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Network neighborhood for query Sequence : UBXD1_MOUSE

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UBXD1_MOUSE
SwissProt Accessions	Q99PL6, Q91W79	Gene names	Ubxd1, Ubxdc2
Domain Architecture
Description	UBX domain-containing protein 1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBXD1_HUMAN
θ value	0 (rank : 1)	NC score	0.983379 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BZV1, Q96AH1, Q96IK9, Q9BZV0	Gene names	UBXD1, UBXDC2
Domain Architecture
Description	UBX domain-containing protein 1.

UBXD1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PL6, Q91W79	Gene names	Ubxd1, Ubxdc2
Domain Architecture
Description	UBX domain-containing protein 1.

ASPC1_MOUSE
θ value	1.9326e-10 (rank : 3)	NC score	0.456265 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VBT9, Q3UKD1, Q6V7K5, Q9CT64	Gene names	Aspscr1, Tug
Domain Architecture	No domain graphic available
Description	Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosome region candidate 1 homolog).

ASPC1_HUMAN
θ value	2.52405e-10 (rank : 4)	NC score	0.479392 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZE9, Q7Z6N7, Q8WV59, Q96LS5, Q96M40	Gene names	ASPSCR1, ASPL, RCC17, TUG
Domain Architecture	No domain graphic available
Description	Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosome region candidate 1) (Alveolar soft part sarcoma locus) (Renal papillary cell carcinoma protein 17).

SAKS1_MOUSE
θ value	0.000786445 (rank : 5)	NC score	0.251327 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	208	Shared Neighborhood Hits	17
SwissProt Accessions	Q922Y1, Q3UCP8	Gene names	Saks1, D19Ertd721e
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein) (mY33K) (Protein 2B28).

FAF1_MOUSE
θ value	0.00102713 (rank : 6)	NC score	0.219298 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	107	Shared Neighborhood Hits	10
SwissProt Accessions	P54731	Gene names	Faf1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1).

SAKS1_HUMAN
θ value	0.00102713 (rank : 7)	NC score	0.260991 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	202	Shared Neighborhood Hits	13
SwissProt Accessions	Q04323, Q9BV93, Q9BVV5	Gene names	SAKS1
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein).

FAF1_HUMAN
θ value	0.00134147 (rank : 8)	NC score	0.214298 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	105	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UNN5, Q9UF34, Q9UNT3, Q9Y2Z3	Gene names	FAF1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1) (hFAF1).

CING_MOUSE
θ value	0.00665767 (rank : 9)	NC score	0.070678 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	1432	Shared Neighborhood Hits	28
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CING_HUMAN
θ value	0.00869519 (rank : 10)	NC score	0.072997 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	1275	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

MERL_HUMAN
θ value	0.0563607 (rank : 11)	NC score	0.054466 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	532	Shared Neighborhood Hits	25
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	0.0563607 (rank : 12)	NC score	0.054701 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	524	Shared Neighborhood Hits	25
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

PEPL_HUMAN
θ value	0.0961366 (rank : 13)	NC score	0.047581 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	1141	Shared Neighborhood Hits	29
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

NGLY1_HUMAN
θ value	0.125558 (rank : 14)	NC score	0.134317 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q96IV0, Q59FB1, Q6PJD8, Q9BVR8, Q9NR70	Gene names	NGLY1, PNG1
Domain Architecture	No domain graphic available
Description	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (EC 3.5.1.52) (PNGase) (hPNGase) (Peptide:N-glycanase) (N-glycanase 1).

NGLY1_MOUSE
θ value	0.125558 (rank : 15)	NC score	0.135611 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JI78, Q8K113, Q9CTK3	Gene names	Ngly1
Domain Architecture	No domain graphic available
Description	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (EC 3.5.1.52) (PNGase) (mPNGase) (Peptide:N-glycanase) (N-glycanase 1).

M4K4_HUMAN
θ value	0.813845 (rank : 16)	NC score	0.016817 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	1589	Shared Neighborhood Hits	26
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
θ value	0.813845 (rank : 17)	NC score	0.016243 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	1560	Shared Neighborhood Hits	24
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

CCD96_HUMAN
θ value	1.81305 (rank : 18)	NC score	0.048766 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	595	Shared Neighborhood Hits	26
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

IF3A_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.045182 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	875	Shared Neighborhood Hits	28
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

MACF1_HUMAN
θ value	1.81305 (rank : 20)	NC score	0.035917 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	1341	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	1.81305 (rank : 21)	NC score	0.037042 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	1321	Shared Neighborhood Hits	25
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

CCHCR_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.049834 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	717	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

TRHY_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.039518 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	1385	Shared Neighborhood Hits	26
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

IF3A_MOUSE
θ value	4.03905 (rank : 24)	NC score	0.043053 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	871	Shared Neighborhood Hits	28
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

RABE2_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.041300 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	598	Shared Neighborhood Hits	24
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

CADH5_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.004182 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	P33151	Gene names	CDH5
Domain Architecture
Description	Cadherin-5 precursor (Vascular endothelial-cadherin) (VE-cadherin) (7B4 antigen) (CD144 antigen).

CCD41_MOUSE
θ value	5.27518 (rank : 27)	NC score	0.031904 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	1399	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCHCR_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.044287 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	932	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

MYH11_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.026644 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	1806	Shared Neighborhood Hits	28
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	5.27518 (rank : 30)	NC score	0.026056 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	1777	Shared Neighborhood Hits	27
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NEST_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.029471 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	1305	Shared Neighborhood Hits	27
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

SMC1A_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.032445 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	1346	Shared Neighborhood Hits	26
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.033131 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	1384	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

STX4_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.019943 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	312	Shared Neighborhood Hits	15
SwissProt Accessions	P70452	Gene names	Stx4, Stx4a
Domain Architecture
Description	Syntaxin-4.

ATS13_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.004953 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	227	Shared Neighborhood Hits	2
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

DDX21_MOUSE
θ value	8.99809 (rank : 36)	NC score	0.004451 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	350	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

MYH9_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.027266 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	1762	Shared Neighborhood Hits	29
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

PLEC1_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.031625 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	1326	Shared Neighborhood Hits	27
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

RNF31_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.022388 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

SPTN5_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.023061 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	674	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

Hits sorted by NC score

UBXD1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PL6, Q91W79	Gene names	Ubxd1, Ubxdc2
Domain Architecture
Description	UBX domain-containing protein 1.

UBXD1_HUMAN
NC score	0.983379 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BZV1, Q96AH1, Q96IK9, Q9BZV0	Gene names	UBXD1, UBXDC2
Domain Architecture
Description	UBX domain-containing protein 1.

ASPC1_HUMAN
NC score	0.479392 (rank : 3)	θ value	2.52405e-10 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZE9, Q7Z6N7, Q8WV59, Q96LS5, Q96M40	Gene names	ASPSCR1, ASPL, RCC17, TUG
Domain Architecture	No domain graphic available
Description	Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosome region candidate 1) (Alveolar soft part sarcoma locus) (Renal papillary cell carcinoma protein 17).

ASPC1_MOUSE
NC score	0.456265 (rank : 4)	θ value	1.9326e-10 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VBT9, Q3UKD1, Q6V7K5, Q9CT64	Gene names	Aspscr1, Tug
Domain Architecture	No domain graphic available
Description	Tether containing UBX domain for GLUT4 (Alveolar soft part sarcoma chromosome region candidate 1 homolog).

SAKS1_HUMAN
NC score	0.260991 (rank : 5)	θ value	0.00102713 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	202	Shared Neighborhood Hits	13
SwissProt Accessions	Q04323, Q9BV93, Q9BVV5	Gene names	SAKS1
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein).

SAKS1_MOUSE
NC score	0.251327 (rank : 6)	θ value	0.000786445 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	208	Shared Neighborhood Hits	17
SwissProt Accessions	Q922Y1, Q3UCP8	Gene names	Saks1, D19Ertd721e
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein) (mY33K) (Protein 2B28).

FAF1_MOUSE
NC score	0.219298 (rank : 7)	θ value	0.00102713 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	107	Shared Neighborhood Hits	10
SwissProt Accessions	P54731	Gene names	Faf1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1).

FAF1_HUMAN
NC score	0.214298 (rank : 8)	θ value	0.00134147 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	105	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UNN5, Q9UF34, Q9UNT3, Q9Y2Z3	Gene names	FAF1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1) (hFAF1).

NGLY1_MOUSE
NC score	0.135611 (rank : 9)	θ value	0.125558 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JI78, Q8K113, Q9CTK3	Gene names	Ngly1
Domain Architecture	No domain graphic available
Description	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (EC 3.5.1.52) (PNGase) (mPNGase) (Peptide:N-glycanase) (N-glycanase 1).

NGLY1_HUMAN
NC score	0.134317 (rank : 10)	θ value	0.125558 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q96IV0, Q59FB1, Q6PJD8, Q9BVR8, Q9NR70	Gene names	NGLY1, PNG1
Domain Architecture	No domain graphic available
Description	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (EC 3.5.1.52) (PNGase) (hPNGase) (Peptide:N-glycanase) (N-glycanase 1).

CING_HUMAN
NC score	0.072997 (rank : 11)	θ value	0.00869519 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	1275	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CING_MOUSE
NC score	0.070678 (rank : 12)	θ value	0.00665767 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	1432	Shared Neighborhood Hits	28
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

MERL_MOUSE
NC score	0.054701 (rank : 13)	θ value	0.0563607 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	524	Shared Neighborhood Hits	25
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MERL_HUMAN
NC score	0.054466 (rank : 14)	θ value	0.0563607 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	532	Shared Neighborhood Hits	25
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

CCHCR_HUMAN
NC score	0.049834 (rank : 15)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	717	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CCD96_HUMAN
NC score	0.048766 (rank : 16)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	595	Shared Neighborhood Hits	26
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

PEPL_HUMAN
NC score	0.047581 (rank : 17)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	1141	Shared Neighborhood Hits	29
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

IF3A_HUMAN
NC score	0.045182 (rank : 18)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	875	Shared Neighborhood Hits	28
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

CCHCR_MOUSE
NC score	0.044287 (rank : 19)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	932	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

IF3A_MOUSE
NC score	0.043053 (rank : 20)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	871	Shared Neighborhood Hits	28
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

RABE2_MOUSE
NC score	0.041300 (rank : 21)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	598	Shared Neighborhood Hits	24
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

TRHY_HUMAN
NC score	0.039518 (rank : 22)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	1385	Shared Neighborhood Hits	26
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

MACF4_HUMAN
NC score	0.037042 (rank : 23)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	1321	Shared Neighborhood Hits	25
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MACF1_HUMAN
NC score	0.035917 (rank : 24)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	1341	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

SMC1A_MOUSE
NC score	0.033131 (rank : 25)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	1384	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SMC1A_HUMAN
NC score	0.032445 (rank : 26)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	1346	Shared Neighborhood Hits	26
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

CCD41_MOUSE
NC score	0.031904 (rank : 27)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	1399	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

PLEC1_HUMAN
NC score	0.031625 (rank : 28)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	1326	Shared Neighborhood Hits	27
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

NEST_HUMAN
NC score	0.029471 (rank : 29)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	1305	Shared Neighborhood Hits	27
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

MYH9_HUMAN
NC score	0.027266 (rank : 30)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	1762	Shared Neighborhood Hits	29
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH11_HUMAN
NC score	0.026644 (rank : 31)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	1806	Shared Neighborhood Hits	28
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
NC score	0.026056 (rank : 32)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	1777	Shared Neighborhood Hits	27
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

SPTN5_HUMAN
NC score	0.023061 (rank : 33)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	674	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

RNF31_HUMAN
NC score	0.022388 (rank : 34)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

STX4_MOUSE
NC score	0.019943 (rank : 35)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	312	Shared Neighborhood Hits	15
SwissProt Accessions	P70452	Gene names	Stx4, Stx4a
Domain Architecture
Description	Syntaxin-4.

M4K4_HUMAN
NC score	0.016817 (rank : 36)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	1589	Shared Neighborhood Hits	26
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
NC score	0.016243 (rank : 37)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	1560	Shared Neighborhood Hits	24
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

ATS13_MOUSE
NC score	0.004953 (rank : 38)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	227	Shared Neighborhood Hits	2
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

DDX21_MOUSE
NC score	0.004451 (rank : 39)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	350	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

CADH5_HUMAN
NC score	0.004182 (rank : 40)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	P33151	Gene names	CDH5
Domain Architecture
Description	Cadherin-5 precursor (Vascular endothelial-cadherin) (VE-cadherin) (7B4 antigen) (CD144 antigen).