture
Description	Whey acidic protein precursor (WAP).

WFD12_MOUSE
θ value	0.163984 (rank : 13)	NC score	0.441870 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JHY3	Gene names	Wfdc12, Swam2
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 12 precursor (Whey acidic protein 2) (Single WAP motif protein 2) (Elafin-like protein II).

UROL1_MOUSE
θ value	1.38821 (rank : 14)	NC score	0.100690 (rank : 23)
Query Neighborhood Hits	17	Target Neighborhood Hits	235	Shared Neighborhood Hits	13
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

WFDC3_HUMAN
θ value	4.03905 (rank : 15)	NC score	0.261363 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	138	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

SIA8C_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.022458 (rank : 39)
Query Neighborhood Hits	17	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	O43173, Q9NS41	Gene names	ST8SIA3, SIAT8C
Domain Architecture
Description	Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase (EC 2.4.99.-) (ST8 alpha-N-acetyl-neuraminide alpha-2,8- sialyltransferase 3) (Alpha-2,8-sialyltransferase 8C) (Alpha-2,8- sialyltransferase III) (ST8Sia III).

SIA8C_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.022749 (rank : 38)
Query Neighborhood Hits	17	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q64689	Gene names	St8sia3, Siat8c
Domain Architecture
Description	Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase (EC 2.4.99.-) (ST8 alpha-N-acetyl-neuraminide alpha-2,8- sialyltransferase 3) (Alpha-2,8-sialyltransferase 8C) (Alpha-2,8- sialyltransferase III) (ST8Sia III).

A4_HUMAN
θ value	θ > 10 (rank : 18)	NC score	0.068697 (rank : 33)
Query Neighborhood Hits	17	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

A4_MOUSE
θ value	θ > 10 (rank : 19)	NC score	0.067674 (rank : 35)
Query Neighborhood Hits	17	Target Neighborhood Hits	275	Shared Neighborhood Hits	4
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

AMBP_HUMAN
θ value	θ > 10 (rank : 20)	NC score	0.091486 (rank : 25)
Query Neighborhood Hits	17	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	P02760, P00977, P02759	Gene names	AMBP, HCP, ITIL
Domain Architecture
Description	AMBP protein precursor [Contains: Alpha-1-microglobulin (Protein HC) (Complex-forming glycoprotein heterogeneous in charge) (Alpha-1 microglycoprotein); Inter-alpha-trypsin inhibitor light chain (ITI-LC) (Bikunin) (HI-30)].

AMBP_MOUSE
θ value	θ > 10 (rank : 21)	NC score	0.084488 (rank : 27)
Query Neighborhood Hits	17	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q07456, Q61294	Gene names	Ambp, Itil
Domain Architecture
Description	AMBP protein precursor [Contains: Alpha-1-microglobulin; Inter-alpha- trypsin inhibitor light chain (ITI-LC) (Bikunin) (HI-30)].

APLP2_HUMAN
θ value	θ > 10 (rank : 22)	NC score	0.068811 (rank : 32)
Query Neighborhood Hits	17	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

EXPI_MOUSE
θ value	θ > 10 (rank : 23)	NC score	0.272261 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	P62810, Q62477, Q91VQ6	Gene names	Expi, Wdnm1
Domain Architecture	No domain graphic available
Description	Extracellular peptidase inhibitor precursor (Protein WDNM1).

KALM_HUMAN
θ value	θ > 10 (rank : 24)	NC score	0.109862 (rank : 20)
Query Neighborhood Hits	17	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

MCSP_MOUSE
θ value	θ > 10 (rank : 25)	NC score	0.074911 (rank : 30)
Query Neighborhood Hits	17	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

SPIT1_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.068879 (rank : 31)
Query Neighborhood Hits	17	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPIT1_MOUSE
θ value	θ > 10 (rank : 27)	NC score	0.077662 (rank : 28)
Query Neighborhood Hits	17	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPIT2_HUMAN
θ value	θ > 10 (rank : 28)	NC score	0.102827 (rank : 22)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	O43291, O00271, O14895, Q5TZQ3, Q969E0	Gene names	SPINT2, HAI2, KOP
Domain Architecture
Description	Kunitz-type protease inhibitor 2 precursor (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin).

SPIT2_MOUSE
θ value	θ > 10 (rank : 29)	NC score	0.106516 (rank : 21)
Query Neighborhood Hits	17	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WU03, Q9WU04, Q9WU05	Gene names	Spint2, Hai2
Domain Architecture
Description	Kunitz-type protease inhibitor 2 precursor (Hepatocyte growth factor activator inhibitor type 2) (HAI-2).

SPIT3_HUMAN
θ value	θ > 10 (rank : 30)	NC score	0.149965 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	P49223, Q6UDR8, Q96KK2	Gene names	SPINT3
Domain Architecture	No domain graphic available
Description	Kunitz-type protease inhibitor 3 precursor (HKIB9).

TFPI1_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.095387 (rank : 24)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	P10646, O95103	Gene names	TFPI, LACI, TFPI1
Domain Architecture
Description	Tissue factor pathway inhibitor precursor (TFPI) (Lipoprotein- associated coagulation inhibitor) (LACI) (Extrinsic pathway inhibitor) (EPI).

TFPI1_MOUSE
θ value	θ > 10 (rank : 32)	NC score	0.086256 (rank : 26)
Query Neighborhood Hits	17	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	O54819, Q9Z2U8	Gene names	Tfpi
Domain Architecture
Description	Tissue factor pathway inhibitor precursor (TFPI) (Lipoprotein- associated coagulation inhibitor) (LACI) (Extrinsic pathway inhibitor) (EPI).

TFPI2_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.111230 (rank : 18)
Query Neighborhood Hits	17	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P48307	Gene names	TFPI2
Domain Architecture
Description	Tissue factor pathway inhibitor 2 precursor (TFPI-2) (Placental protein 5) (PP5).

TFPI2_MOUSE
θ value	θ > 10 (rank : 34)	NC score	0.111161 (rank : 19)
Query Neighborhood Hits	17	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	O35536	Gene names	Tfpi2
Domain Architecture
Description	Tissue factor pathway inhibitor 2 precursor (TFPI-2).

UROL1_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.076558 (rank : 29)
Query Neighborhood Hits	17	Target Neighborhood Hits	213	Shared Neighborhood Hits	12
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

WFD13_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.050333 (rank : 37)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IUB5, Q5TEU7, Q8WWK7	Gene names	WFDC13, C20orf138, WAP13
Domain Architecture	No domain graphic available
Description	Protein WFDC13 precursor.

WFDC1_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.064112 (rank : 36)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HC57, Q8NC27, Q9HAU1	Gene names	WFDC1, PS20
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 1 precursor (Prostate stromal protein ps20) (ps20 growth inhibitor).

WFDC1_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.068137 (rank : 34)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ESH5, Q8R110	Gene names	Wfdc1, Ps20
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 1 precursor (Prostate stromal protein ps20) (ps20 growth inhibitor).

WFDC2_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.274498 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

Hits sorted by NC score

WFD15_MOUSE
NC score	0.999962 (rank : 1)	θ value	3.15612e-45 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JHY4, Q8BVC0	Gene names	Wfdc15, Swam1
Domain Architecture
Description	WAP four-disulfide core domain protein 15 precursor (Single WAP motif protein 1) (Elafin-like protein I).

WFDC8_HUMAN
NC score	0.580176 (rank : 2)	θ value	2.13673e-09 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	82	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IUA0, Q5TDV2, Q96A34	Gene names	WFDC8, C20orf170, WAP8
Domain Architecture
Description	WAP four-disulfide core domain protein 8 precursor (Putative protease inhibitor WAP8).

WFD12_HUMAN
NC score	0.549726 (rank : 3)	θ value	0.00102713 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WWY7, Q5H980, Q9BR31	Gene names	WFDC12, C20orf122, WAP2
Domain Architecture
Description	WAP four-disulfide core domain protein 12 precursor (Putative protease inhibitor WAP12) (Whey acidic protein 2).

WFDC6_HUMAN
NC score	0.488225 (rank : 4)	θ value	0.00509761 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	33	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BQY6, Q5JYQ4, Q8NFV6	Gene names	WFDC6, C20orf171, WAP6
Domain Architecture
Description	WAP four-disulfide core domain protein 6 precursor (Putative protease inhibitor WAP6).

ALK1_MOUSE
NC score	0.466017 (rank : 5)	θ value	0.0330416 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	43	Shared Neighborhood Hits	15
SwissProt Accessions	P97430, O09081, O09082	Gene names	Slpi
Domain Architecture
Description	Antileukoproteinase 1 precursor (ALP) (Secretory leukocyte protease inhibitor).

EPPI_HUMAN
NC score	0.458725 (rank : 6)	θ value	7.1131e-05 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	33	Shared Neighborhood Hits	14
SwissProt Accessions	O95925, Q86TP9, Q96SD7, Q9HD30	Gene names	SPINLW1, WAP7, WFDC7
Domain Architecture
Description	Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1) (WAP four-disulfide core domain protein 7) (Protease inhibitor WAP7).

ELAF_HUMAN
NC score	0.454040 (rank : 7)	θ value	0.0330416 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	15
SwissProt Accessions	P19957	Gene names	PI3, WAP3, WFDC14
Domain Architecture
Description	Elafin precursor (Elastase-specific inhibitor) (ESI) (Skin-derived antileukoproteinase) (SKALP) (WAP four-disulfide core domain protein 14) (Protease inhibitor WAP3).

ALK1_HUMAN
NC score	0.452294 (rank : 8)	θ value	0.0330416 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	33	Shared Neighborhood Hits	15
SwissProt Accessions	P03973, P07757	Gene names	SLPI, WAP4, WFDC4
Domain Architecture
Description	Antileukoproteinase 1 precursor (ALP) (HUSI-1) (Seminal proteinase inhibitor) (Secretory leukocyte protease inhibitor) (BLPI) (Mucus proteinase inhibitor) (MPI) (WAP four-disulfide core domain protein 4) (Protease inhibitor WAP4).

EPPI_MOUSE
NC score	0.442974 (rank : 9)	θ value	0.00134147 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DA01	Gene names	Spinlw1
Domain Architecture
Description	Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1).

WFDC5_HUMAN
NC score	0.442590 (rank : 10)	θ value	0.0193708 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TCV5, Q6UWE4	Gene names	WFDC5, WAP1
Domain Architecture
Description	WAP four-disulfide core domain protein 5 precursor (Putative protease inhibitor WAP1).

WFD12_MOUSE
NC score	0.441870 (rank : 11)	θ value	0.163984 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JHY3	Gene names	Wfdc12, Swam2
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 12 precursor (Whey acidic protein 2) (Single WAP motif protein 2) (Elafin-like protein II).

WAP_MOUSE
NC score	0.357929 (rank : 12)	θ value	0.125558 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	P01173, P70230, Q61023	Gene names	Wap
Domain Architecture
Description	Whey acidic protein precursor (WAP).

WFDC2_MOUSE
NC score	0.351113 (rank : 13)	θ value	0.0252991 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	30	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DAU7	Gene names	Wfdc2, He4
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (WAP domain- containing protein HE4).

WFDC2_HUMAN
NC score	0.274498 (rank : 14)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	17	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

EXPI_MOUSE
NC score	0.272261 (rank : 15)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	17	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	P62810, Q62477, Q91VQ6	Gene names	Expi, Wdnm1
Domain Architecture	No domain graphic available
Description	Extracellular peptidase inhibitor precursor (Protein WDNM1).

WFDC3_HUMAN
NC score	0.261363 (rank : 16)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	138	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

SPIT3_HUMAN
NC score	0.149965 (rank : 17)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	P49223, Q6UDR8, Q96KK2	Gene names	SPINT3
Domain Architecture	No domain graphic available
Description	Kunitz-type protease inhibitor 3 precursor (HKIB9).

TFPI2_HUMAN
NC score	0.111230 (rank : 18)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	17	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P48307	Gene names	TFPI2
Domain Architecture
Description	Tissue factor pathway inhibitor 2 precursor (TFPI-2) (Placental protein 5) (PP5).

TFPI2_MOUSE
NC score	0.111161 (rank : 19)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	17	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	O35536	Gene names	Tfpi2
Domain Architecture
Description	Tissue factor pathway inhibitor 2 precursor (TFPI-2).

KALM_HUMAN
NC score	0.109862 (rank : 20)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	17	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

SPIT2_MOUSE
NC score	0.106516 (rank : 21)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	17	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WU03, Q9WU04, Q9WU05	Gene names	Spint2, Hai2
Domain Architecture
Description	Kunitz-type protease inhibitor 2 precursor (Hepatocyte growth factor activator inhibitor type 2) (HAI-2).

SPIT2_HUMAN
NC score	0.102827 (rank : 22)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	O43291, O00271, O14895, Q5TZQ3, Q969E0	Gene names	SPINT2, HAI2, KOP
Domain Architecture
Description	Kunitz-type protease inhibitor 2 precursor (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin).

UROL1_MOUSE
NC score	0.100690 (rank : 23)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	235	Shared Neighborhood Hits	13
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

TFPI1_HUMAN
NC score	0.095387 (rank : 24)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	P10646, O95103	Gene names	TFPI, LACI, TFPI1
Domain Architecture
Description	Tissue factor pathway inhibitor precursor (TFPI) (Lipoprotein- associated coagulation inhibitor) (LACI) (Extrinsic pathway inhibitor) (EPI).

AMBP_HUMAN
NC score	0.091486 (rank : 25)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	17	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	P02760, P00977, P02759	Gene names	AMBP, HCP, ITIL
Domain Architecture
Description	AMBP protein precursor [Contains: Alpha-1-microglobulin (Protein HC) (Complex-forming glycoprotein heterogeneous in charge) (Alpha-1 microglycoprotein); Inter-alpha-trypsin inhibitor light chain (ITI-LC) (Bikunin) (HI-30)].

TFPI1_MOUSE
NC score	0.086256 (rank : 26)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	17	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	O54819, Q9Z2U8	Gene names	Tfpi
Domain Architecture
Description	Tissue factor pathway inhibitor precursor (TFPI) (Lipoprotein- associated coagulation inhibitor) (LACI) (Extrinsic pathway inhibitor) (EPI).

AMBP_MOUSE
NC score	0.084488 (rank : 27)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	17	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q07456, Q61294	Gene names	Ambp, Itil
Domain Architecture
Description	AMBP protein precursor [Contains: Alpha-1-microglobulin; Inter-alpha- trypsin inhibitor light chain (ITI-LC) (Bikunin) (HI-30)].

SPIT1_MOUSE
NC score	0.077662 (rank : 28)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	17	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

UROL1_HUMAN
NC score	0.076558 (rank : 29)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	17	Target Neighborhood Hits	213	Shared Neighborhood Hits	12
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

MCSP_MOUSE
NC score	0.074911 (rank : 30)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	17	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

SPIT1_HUMAN
NC score	0.068879 (rank : 31)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	17	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

APLP2_HUMAN
NC score	0.068811 (rank : 32)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	17	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

A4_HUMAN
NC score	0.068697 (rank : 33)	θ value	θ > 10 (rank : 18)
Query Neighborhood Hits	17	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

WFDC1_MOUSE
NC score	0.068137 (rank : 34)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ESH5, Q8R110	Gene names	Wfdc1, Ps20
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 1 precursor (Prostate stromal protein ps20) (ps20 growth inhibitor).

A4_MOUSE
NC score	0.067674 (rank : 35)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	17	Target Neighborhood Hits	275	Shared Neighborhood Hits	4
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

WFDC1_HUMAN
NC score	0.064112 (rank : 36)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HC57, Q8NC27, Q9HAU1	Gene names	WFDC1, PS20
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 1 precursor (Prostate stromal protein ps20) (ps20 growth inhibitor).

WFD13_HUMAN
NC score	0.050333 (rank : 37)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IUB5, Q5TEU7, Q8WWK7	Gene names	WFDC13, C20orf138, WAP13
Domain Architecture	No domain graphic available
Description	Protein WFDC13 precursor.

SIA8C_MOUSE
NC score	0.022749 (rank : 38)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q64689	Gene names	St8sia3, Siat8c
Domain Architecture
Description	Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase (EC 2.4.99.-) (ST8 alpha-N-acetyl-neuraminide alpha-2,8- sialyltransferase 3) (Alpha-2,8-sialyltransferase 8C) (Alpha-2,8- sialyltransferase III) (ST8Sia III).

SIA8C_HUMAN
NC score	0.022458 (rank : 39)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	O43173, Q9NS41	Gene names	ST8SIA3, SIAT8C
Domain Architecture
Description	Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase (EC 2.4.99.-) (ST8 alpha-N-acetyl-neuraminide alpha-2,8- sialyltransferase 3) (Alpha-2,8-sialyltransferase 8C) (Alpha-2,8- sialyltransferase III) (ST8Sia III).